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Gyre Therapeutics, Inc. (GYRE)

US NASDAQ Healthcare Biotechnology
Address 12770 High Bluff Drive 92130
San Diego, CA, US
CEO Ping Zhang
Website gyretx.com
IPO 2006-04-12
CIK 1124105 ISIN US4037831033

Explore sections of this company profile

Description

Gyre Therapeutics, Inc. is a pharmaceutical company dedicated to discovering, advancing, and bringing to market small-molecule drugs that target inflammation and fibrosis in various organs. The company's key anti-fibrotic medication, ETUARY (Pirfenidone), has received approval for treating idiopathic pulmonary fibrosis. Beyond this, ETUARY is also undergoing late-stage (Phase 3) clinical trials for several other conditions, including dermatomyositis and interstitial lung disease linked to systemic sclerosis, pneumoconiosis, and diabetic kidney disease. The company's pipeline further includes F351 (Hydronidone), a compound structurally related to ETUARY. F351 is currently in Phase 3 studies for chronic hepatitis B-induced liver fibrosis and is in Phase 1 trials for liver fibrosis associated with nonalcoholic associated steatohepatitis (NASH). Other programs in development feature F573, which is progressing through Phase 2 studies for acute and acute-on-chronic liver failure. Additionally, two early-stage candidates, F528 and F230, are in preclinical development, focusing on chronic obstructive pulmonary disease (COPD) and pulmonary arterial hypertension (PAH), respectively. Established in 2002, Gyre Therapeutics, Inc. is based in San Diego, California, and operates as a subsidiary of GNI USA, Inc.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
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Volume Profile
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Liquidity & share structure
Average Volume
91.6K
Beta
4.78
Float Shares
17.32M
Free Float %
17.9%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+2.96% -7.59% -1.22% -6.65% -12.47% +3.40% -32.59% +121.21% -88.73% -97.75% -99.95%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (1 ratings, all time) Buy
Price Targets & DCF
Current price
7.02
Low 16.00 +128.1%
Consensus 17.00 +142.3%
Median 17.00 +142.3%
High 18.00 +156.6%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 3 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 2
17.00
All Time 2
17.00
Quality scores
Altman Z-Score
17.57
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +10.2% Q1'26: +2.1% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -55.0% Q1'26: -2,425.6% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -6.3% Q1'26: +13.3% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    +9.9% Q1'26: -41.5% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    +8.7% Q1'26: -34.8% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +0.9% Q1'26: -10.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.07× Q1'26: -0.02× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (5.28) × ERP
WACC = 100% × Ke + 0% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 6.25
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
2 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
399.0K
est: 432.0K (-7.6%)
1.02M
est: 811.0K (+25.5%)
6.0K
est: 528.0K (-98.9%)
est: 15.00M (-100.0%)
20.95M
est: 18.97M (+10.4%)
7.34M
est: 5.07M (+44.8%)
102.29M
est: 1.00M (+10,129.0%)
113.45M
est: 113.45M (+0.0%)
105.76M
est: 101.39M (+4.3%)
116.59M
est: 114.83M (+1.5%)
135.33M
117.57M – 160.46M
+17.9% YoY
130.75M
113.59M – 155.02M
-3.4% YoY
433.50M
431.65M – 435.35M
+231.5% YoY
262.30M
227.87M – 311.00M
-39.5% YoY
306.50M
266.27M – 363.40M
+16.9% YoY
EBITDA
-16.95M
est: -134.0K (-12,542.1%)
-21.82M
est: -251.6K (-8,572.3%)
-33.82M
est: -163.8K (-20,545.6%)
-55.03M
est: -4.65M (-1,082.5%)
-56.10M
est: -5.89M (-853.1%)
-87.64M
est: -1.57M (-5,475.1%)
10.33M
est: -310.3K (+3,430.0%)
20.33M
est: -35.20M (+157.7%)
17.82M
est: -8.74M (+303.8%)
14.01M
est: -9.90M (+241.5%)
-11.67M
-13.84M – -10.14M
-17.9% YoY
-11.28M
-13.37M – -9.80M
+3.4% YoY
-37.38M
-37.54M – -37.22M
-231.5% YoY
-22.62M
-26.82M – -19.65M
+39.5% YoY
-26.43M
-31.34M – -22.96M
-16.9% YoY
EBIT
-16.95M
est: -137.1K (-12,256.3%)
-21.56M
est: -257.4K (-8,274.9%)
-30.06M
est: -167.6K (-17,831.5%)
-55.18M
est: -4.76M (-1,058.8%)
-56.24M
est: -6.02M (-833.8%)
-87.93M
est: -1.61M (-5,367.2%)
9.20M
est: -317.4K (+2,999.1%)
19.21M
est: -36.01M (+153.3%)
16.23M
est: -9.91M (+263.8%)
11.49M
est: -11.22M (+202.4%)
-13.23M
-15.68M – -11.49M
-17.9% YoY
-12.78M
-15.15M – -11.10M
+3.4% YoY
-42.37M
-42.55M – -42.19M
-231.5% YoY
-25.64M
-30.39M – -22.27M
+39.5% YoY
-29.95M
-35.52M – -26.02M
-16.9% YoY
Net Income
-16.95M
est: -34.87B (+100.0%)
-21.56M
est: -12.13B (+99.8%)
-30.06M
est: -3.86B (+99.2%)
-55.18M
est: -5.05B (+98.9%)
-55.54M
est: -4.14B (+98.7%)
-87.93M
est: -4.31B (+98.0%)
2.30M
est: 1.41B (-99.8%)
-92.93M
est: -245.50M (+62.1%)
12.09M
est: 17.54M (-31.1%)
5.03M
est: 16.85M (-70.2%)
-26.70M
-35.86M – -23.96M
-258.4% YoY
-10.68M
-12.81M – -8.56M
+60.0% YoY
187.00M
161.73M – 242.08M
+1,850.4% YoY
26.83M
22.25M – 33.30M
-85.7% YoY
35.08M
29.09M – 43.55M
+30.8% YoY
SGA
9.26M
est: 466.7K (+1,884.6%)
9.99M
est: 876.1K (+1,040.6%)
12.35M
est: 570.4K (+2,065.8%)
13.27M
est: 16.20M (-18.1%)
16.18M
est: 20.50M (-21.1%)
18.82M
est: 5.47M (+243.8%)
71.61M
est: 1.08M (+6,528.4%)
75.82M
est: 122.56M (-38.1%)
73.62M
est: 108.82M (-32.3%)
85.98M
est: 123.26M (-30.2%)
145.26M
126.19M – 172.23M
+17.9% YoY
140.34M
121.92M – 166.39M
-3.4% YoY
465.29M
463.31M – 467.28M
+231.5% YoY
281.54M
244.58M – 333.81M
-39.5% YoY
328.98M
285.80M – 390.06M
+16.9% YoY
EPS
-21.76
est: -340.88 (+93.6%)
-6.30
est: -118.60 (+94.7%)
-2.68
est: -37.73 (+92.9%)
-4.41
est: -49.35 (+91.1%)
-2.93
est: -40.46 (+92.8%)
-2.87
est: -42.11 (+93.2%)
0.03
est: 13.80 (-99.8%)
-1.41
est: -2.40 (+41.3%)
0.14
est: 0.17 (-17.6%)
0.06
est: 0.16 (-65.5%)
-0.28
-0.35 – -0.23
-271.4% YoY
-0.10
-0.12 – -0.08
+64.3% YoY
1.89
1.57 – 2.35
+1,990.0% YoY
0.26
0.22 – 0.32
-86.2% YoY
0.34
0.28 – 0.42
+30.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-06 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-05-05 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-05-04 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-05-01 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-04-30 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-04-29 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-04-28 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-04-27 C+ 2/5 1/5 2/5 4/5 3/5 1/5 1/5
2026-04-24 C+ 2/5 1/5 3/5 4/5 3/5 1/5 1/5
2026-04-23 C+ 2/5 1/5 3/5 4/5 2/5 1/5 1/5
2026-04-22 C+ 2/5 1/5 3/5 4/5 2/5 1/5 1/5
2026-04-21 C+ 2/5 1/5 3/5 5/5 2/5 1/5 1/5
2026-04-20 C+ 2/5 1/5 3/5 5/5 2/5 1/5 1/5
2026-04-17 C+ 2/5 1/5 3/5 5/5 2/5 1/5 1/5
2026-04-16 C+ 2/5 1/5 3/5 5/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
1.42M
OE per share TTM
0.05
Owner's Yield
0.22%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
21.6%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
10
Total invested
1.39M
Insider transactions (90d)
6
Beneficial owners (>5%)
4
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Ping Lan 8.46M 8.54% 8.46M 10.00 IN 2024-09-06
2 Ying Luo (“Mr. Luo”) 8.46M 8.54% 8.46M 10.00 IN 2024-09-06
3 Songjiang Ma (“Mr. Ma”) 7.46M 7.62% 7.46M 7.46M IN 2024-09-06
4 Yueying Zhu 7.46M 7.62% 7.46M 7.46M IN 2024-09-06

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
10
-33 vs prev Q
New positions
3
Closed positions
36
Increased
4
Reduced
0
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 VANGUARD GROUP INC 1.20M +51.0K (+4.4%) 8.48M -100.0K (-1.2%) 1.35% +0.057 pp 0.00% +0.000 pp USD10.98 -35.7% 9 qtrs
2 BLACKROCK, INC. 720.3K +60.9K (+9.2%) 5.09M +166.2K (+3.4%) 0.81% +0.068 pp 0.00% +0.000 pp USD10.32 -31.6% 6 qtrs
3 GEODE CAPITAL MANAGEMENT, LLC 423.2K +48.6K (+13.0%) 2.99M +193.7K (+6.9%) 0.47% +0.055 pp 0.00% +0.000 pp USD14.78 -52.2% 9 qtrs
4 STATE STREET CORP 202.2K +19.5K (+10.7%) 1.43M +64.4K (+4.7%) 0.23% +0.022 pp 0.00% +0.000 pp USD11.75 -39.9% 9 qtrs
5 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 169.2K +45.8K (+37.1%) 1.19M +273.8K (+29.7%) 0.19% +0.051 pp 0.00% +0.000 pp USD10.47 -32.6% 7 qtrs
6 SBI SECURITIES CO., LTD. 162.9K -5.0K (-2.9%) 1.15M -102.1K (-8.2%) 0.18% -0.006 pp 0.03% -0.003 pp USD9.46 -25.4% 5 qtrs
7 NORTHERN TRUST CORP 128.9K +12.5K (+10.8%) 909.7K +41.8K (+4.8%) 0.14% +0.014 pp 0.00% +0.000 pp USD12.66 -44.2% 9 qtrs
8 MORGAN STANLEY 54.5K +45.5K (+506.8%) 384.8K +317.8K (+474.3%) 0.06% +0.051 pp 0.00% +0.000 pp USD7.51 -6.0% 8 qtrs
9 BANK OF NEW YORK MELLON CORP 41.2K +16.8K (+68.9%) 290.9K +108.9K (+59.8%) 0.05% +0.019 pp 0.00% +0.000 pp USD8.84 -20.1% 7 qtrs
10 GOLDMAN SACHS GROUP INC 31.1K +13.1K (+72.5%) 219.6K +85.1K (+63.2%) 0.03% +0.015 pp 0.00% +0.000 pp USD7.29 -3.2% 8 qtrs
11 STATE OF WISCONSIN INVESTMENT BOARD 24.8K -14.2K (-36.4%) 175.1K -115.9K (-39.8%) 0.03% -0.016 pp 0.00% 0.000 pp USD7.35 -3.9% 3 qtrs
12 ALLIANCEBERNSTEIN L.P. 21.8K +— (+0.0%) 154.1K -8.7K (-5.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD7.36 -4.1% 3 qtrs
13 STRS OHIO 21.1K +— (+0.0%) 149.0K -8.4K (-5.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD7.39 -4.5% 3 qtrs
14 BARCLAYS PLC 18.5K +9.2K (+99.5%) 130.8K +14.4K (+12.3%) 0.02% +0.010 pp 0.00% +0.000 pp USD8.09 -12.7% 7 qtrs
15 RHUMBLINE ADVISERS 14.0K +600.0 (+4.5%) 99.1K -1.1K (-1.1%) 0.02% +0.001 pp 0.00% +0.000 pp USD10.25 -31.1% 7 qtrs
16 WELLS FARGO & COMPANY/MN 12.9K +7.4K (+132.4%) 91.2K +49.7K (+120.0%) 0.01% +0.008 pp 0.00% +0.000 pp USD8.43 -16.3% 9 qtrs
17 ROYAL BANK OF CANADA 12.8K +370.0 (+3.0%) 91.0K -1.0K (-1.1%) 0.01% +0.000 pp 0.00% +0.000 pp USD7.54 -6.4% 7 qtrs
18 DIMENSIONAL FUND ADVISORS LP 10.9K +10.9K (+100.0%) 77.0K +77.0K (+100.0%) 0.01% +0.012 pp 0.00% +0.000 pp USD7.06 +0.0% 1 qtrs NEW
19 DEUTSCHE BANK AG\ 10.6K -314.0 (-2.9%) 74.9K -6.6K (-8.1%) 0.01% 0.000 pp 0.00% +0.000 pp USD7.35 -3.9% 3 qtrs
20 FMR LLC 10.3K +100.0 (+1.0%) 72.7K -3.4K (-4.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD7.52 -6.1% 6 qtrs
21 JANE STREET GROUP, LLC 10.0K +10.0K (+100.0%) 70.6K +70.6K (+100.0%) 0.01% +0.011 pp 0.00% +0.000 pp USD7.06 +0.0% 1 qtrs NEW
22 BANK OF AMERICA CORP /DE/ 9.8K +3.1K (+45.9%) 68.9K +19.0K (+38.1%) 0.01% +0.003 pp 0.00% +0.000 pp USD9.61 -26.5% 7 qtrs
23 UBS GROUP AG 9.6K -13.4K (-58.3%) 67.7K -103.6K (-60.5%) 0.01% -0.015 pp 0.00% +0.000 pp USD9.21 -23.3% 9 qtrs
24 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 5.5K +1.3K (+30.4%) 38.7K +7.3K (+23.4%) 0.01% +0.001 pp 0.00% +0.000 pp USD9.44 -25.2% 6 qtrs
25 JPMORGAN CHASE & CO 5.1K +1.4K (+38.4%) 36.1K +8.5K (+31.0%) 0.01% +0.002 pp 0.00% +0.000 pp USD10.31 -31.5% 9 qtrs
26 STATE OF ALASKA, DEPARTMENT OF REVENUE 5.2K +— (+0.0%) 36.0K -2.0K (-5.3%) 0.01% +0.000 pp 0.00% +0.000 pp USD7.46 -5.4% 2 qtrs
27 NEW YORK STATE COMMON RETIREMENT FUND 2.7K +— (+0.0%) 19.1K -1.1K (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD12.04 -41.4% 7 qtrs
28 BNP PARIBAS ARBITRAGE, SNC 2.6K +388.0 (+17.9%) 18.0K +1.9K (+11.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD8.52 -17.1% 8 qtrs
29 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 2.1K +— (+0.0%) 14.8K -839.0 (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD7.72 -8.5% 4 qtrs
30 TOWER RESEARCH CAPITAL LLC (TRC) 2.1K -617.0 (-22.9%) 14.7K -5.4K (-27.0%) 0.00% -0.001 pp 0.00% 0.000 pp USD9.56 -26.2% 9 qtrs
31 RUSSELL INVESTMENTS GROUP, LTD. 2.0K +879.0 (+78.2%) 14.1K +5.8K (+68.6%) 0.00% +0.001 pp 0.00% +0.000 pp USD7.28 -3.0% 2 qtrs
32 LEGAL & GENERAL GROUP PLC 1.4K +545.0 (+63.4%) 9.9K +3.5K (+53.7%) 0.00% +0.001 pp 0.00% +0.000 pp USD8.38 -15.8% 7 qtrs
33 SIMPLEX TRADING, LLC 839.00 +675.0 (+411.6%) 5.9K +4.9K (+492.3%) 0.00% +0.001 pp 0.00% +0.000 pp USD7.14 -1.1% 2 qtrs
34 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 726.00 -122.0 (-14.4%) 5.1K -1.2K (-19.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD10.14 -30.4% 7 qtrs
35 AMERITAS INVESTMENT PARTNERS, INC. 683.00 +— (+0.0%) 4.8K -273.0 (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD12.04 -41.4% 7 qtrs
36 ACTIVEST WEALTH MANAGEMENT 533.00 +— (+0.0%) 3.8K -213.0 (-5.4%) 0.00% +0.000 pp 0.00% 0.000 pp USD12.04 -41.4% 7 qtrs
37 AMALGAMATED BANK 371.00 +130.0 (+53.9%) 3.0K +1.0K (+50.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD10.29 -31.4% 7 qtrs
38 CITIGROUP INC 268.00 -116.0 (-30.2%) 1.9K -972.0 (-33.9%) 0.00% 0.000 pp 0.00% +0.000 pp USD13.83 -49.0% 9 qtrs
39 OPTIVER HOLDING B.V. 222.00 +— (+0.0%) 1.6K -89.0 (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD7.46 -5.4% 2 qtrs
40 NISA INVESTMENT ADVISORS, LLC 102.00 +— (+0.0%) 720.00 -41.0 (-5.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD10.37 -31.9% 6 qtrs
41 STERLING CAPITAL MANAGEMENT LLC 59.00 +37.0 (+168.2%) 417.00 +253.0 (+154.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD8.93 -20.9% 6 qtrs
42 ADVISOR GROUP HOLDINGS, INC. 38.00 +— (+0.0%) 268.00 -15.0 (-5.3%) 0.00% +0.000 pp 0.00% +0.000 pp USD8.76 -19.4% 9 qtrs
43 SMARTLEAF ASSET MANAGEMENT LLC 6.00 +6.0 (+100.0%) 42.00 +42.0 (+100.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD7.00 +0.9% 1 qtrs NEW
44 PRINCIPAL SECURITIES, INC. -85.0 (-100.0%) -634.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 3 qtrs SOLD
45 SRS CAPITAL ADVISORS, INC. -57.0 (-100.0%) -426.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
46 LAZARD ASSET MANAGEMENT LLC -14.9K (-100.0%) -111.4K (-100.0%) 0.00% -0.017 pp 0.00% 0.000 pp USD 4 qtrs SOLD
47 MILLENNIUM MANAGEMENT LLC -35.8K (-100.0%) -266.7K (-100.0%) 0.00% -0.040 pp 0.00% 0.000 pp USD 2 qtrs SOLD
48 ADVISORY SERVICES NETWORK, LLC -66.0 (-100.0%) -492.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 43 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 WisdomTree U.S. SmallCap Fund EES 0.02% 148.5K 0.38%
2 iShares Russell 2000 Growth ETF IWO 0.01% 789.2K 0.24%
3 Vanguard Russell 2000 Growth ETF VTWG 0.00% 64.9K 0.06%
4 Invesco Russell 2000 UCITS ETF RTYS.L 0.00% 12.2K 0.25%
5 Global X - Russell 2000 ETF RSSL 0.00% 56.0K 0.08%
6 Xtrackers Russell 2000 UCITS ETF 1C XRSU.L 0.00% 107.4K 0.30%
7 iShares Russell 2000 BuyWrite ETF IWMW 0.00% 1.8K 0.39%
8 iShares Russell 2000 ETF IWM 0.00% 2.62M 0.19%
9 iShares U.S. Small Cap Index ETF (CAD-Hedged) XSU.TO 0.00% 17.1K 0.36%
10 Schwab U.S. Small-Cap ETF SCHA 0.00% 649.6K 0.03%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
9
Sells
0
Shares acquired
3.01M
Shares disposed
Cash buys
Cash sales
Net activity
+3,010,583
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-04 Xiong Yue Officer Series B Preferred Stock 2,376,500 0.00 0 D
2026-05-04 Wang Jialiang (NMN) Officer Stock Option (Right to Buy) 42,777 2.00 85.6K 0 D
2026-05-04 Luo Ying Director / Officer Stock Option (Right to Buy) 988,624 2.00 1.98M 0 D
2026-05-04 GNI Group Ltd. 10% Owner J-Other A Series B Preferred Stock 458,120 0.00 458,120 I
2026-05-04 Eastling Thomas Wilson Officer A-Award A Stock Option (Right to Buy) 11,882 2.00 23.8K 11,882 D
2026-05-04 Bergmann Joshua Benjamin Officer Stock Option (Right to Buy) 47,530 8.09 384.5K 0 D
2026-01-07 Zhang Ping Director A-Award A Stock Option (Right to Buy) 100,000 7.31 731.0K 100,000 D
2026-01-07 Chen Ruoyu Officer A-Award A Stock Option (Right to Buy) 50,000 7.31 365.5K 50,000 D
2025-08-18 Weng Dan 0 0.00 0
2025-08-05 Zhang Ping Director A-Award A Stock Option (Right to Buy) 250,000 6.92 1.73M 250,000 D
2025-06-04 Parry Renate Director A-Award A Stock Option (Right to Buy) 26,000 8.58 223.1K 26,000 D
2025-06-04 Nussbaum Rodney L Director A-Award A Stock Option (Right to Buy) 26,000 8.58 223.1K 26,000 D
2025-06-04 Epstein David M. Director A-Award A Stock Option (Right to Buy) 26,000 8.58 223.1K 26,000 D
2025-06-04 Eastling Thomas Wilson Director A-Award A Stock Option (Right to Buy) 26,000 8.58 223.1K 26,000 D
2025-06-04 Carmichael Gordon Director A-Award A Stock Option (Right to Buy) 26,000 8.58 223.1K 26,000 D
2025-05-28 Ma Songjiang Director / Officer S-Sale D Common Stock 558 10.07 5.6K 2,806,084 I
2025-05-27 Zhang Ping Director A-Award A Stock Option (Right to Buy) 250,000 10.18 2.55M 250,000 D
2025-05-27 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.28 20.6K 2,806,642 I
2025-05-23 Ma Songjiang Director / Officer S-Sale D Common Stock 182 10.24 1.9K 2,808,642 I
2025-05-22 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.97 21.9K 2,808,824 I
2025-05-21 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.83 21.7K 2,810,824 I
2025-05-20 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.25 22.5K 2,812,824 I
2025-05-19 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.11 22.2K 2,814,824 I
2025-05-16 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.31 22.6K 2,816,824 I
2025-05-15 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.68 21.4K 2,818,824 I
2025-05-14 Ma Songjiang Director / Officer S-Sale D Common Stock 20 11.30 226.00 2,820,824 I
2025-05-13 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.37 22.7K 2,820,844 I
2025-05-12 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.56 21.1K 2,822,844 I
2025-04-16 Eastling Thomas Wilson Director M-Exempt D Stock Option (Right to Buy) 15,000 6.93 104.0K 299,652 D
2025-04-01 Ye Weiguo Officer M-Exempt D Stock Option (Right to Buy) 50,000 0.75 37.5K 965,115 D
2025-03-27 Ye Weiguo Officer M-Exempt D Stock Option (Right to Buy) 150,000 0.75 112.5K 1,015,115 D
2025-03-26 Ye Weiguo Officer M-Exempt D Stock Option (Right to Buy) 200,000 0.75 150.0K 1,165,115 D
2025-03-24 Ye Weiguo Officer M-Exempt D Stock Option (Right to Buy) 300,000 0.75 225.0K 1,365,115 D
2025-03-21 Ma Songjiang Director / Officer S-Sale D Common Stock 174 10.00 1.7K 2,824,844 I
2025-03-20 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.09 20.2K 2,825,018 I
2025-03-19 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.13 20.3K 2,827,018 I
2025-03-18 Ma Songjiang Director / Officer S-Sale D Common Stock 242 10.24 2.5K 2,829,018 I
2025-03-17 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.09 24.2K 2,829,260 I
2025-03-14 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.31 24.6K 2,831,260 I
2025-03-13 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.80 23.6K 2,833,260 I
2025-03-12 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.74 23.5K 2,835,260 I
2025-03-11 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.40 22.8K 2,837,260 I
2025-03-10 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.14 20.3K 2,839,260 I
2025-03-07 Ye Weiguo Officer A-Award A Stock Option (Right to Buy) 300,000 10.32 3.10M 300,000 D
2025-03-07 Ma Songjiang Director / Officer S-Sale D Common Stock 1,906 10.13 19.3K 2,841,260 I
2025-03-06 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.80 21.6K 2,843,260 I
2025-03-05 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.98 22.0K 2,845,260 I
2025-03-04 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.86 21.7K 2,847,260 I
2025-03-03 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.23 22.5K 2,849,260 I
2025-02-28 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.41 22.8K 2,851,260 I
2025-02-27 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.33 22.7K 2,853,260 I
2025-02-26 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.63 23.3K 2,855,260 I
2025-02-25 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.37 22.7K 2,857,260 I
2025-02-24 Ma Songjiang Director / Officer S-Sale D Common Stock 187 11.52 2.2K 2,859,260 I
2025-02-21 Ma Songjiang Director / Officer S-Sale D Common Stock 182 12.60 2.3K 2,861,260 I
2025-02-20 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.40 24.8K 2,863,260 I
2025-02-19 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.29 24.6K 2,865,260 I
2025-02-18 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.49 25.0K 2,867,260 I
2025-02-14 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.94 23.9K 2,869,260 I
2025-02-13 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.69 23.4K 2,871,260 I
2025-02-12 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.49 23.0K 2,873,260 I
2025-02-11 Ma Songjiang Director / Officer S-Sale D Common Stock 1,878 11.52 21.6K 2,875,260 I
2025-02-10 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.90 23.8K 2,877,138 I
2025-02-07 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.16 24.3K 2,879,158 I
2025-02-06 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.85 25.7K 2,881,138 I
2025-02-05 Ma Songjiang Director / Officer S-Sale D Common Stock 1,980 12.39 24.5K 2,883,158 I
2025-02-04 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.62 23.2K 2,885,138 I
2025-02-03 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.47 22.9K 2,887,138 I
2025-01-31 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.51 23.0K 2,889,138 I
2025-01-30 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.37 22.7K 2,891,138 I
2025-01-29 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.43 22.9K 2,893,138 I
2025-01-28 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.51 23.0K 2,895,138 I
2025-01-27 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.18 22.4K 2,897,138 I
2025-01-24 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.89 21.8K 2,899,138 I
2025-01-23 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.49 21.0K 2,901,138 I
2025-01-22 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.63 21.3K 2,903,138 I
2025-01-21 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.85 21.7K 2,905,138 I
2025-01-17 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.72 21.4K 2,907,138 I
2025-01-16 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.71 21.4K 2,909,138 I
2025-01-15 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.85 21.7K 2,911,138 I
2025-01-14 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.39 20.8K 2,913,138 I
2025-01-13 Ma Songjiang Director / Officer S-Sale D Common Stock 56 10.10 565.60 2,915,138 I
2025-01-10 Ma Songjiang Director / Officer S-Sale D Common Stock 1,057 10.02 10.6K 2,915,194 I
2025-01-07 Ma Songjiang Director / Officer S-Sale D Common Stock 1,275 10.02 12.8K 2,916,251 I
2025-01-06 Ma Songjiang Director / Officer S-Sale D Common Stock 941 10.16 9.6K 2,917,526 I
2025-01-05 Zhang Ping Director A-Award A Stock Option (Right to Buy) 52,000 10.79 561.1K 52,000 D
2025-01-03 Ma Songjiang Director / Officer S-Sale D Common Stock 833 11.85 9.9K 2,918,467 I
2025-01-02 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.40 24.8K 2,920,467 I
2024-12-31 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.30 24.6K 2,922,467 I
2024-12-30 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.50 25.0K 2,924,467 I
2024-12-27 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 12.58 25.2K 2,926,467 I
2024-12-26 Ma Songjiang Director / Officer S-Sale D Common Stock 1,644 12.62 20.7K 2,928,823 I
2024-12-24 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 11.93 23.9K 2,930,467 I
2024-12-23 Ma Songjiang Director / Officer S-Sale D Common Stock 1,704 12.24 20.9K 2,932,763 I
2024-12-20 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.90 21.8K 2,934,467 I
2024-12-19 Ma Songjiang Director / Officer S-Sale D Common Stock 2,000 10.82 21.6K 2,936,467 I
2024-12-18 Ma Songjiang Director / Officer S-Sale D Common Stock 1,571 11.17 17.5K 2,938,896 I
2024-12-17 Ma Songjiang Director / Officer S-Sale D Common Stock 1,212 10.94 13.3K 2,941,255 I
2024-08-14 Ying Han Director / Officer A-Award A Stock Option (Right to Buy) 341,000 9.98 3.40M 341,000
2024-08-14 Parry Renate Director A-Award A Stock Option (Right to Buy) 52,000 9.98 519.0K 52,000
2024-08-14 Nussbaum Rodney L Director A-Award A Stock Option (Right to Buy) 52,000 9.98 519.0K 52,000
2024-08-14 Ma Songjiang Director / Officer A-Award A Stock Option (Right to Buy) 26,000 9.98 259.5K 26,000
2024-08-14 Luo Ying Director A-Award A Stock Option (Right to Buy) 26,000 9.98 259.5K 26,000
2024-08-14 Epstein David M. Director A-Award A Stock Option (Right to Buy) 52,000 9.98 519.0K 52,000
2024-08-14 Eastling Thomas Wilson Director A-Award A Stock Option (Right to Buy) 26,000 9.98 259.5K 26,000
2024-08-14 Chen Ruoyu Officer A-Award A Stock Option (Right to Buy) 50,000 9.98 499.0K 50,000
2024-08-14 Carmichael Gordon Director A-Award A Stock Option (Right to Buy) 52,000 9.98 519.0K 52,000
2024-08-06 Epstein David M. Director A-Award A Stock Option (Right to Buy) 1,866 10.79 20.1K 1,866
2024-06-28 USMAN NASSIM Director S-Sale D Common Stock 3,452 12.00 41.4K 1,636
2024-05-01 USMAN NASSIM Director M-Exempt D Stock Option (Right to Buy) 20,000 6.93 138.6K 281,652
2024-04-01 USMAN NASSIM Director M-Exempt A Common Stock 20,000 6.93 138.6K 21,636
2024-03-20 Nussbaum Rodney L 0 0.00 0
2024-03-15 USMAN NASSIM Director M-Exempt D Stock Option (Right to Buy) 20,000 6.93 138.6K 321,652
2024-01-03 Ma Songjiang Director / Officer S-Sale D Common Stock 833 11.85 9.9K 2,918,467 I

Executive team

Top executives
EBIT / Employee
19.8K
Shares Outstanding
96.99M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-05-04 DEFA14A
2026-04-27 DEFA14A
2026-04-27 DEF 14A
2026-04-16 PRE 14A
2025-04-21 DEFA14A
2025-04-21 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 SC 13D/A
2026-05-07 8-K
2026-05-07 3
2026-05-07 3
2026-05-07 3
2026-05-07 3
2026-05-06 SC 13D/A
2026-05-06 SC 13D/A
2026-05-06 4
2026-05-06 4

Executive team

NameTitleCompensationGender
Ping Zhang Interim Chief Executive Officer & Executive Chair 578.9K male
Weiguo Ye Chief Operating Officer 563.4K male
Han Ying Senior Vice President of Science 353.3K
Ruoyu Chen Chief Financial Officer 285.6K female
Songjiang Ma President & Director male
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
83.1 / 56.3
Company / Sector avg.
S (Social)
76.7 / 62.4
Company / Sector avg.
G (Governance)
76.7 / 60.9
Company / Sector avg.
ESG Total
78.9 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits