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Hepion Pharmaceuticals, Inc. (HEPA)

USD0.06 -0.01 (-8.33%)
US OTC Healthcare Biotechnology
Address 399 Thornall Street 8837
Edison, NJ, US
CEO Gary S. Stetz
IPO 2014-02-10
CIK 1583771 ISIN US4268974015

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Description

Hepion Pharmaceuticals, Inc., a U.S.-based biopharmaceutical entity, is dedicated to developing therapeutic interventions for chronic hepatic ailments. Central to their efforts is Rencofilstat, a cyclophilin inhibitor that has successfully concluded Phase 2a clinical trials. This compound operates by disrupting multiple pathological pathways implicated in the worsening of liver disease. It is currently progressing through clinical development for non-alcoholic steatohepatitis (NASH) and is additionally being explored in nonclinical research for its potential to reduce liver fibrosis and lessen hepatocellular carcinoma tumor loads in experimental models of NASH. Moreover, Rencofilstat has exhibited antiviral properties against hepatitis B, C, and D viruses through diverse mechanisms. The company, established in 2013 and situated in Edison, New Jersey, rebranded as Hepion Pharmaceuticals, Inc. in July 2019, having previously operated as ContraVir Pharmaceuticals, Inc.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD0.06 -0.01 (-8.33%)
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Volume Profile
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Liquidity & share structure
Average Volume
22.2K
Beta
1.66
Float Shares
11.62M
Free Float %
100.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-2.11% +54.39% +83.33% +46.67% +23.94% +46.67% -27.87% -99.97% -99.99% -100.00% -100.00%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (3 ratings, all time) Hold
Price Targets & DCF
Current price
0.06
Low 70.00 +127,172.7%
Consensus 70.00 +127,172.7%
Median 70.00 +127,172.7%
High 70.00 +127,172.7%
DCF (Unlevered) 0.17 +214.4%
DCF (Levered) 0.19 +242.8%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2024-11 Change
Strong Buy 0 0
Buy 1 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year
All Time 1
70.00
+127,172.7%
Quality scores
Altman Z-Score
-129.79
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
B
Overall Score
3 / 5
Medium
DCF Score
5 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +99.2% Q1'26: +96.7% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -923.7% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +7,556.5% Q1'26: +309.6% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: 0.00× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.65) × ERP
WACC = 93% × Ke + 7% × Kd (45.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.17 Current price: 0.06
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2018
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 EPS Ana.
Dec 2027
1 EPS Ana.
Revenue
est: 20.30M (-100.0%)
— – —
— – —
EBITDA
-14.58M
-14.88M
-8.25M
— – —
— – —
EBIT
-14.59M
-14.91M
-8.25M
— – —
— – —
Net Income
-9.45M
est: -8.95B (+99.9%)
-13.19M
est: -70.23M (+81.2%)
-8.28M
est: -2.94B (+99.7%)
-4.44B
-4.44B – -4.44B
-51.0% YoY
-4.40B
-4.40B – -4.40B
+0.8% YoY
SGA
7.00M
7.50M
3.32M
— – —
— – —
EPS
-97,353.00
est: -72,800.00 (-33.7%)
-107.35
est: -571.50 (+81.2%)
-0.88
est: -312.50 (+99.7%)
-472.00
-472.00 – -472.00
-51.0% YoY
-468.00
-468.00 – -468.00
+0.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-08 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-07 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-06 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-05 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-04 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-05-01 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-04-30 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-04-29 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-04-28 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-04-27 B 3/5 5/5 1/5 1/5 3/5 1/5 5/5
2026-04-24 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-23 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-22 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-21 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-20 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-17 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5
2026-04-16 B- 3/5 5/5 1/5 1/5 2/5 1/5 5/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
4
Beneficial owners (>5%)
25
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 NAME OF REPORTING PERSONS 5.00M 9.00% 5.00M 5.00M Cayman Islands 2021-02-19
2 Donald E. Garlikov 3.41M 16.57% 3.41M 3.41M IN USA 2019-04-02
3 The Vanguard Group - 23-1945930 3.33M 4.36% 17.5K 3.28M 44.3K IA Pennsylvania For 2022-02-10
4 (. 1.17M 4.00% 1.17M 1.17M IN United States 2020-12-28
5 27-4413262 1.17M 4.00% 1.17M 1.17M OO Maryland 2020-12-28
6 CVI Investments, Inc. 420.0K 1.30% 420.0K 420.0K CO Cayman Islands 2021-02-16
7 Heights Capital Management, Inc. 420.0K 1.30% 420.0K 420.0K CO Cayman Islands 2021-02-16
8 Armistice Capital, LLC 418.0K 8.67% 418.0K IA, OO Delaware 2024-02-14
9 Steven Boyd 418.0K 8.67% 418.0K HC, IN Delaware 2024-02-14
10 2 359.9K 9.90% 359.9K CO Texas 2019-06-28
11 Empery Asset Management, LP 335.7K 0.44% 335.7K 335.7K PN Delaware 2022-01-19
12 Hudson Bay Capital Management LP 295.9K 0.92% 295.9K PN State of Delaware 2021-02-09
13 Sander Gerber 295.9K 0.92% 295.9K IN United States 2021-02-09
14 Heights Capital Management, Inc. 183.5K 5.00% 183.5K 183.5K CO Delaware 2020-02-10
15 Inc. 181.4K 4.90% 181.4K 181.4K FI, CO 2020-02-14
16 Kassam 181.4K 4.90% 181.4K 181.4K HC, IN 2020-02-14
17 LLC 181.4K 4.90% 181.4K 181.4K HC, OO 2020-02-14
18 Management LP 181.4K 4.90% 181.4K 181.4K IA, PN 2020-02-14
19 Nathoo 181.4K 4.90% 181.4K 181.4K HC, IN 2020-02-14
20 Winson 181.4K 4.90% 181.4K 181.4K HC, IN 2020-02-14
21 Martin D. Hoe 4.9K 5.25% 4.9K IN United States 2021-02-18
22 Ryan M. Lane 4.9K 5.25% 4.9K IN United States 2021-02-18
23 Altium Capital Management, LP 0.00% IA, PN Delaware, United States of America 2022-02-14
24 Altium Growth Fund, LP 0.00% PN Delaware, United States of America 2022-02-14
25 Altium Growth GP, LLC 0.00% OO Delaware, United States of America 2022-02-14

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 XTX TOPCO LTD -17.4K (-100.0%) -1.4K (-100.0%) 0.00% -0.612 pp 0.00% 0.000 pp USD 2 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 1 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Vanguard Extended Market ETF VXF 0.00% 9.37 0.05%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
5
Sells
0
Shares acquired
390.0K
Shares disposed
Cash buys
Cash sales
Net activity
+390,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-21 Stetz Gary S. Director / Officer P-Purchase A Common Stock, par value $0.0001 per share 1,250,000 0.04 50.0K 1,250,000 I
2026-04-21 Purcell Michael J. Director P-Purchase A Common Stock, par value $0.0001 per share 1,250,000 0.04 50.0K 1,250,000 D
2026-04-21 LoPriore Vincent S Director / Officer / 10% Owner P-Purchase A Common Stock, par value $0.0001 per share 1,250,000 0.04 50.0K 6,250,000 I
2026-04-21 Appajosyula Sireesh Director P-Purchase A Common Stock, par value $0.0001 per share 1,250,000 0.04 50.0K 1,250,000 D
2026-03-16 Stetz Gary S. Director / Officer 0 0.00 0
2026-03-16 LoPriore Vincent S Director / Officer 0 0.00 0
2026-03-16 Appajosyula Sireesh Director 0 0.00 0
2024-03-06 Purcell Michael J. Director A-Award A Restricted Stock Units 50,000 0.00 50,000
2024-03-05 Purcell Michael J. Director 0 0.00 0
2024-02-19 Lbiati Kaouthar Director A-Award A Stock Options 85,000 2.56 217.6K 88,000
2024-02-19 JACOB GARY S Director A-Award A Stock Options 85,000 2.56 217.6K 102,120
2024-02-19 Block Timothy M. Director A-Award A Stock Options 85,000 2.56 217.6K 99,562
2024-02-19 BRANCACCIO JOHN P Director / Officer A-Award A Stock Options 85,000 2.56 217.6K 99,563
2023-11-27 Wijngaard Peter Director P-Purchase A Common Stock 2,500 3.05 7.6K 9,501
2023-11-24 Wijngaard Peter Director P-Purchase A Common Stock 2,500 3.09 7.7K 7,001
2023-09-19 Wijngaard Peter Director P-Purchase A Common Stock 1,000 5.64 5.6K 4,501
2023-09-18 Foster Robert T Director / Officer P-Purchase A Common Stock 1,600 5.60 9.0K 50,470
2023-09-15 Wijngaard Peter Director P-Purchase A Common Stock 861 5.37 4.6K 3,501
2023-09-15 Foster Robert T Director / Officer P-Purchase A Common Stock 1,600 5.40 8.6K 48,870
2022-06-27 Reddi Anand Director D Stock Options 60,000 0.69 41.4K 0
2022-06-27 Lbiati Kaouthar Director D Stock Options 60,000 0.69 41.4K 0
2021-05-18 Wijngaard Peter Director A-Award A Stock Options 200,000 1.70 340.0K 260,000
2021-05-18 Lippa Arnold Director A-Award A Stock Options 200,000 1.70 340.0K 291,110
2021-05-18 JACOB GARY S Director A-Award A Stock Options 250,000 1.70 425.0K 342,785
2021-05-18 Foster Robert T Director / Officer A-Award A Stock Options 1,900,000 1.70 3.23M 2,501,879
2021-05-18 Cavan John T Officer A-Award A Stock Options 1,200,000 1.70 2.04M 1,581,060
2021-05-18 Block Timothy M. Director A-Award A Stock Options 200,000 1.70 340.0K 291,276
2021-05-18 BRANCACCIO JOHN P Director A-Award A Stock Options 200,000 1.70 340.0K 291,332
2021-05-18 ADAMS THOMAS PHD Director A-Award A Stock Options 200,000 1.70 340.0K 291,050
2021-02-18 Foster Robert T Director / Officer P-Purchase A Common Stock 20,000 2.00 40.0K 45,259
2021-02-18 Cavan John T Officer P-Purchase A Common Stock 10,000 2.00 20.0K 14,800
2021-02-16 Wijngaard Peter Director P-Purchase A Common Stock 10,000 2.20 22.0K 30,000
2020-12-18 Wijngaard Peter Director P-Purchase A Common Stock 20,000 1.91 38.2K 20,000
2020-12-08 Foster Robert T Director / Officer P-Purchase A Common Stock 25,000 1.58 39.4K 25,259
2020-12-02 BRANCACCIO JOHN P Director P-Purchase A Common Stock 7,000 1.53 10.7K 7,008
2020-12-01 JACOB GARY S Director P-Purchase A Common Stock 12,000 1.66 19.9K 12,059
2020-11-25 Cavan John T Officer P-Purchase A Common Stock 4,500 1.62 7.3K 4,800
2020-08-19 Wijngaard Peter Director A-Award A Stock Options 30,000 3.72 111.6K 60,000
2020-08-19 Lippa Arnold Director A-Award A Stock Options 30,000 3.72 111.6K 91,110
2020-08-19 JACOB GARY S Director A-Award A Stock Options 30,000 3.72 111.6K 92,785
2020-08-19 Foster Robert T Director / Officer A-Award A Stock Options 212,000 3.72 788.6K 601,879
2020-08-19 Cavan John T Officer A-Award A Stock Options 160,000 3.72 595.2K 381,060
2020-08-19 Block Timothy M. Director A-Award A Stock Options 30,000 3.72 111.6K 91,276
2020-08-19 BRANCACCIO JOHN P Director A-Award A Stock Options 30,000 3.72 111.6K 91,332
2020-08-19 ADAMS THOMAS PHD Director A-Award A Stock Options 30,000 3.72 111.6K 91,050
2020-06-25 Wijngaard Peter Director A-Award A Stock Options 30,000 2.73 81.9K 30,000
2020-06-10 Wijngaard Peter Director 0 0.00 0
2020-04-03 Lippa Arnold Director A-Award A Stock Options 60,000 1.63 97.8K 61,109
2020-04-03 JACOB GARY S Director A-Award A Stock Options 60,000 1.63 97.8K 62,729
2020-04-03 Foster Robert T Director / Officer A-Award A Stock Options 380,000 1.63 619.4K 389,879
2020-04-03 Cavan John T Officer A-Award A Stock Options 215,000 1.63 350.5K 221,059
2020-04-03 Block Timothy M. Director A-Award A Stock Options 60,000 1.63 97.8K 61,220
2020-04-03 BRANCACCIO JOHN P Director A-Award A Stock Options 60,000 1.63 97.8K 61,275
2020-04-03 ADAMS THOMAS PHD Director A-Award A Stock Option 60,000 1.63 97.8K 61,051
2019-07-24 Lippa Arnold Director A-Award A Stock Options 970 3.24 3.1K 1,109
2019-07-24 JACOB GARY S Director A-Award A Stock Options 970 3.24 3.1K 2,729
2019-07-24 Foster Robert T Director / Officer A-Award A Stock Options 9,700 3.24 31.4K 9,879
2019-07-24 Cavan John T Officer A-Award A Stock Options 5,820 3.24 18.9K 6,059
2019-07-24 Block Timothy M. Director A-Award A Stock Options 970 3.24 3.1K 1,220
2019-07-24 BRANCACCIO JOHN P Director A-Award A Stock Options 970 3.24 3.1K 1,275
2019-07-24 ADAMS THOMAS PHD Director A-Award A Stock Options 970 3.24 3.1K 1,051
2019-03-15 Garlikov Donald E 10% Owner D Common Stock 0 0.00 3,320,000
2018-07-03 Lippa Arnold Director P-Purchase A Series C Convertible Preferred Stock 15 1.55 23.25 15
2018-07-03 JACOB GARY S Director P-Purchase A Warrants 8,625 1.55 13.4K 8,625
2018-07-03 Cavan John T Officer P-Purchase A Warrants 8,625 1.55 13.4K 8,625
2018-07-03 BRANCACCIO JOHN P Director P-Purchase A Warrants 1,725 1.55 2.7K 1,725
2018-01-03 SAPIRSTEIN JAMES Director / Officer A-Award A Common Stock 322,092 0.00 492,819
2018-01-03 Foster Robert T Officer A-Award A Common Stock 100,654 0.00 144,736
2018-01-03 Cavan John T Officer A-Award A Common Stock 101,221 0.00 167,947
2017-07-20 Cavan John T Officer A-Award A Stock Options 15,000 0.58 8.7K 133,688
2017-07-06 Sullivan-Bolyai John Z Officer A-Award A Common Stock 58,681 0.00 58,681
2017-07-06 SAPIRSTEIN JAMES Director / Officer A-Award A Common Stock 141,061 0.00 170,727
2017-07-06 Foster Robert T Officer A-Award A Common Stock 44,082 0.00 44,082
2017-07-06 Cavan John T Officer A-Award A Common Stock 46,726 0.00 66,726
2017-06-20 Cavan John T Officer P-Purchase A Common Stock 20,000 0.65 13.0K 20,000
2017-04-28 Garlikov Donald E 10% Owner D Warrants 31,250 10.00 312.5K 0
2017-04-10 HOWSON TAMAR D Director A-Award A Stock Options 35,000 1.60 56.0K 80,000
2017-03-06 SAPIRSTEIN JAMES Director / Officer A-Award A Stock Options 313,898 1.48 464.6K 2,761,129
2017-03-03 SAPIRSTEIN JAMES Director / Officer A-Award A Stock Options 313,898 1.43 448.9K 2,447,231
2016-12-14 HOWSON TAMAR D Director D Stock Options 45,000 2.01 90.5K 0
2016-10-27 SAPIRSTEIN JAMES Director / Officer M-Exempt D Stock Options 16,666 1.50 25.0K 2,133,334
2016-09-20 ADAMS THOMAS PHD Director D Stock Options 45,000 1.12 50.4K 0
2016-08-26 Sullivan-Bolyai John Z Officer A-Award A Stock Options 135,790 1.10 149.4K 290,790
2016-08-26 Cavan John T Officer A-Award A Stock Options 18,688 1.10 20.6K 118,688
2016-08-17 CERRONE GABRIEL 10% Owner D Common Stock 0 0.00 78,146
2016-07-19 Lippa Arnold Director A-Award A Stock Options 32,500 1.04 33.8K 77,500
2016-07-19 JACOB GARY S Director A-Award A Stock Options 65,000 1.04 67.6K 1,015,000
2016-07-19 Block Timothy M. Director A-Award A Stock Options 65,000 1.04 67.6K 169,688
2016-07-19 BRANCACCIO JOHN P Director A-Award A Stock Options 65,000 1.04 67.6K 200,656
2016-06-13 Sullivan-Bolyai John Z Officer A-Award A Stock Options 20,000 0.99 19.8K 155,000
2016-06-13 SAPIRSTEIN JAMES Director / Officer A-Award A Stock Options 500,000 0.99 495.0K 2,150,000
2016-06-10 Foster Robert T Officer D Stock Options 100,000 0.92 92.0K 0
2016-04-04 Garlikov Donald E 10% Owner I Warrants 31,250 13.60 425.0K 0
2016-04-01 Cavan John T Officer D Stock Options 100,000 1.21 121.0K 0
2016-03-02 Sullivan-Bolyai John Z Officer D Stock Options 135,000 2.56 345.6K 0
2016-02-18 SAPIRSTEIN JAMES Director / Officer P-Purchase A Common Stock 10,000 1.00 10.0K 13,000
2015-11-30 SAPIRSTEIN JAMES Director / Officer P-Purchase A Common Stock 500 2.15 1.1K 3,000
2015-11-30 Lippa Arnold Director D Stock Options 45,000 2.16 97.2K 0
2015-11-23 SAPIRSTEIN JAMES Director / Officer P-Purchase A Common Stock 2,500 1.64 4.1K 2,500
2015-10-13 Garlikov Donald E 10% Owner D Warrants 31,250 34.00 1.06M 0
2015-06-04 SAPIRSTEIN JAMES Director / Officer A-Award A Stock Options 150,000 3.60 540.0K 1,650,000
2015-06-04 Hornung William Karl Officer A-Award A Stock Options 15,000 3.60 54.0K 165,000
2014-12-03 SAPIRSTEIN JAMES Director / Officer A-Award A Stock Options 500,000 1.50 750.0K 1,500,000
2014-12-03 McGuigan Christopher Director A-Award A Stock Options 118,638 1.50 178.0K 415,234
2014-12-03 JACOB GARY S Director A-Award A Stock Options 420,000 1.50 630.0K 950,000
2014-12-03 Hornung William Karl Officer A-Award A Stock Options 50,000 1.50 75.0K 150,000
2014-12-03 Block Timothy M. Director A-Award A Stock Options 29,911 1.50 44.9K 104,688
2014-12-03 BRANCACCIO JOHN P Director A-Award A Stock Options 38,759 1.50 58.1K 135,656
2014-06-23 Hornung William Karl Officer D Stock Options 100,000 1.70 170.0K 0
2014-04-03 Denoyer Bernard Officer A-Award A Stock Options 20,000 2.35 47.0K 40,000
2014-04-03 Block Timothy M. Director A-Award A Stock Options 15,000 2.35 35.3K 74,777
2014-04-03 BRANCACCIO JOHN P Director A-Award A Stock Options 15,000 2.35 35.3K 96,897
2014-03-19 SAPIRSTEIN JAMES Director / Officer D Stock Options 1,000,000 2.31 2.31M 0
2014-03-19 JACOB GARY S Director A-Award A Stock Options 300,000 2.31 693.0K 530,000
2014-03-12 McGuigan Christopher Director A-Award A Stock Options 16,596 2.37 39.3K 296,596
2014-03-12 Block Timothy M. Director A-Award A Stock Options 19,777 2.37 46.9K 59,777
2014-03-12 BRANCACCIO JOHN P Director A-Award A Stock Options 21,897 2.37 51.9K 81,897
2014-03-04 BRANCACCIO JOHN P Director P-Purchase A Common Stock, par value $0.0001 per share 4,393 1.49 6.5K 6,408
2014-02-18 SYNERGY PHARMACEUTICALS, INC. 10% Owner J-Other D Common Stock, par value $0.0001 per share 9,000,000 0.00 0
2014-02-18 JACOB GARY S Director / Officer J-Other A Common Stock, par value $0.0001 per share 32,935 0.00 32,935
2014-02-18 Denoyer Bernard Officer J-Other A Common Stock, par value $0.0001 per share 1,030 0.00 1,030
2014-02-18 BRANCACCIO JOHN P Director J-Other A Common Stock, par value $0.0001 per share 2,015 0.00 2,015
2014-01-24 McGuigan Christopher Director A-Award A Stock Options 250,000 0.37 92.5K 280,000
2014-01-24 JACOB GARY S Director / Officer A-Award A Stock Options 200,000 0.37 74.0K 230,000
2014-01-24 Denoyer Bernard Director A-Award A Stock Options 10,000 0.37 3.7K 20,000
2014-01-24 Block Timothy M. Director A-Award A Stock Options 10,000 0.37 3.7K 40,000
2014-01-24 BRANCACCIO JOHN P Director A-Award A Stock Options 30,000 0.37 11.1K 60,000
2013-11-26 Denoyer Bernard Officer A-Award A Stock Options 10,000 0.11 1.1K 10,000
2013-11-26 Block Timothy M. Director D Stock Options 30,000 0.11 3.3K 0
2013-10-07 SYNERGY PHARMACEUTICALS, INC. 10% Owner D Common Stock, par value $0.0001 per share 0 0.00 9,000,000
2013-10-07 Denoyer Bernard Officer 0 0.00 0
2013-10-02 McGuigan Christopher Director D Stock Options 30,000 0.11 3.3K 0
2013-10-02 JACOB GARY S Director / Officer D Stock Options 30,000 0.11 3.3K 0
2013-10-02 BRANCACCIO JOHN P Director D Stock Options 30,000 0.11 3.3K 0

Executive team

Top executives
Shares Outstanding
11.62M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 John Brancaccio Former Interim Chief Executive Officer and Chief Financial Officer 232.5K 232.5K 0.00%
2 2025 Kaouthar Lbiati, M.D. Former Chief Executive Officer 198.0K 198.0K 0.00%
3 2024 John Brancaccio Former Interim Chief Executive Officer and Chief Financial Officer 313.9K 188.4K 502.3K 37.51%
4 2014 James Sapirstein Chief Executive Officer 86.2K 1.26M 0.00%
5 2014 Gary S. Jacob, Ph.D. Chairman of the Board and former Chief Executive Officer 274.2K 0.00%
6 2014 William Hornung Chief Financial Officer 4.9K 80.2K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-28 DEF 14A
2025-04-16 PRE 14A
2025-02-07 DEF 14A
2025-01-27 PRE 14A
2024-12-05 DEFA14A
2024-12-02 DEFA14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-01 SC 13D
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS
2026-04-27 4
2026-04-27 4
2026-04-27 4
2026-04-27 4
2026-04-22 D
2026-04-22 8-K

Executive team

NameTitleCompensationGender
Gary S. Stetz Interim Chief Executive Officer & Director 85.5K male
Kaouthar Lbiati CEO & Director 85.5K
Sharen Pyatetskaya Director of Investor Relations
Vincent LoPriore Executive Chairman male
ESG Rating
B-
BIOTECHNOLOGY
Rank: 699 out of 710
2025
E (Environmental)
48.1 / 56.3
Company / Sector avg.
S (Social)
55.9 / 62.4
Company / Sector avg.
G (Governance)
57.4 / 60.9
Company / Sector avg.
ESG Total
53.8 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits