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Equillium, Inc. (EQ)

USD2.57 -0.19 (-6.82%)
US NASDAQ S&P 500 Healthcare Biotechnology
Address 2223 Avenida De La Playa 92037
La Jolla, CA, US
CEO Bruce D. Steel
IPO 2018-10-12
CIK 1746466 ISIN US29446K1060

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Description

Equillium, Inc. is a clinical-stage biopharmaceutical company focused on developing and bringing to market products designed to address severe autoimmune and inflammatory (immuno-inflammatory) disorders where current treatment options are insufficient. The company's primary drug candidate is itolizumab (EQ001), a monoclonal antibody in clinical development that targets the novel CD6 immune checkpoint receptor. Itolizumab is currently in Phase III trials for acute graft-versus-host disease, has completed Phase Ib studies for asthma, and is also undergoing Phase Ib trials for lupus nephritis. In addition to itolizumab, Equillium is advancing EQ101 for the treatment of cutaneous T cell lymphoma and alopecia areata, and EQ102, which targets various gastrointestinal conditions. Headquartered in La Jolla, California, the company was incorporated in 2017 and previously operated as Attenuate Biopharmaceuticals, Inc. before changing its name to Equillium, Inc. in May 2017.

Market Cap & Enterprise Value
Merger & Acquisition History
Target company Ticker Date Filing
Metacrine, Inc. MTCR 2022-10-26 View

Index membership

IndexAddedRemovedStatus
S&P 500 2006-05-17 Active
Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD2.57 -0.19 (-6.82%)
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Volume Profile
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Liquidity & share structure
Average Volume
731.1K
Beta
1.77
Float Shares
17.54M
Free Float %
49.4%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+1.76% +7.44% +35.88% +47.13% +175.00% +49.03% +504.55% +239.71% -56.00% -83.50% -83.50%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (12 ratings, all time) Buy
Price Targets & DCF
Current price
2.57
Low 6.00 +133.3%
Consensus 6.50 +152.7%
Median 6.50 +152.7%
High 7.00 +172.2%
DCF (Unlevered) 0.32 -87.7%
DCF (Levered) 0.32 -87.7%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 88% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 7 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
7.00
+172.2%
Last Quarter 2
6.50
+152.7%
Last Year 2
6.50
+152.7%
All Time 3
4.67
+81.6%
Quality scores
Altman Z-Score
8.85
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -99.7%
  • EPS growth Biotechnology: +29.7%
    -69.6% Q1'26: +75.0% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -19,910.0%
  • EBIT margin Biotechnology: +0.0%
    -18,180.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +159.9% Q1'26: +170.5% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.03× Q1'26: -0.03× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.67) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.32 Current price: 2.57
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
4 Rev. Ana.
6 EPS Ana.
Dec 2027
7 Rev. Ana.
6 EPS Ana.
Dec 2028
6 Rev. Ana.
7 EPS Ana.
Dec 2029
5 Rev. Ana.
2 EPS Ana.
Dec 2030
3 Rev. Ana.
5 EPS Ana.
Revenue
15.76M
est: 18.00M (-12.5%)
36.08M
est: 42.62M (-15.3%)
41.10M
est: 36.85M (+11.5%)
130.0K
est: 11.00M (-98.8%)
15.58M
15.58M – 15.58M
+41.6% YoY
16.52M
16.52M – 16.52M
+6.1% YoY
51.69M
51.69M – 51.69M
+212.8% YoY
89.24M
89.24M – 89.24M
+72.6% YoY
154.8K
154.8K – 154.8K
-99.8% YoY
EBITDA
-61.26M
est: 1.73M (-3,649.1%)
-12.14M
est: -12.96M (+6.4%)
-7.57M
est: -11.21M (+32.5%)
-23.52M
est: -3.35M (-603.0%)
-4.74M
-4.74M – -4.74M
-41.6% YoY
-5.03M
-5.03M – -5.03M
-6.1% YoY
-15.72M
-15.72M – -15.72M
-212.8% YoY
-27.14M
-27.14M – -27.14M
-72.6% YoY
-47.1K
-47.1K – -47.1K
+99.8% YoY
EBIT
-61.38M
est: 1.70M (-3,707.3%)
-12.26M
est: -13.02M (+5.8%)
-7.71M
est: -11.26M (+31.5%)
-23.63M
est: -3.36M (-603.3%)
-4.76M
-4.76M – -4.76M
-41.6% YoY
-5.05M
-5.05M – -5.05M
-6.1% YoY
-15.79M
-15.79M – -15.79M
-212.8% YoY
-27.26M
-27.26M – -27.26M
-72.6% YoY
-47.3K
-47.3K – -47.3K
+99.8% YoY
Net Income
-62.43M
est: -59.05M (-5.7%)
-13.34M
est: -21.74M (+38.7%)
-8.07M
est: -20.19M (+60.1%)
-22.40M
est: -37.90M (+40.9%)
-25.31M
-26.83M – -16.65M
+33.2% YoY
-22.82M
-29.41M – -16.23M
+9.8% YoY
-31.47M
-42.27M – -20.66M
-37.9% YoY
-31.06M
-31.06M – -31.06M
+1.3% YoY
-37.90M
-37.90M – -37.90M
-22.0% YoY
SGA
17.24M
est: 13.54M (+27.3%)
13.57M
est: 731.14M (-98.1%)
11.94M
est: 632.14M (-98.1%)
10.79M
est: 188.69M (-94.3%)
267.18M
267.18M – 267.18M
+41.6% YoY
283.45M
283.45M – 283.45M
+6.1% YoY
886.70M
886.70M – 886.70M
+212.8% YoY
1.53B
1.53B – 1.53B
+72.6% YoY
2.66M
2.66M – 2.66M
-99.8% YoY
EPS
-3.19
est: -1.67 (-91.0%)
-0.38
est: -0.24 (-60.6%)
-0.23
est: -0.38 (+38.7%)
-0.39
est: -0.41 (+5.5%)
-0.21
-0.29 – -0.18
+48.7% YoY
-0.24
-0.32 – -0.18
-14.9% YoY
-0.30
-0.46 – -0.22
-21.5% YoY
-0.34
-0.34 – -0.34
-14.6% YoY
-0.41
-0.41 – -0.41
-22.0% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-17 Roth Capital Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-13 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-12 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-11 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-08 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-20.94M
OE per share TTM
-0.45
Owner's Yield
-9.42%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
6.7%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
13
Total invested
11.42M
Insider transactions (90d)
0
Beneficial owners (>5%)
10
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Xiangmin Cui 5.73M 19.70% PN 2021-02-16
2 Decheng Capital Management III (Cayman), LLC 4.45M 15.13% 4.45M 4.45M 4.45M 4.45M IA OR PLACE OF ORGANIZATION 2022-02-14
3 IV, L.P. 4.27M 14.70% PN 2021-02-16
4 LLC 4.27M 14.70% OO 2021-02-16
5 Victory Capital Management Inc. 4.13M 14.04% 4.13M 4.13M IA New York 2022-02-01
6 Takeda Pharmaceutical Company Limited 1.84M 5.20% 1.84M CO 2024-01-19
7 Takeda Ventures, Inc. 1.84M 5.20% 1.84M CO 2024-01-19
8 (Master), LP 1.46M 5.00% PN 2021-02-16
9 Decheng Capital Global Healthcare GP, LLC 1.46M 5.00% OO 2021-02-16
10 Partner Fund Management, L.P. 6.00 7.20% 1.21M 1.21M IA, PN, IN Delaware 2018-10-22

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
13
-28 vs prev Q
New positions
6
Closed positions
30
Increased
10
Reduced
1
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 JANUS HENDERSON GROUP PLC 5.86M +5.9M (+100.0%) 9.06M +9.1M (+100.0%) 16.41% +16.412 pp 0.00% +0.004 pp USD1.55 +0.0% 1 qtrs NEW
2 ADAR1 CAPITAL MANAGEMENT, LLC 5.61M +48.1K (+0.9%) 8.69M +741.7K (+9.3%) 15.70% +0.135 pp 0.64% -0.108 pp USD1.43 +8.4% 2 qtrs
3 ADAGE CAPITAL PARTNERS GP, L.L.C. 5.33M +— (+0.0%) 8.26M +639.5K (+8.4%) 14.92% +0.000 pp 0.01% +0.000 pp USD1.43 +8.4% 2 qtrs
4 DECHENG CAPITAL LLC 4.45M +— (+0.0%) 6.89M +533.7K (+8.4%) 12.45% +0.000 pp 0.93% -0.182 pp USD0.72 +115.3% 9 qtrs
5 WOODLINE PARTNERS LP 3.50M -7.9K (-0.2%) 5.43M +408.9K (+8.1%) 9.80% -0.022 pp 0.02% -0.003 pp USD1.43 +8.4% 2 qtrs
6 ABRDN PLC 2.37M +2.0M (+523.6%) 3.67M +3.1M (+575.9%) 6.63% +5.563 pp 0.01% +0.005 pp USD1.53 +1.3% 2 qtrs
7 BALYASNY ASSET MANAGEMENT L.P. 2.08M +72.6K (+3.6%) 3.22M +353.0K (+12.3%) 5.81% +0.203 pp 0.00% +0.001 pp USD1.43 +8.4% 2 qtrs
8 VANGUARD GROUP INC 1.92M +606.5K (+46.2%) 2.98M +1.1M (+58.4%) 5.38% +1.698 pp 0.00% +0.000 pp USD3.54 -56.2% 29 qtrs
9 RENAISSANCE TECHNOLOGIES LLC 733.2K +118.3K (+19.2%) 1.14M +257.2K (+29.2%) 2.05% +0.331 pp 0.00% +0.001 pp USD1.19 +30.3% 15 qtrs
10 CANTOR FITZGERALD, L. P. 562.6K +137.6K (+32.4%) 872.1K +264.3K (+43.5%) 1.58% +0.385 pp 0.01% +0.007 pp USD1.46 +6.2% 2 qtrs
11 HUDSON BAY CAPITAL MANAGEMENT LP 428.5K +150.0K (+53.9%) 664.2K +265.9K (+66.8%) 1.20% +0.420 pp 0.00% +0.001 pp USD1.47 +5.4% 2 qtrs
12 DIADEMA PARTNERS LP 347.4K +47.4K (+15.8%) 538.5K +109.5K (+25.5%) 0.97% +0.133 pp 0.09% -0.017 pp USD1.45 +6.9% 2 qtrs
13 GEODE CAPITAL MANAGEMENT, LLC 345.3K +34.5K (+11.1%) 535.3K +90.8K (+20.4%) 0.97% +0.097 pp 0.00% +0.000 pp USD3.42 -54.7% 22 qtrs
14 TWO SIGMA INVESTMENTS, LP 324.6K +191.6K (+144.1%) 503.1K +313.0K (+164.5%) 0.91% +0.536 pp 0.00% +0.000 pp USD1.50 +3.3% 2 qtrs
15 IKARIAN CAPITAL, LLC 303.6K -28.7K (-8.6%) 470.5K -4.7K (-1.0%) 0.85% -0.081 pp 0.04% -0.011 pp USD1.43 +8.4% 2 qtrs
16 TUDOR INVESTMENT CORP ET AL 258.8K +258.8K (+100.0%) 401.1K +401.1K (+100.0%) 0.72% +0.725 pp 0.00% +0.001 pp USD1.55 +0.0% 1 qtrs NEW
17 SUSQUEHANNA INTERNATIONAL GROUP, LLP 185.7K +185.7K (+100.0%) 287.8K +287.8K (+100.0%) 0.52% +0.520 pp 0.00% +0.000 pp USD1.55 +0.0% 8 qtrs
18 STATE STREET CORP 155.4K +17.9K (+13.0%) 240.9K +44.2K (+22.5%) 0.44% +0.050 pp 0.00% +0.000 pp USD2.92 -46.9% 19 qtrs
19 BLACKROCK, INC. 126.1K +— (+0.0%) 195.4K +15.1K (+8.4%) 0.35% +0.000 pp 0.00% +0.000 pp USD1.43 +8.4% 6 qtrs
20 JANE STREET GROUP, LLC 100.9K +100.9K (+100.0%) 156.3K +156.3K (+100.0%) 0.28% +0.282 pp 0.00% +0.000 pp USD1.55 +0.0% 1 qtrs NEW
21 BOOTHBAY FUND MANAGEMENT, LLC 93.2K -28.7K (-23.6%) 144.5K -29.9K (-17.2%) 0.26% -0.081 pp 0.00% 0.000 pp USD1.43 +8.4% 2 qtrs
22 PERSISTENT ASSET PARTNERS LTD 93.1K +24.1K (+35.0%) 144.3K +45.7K (+46.3%) 0.26% +0.068 pp 0.06% -0.003 pp USD1.46 +6.2% 2 qtrs
23 NORTHERN TRUST CORP 88.5K +53.5K (+152.8%) 137.2K +87.1K (+174.0%) 0.25% +0.150 pp 0.00% +0.000 pp USD3.21 -51.7% 22 qtrs
24 ROYAL BANK OF CANADA 79.7K +79.7K (+100.0%) 124.0K +124.0K (+100.0%) 0.22% +0.223 pp 0.00% +0.000 pp USD1.55 +0.0% 1 qtrs NEW
25 CITADEL ADVISORS LLC 79.6K +79.6K (+100.0%) 123.4K +123.4K (+100.0%) 0.22% +0.223 pp 0.00% +0.000 pp USD1.55 +0.0% 1 qtrs NEW
26 ALPHACORE CAPITAL LLC 52.3K +— (+0.0%) 81.1K +6.3K (+8.4%) 0.15% +0.000 pp 0.00% -0.001 pp USD0.32 +384.4% 3 qtrs
27 TWO SIGMA ADVISERS, LP 44.1K +44.1K (+100.0%) 68.4K +68.4K (+100.0%) 0.12% +0.124 pp 0.00% +0.000 pp USD1.55 +0.0% 1 qtrs NEW
28 MORGAN STANLEY 35.7K +25.6K (+254.3%) 55.4K +41.0K (+284.1%) 0.10% +0.072 pp 0.00% +0.000 pp USD1.35 +14.8% 5 qtrs
29 SCHONFELD STRATEGIC ADVISORS LLC 25.4K -99.4K (-79.7%) 39.3K -139.2K (-78.0%) 0.07% -0.278 pp 0.00% -0.001 pp USD1.43 +8.4% 2 qtrs
30 APOLLON WEALTH MANAGEMENT, LLC 13.9K +— (+0.0%) 21.5K +1.7K (+8.4%) 0.04% +0.000 pp 0.00% +0.000 pp USD0.32 +384.4% 3 qtrs
31 COASTAL BRIDGE ADVISORS, LLC 10.5K +10.5K (+100.0%) 16.3K +16.3K (+100.0%) 0.03% +0.029 pp 0.00% +0.001 pp USD1.55 +0.0% 1 qtrs NEW
32 TOWER RESEARCH CAPITAL LLC (TRC) 4.1K -2.3K (-36.5%) 6.3K -2.9K (-31.1%) 0.01% -0.007 pp 0.00% 0.000 pp USD0.70 +121.4% 5 qtrs
33 WELLS FARGO & COMPANY/MN 1.0K +— (+0.0%) 1.6K +120.0 (+8.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD6.82 -77.3% 20 qtrs
34 UBS GROUP AG 920.00 -27.1K (-96.7%) 1.4K -38.7K (-96.4%) 0.00% -0.076 pp 0.00% +0.000 pp USD0.32 +384.4% 7 qtrs
35 BANK OF AMERICA CORP /DE/ 295.00 +21.0 (+7.7%) 457.00 +65.0 (+16.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD0.98 +58.2% 9 qtrs
36 SBI SECURITIES CO., LTD. 283.00 -162.0 (-36.4%) 439.00 -197.0 (-31.0%) 0.00% -0.001 pp 0.00% +0.000 pp USD0.70 +121.4% 5 qtrs
37 JONES FINANCIAL COMPANIES LLLP 250.00 +250.0 (+100.0%) 388.00 +388.0 (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD1.55 +0.0% 1 qtrs NEW
38 MARSHALL WACE, LLP -41.2K (-100.0%) -58.9K (-100.0%) 0.00% -0.115 pp 0.00% 0.000 pp USD 2 qtrs SOLD
39 STEMPOINT CAPITAL LP -1.9M (-100.0%) -2.7M (-100.0%) 0.00% -5.344 pp 0.00% -0.547 pp USD 2 qtrs SOLD
40 RISE ADVISORS, LLC -263.0 (-100.0%) -376.0 (-100.0%) 0.00% -0.001 pp 0.00% 0.000 pp USD 2 qtrs SOLD
41 FMR LLC -200.0 (-100.0%) -286.0 (-100.0%) 0.00% -0.001 pp 0.00% +0.000 pp USD 2 qtrs SOLD
42 ENGINEERS GATE MANAGER LP -39.7K (-100.0%) -56.8K (-100.0%) 0.00% -0.111 pp 0.00% -0.001 pp USD 2 qtrs SOLD
43 TWO SIGMA SECURITIES, LLC -10.5K (-100.0%) -15.1K (-100.0%) 0.00% -0.030 pp 0.00% -0.002 pp USD 2 qtrs SOLD
44 MILLENNIUM MANAGEMENT LLC -24.4K (-100.0%) -34.8K (-100.0%) 0.00% -0.068 pp 0.00% +0.000 pp USD 2 qtrs SOLD
45 BARCLAYS PLC -104.0 (-100.0%) -87.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 2 qtrs SOLD
46 VIRTU FINANCIAL LLC -23.8K (-100.0%) -34.0K (-100.0%) 0.00% -0.067 pp 0.00% -0.002 pp USD 6 qtrs SOLD
47 SIMPLEX TRADING, LLC -1.9K (-100.0%) -2.0K (-100.0%) 0.00% -0.005 pp 0.00% +0.000 pp USD 11 qtrs SOLD
48 PRUDENTIAL FINANCIAL INC -28.3K (-100.0%) -40.5K (-100.0%) 0.00% -0.079 pp 0.00% +0.000 pp USD 3 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 16 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Invesco NASDAQ Future Gen 200 ETF QQQS 0.50% 110.1K 0.20%
2 iShares Micro-Cap ETF IWC 0.03% 429.8K 0.60%
3 Avantis U.S. Small Cap Equity ETF AVSC 0.00% 77.6K 0.25%
4 Vanguard Extended Market ETF VXF 0.00% 976.5K 0.05%
5 U.S. Micro Cap Portfolio ETF DFMC 0.00% 23.2K 0.43%
6 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 1.7K 0.17%
7 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 8.6K 0.03%
8 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 23.7K 0.17%
9 Vanguard Total Stock Market ETF VTI 0.00% 4.04M 0.03%
10 Dimensional - US Small Cap ETF DFAS 0.00% 22.7K 0.26%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.22
Neutral
Ratio by volume
3.00
Bullish
Buys
11
Sells
9
Shares acquired
4.37M
Shares disposed
820.6K
Cash buys
Cash sales
6.00
Net activity
+3,553,672
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-13 Zedelmayer Christine Officer M-Exempt A Common Stock 120,312 0.79 94.4K 182,898 D
2026-03-09 Zedelmayer Christine Officer M-Exempt A Common Stock 75,000 0.79 58.9K 243,805 D
2026-02-19 Zedelmayer Christine Officer M-Exempt A Common Stock 109,375 0.79 85.9K 300,819 D
2026-01-08 Tom Penny Officer S-Sale D Common Stock 6,533 1.29 8.4K 0 D
2026-01-07 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 500,000 1.31 655.0K 500,000 D
2026-01-07 Tom Penny Officer A-Award A Employee Stock Option (right to buy) 450,000 1.31 589.5K 450,000 D
2026-01-07 Steel Bruce D. Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 1,750,000 1.31 2.29M 1,750,000 D
2026-01-07 Connelly Stephen Director / Officer A-Award A Employee Stock Option (right to buy) 1,150,000 1.31 1.51M 1,150,000 D
2025-12-23 Zedelmayer Christine Officer M-Exempt A Common Stock 100,000 0.79 78.5K 191,444 D
2025-12-15 Zedelmayer Christine Officer S-Sale D Common Stock 11,900 1.31 15.6K 91,444 D
2025-12-12 Zedelmayer Christine Officer S-Sale D Common Stock 23,804 1.34 31.9K 103,344 D
2025-11-25 Zedelmayer Christine Officer S-Sale D Common Stock 100 0.98 98.00 135,146 D
2025-08-29 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 725,000 1.74 1.26M 725,000 D
2025-08-29 Tom Penny Officer A-Award A Employee Stock Option (right to buy) 525,000 1.74 913.5K 525,000 D
2025-08-29 Steel Bruce D. Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 1,695,000 1.74 2.95M 1,695,000 D
2025-08-29 Connelly Stephen Director / Officer A-Award A Employee Stock Option (right to buy) 1,025,000 1.74 1.78M 1,025,000 D
2025-05-21 Troupin Barbara Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-05-21 Pruzanski Mark Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-05-21 McDermott Charles Douglas Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-05-21 MANIAN BALA S Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-05-21 DEMSKI MARTHA J Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-05-21 Colabuono Peter Director A-Award A Director Stock Option (right to buy) 20,000 0.39 7.8K 20,000 D
2025-02-14 Zedelmayer Christine Officer D-Return D Employee Stock Option (right to buy) 125,000 3.86 482.5K 0 D
2025-02-14 Troupin Barbara Director D-Return D Director Stock Option (right to buy) 40,000 3.59 143.6K 0 D
2025-02-14 Tom Penny Officer D-Return D Employee Stock Option (right to buy) 60,000 3.86 231.6K 0 D
2025-02-14 Steel Bruce D. Director / Officer / 10% Owner D-Return D Employee Stock Option (right to buy) 100,000 4.75 475.0K 0 D
2025-02-14 Pruzanski Mark Director D-Return D Director Stock Option (right to buy) 12,000 6.01 72.1K 0 D
2025-02-14 MANIAN BALA S Director A-Award A Director Stock Option (right to buy) 20,634 0.79 16.2K 20,634 D
2025-02-14 Keyes Jason A Officer A-Award A Employee Stock Option (right to buy) 175,000 0.79 137.4K 175,000 D
2025-02-14 DEMSKI MARTHA J Director D-Return D Director Stock Option (right to buy) 12,000 6.01 72.1K 0 D
2025-02-14 Connelly Stephen Director / Officer D-Return D Employee Stock Option (right to buy) 175,000 1.06 185.5K 0 D
2025-02-14 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 90,000 0.79 70.7K 90,000 D
2025-01-23 Keyes Jason A Officer S-Sale D Common Stock 10,000 0.65 6.5K 37,720 I
2025-01-02 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 175,000 0.77 134.8K 175,000 D
2025-01-02 Tom Penny Officer A-Award A Employee Stock Option (right to buy) 125,000 0.77 96.3K 125,000 D
2025-01-02 Steel Bruce D. Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 410,000 0.77 315.7K 410,000 D
2025-01-02 Keyes Jason A Officer A-Award A Employee Stock Option (right to buy) 175,000 0.77 134.8K 175,000 D
2025-01-02 Connelly Stephen Director / Officer A-Award A Employee Stock Option (right to buy) 175,000 0.77 134.8K 175,000 D
2025-01-02 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 50,000 0.77 38.5K 50,000 D
2024-12-11 Colabuono Peter Director A-Award A Director Stock Option (right to buy) 40,000 0.70 28.0K 40,000 D
2024-12-10 Keyes Jason A Officer A-Award A Common Stock 15,000 0.54 8.1K 88,913 D
2024-11-14 Keyes Jason A Officer S-Sale D Common Stock 10,000 0.70 7.0K 47,720 I
2024-10-28 Zedelmayer Christine Officer S-Sale D Common Stock 15,000 1.25 18.8K 135,246 D
2024-10-28 Tom Penny Officer S-Sale D Common Stock 2,835 1.25 3.5K 6,533 D
2024-10-25 Tom Penny Officer S-Sale D Common Stock 683 1.25 853.75 9,368 D
2024-09-26 Keyes Jason A Officer S-Sale D Common Stock 10,000 0.81 8.1K 57,720 I
2024-09-16 Tom Penny Officer S-Sale D Common Stock 38,806 0.85 33.0K 10,051
2024-07-16 Keyes Jason A Officer S-Sale D Common Stock 10,000 0.87 8.7K 67,720
2024-05-22 Xu Yu (Katherine) Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-05-22 Troupin Barbara Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-05-22 Pruzanski Mark Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-05-22 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-05-22 MANIAN BALA S Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-05-22 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 20,000 1.43 28.6K 20,000
2024-03-06 Tom Penny Officer D Employee Stock Option (right to buy) 40,000 5.03 201.2K 0
2024-01-02 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 175,000 0.73 127.8K 175,000
2024-01-02 Steel Bruce D. Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 410,000 0.73 299.3K 410,000
2024-01-02 Rothman Joel Officer A-Award A Employee Stock Option (right to buy) 175,000 0.73 127.8K 175,000
2024-01-02 Keyes Jason A Officer A-Award A Employee Stock Option (right to buy) 175,000 0.73 127.8K 175,000
2024-01-02 Connelly Stephen Director / Officer A-Award A Employee Stock Option (right to buy) 175,000 0.73 127.8K 175,000
2024-01-02 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 50,000 0.73 36.5K 50,000
2023-12-08 Zedelmayer Christine Officer A-Award A Common Stock 8,804 0.58 5.1K 135,246
2023-12-08 Rothman Joel Officer A-Award A Common Stock 8,804 0.58 5.1K 58,150
2023-12-08 Keyes Jason A Officer A-Award A Common Stock 8,805 0.58 5.1K 58,913
2023-06-09 Zedelmayer Christine Officer A-Award A Common Stock 15,000 0.56 8.4K 126,442
2023-06-09 Rothman Joel Officer A-Award A Common Stock 15,000 0.56 8.4K 49,346
2023-06-09 Keyes Jason A Officer A-Award A Common Stock 15,000 0.56 8.4K 50,108
2023-05-22 Xu Yu (Katherine) Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-05-22 Troupin Barbara Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-05-22 Pruzanski Mark Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-05-22 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-05-22 MANIAN BALA S Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-05-22 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 20,000 0.65 13.0K 20,000
2023-01-03 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 175,000 0.00 175,000
2023-01-03 Steel Bruce D. Officer A-Award A Employee Stock Option (right to buy) 410,000 0.00 410,000
2023-01-03 Rothman Joel Officer A-Award A Employee Stock Option (right to buy) 175,000 0.00 175,000
2023-01-03 Keyes Jason A Officer A-Award A Employee Stock Option (right to buy) 175,000 0.00 175,000
2023-01-03 Connelly Stephen Officer A-Award A Employee Stock Option (right to buy) 175,000 0.00 175,000
2023-01-03 BRADBURY DANIEL Officer A-Award A Employee Stock Option (right to buy) 50,000 0.00 50,000
2022-12-09 Rothman Joel Officer A-Award A Common Stock 3,821 1.19 4.5K 34,346
2022-12-09 Keyes Jason A Officer A-Award A Common Stock 4,444 1.19 5.3K 35,108
2022-08-29 Keyes Jason A Officer S-Sale D Common Stock 7,000 2.83 19.8K 77,720
2022-06-10 Zedelmayer Christine Officer A-Award A Common Stock 9,033 1.85 16.7K 111,442
2022-06-10 Rothman Joel Officer A-Award A Common Stock 6,244 1.85 11.6K 30,525
2022-06-06 Keyes Jason A Officer S-Sale D Common Stock 5,000 2.52 12.6K 84,720
2022-05-24 Xu Yu (Katherine) Director A-Award A Stock Option (right to buy) 20,000 0.00 20,000
2022-05-24 Pruzanski Mark Director A-Award A Stock Option (right to buy) 20,000 0.00 20,000
2022-05-24 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 20,000 0.00 20,000
2022-05-24 MANIAN BALA S Director A-Award A Stock Option (right to buy) 20,000 0.00 20,000
2022-05-24 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 20,000 0.00 20,000
2022-04-04 Keyes Jason A Officer S-Sale D Common Stock 8,000 3.18 25.4K 89,720
2022-03-01 Troupin Barbara Director A-Award A Stock Option (right to buy) 40,000 0.00 40,000
2022-03-01 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 38,000 3.59 136.4K 38,000
2022-02-24 Troupin Barbara Director 0 0.00 0
2022-01-19 Zedelmayer Christine Officer A-Award A Employee Stock Option (right to buy) 125,000 3.86 482.5K 125,000
2022-01-19 Steel Bruce D. Director / Officer / 10% Owner A-Award A Employee Stock Option (right to buy) 325,000 3.86 1.25M 325,000
2022-01-19 Rothman Joel Officer A-Award A Employee Stock Option (right to buy) 125,000 3.86 482.5K 125,000
2022-01-19 Keyes Jason A Officer A-Award A Employee Stock Option (right to buy) 125,000 3.86 482.5K 125,000
2022-01-19 Connelly Stephen Director / Officer A-Award A Employee Stock Option (right to buy) 125,000 3.86 482.5K 125,000
2021-12-10 Rothman Joel Officer A-Award A Common Stock 1,290 2.35 3.0K 24,281
2021-12-10 Keyes Jason A Officer A-Award A Common Stock 5,585 2.35 13.1K 23,296
2021-12-01 Keyes Jason A Officer S-Sale D Common Stock 5,000 5.08 25.4K 97,720
2021-11-16 Zedelmayer Christine Officer M-Exempt A Common Stock 15,000 2.45 36.8K 109,759
2021-10-06 Connelly Stephen Director / Officer M-Exempt D Employee Stock Option (right to buy) 2,467 2.80 6.9K 0
2021-09-27 Keyes Jason A Officer S-Sale D Common Stock 8,000 6.74 53.9K 102,720
2021-07-27 Keyes Jason A Officer S-Sale D Common Stock 5,000 5.72 28.6K 110,720
2021-06-10 Zedelmayer Christine Officer A-Award A Common stock, par value $0.0001 per share 9,032 2.35 21.2K 90,509
2021-06-10 Rothman Joel Officer A-Award A Common stock, par value $0.0001 per share 7,742 2.35 18.2K 22,991
2021-06-10 Keyes Jason A Officer A-Award A Common stock, par value $0.0001 per share 5,535 2.35 13.0K 17,711
2021-06-08 Connelly Stephen Director / Officer M-Exempt A Common Stock 10,495 4.75 49.9K 1,003,495
2021-06-07 Connelly Stephen Director / Officer M-Exempt D Employee Stock Option (right to buy) 8,490 2.80 23.8K 0
2021-06-04 Connelly Stephen Director / Officer S-Sale D Common Stock 6,509 7.01 45.6K 993,000
2021-05-26 Pruzanski Mark Director A-Award A Stock Option (right to buy) 20,770 6.55 136.0K 20,770
2021-05-26 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 20,770 6.55 136.0K 20,770
2021-05-26 MANIAN BALA S Director A-Award A Stock Option (right to buy) 20,770 6.55 136.0K 20,770
2021-05-26 Keyes Jason A Officer S-Sale D Common Stock 5,000 6.50 32.5K 115,720
2021-05-26 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 20,770 6.55 136.0K 20,770
2021-03-04 Xu Yu (Katherine) Director A-Award A Stock Option (right to buy) 30,000 6.69 200.7K 30,000
2021-02-05 Decheng Capital Global Life Sciences Fund IV, L.P. 10% Owner I Warrant (right to buy) 985,713 14.00 13.80M 0
2021-02-04 Xu Yu (Katherine) Director D No securities are beneficially owned 0 0.00 0
2021-01-26 Rothman Joel Officer D Common Stock 0 0.00 15,249
2021-01-11 Thomas Dolca Officer A-Award A Stock Option (right to buy) 450,000 5.20 2.34M 450,000
2021-01-04 Zedelmayer Christine Officer A-Award A Stock Option (right to buy) 100,000 5.03 503.0K 100,000
2021-01-04 Steel Bruce D. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 245,000 5.03 1.23M 245,000
2021-01-04 Keyes Jason A Officer A-Award A Stock Option (right to buy) 100,000 5.03 503.0K 100,000
2021-01-04 Connelly Stephen Director / Officer A-Award A Stock Option (right to buy) 100,000 5.03 503.0K 100,000
2021-01-04 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 36,000 5.03 181.1K 36,000
2020-12-28 Connelly Stephen Director / Officer S-Sale D Common Stock 25,000 4.52 113.0K 993,000
2020-12-23 Keyes Jason A Officer S-Sale D Common Stock 8,000 4.74 37.9K 120,720
2020-12-10 Zedelmayer Christine Officer J-Other A Common Stock 1,097 2.35 2.6K 81,477
2020-12-10 Keyes Jason A Officer J-Other A Common Stock 5,362 2.35 12.6K 12,176
2020-09-28 Connelly Stephen Director / Officer S-Sale D Common Stock 25,000 5.62 140.4K 1,018,000
2020-07-13 Connelly Stephen Director / Officer S-Sale D Common Stock 250,000 8.13 2.03M 1,043,000
2020-06-10 Zedelmayer Christine Officer J-Other A Common Stock 9,570 2.41 23.1K 80,380
2020-06-10 Keyes Jason A Officer J-Other A Common Stock 5,014 2.41 12.1K 6,814
2020-05-28 Steel Bruce D. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 100,110 3.53 353.4K 100,110
2020-05-28 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 19,916 3.53 70.3K 19,916
2020-05-28 MANIAN BALA S Director A-Award A Stock Option (right to buy) 20,634 3.53 72.8K 20,634
2020-05-28 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 28,708 3.53 101.3K 28,708
2020-05-19 Steel Bruce D. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 60,000 2.80 168.0K 60,000
2020-05-19 Pruzanski Mark Director A-Award A Stock Option (right to buy) 24,000 2.80 67.2K 24,000
2020-05-19 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 24,000 2.80 67.2K 24,000
2020-05-19 MANIAN BALA S Director A-Award A Stock Option (right to buy) 24,000 2.80 67.2K 24,000
2020-05-19 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 24,000 2.80 67.2K 24,000
2020-05-19 Connelly Stephen Director / Officer A-Award A Stock Option (right to buy) 60,000 2.80 168.0K 60,000
2020-04-22 Zedelmayer Christine Officer D-Return D Stock Option (right to buy) 90,000 4.75 427.5K 0
2020-04-22 Polu Krishna R Officer D-Return D Stock Option (right to buy) 90,000 7.16 644.4K 0
2020-04-22 Keyes Jason A Officer D-Return D Stock Option (right to buy) 70,000 7.16 501.2K 0
2020-02-18 Keyes Jason A Officer S-Sale D Common Stock 5,000 5.03 25.1K 130,520
2020-01-21 Keyes Jason A Officer S-Sale D Common Stock 5,000 4.41 22.0K 135,520
2020-01-01 Zedelmayer Christine Officer D Common Stock 0 0.00 70,810
2019-12-10 Steel Bruce D. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 100,000 4.75 475.0K 100,000
2019-12-10 Polu Krishna R Officer A-Award A Stock Option (right to buy) 125,000 4.75 593.8K 125,000
2019-12-10 Keyes Jason A Officer A-Award A Stock Option (right to buy) 90,000 4.75 427.5K 90,000
2019-12-10 Connelly Stephen Director / Officer A-Award A Stock Option (right to buy) 90,000 4.75 427.5K 90,000
2019-12-10 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 36,000 4.75 171.0K 36,000
2019-09-03 Keyes Jason A Officer S-Sale D Common Stock 5,000 3.60 18.0K 138,720
2019-08-01 Keyes Jason A Officer S-Sale D Common Stock 5,000 3.99 19.9K 143,720
2019-06-11 Pruzanski Mark Director A-Award A Stock Option (right to buy) 12,000 6.01 72.1K 12,000
2019-06-11 McDermott Charles Douglas Director A-Award A Stock Option (right to buy) 12,000 6.01 72.1K 12,000
2019-06-11 MANIAN BALA S Director A-Award A Stock Option (right to buy) 12,000 6.01 72.1K 12,000
2019-06-11 DEMSKI MARTHA J Director A-Award A Stock Option (right to buy) 12,000 6.01 72.1K 12,000
2019-02-13 Steel Bruce D. Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 45,648 7.88 359.7K 45,648
2019-02-13 Polu Krishna R Officer A-Award A Stock Option (right to buy) 90,000 7.16 644.4K 90,000
2019-02-13 Keyes Jason A Officer A-Award A Stock Option (right to buy) 70,000 7.16 501.2K 70,000
2019-02-13 Connelly Stephen Director / Officer A-Award A Stock Option (right to buy) 90,000 7.16 644.4K 90,000
2019-02-13 BRADBURY DANIEL Director / Officer / 10% Owner A-Award A Stock Option (right to buy) 90,000 7.16 644.4K 90,000
2018-10-16 Steel Bruce D. Director / Officer J-Other A Common Stock 48,495 11.20 543.1K 48,495
2018-10-16 Biocon SA 10% Owner A-Award A Common Stock 228,060 0.00 2,316,134
2018-10-16 BRADBURY DANIEL Director / Officer J-Other A Common Stock 38,796 11.20 434.5K 2,969,596
2018-10-11 Steel Bruce D. Director / Officer I Common Stock 0 0.00 431,000
2018-10-11 Pruzanski Mark Director D Common Stock 0 0.00 23,799
2018-10-11 Polu Krishna R Officer D Stock Option (right to buy) 208,216 3.30 687.1K 0
2018-10-11 McDermott Charles Douglas Director I Common Stock 0 0.00 23,799
2018-10-11 MANIAN BALA S Director D Common Stock 0 0.00 23,799
2018-10-11 Keyes Jason A Officer I Common Stock 0 0.00 148,720
2018-10-11 DEMSKI MARTHA J Director I Common Stock 0 0.00 23,799
2018-10-11 Connelly Stephen Director / Officer D Common Stock 0 0.00 1,293,000
2018-10-11 Biocon SA 10% Owner D Common Stock 0 0.00 2,088,074
2018-10-11 BRADBURY DANIEL Director / Officer I Common Stock 0 0.00 2,930,800
2009-07-01 Toussaint Claudia S Officer D-Return D NQ Stock Option 3,886 45.19 175.6K 0
2009-07-01 SHERN STEPHANIE M Director D-Return D Common Stock 7,842 0.00 0
2009-07-01 Paliwal Dinesh C Director D-Return D Common Stock 6,981 0.00 0
2009-07-01 OWENS WILLIAM ARTHUR Director D-Return D Common Stock 11,993 0.00 0
2009-07-01 Huber Dennis G Officer D-Return D NQ Stock Option 23,728 41.94 995.2K 0
2009-07-01 GERKE THOMAS A Director / Officer D-Return D NQ Stock Option 9,495 48.10 456.7K 0
2009-07-01 GEPHARDT Richard A Director D-Return D Common Stock 1,879 0.00 0
2009-07-01 Davis Steven A Director D-Return D Common Stock 6,981 0.00 0
2009-07-01 BETTS GENE M Officer D-Return D NQ Stock Option 6,385 43.06 274.9K 0
2009-05-21 Toussaint Claudia S Officer M-Exempt A Common Stock 1,316 0.00 13,384
2009-05-21 Huber Dennis G Officer F-InKind D Common Stock 1,269 40.24 51.1K 23,999
2009-05-21 GERKE THOMAS A Officer F-InKind D Common Stock 4,556 40.24 183.3K 64,039
2009-05-21 BETTS GENE M Officer F-InKind D Common Stock 3,040 40.24 122.3K 37,920
2009-05-01 SHERN STEPHANIE M Director M-Exempt A Common Stock 1,879 0.00 7,842
2009-05-01 Paliwal Dinesh C Director M-Exempt D Restricted Stock Units 1,879 0.00 0
2009-05-01 OWENS WILLIAM ARTHUR Director M-Exempt D Restricted Stock Units 1,879 0.00 5,012
2009-05-01 GEPHARDT Richard A Director M-Exempt A Common Stock 1,879 0.00 1,879
2009-05-01 Davis Steven A Director M-Exempt D Restricted Stock Units 1,879 0.00 0
2009-04-30 SHERN STEPHANIE M Director M-Exempt D Restricted Stock Units 3,720 0.00 1,879
2009-04-30 Paliwal Dinesh C Director M-Exempt D Restricted Stock Units 3,720 0.00 1,879

Executive team

Top executives
EBIT / Employee
-16.9K
Shares Outstanding
35.52M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Bruce D. Steel Chief Executive Officer 519.2K 353.5K 3.02M 361.8K 4.26M 70.99%
2 2025 Stephen Connelly, Ph.D. President and Chief Scientific Officer 455.2K 271.4K 1.78M 200.0K 2.70M 65.71%
3 2025 Christine Zedelmayer Chief Operating Officer 441.3K 175.0K 1.29M 194.0K 2.10M 61.45%
4 2024 Bruce D. Steel Chief Executive Officer 471.3K 213.1K 684.4K 31.13%
5 2024 Bruce D. Steel President and Chief Executive Officer 471.3K 213.1K 648.4K 32.86%
6 2024 Stephen Connelly, Ph.D. Chief Scientific Officer 428.5K 90.9K 519.4K 17.51%
7 2024 Stephen Connelly, Ph.D. President and Chief Scientific Officer 428.5K 90.9K 519.4K 17.51%
8 2024 Christine Zedelmayer Chief Operating Officer 415.3K 90.9K 506.2K 17.96%
9 2023 Bruce D. Steel President and Chief Executive Officer 455.4K 568.3K 324.5K 1.35M 42.16%
10 2023 Stephen Connelly, Ph.D. Chief Scientific Officer 414.0K 255.9K 157.3K 827.3K 30.94%
11 2023 Christine Zedelmayer Senior Vice President, Chief Operating Officer 401.3K 231.8K 152.5K 785.5K 29.51%
12 2023 Christine Zedelmayer Chief Operating Officer 401.3K 231.8K 152.5K 785.5K 29.51%
13 2022 Bruce D. Steel President and Chief Executive Officer 455.4K 881.9K 341.6K 1.68M 52.53%
14 2022 Stephen Connelly, Ph.D. Chief Scientific Officer 414.0K 339.2K 165.6K 918.8K 36.92%
15 2022 Christine Zedelmayer Senior Vice President, Chief Operating Officer 401.3K 339.2K 160.5K 900.9K 37.65%
16 2021 Dolca Thomas, M.D. Former Executive Vice President, Research and Development and Chief Medical Officer 470.4K 1.72M 146.3K 2.34M 73.61%
17 2021 Bruce D. Steel President and Chief Executive Officer 440.0K 903.7K 208.6K 1.55M 58.22%
18 2021 Stephen Connelly, Ph.D. Chief Scientific Officer 400.0K 368.8K 126.4K 895.2K 41.20%
19 2020 Bruce D. Steel President and Chief Executive Officer 198.4K 367.9K 216.0K 782.3K 47.03%
20 2020 Stephen Connelly, Ph.D. Chief Scientific Officer 386.3K 123.2K 130.4K 639.8K 19.26%
21 2020 Krishna R. Polu, M.D. Former Executive Vice President, Research and Development and Chief Medical Officer 450.0K 162.0K 612.0K 0.00%
22 2019 Krishna R. Polu, M.D. Executive Vice President, Research and Development and Chief Medical Officer 409.4K 951.4K 147.4K 1.51M 63.08%
23 2019 Krishna R. Polu, M.D. Former Executive Vice President, Research and Development and Chief Medical Officer 409.4K 951.4K 147.4K 1.51M 63.08%
24 2019 Bruce D. Steel President and Chief Executive Officer; former Chief Business Offer 395.8K 820.5K 142.5K 1.36M 60.38%
25 2019 Bruce D. Steel President and Chief Executive Officer 395.8K 820.5K 142.5K 1.36M 60.38%
26 2019 Daniel M. Bradbury Executive Chairman of the Board of Directors; former Chief Executive Officer 425.0K 625.4K 153.0K 1.20M 51.97%
27 2019 Stephen Connelly, Ph.D. Chief Scientific Officer 362.5K 122.3K 484.8K 0.00%
28 2018 Krishna R. Polu, M.D. Chief Medical Officer 143.8K 2.15M 43.1K 2.34M 92.00%
29 2018 Krishna R. Polu, M.D. Executive Vice President, Research and Development and Chief Medical Officer 143.8K 2.15M 43.1K 2.34M 92.00%
30 2018 Stephen Connelly, Ph.D. Chief Scientific Officer 268.8K 105.0K 373.8K 0.00%
31 2018 Daniel M. Bradbury Executive Chairman of the Board of Directors; former Chief Executive Officer 233.3K 81.7K 315.0K 0.00%
32 2018 Daniel M. Bradbury Chief Executive Officer 233.3K 81.7K 315.0K 0.00%
33 2018 Bruce D. Steel President and Chief Executive Officer; former Chief Business Offer 218.8K 76.6K 295.3K 0.00%
34 2017 Stephen Connelly, Ph.D. Chief Scientific Officer 30.0K 30.0K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-15 DEFA14A
2026-04-15 DEF 14A
2026-03-30 PRE 14A
2025-04-10 DEFA14A
2025-04-10 DEF 14A
2025-03-28 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-13 8-K
2026-05-13 10-Q
2026-05-07 SC 13G
2026-04-16 EFFECT
2026-04-15 DEFA14A
2026-04-15 DEF 14A
2026-04-15 ARS
2026-04-07 S-3
2026-03-30 PRE 14A
2026-03-25 S-8

Executive team

NameTitleCompensationGender
Bruce D. Steel Co-Founder, Chief Executive Officer & Director 1M male
Stephen Connelly Chief Scientific Officer & President 926.6K
Christine Zedelmayer Senior Vice President & Chief Operating Officer 810.3K female
Lisette Acevedo Vice President of Clinical Development
Michael Moore Vice President of Investor Relations & Corporate Communications male
Penny Tom Senior Vice President of Finance & Principal Accounting Officer female
ESG Rating
B
BIOTECHNOLOGY
Rank: 314 out of 662
2026
E (Environmental)
54.4 / 56.3
Company / Sector avg.
S (Social)
62.9 / 62.4
Company / Sector avg.
G (Governance)
57.6 / 60.9
Company / Sector avg.
ESG Total
58.3 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits