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Design Therapeutics, Inc. (DSGN)

USD13.37 -0.30 (-2.18%)
US NASDAQ Healthcare Biotechnology
Address 6005 Hidden Valley Road 92011
Carlsbad, CA, US
CEO Pratik Shah
IPO 2021-03-29
CIK 1807120 ISIN US25056L1035

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Description

Design Therapeutics, Inc. is a biopharmaceutical company in the preclinical phase that focuses on creating treatments for genetic conditions stemming from nucleotide repeat expansions. Its current pipeline targets Friedreich's Ataxia (FA), a severe, progressive, monogenic, and autosomal recessive disease. FA primarily impairs mitochondrial function across various organ systems, resulting in neurological, cardiac, and metabolic complications. Another significant area of development is Myotonic Dystrophy Type-1 (DM1). This is a progressive, dominantly inherited monogenic neuromuscular illness that impacts skeletal muscle, the heart, brain, and other bodily systems. Beyond these, the company is advancing its GeneTAC product candidate platform to address an array of other monogenic conditions caused by nucleotide repeat expansions. These include Fragile X syndrome, various spinocerebellar ataxias, amyotrophic lateral sclerosis (ALS), frontotemporal dementia, Huntington's disease, and spinobulbar muscular atrophy. Established in 2017, Design Therapeutics, Inc. maintains its headquarters in Carlsbad, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD13.37 -0.30 (-2.18%)
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Volume Profile
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Liquidity & share structure
Average Volume
889.4K
Beta
1.66
Float Shares
35.36M
Free Float %
56.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-2.42% -4.64% -22.94% +0.38% +11.61% +11.73% +180.97% +74.96% -59.88% -74.74% -74.74%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (7 ratings, all time) Buy
Price Targets & DCF
Current price
13.37
Low 14.00 +4.7%
Consensus 17.50 +30.9%
Median 17.50 +30.9%
High 21.00 +57.0%
DCF (Unlevered) 0.27 -98.0%
DCF (Levered) 0.28 -97.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 2 0
Buy 5 +1
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
21.00
+57.0%
Last Quarter 2
20.50
+53.3%
Last Year 5
17.60
+31.6%
All Time 10
18.90
+41.3%
Quality scores
Altman Z-Score
29.86
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    -38.6% Q1'26: +6.5% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q1'26: +3,873.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +1.3% Q1'26: +8.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: -0.03× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.74) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.27 Current price: 13.37
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
5 EPS Ana.
Dec 2027
7 Rev. Ana.
5 EPS Ana.
Dec 2028
6 Rev. Ana.
5 EPS Ana.
Dec 2029
5 Rev. Ana.
1 EPS Ana.
Dec 2030
3 Rev. Ana.
1 EPS Ana.
Revenue
est: 48.53M (-100.0%)
117.33M
117.33M – 117.33M
+141.8% YoY
204.78M
204.78M – 204.78M
+74.5% YoY
8.40M
8.40M – 8.40M
-95.9% YoY
72.09M
72.09M – 72.09M
+758.2% YoY
235.57M
235.57M – 235.57M
+226.8% YoY
EBITDA
-48.99M
-78.85M
— – —
— – —
— – —
— – —
— – —
EBIT
-49.59M
-79.47M
— – —
— – —
— – —
— – —
— – —
Net Income
-49.59M
est: -50.93M (+2.6%)
-69.79M
est: -74.36M (+6.1%)
-85.49M
-93.45M – -67.08M
-15.0% YoY
-94.60M
-112.53M – -76.68M
-10.7% YoY
-109.43M
-138.13M – -80.73M
-15.7% YoY
-86.28M
-86.28M – -86.28M
+21.2% YoY
-2.96M
-2.96M – -2.96M
+96.6% YoY
SGA
18.03M
20.34M
— – —
— – —
— – —
— – —
— – —
EPS
-0.88
est: -0.90 (+2.2%)
-1.22
est: -1.30 (+6.3%)
-1.36
-1.63 – -1.17
-4.5% YoY
-1.64
-1.96 – -1.34
-20.3% YoY
-1.95
-2.41 – -1.41
-19.3% YoY
-1.51
-1.51 – -1.51
+22.9% YoY
-0.05
-0.05 – -0.05
+96.6% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-04 Oppenheimer Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-28 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-27 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-26 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-22 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-21 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-20 C+ 2/5 3/5 1/5 1/5 4/5 1/5 2/5
2026-05-19 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-18 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-15 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-14 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-13 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-12 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-11 C 2/5 2/5 1/5 1/5 4/5 1/5 2/5
2026-05-08 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-24 C 2/5 2/5 1/5 1/5 3/5 1/5 3/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 3/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-53.90M
OE per share TTM
-0.92
Owner's Yield
-8.37%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
2,569,065.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
124
Total invested
404.11M
Insider transactions (90d)
0
Beneficial owners (>5%)
22
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 of 5 Pages 7.67M 13.80% 7.67M IN 2022-02-09
2 Simeon George 5.64M 10.50% 15.0K 5.63M 15.0K 5.63M IN 2021-04-09
3 LLC 5.63M 10.50% 5.63M 5.63M HC 2021-04-09
4 LP 5.63M 10.50% 5.63M 5.63M PN 2021-04-09
5 Bihua Chen 5.11M 9.20% 5.11M IN Cayman Islands 2021-04-09
6 Cormorant Asset Management, LP 5.11M 9.20% 5.11M PN Cayman Islands 2021-04-09
7 Jason Howerton 3.83M 6.90% 3.83M 3.83M IN United States 2022-02-09
8 Light Irrevocable Trust #1 dated April 22, 2019 3.83M 6.90% 3.83M 3.83M OO United States 2022-02-09
9 (1) BlackRock, Inc. 3.51M 6.30% 3.46M 3.51M HC Delaware 2023-02-03
10 STATE STREET CORPORATION 3.04M 5.43% 3.00M 3.04M HC BOSTON, MASSACHUSETTS 2023-02-08
11 Peter Kolchinsky 2.97M 5.32% 2.97M HC, IN United States of America 2022-10-13
12 RA Capital Healthcare Fund, L.P. 2.97M 5.32% 2.97M PN Delaware 2022-10-13
13 RA Capital Management, L.P. 2.97M 5.32% 2.97M IA, PN Delaware 2022-10-13
14 Rajeev Shah 2.97M 5.32% 2.97M HC, IN United States of America 2022-10-13
15 Cormorant Private Healthcare Fund II, LP 2.34M 4.20% 2.34M PN Cayman Islands 2021-04-09
16 Cormorant Private Healthcare GP II, LLC 2.34M 4.20% 2.34M OO Cayman Islands 2021-04-09
17 Cormorant Global Healthcare GP, LLC 1.60M 2.88% 1.60M OO Cayman Islands 2021-04-09
18 Cormorant Global Healthcare Master Fund, LP 1.60M 2.88% 1.60M PN Cayman Islands 2021-04-09
19 Cormorant Private Healthcare Fund III, LP 1.08M 1.95% 1.08M PN Cayman Islands 2021-04-09
20 Cormorant Private Healthcare GP III, LLC 1.08M 1.95% 1.08M OO Cayman Islands 2021-04-09
21 2. 10.00 4.60% 2.58M IA, HC, OO Delaware 2023-04-03
22 Citadel Advisors Holdings LP 6.00 4.40% 2.71M 2.71M HC, PN U.S. Citizen 2022-12-22

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
124
+6 vs prev Q
New positions
21
Closed positions
14
Increased
78
Reduced
28
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 207.9K +207.9K (+100.0%) 1.95B +2.0B (+100.0%) 0.37% +0.365 pp 0.58% +0.576 pp USD9.38 +0.0% 1 qtrs NEW
2 SR ONE CAPITAL MANAGEMENT, LP 6.53M +— (+0.0%) 61.22M +12.1M (+24.6%) 11.46% -0.019 pp 8.67% +1.559 pp USD19.87 -52.8% 17 qtrs
3 POINT72 ASSET MANAGEMENT, L.P. 5.37M +2.0M (+60.8%) 50.39M +25.2M (+100.3%) 9.43% +3.558 pp 0.06% +0.014 pp USD7.24 +29.6% 12 qtrs
4 LOGOS GLOBAL MANAGEMENT LP 2.50M -1.2M (-31.6%) 23.45M -4.1M (-14.8%) 4.39% -2.038 pp 1.42% -1.050 pp USD17.48 -46.3% 20 qtrs
5 BAKER BROS. ADVISORS LP 2.23M +520.2K (+30.4%) 20.95M +8.0M (+62.4%) 3.92% +0.909 pp 0.12% +0.029 pp USD10.25 -8.5% 20 qtrs
6 BLACKROCK, INC. 2.12M +72.8K (+3.6%) 19.86M +4.5M (+29.0%) 3.72% +0.122 pp 0.00% +0.000 pp USD5.58 +68.1% 6 qtrs
7 VANGUARD GROUP INC 1.63M +187.2K (+13.0%) 15.30M +4.4M (+40.7%) 2.86% +0.325 pp 0.00% +0.000 pp USD14.33 -34.5% 20 qtrs
8 VIVO CAPITAL, LLC 1.61M +1.6M (+100.0%) 15.13M +15.1M (+100.0%) 2.83% +2.832 pp 0.98% +0.978 pp USD9.38 +0.0% 1 qtrs NEW
9 ALMITAS CAPITAL LLC 1.53M +— (+0.0%) 14.36M +2.8M (+24.6%) 2.69% -0.004 pp 3.16% +0.523 pp USD3.00 +212.7% 9 qtrs
10 RA CAPITAL MANAGEMENT, L.P. 1.46M +985.7K (+207.2%) 13.71M +10.1M (+282.7%) 2.57% +1.729 pp 0.14% +0.096 pp USD8.78 +6.8% 2 qtrs
11 DRIEHAUS CAPITAL MANAGEMENT LLC 1.18M +103.6K (+9.6%) 11.07M +3.0M (+36.6%) 2.07% +0.179 pp 0.08% +0.017 pp USD5.80 +61.7% 5 qtrs
12 WOODLINE PARTNERS LP 944.0K +331.3K (+54.1%) 8.86M +4.2M (+91.9%) 1.66% +0.580 pp 0.03% +0.013 pp USD5.74 +63.4% 4 qtrs
13 KYNAM CAPITAL MANAGEMENT, LP 784.6K -245.0K (-23.8%) 7.36M -393.1K (-5.1%) 1.38% -0.433 pp 0.47% -0.107 pp USD3.80 +146.8% 4 qtrs
14 FMR LLC 771.3K +30.4K (+4.1%) 7.23M +1.7M (+29.7%) 1.35% +0.051 pp 0.00% +0.000 pp USD7.20 +30.3% 20 qtrs
15 MORGAN STANLEY 702.3K +526.3K (+299.1%) 6.59M +5.3M (+397.1%) 1.23% +0.924 pp 0.00% +0.000 pp USD8.19 +14.5% 19 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 679.6K -16.0K (-2.3%) 6.38M +1.1M (+21.7%) 1.19% -0.030 pp 0.00% +0.000 pp USD15.27 -38.6% 20 qtrs
17 STATE STREET CORP 647.6K +13.2K (+2.1%) 6.07M +1.3M (+27.2%) 1.14% +0.022 pp 0.00% +0.000 pp USD10.60 -11.5% 19 qtrs
18 ACADIAN ASSET MANAGEMENT LLC 612.8K -4.7K (-0.8%) 5.74M +1.1M (+23.5%) 1.08% -0.010 pp 0.01% +0.001 pp USD3.41 +175.1% 9 qtrs
19 FRAZIER LIFE SCIENCES MANAGEMENT, L.P. 521.0K -1.4M (-73.3%) 4.89M -9.8M (-66.8%) 0.91% -2.521 pp 0.13% -0.310 pp USD4.10 +128.8% 7 qtrs
20 CAPTION MANAGEMENT, LLC 500.0K +500.0K (+100.0%) 4.69M +4.7M (+100.0%) 0.88% +0.878 pp 0.03% +0.032 pp USD9.38 +0.0% 1 qtrs NEW
21 CITADEL ADVISORS LLC 459.9K -94.1K (-17.0%) 4.31M +141.8K (+3.4%) 0.81% -0.167 pp 0.00% +0.000 pp USD12.24 -23.4% 20 qtrs
22 D. E. SHAW & CO., INC. 438.9K +65.6K (+17.6%) 4.12M +1.3M (+46.5%) 0.77% +0.114 pp 0.00% +0.001 pp USD4.29 +118.6% 12 qtrs
23 INVESCO LTD. 305.8K +291.2K (+1,995.8%) 2.87M +2.8M (+2,510.7%) 0.54% +0.511 pp 0.00% +0.000 pp USD9.20 +2.0% 5 qtrs
24 DIMENSIONAL FUND ADVISORS LP 297.9K +18.1K (+6.5%) 2.80M +690.1K (+32.8%) 0.52% +0.031 pp 0.00% +0.000 pp USD6.13 +53.0% 15 qtrs
25 RENAISSANCE TECHNOLOGIES LLC 287.1K +12.8K (+4.7%) 2.69M +627.5K (+30.4%) 0.50% +0.022 pp 0.00% +0.002 pp USD3.49 +168.8% 12 qtrs
26 NORTHERN TRUST CORP 286.6K -10.0K (-3.4%) 2.69M +455.2K (+20.4%) 0.50% -0.018 pp 0.00% +0.000 pp USD14.04 -33.2% 19 qtrs
27 GOLDMAN SACHS GROUP INC 270.7K +9.2K (+3.5%) 2.54M +570.1K (+29.0%) 0.48% +0.015 pp 0.00% +0.000 pp USD6.61 +41.9% 20 qtrs
28 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 236.9K -11.1K (-4.5%) 2.22M +354.8K (+19.0%) 0.42% -0.020 pp 0.00% +0.000 pp USD13.72 -31.6% 19 qtrs
29 JANE STREET GROUP, LLC 226.5K +108.7K (+92.2%) 2.12M +1.2M (+139.5%) 0.40% +0.191 pp 0.00% +0.000 pp USD7.89 +18.9% 12 qtrs
30 MARSHALL WACE, LLP 225.5K +225.5K (+100.0%) 2.12M +2.1M (+100.0%) 0.40% +0.396 pp 0.00% +0.002 pp USD9.38 +0.0% 1 qtrs NEW
31 JACOBS LEVY EQUITY MANAGEMENT, INC 194.6K +194.6K (+100.0%) 1.83M +1.8M (+100.0%) 0.34% +0.342 pp 0.01% +0.007 pp USD9.38 +0.0% 11 qtrs
32 ALGERT GLOBAL LLC 187.8K +187.8K (+100.0%) 1.76M +1.8M (+100.0%) 0.33% +0.330 pp 0.03% +0.028 pp USD9.38 +0.0% 1 qtrs NEW
33 MILLENNIUM MANAGEMENT LLC 180.9K +112.0K (+162.8%) 1.70M +1.2M (+227.4%) 0.32% +0.197 pp 0.00% +0.001 pp USD8.68 +8.1% 14 qtrs
34 AMERIPRISE FINANCIAL INC 158.4K +158.4K (+100.0%) 1.49M +1.5M (+100.0%) 0.28% +0.278 pp 0.00% +0.000 pp USD9.38 +0.0% 1 qtrs NEW
35 ACUTA CAPITAL PARTNERS, LLC 150.9K +150.9K (+100.0%) 1.42M +1.4M (+100.0%) 0.27% +0.265 pp 0.96% +0.961 pp USD9.38 +0.0% 1 qtrs NEW
36 NUVEEN, LLC 125.3K -7.8K (-5.8%) 1.17M +173.2K (+17.3%) 0.22% -0.014 pp 0.00% +0.000 pp USD3.86 +143.0% 4 qtrs
37 RAYMOND JAMES FINANCIAL INC 109.8K +109.8K (+100.0%) 1.03M +1.0M (+100.0%) 0.19% +0.193 pp 0.00% +0.000 pp USD9.38 +0.0% 1 qtrs NEW
38 DIADEMA PARTNERS LP 100.3K +100.3K (+100.0%) 941.0K +941.0K (+100.0%) 0.18% +0.176 pp 0.16% +0.162 pp USD9.38 +0.0% 1 qtrs NEW
39 TREXQUANT INVESTMENT LP 100.0K +100.0K (+100.0%) 937.7K +937.7K (+100.0%) 0.18% +0.176 pp 0.01% +0.008 pp USD9.38 +0.0% 1 qtrs NEW
40 BNP PARIBAS ARBITRAGE, SNC 94.8K +89.7K (+1,747.4%) 889.5K +850.8K (+2,201.3%) 0.17% +0.158 pp 0.00% +0.000 pp USD9.20 +2.0% 5 qtrs
41 BARCLAYS PLC 87.1K -9.6K (-9.9%) 816.6K +296.7K (+57.1%) 0.15% -0.017 pp 0.00% +0.000 pp USD4.07 +130.5% 16 qtrs
42 BANK OF NEW YORK MELLON CORP 85.0K -2.5K (-2.9%) 797.1K +138.4K (+21.0%) 0.15% -0.005 pp 0.00% +0.000 pp USD17.85 -47.5% 19 qtrs
43 EAM INVESTORS, LLC 78.9K +78.9K (+100.0%) 740.5K +740.5K (+100.0%) 0.14% +0.139 pp 0.08% +0.083 pp USD9.38 +0.0% 1 qtrs NEW
44 BRIDGEWAY CAPITAL MANAGEMENT, LLC 78.5K -109.7K (-58.3%) 736.3K -680.8K (-48.0%) 0.14% -0.193 pp 0.02% -0.015 pp USD3.01 +211.6% 10 qtrs
45 LYNX1 CAPITAL MANAGEMENT LP 69.5K +3.6K (+5.4%) 652.1K +155.4K (+31.3%) 0.12% +0.006 pp 0.13% +0.031 pp USD4.14 +126.6% 4 qtrs
46 PALUMBO WEALTH MANAGEMENT LLC 69.4K +17.3K (+33.2%) 650.8K +258.6K (+65.9%) 0.12% +0.030 pp 0.16% +0.035 pp USD5.72 +64.0% 8 qtrs
47 SUSQUEHANNA INTERNATIONAL GROUP, LLP 61.9K +47.8K (+341.1%) 580.2K +474.6K (+449.4%) 0.11% +0.084 pp 0.00% +0.000 pp USD8.58 +9.3% 15 qtrs
48 AMERICAN CENTURY COMPANIES INC 57.8K +6.9K (+13.7%) 542.1K +159.2K (+41.6%) 0.10% +0.012 pp 0.00% +0.000 pp USD5.12 +83.2% 7 qtrs
49 CANADA PENSION PLAN INVESTMENT BOARD 54.6K +54.6K (+100.0%) 512.1K +512.1K (+100.0%) 0.10% +0.096 pp 0.00% +0.000 pp USD9.38 +0.0% 1 qtrs NEW
50 SEI INVESTMENTS CO 52.7K +52.7K (+100.0%) 494.6K +494.6K (+100.0%) 0.09% +0.093 pp 0.00% +0.001 pp USD9.38 +0.0% 1 qtrs NEW
51 STATE OF WISCONSIN INVESTMENT BOARD 50.7K +23.6K (+87.2%) 475.2K +271.4K (+133.2%) 0.09% +0.041 pp 0.00% +0.001 pp USD6.37 +47.3% 4 qtrs
52 KENNEDY CAPITAL MANAGEMENT LLC 50.0K +20.6K (+70.1%) 469.2K +247.8K (+111.9%) 0.09% +0.036 pp 0.01% +0.005 pp USD7.84 +19.6% 5 qtrs
53 ALPS ADVISORS INC 46.8K +46.8K (+100.0%) 438.7K +438.7K (+100.0%) 0.08% +0.082 pp 0.00% +0.003 pp USD9.38 +0.0% 1 qtrs NEW
54 TWO SIGMA INVESTMENTS, LP 46.2K -13.0K (-21.9%) 433.7K -12.4K (-2.8%) 0.08% -0.023 pp 0.00% 0.000 pp USD3.25 +188.6% 13 qtrs
55 SQUAREPOINT OPS LLC 46.1K +46.1K (+100.0%) 432.8K +432.8K (+100.0%) 0.08% +0.081 pp 0.00% +0.001 pp USD9.38 +0.0% 1 qtrs NEW
56 ALLIANCEBERNSTEIN L.P. 46.1K +— (+0.0%) 432.6K +85.3K (+24.6%) 0.08% 0.000 pp 0.00% +0.000 pp USD9.89 -5.2% 15 qtrs
57 PRUDENTIAL FINANCIAL INC 42.7K -2.1K (-4.7%) 400.6K +63.1K (+18.7%) 0.08% -0.004 pp 0.00% +0.000 pp USD4.45 +110.8% 11 qtrs
58 XTX TOPCO LTD 35.3K +23.4K (+197.3%) 331.0K +241.6K (+270.3%) 0.06% +0.041 pp 0.01% +0.004 pp USD8.76 +7.1% 2 qtrs
59 PERSISTENT ASSET PARTNERS LTD 35.0K +35.0K (+100.0%) 328.2K +328.2K (+100.0%) 0.06% +0.061 pp 0.15% +0.147 pp USD9.38 +0.0% 1 qtrs NEW
60 RHUMBLINE ADVISERS 34.8K -11.6K (-24.9%) 326.2K -22.7K (-6.5%) 0.06% -0.020 pp 0.00% +0.000 pp USD14.69 -36.1% 18 qtrs
61 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 34.3K -700.0 (-2.0%) 321.6K +58.2K (+22.1%) 0.06% -0.001 pp 0.02% +0.003 pp USD7.08 +32.5% 5 qtrs
62 BANK OF AMERICA CORP /DE/ 27.4K +3.5K (+14.8%) 257.4K +77.4K (+43.0%) 0.05% +0.006 pp 0.00% +0.000 pp USD6.85 +36.9% 20 qtrs
63 CI PRIVATE WEALTH, LLC 27.0K +27.0K (+100.0%) 252.9K +252.9K (+100.0%) 0.05% +0.047 pp 0.00% +0.000 pp USD9.38 +0.0% 8 qtrs
64 WELLS FARGO & COMPANY/MN 26.8K +8.5K (+46.2%) 251.3K +113.3K (+82.2%) 0.05% +0.015 pp 0.00% +0.000 pp USD6.40 +46.6% 17 qtrs
65 UBS GROUP AG 25.5K +2.8K (+12.5%) 239.5K +68.7K (+40.2%) 0.04% +0.005 pp 0.00% +0.000 pp USD6.12 +53.3% 13 qtrs
66 TWO SIGMA ADVISERS, LP 25.3K -15.2K (-37.5%) 237.3K -67.7K (-22.2%) 0.04% -0.027 pp 0.00% 0.000 pp USD3.08 +204.5% 12 qtrs
67 RUSSELL INVESTMENTS GROUP, LTD. 25.2K +18.9K (+295.7%) 236.7K +188.7K (+392.9%) 0.04% +0.033 pp 0.00% +0.000 pp USD8.38 +11.9% 15 qtrs
68 STRS OHIO 25.2K +2.6K (+11.5%) 236.4K +66.2K (+38.9%) 0.04% +0.005 pp 0.00% +0.000 pp USD3.17 +195.9% 10 qtrs
69 VIRTU FINANCIAL LLC 22.7K +22.7K (+100.0%) 212.0K +212.0K (+100.0%) 0.04% +0.040 pp 0.01% +0.008 pp USD9.38 +0.0% 1 qtrs NEW
70 ALPHACENTRIC ADVISORS LLC 20.3K +20.3K (+100.0%) 190.1K +190.1K (+100.0%) 0.04% +0.036 pp 0.19% +0.189 pp USD9.38 +0.0% 1 qtrs NEW
71 VELAN CAPITAL INVESTMENT MANAGEMENT LP 20.0K +— (+0.0%) 187.6K +37.0K (+24.6%) 0.04% 0.000 pp 0.11% -0.033 pp USD3.71 +152.8% 4 qtrs
72 BAADER BANK AKTIENGESELLSCHAFT 20.0K +20.0K (+100.0%) 187.6K +187.6K (+100.0%) 0.04% +0.035 pp 0.01% +0.013 pp USD9.38 +0.0% 1 qtrs NEW
73 PRICE T ROWE ASSOCIATES INC /MD/ 15.7K -603.0 (-3.7%) 148.0K +25.0K (+20.3%) 0.03% -0.001 pp 0.00% +0.000 pp USD4.17 +124.9% 8 qtrs
74 DEUTSCHE BANK AG\ 15.5K +15.5K (+100.0%) 145.8K +145.8K (+100.0%) 0.03% +0.027 pp 0.00% +0.000 pp USD9.38 +0.0% 19 qtrs
75 METLIFE INVESTMENT MANAGEMENT, LLC 15.2K +4.9K (+47.8%) 143.0K +65.3K (+84.1%) 0.03% +0.009 pp 0.00% +0.000 pp USD8.13 +15.4% 6 qtrs
76 JPMORGAN CHASE & CO 14.5K -8.8K (-37.8%) 135.6K -39.3K (-22.5%) 0.03% -0.016 pp 0.00% +0.000 pp USD6.73 +39.4% 19 qtrs
77 ENGINEERS GATE MANAGER LP 14.0K +14.0K (+100.0%) 131.4K +131.4K (+100.0%) 0.02% +0.025 pp 0.00% +0.002 pp USD9.38 +0.0% 1 qtrs NEW
78 AQR CAPITAL MANAGEMENT LLC 13.7K +66.0 (+0.5%) 128.8K +25.9K (+25.2%) 0.02% +0.000 pp 0.00% +0.000 pp USD4.86 +93.0% 9 qtrs
79 MARINER, LLC 12.8K -3.3K (-20.3%) 120.0K -1.1K (-0.9%) 0.02% -0.006 pp 0.00% +0.000 pp USD4.10 +128.8% 8 qtrs
80 NISA INVESTMENT ADVISORS, LLC 11.8K +— (+0.0%) 110.9K +21.9K (+24.6%) 0.02% +0.000 pp 0.00% +0.000 pp USD2.68 +250.0% 10 qtrs
81 AXQ CAPITAL, LP 11.7K +11.7K (+100.0%) 110.0K +110.0K (+100.0%) 0.02% +0.021 pp 0.02% +0.025 pp USD9.38 +0.0% 1 qtrs NEW
82 TWO SIGMA SECURITIES, LLC 11.4K +11.4K (+100.0%) 106.9K +106.9K (+100.0%) 0.02% +0.020 pp 0.01% +0.015 pp USD9.38 +0.0% 1 qtrs NEW
83 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 11.1K +367.0 (+3.4%) 104.0K +23.3K (+28.8%) 0.02% +0.001 pp 0.00% +0.000 pp USD3.69 +154.2% 7 qtrs
84 PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO 7.1K +7.1K (+100.0%) 66.5K +66.5K (+100.0%) 0.01% +0.013 pp 0.00% +0.000 pp USD9.38 +0.0% 1 qtrs NEW
85 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 6.6K +— (+0.0%) 61.9K +12.2K (+24.6%) 0.01% +0.000 pp 0.00% +0.000 pp USD6.17 +52.0% 5 qtrs
86 TOWER RESEARCH CAPITAL LLC (TRC) 4.3K +2.3K (+118.1%) 40.1K +25.3K (+171.7%) 0.01% +0.004 pp 0.00% +0.001 pp USD6.80 +37.9% 20 qtrs
87 CAZ INVESTMENTS LP 3.5K -1.5K (-30.0%) 32.8K -4.8K (-12.8%) 0.01% -0.003 pp 0.06% -0.013 pp USD3.25 +188.6% 7 qtrs
88 CITIGROUP INC 3.1K +1.5K (+95.8%) 29.2K +17.2K (+143.9%) 0.01% +0.003 pp 0.00% +0.000 pp USD7.09 +32.3% 19 qtrs
89 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 2.8K +566.0 (+25.7%) 26.0K +9.4K (+56.6%) 0.00% +0.001 pp 0.00% +0.000 pp USD6.52 +43.9% 5 qtrs
90 AMERITAS INVESTMENT PARTNERS, INC. 2.6K +— (+0.0%) 24.1K +4.8K (+24.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD19.84 -52.7% 19 qtrs
91 LEGAL & GENERAL GROUP PLC 2.1K +— (+0.0%) 19.5K +3.8K (+24.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD19.73 -52.5% 20 qtrs
92 NEW YORK STATE COMMON RETIREMENT FUND 2.0K +— (+0.0%) 19.0K +3.7K (+24.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD17.45 -46.2% 19 qtrs
93 PNC FINANCIAL SERVICES GROUP, INC. 1.8K -7.0 (-0.4%) 17.0K +3.3K (+24.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD4.14 +126.6% 9 qtrs
94 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 1.5K -498.0 (-25.3%) 13.8K -1.0K (-6.9%) 0.00% -0.001 pp 0.00% +0.000 pp USD7.53 +24.6% 19 qtrs
95 STERLING CAPITAL MANAGEMENT LLC 1.4K -271.0 (-16.4%) 12.9K +507.0 (+4.1%) 0.00% -0.001 pp 0.00% +0.000 pp USD6.30 +48.9% 6 qtrs
96 ZURCHER KANTONALBANK (ZURICH CANTONALBANK) 1.2K +— (+0.0%) 11.5K +2.3K (+24.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD3.86 +143.0% 4 qtrs
97 GF FUND MANAGEMENT CO. LTD. 1.1K -95.0 (-7.8%) 10.5K +1.4K (+14.8%) 0.00% 0.000 pp 0.00% +0.000 pp USD5.75 +63.1% 5 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 66 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Virtus Biotech Clinical Trials ETF BBC 0.85% 490.6K 0.65%
2 iShares Genomics Immunology and Healthcare ETF IDNA 0.63% 1.23M 0.47%
3 ALPS Medical Breakthroughs ETF SBIO 0.49% 1.04M 0.50%
4 iShares Micro-Cap ETF IWC 0.11% 1.57M 0.60%
5 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.07% 49.9K 0.35%
6 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.07% 745.3K 0.35%
7 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.07% 301.8K 0.40%
8 Invesco Nasdaq Biotechnology ETF IBBQ 0.07% 48.7K 0.19%
9 Fidelity Enhanced Small Cap ETF FESM 0.05% 2.95M 0.28%
10 iShares Biotechnology ETF IBB 0.04% 4.11M 0.44%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
7
Sells
0
Shares acquired
1.64M
Shares disposed
Cash buys
Cash sales
Net activity
+1,637,500
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-03-31 Shapiro David Director A-Award A Stock option (right to buy) 60,000 10.64 638.4K 60,000 D
2026-01-02 Storgard Chris Officer A-Award A Stock option (right to buy) 250,000 9.10 2.28M 250,000 D
2026-01-02 Shah Pratik Director / Officer A-Award A Stock option (right to buy) 750,000 9.10 6.83M 750,000 D
2026-01-02 Jeffries Sean Officer A-Award A Stock option (right to buy) 375,000 9.10 3.41M 375,000 D
2026-01-02 Gover Justin D. Director A-Award A Stock option (right to buy) 45,000 9.10 409.5K 45,000 D
2026-01-02 Burgess Julie Officer A-Award A Stock option (right to buy) 150,000 9.10 1.37M 150,000 D
2025-12-09 Shah Pratik Director / Officer A-Award A Stock option (right to buy) 525,000 2.48 1.30M 525,000 D
2025-09-09 Gover Justin D. Director A-Award A Stock option (right to buy) 30,000 6.64 199.2K 30,000 D
2025-08-13 William Arsani Director S-Sale D Common Stock 345,000 5.25 1.81M 2,655,000 I
2025-06-10 William Arsani Director A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-06-10 Schmid John P. Director A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-06-10 Prasad Deepa Director A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-06-10 LAPPE RODNEY W Director A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-06-10 George Simeon Director / 10% Owner A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-06-10 Berger Heather A. Director A-Award A Stock Option (right to buy) 19,000 4.01 76.2K 19,000 D
2025-05-01 Storgard Chris Officer A-Award A Stock Option (right to buy) 400,000 4.71 1.88M 400,000 D
2025-04-16 Storgard Chris 0 0.00 0
2025-01-02 Shah Pratik Director / Officer A-Award A Stock option (right to buy) 600,000 6.17 3.70M 600,000 D
2025-01-02 LAPPE RODNEY W Director A-Award A Stock option (right to buy) 25,993 6.17 160.4K 25,993 D
2025-01-02 Jeffries Sean Officer A-Award A Stock option (right to buy) 260,000 6.17 1.60M 260,000 D
2025-01-02 Burgess Julie Officer A-Award A Stock option (right to buy) 135,000 6.17 833.0K 135,000 D
2024-12-18 Prasad Deepa Director S-Sale D Common Stock 3,806 6.27 23.9K 20,000 D
2024-10-01 DUNHAM TRUST Co 0 0.00 0
2024-08-09 William Arsani Director S-Sale D Common Stock 814,874 4.25 3.46M 0
2024-06-13 William Arsani Director A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-06-13 Schmid John P. Director A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-06-13 Prasad Deepa Director A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-06-13 LAPPE RODNEY W Director A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-06-13 George Simeon Director / 10% Owner A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-06-13 Berger Heather A. Director A-Award A Stock Option (right to buy) 19,000 3.82 72.6K 19,000
2024-03-25 Schmid John P. Director P-Purchase A Common Stock 17,809 3.74 66.6K 26,965
2024-03-25 Berger Heather A. Director P-Purchase A Common Stock 1,300 3.74 4.9K 1,300
2024-03-22 Schmid John P. Director P-Purchase A Common Stock 9,156 3.62 33.1K 9,156
2024-03-13 Kim Jae B. Officer D Stock Option (right to buy) 115,000 7.97 916.6K 0
2024-01-02 Jeffries Sean Officer A-Award A Stock Option (right to buy) 350,000 2.54 889.0K 350,000
2024-01-02 Burgess Julie Officer A-Award A Stock Option (right to buy) 110,000 2.54 279.4K 110,000
2023-12-01 LAPPE RODNEY W Director A-Award A Stock Option (right to buy) 69,186 2.51 173.7K 69,186
2023-12-01 Ansari Aseem Z. 10% Owner A-Award A Stock Option (right to buy) 100,000 2.51 251.0K 100,000
2023-09-29 LAPPE RODNEY W Director P-Purchase A Common Stock 21,000 2.35 49.3K 133,024
2023-09-01 Shah Pratik Director / Officer A-Award A Stock Option (right to buy) 1,050,000 2.48 2.60M 1,050,000
2023-08-29 William Arsani Director P-Purchase A Common Stock 1,960,000 2.44 4.78M 3,000,000
2023-08-29 Prasad Deepa Director P-Purchase A Common Stock 12,000 2.31 27.7K 23,806
2023-08-28 William Arsani Director P-Purchase A Common Stock 275,000 2.15 591.3K 1,040,000
2023-05-31 Xu Stella Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 William Arsani Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 Schmid John P. Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 Prasad Deepa Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 LAPPE RODNEY W Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 George Simeon Director / 10% Owner A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-05-31 Berger Heather A. Director A-Award A Stock Option (right to buy) 15,000 5.63 84.5K 15,000
2023-02-01 Siffert Joao MD Director / Officer A-Award A Stock Option (right to buy) 415,000 7.97 3.31M 415,000
2023-02-01 Shah Pratik Director / Officer A-Award A Stock Option (right to buy) 415,000 7.97 3.31M 415,000
2023-02-01 Jeffries Sean Officer A-Award A Stock Option (right to buy) 140,000 7.97 1.12M 140,000
2023-02-01 Burgess Julie Officer A-Award A Stock Option (right to buy) 75,000 7.97 597.8K 75,000
2022-12-20 Siffert Joao MD Officer P-Purchase A Common Stock 6,300 8.38 52.8K 132,619
2022-12-20 SR One Capital Fund I Aggregator LP Director P-Purchase A Common Stock 40,000 8.14 325.4K 6,526,476
2022-12-20 George Simeon Director P-Purchase A Common Stock 40,000 8.14 325.4K 6,526,476
2022-12-19 Siffert Joao MD Officer P-Purchase A Common Stock 1,150 8.47 9.7K 126,319
2022-12-19 SR One Capital Fund I Aggregator LP Director P-Purchase A Common Stock 360,000 8.63 3.11M 6,486,476
2022-12-19 George Simeon Director P-Purchase A Common Stock 360,000 8.63 3.11M 6,486,476
2022-12-16 SR One Capital Fund I Aggregator LP Director P-Purchase A Common Stock 500,000 8.28 4.14M 6,126,476
2022-12-16 George Simeon Director P-Purchase A Common Stock 500,000 8.28 4.14M 6,126,476
2022-12-09 LAPPE RODNEY W Director P-Purchase A Common Stock 15,000 7.96 119.4K 112,024
2022-06-15 Xu Stella Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 William Arsani Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 Schmid John P. Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 Prasad Deepa Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 LAPPE RODNEY W Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 George Simeon Director A-Award A Stock Option (right to buy) 15,000 0.00 15,000
2022-06-15 Berger Heather A. Director A-Award A Stock Option (right to buy) 15,000 13.69 205.4K 15,000
2022-03-21 William Arsani Director P-Purchase A Common Stock 25,000 18.99 474.7K 2,797,501
2022-03-18 Xu Stella Director S-Sale D Common Stock 13,200 20.34 268.5K 4,155,405
2022-03-16 Prasad Deepa Director J-Other A Common Stock 11,806 0.00 11,806
2022-02-01 Siffert Joao MD Director / Officer A-Award A Stock Option (right to buy) 475,000 12.77 6.07M 475,000
2022-02-01 Shah Pratik Director / Officer A-Award A Stock Option (right to buy) 475,000 12.77 6.07M 475,000
2022-02-01 Jeffries Sean Officer A-Award A Stock Option (right to buy) 350,000 12.77 4.47M 350,000
2022-02-01 Burgess Julie Officer A-Award A Stock Option (right to buy) 50,000 12.77 638.5K 50,000
2021-10-01 Burgess Julie Officer A-Award A Stock Option (right to buy) 135,000 14.99 2.02M 135,000
2021-09-13 Burgess Julie Officer 0 0.00 0
2021-08-31 William Arsani Director P-Purchase A Common Stock 40,000 15.45 618.0K 2,772,501
2021-08-13 Giangiulio Dawn Officer D Stock option (right to buy) 24,539 0.95 23.3K 0
2021-06-15 Prasad Deepa Director I Common Stock 0 0.00 337,327
2021-06-15 Behanna Heather Director A-Award A Stock Option (right to buy) 30,000 27.04 811.2K 30,000
2021-03-30 Xu Stella Director / 10% Owner C-Conversion D Series B Preferred Stock 458,016 0.00 0
2021-03-30 William Arsani Director P-Purchase A Common Stock 700,000 20.00 14.00M 2,732,501
2021-03-30 Thacker Justin Officer P-Purchase A Common Stock 17,500 20.00 350.0K 17,500
2021-03-30 Shah Pratik Officer C-Conversion A Common Stock 104,923 129,923
2021-03-30 SR One Capital Fund I Aggregator LP 10% Owner C-Conversion A Common Stock 4,439,839 0.00 4,439,839
2021-03-30 Quan Venture Fund II, L.P. 10% Owner C-Conversion A Common Stock 280,991 0.00 4,720,830
2021-03-30 LAPPE RODNEY W Director P-Purchase A Common Stock 5,000 20.00 100.0K 97,024
2021-03-30 Jeffries Sean Officer P-Purchase A Common Stock 3,050 20.00 61.0K 3,050
2021-03-30 George Simeon Director / 10% Owner C-Conversion D Series A Preferred Stock 7,236,938 0.00 0
2021-03-30 Cormorant Asset Management, LP P-Purchase A Common Stock 750,000 20.00 15.00M 5,114,844
2021-03-25 Xu Stella Director / 10% Owner I Series A Preferred Stock 4,439,839 0.00 0
2021-03-25 William Arsani Director I Series B Preferred Stock 814,874 0.00 0
2021-03-25 Thacker Justin Officer D Stock option (right to buy) 92,024 0.95 87.4K 0
2021-03-25 Star Irrevocable Trust #1 dated April 22, 2019 10% Owner D Common Stock 0 0.00 3,834,355
2021-03-25 Siffert Joao MD Director / Officer D Common Stock 0 0.00 122,699
2021-03-25 Shah Pratik Director / Officer I Series A Preferred Stock 104,923 0.00 0
2021-03-25 Schmid John P. Director D Common Stock 0 0.00 30,674
2021-03-25 SR One Capital Fund I Aggregator LP 10% Owner Series B Preferred Stock 936,637 0.00 0 D
2021-03-25 Light Irrevocable Trust #1 dated April 22, 2019 10% Owner D Common Stock 0 0.00 3,834,355
2021-03-25 LAPPE RODNEY W Director D Common Stock 0 0.00 92,024
2021-03-25 Jeffries Sean Officer D Common Stock 0 0.00 807,233
2021-03-25 George Simeon Director / 10% Owner I Series B Preferred Stock 936,637 0.00 0
2021-03-25 Cormorant Asset Management, LP 10% Owner I Series B Convertible Preferred Stock 1,404,953 0.00 0
2021-03-25 Ansari Aseem Z. 10% Owner D Common Stock 0 0.00 7,668,711
2020-10-12 Siffert Joao MD Director / Officer D Stock option (right to buy) 644,171 0.95 612.0K 0

Executive team

Top executives
Shares Outstanding
62.46M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Pratik Shah, Ph.D. President, Chief Executive Officer and Chairperson 395.0K 144.0K 2.75M 237.0K 14.0K 3.54M 77.71%
2 2025 Chris M. Storgard, M.D. Chief Medical Officer 339.3K 144.7K 1.40M 135.7K 14.0K 2.03M 68.81%
3 2025 Sean Jeffries, Ph.D. Chief Operating Officer 484.0K 6.4K 1.19M 193.6K 14.0K 1.89M 63.10%
4 2024 Sean Jeffries, Ph.D. Chief Operating Officer 432.7K 26.9K 668.5K 173.1K 13.9K 1.32M 50.84%
5 2024 Pratik Shah, Ph.D. President, Chief Executive Officer and Chairperson 395.0K 144.0K 237.0K 13.8K 789.8K 0.00%
6 2024 Jae B. Kim, M.D. Former Chief Medical Officer 362.7K 334.3K 13.7K 710.7K 47.03%
7 2023 Pratik Shah, Ph.D. President, Chief Executive Officer and Chairperson 360.6K 181.6K 5.61M 148.7K 13.2K 6.32M 88.86%
8 2023 João Siffert, M.D. Former President and Chief Executive Officer 431.4K 2.19M 893.9K 3.51M 62.27%
9 2023 Sean Jeffries, Ph.D. Chief Operating Officer 416.0K 729.6K 124.8K 13.2K 1.28M 56.84%
10 2022 João Siffert, M.D. Former President and Chief Executive Officer 577.5K 3.88M 288.8K 36.2K 4.78M 81.12%
11 2022 João Siffert, M.D. President and Chief Executive Officer 577.5K 3.88M 288.8K 36.2K 4.78M 81.12%
12 2022 Pratik Shah, Ph.D. Executive Chairperson 337.5K 120.0K 3.88M 168.8K 12.2K 4.52M 85.86%
13 2022 Pratik Shah, Ph.D. President, Chief Executive Officer and Chairperson 337.5K 120.0K 3.88M 168.8K 12.2K 4.52M 85.86%
14 2022 Sean Jeffries, Ph.D. Chief Operating Officer 400.0K 2.86M 160.0K 12.2K 3.43M 83.31%
15 2021 João Siffert, M.D. President and Chief Executive Officer 550.0K 150.0K 275.0K 18.0K 933.0K 0.00%
16 2021 Pratik Shah, Ph.D. Executive Chairperson 310.0K 120.0K 155.0K 585.0K 0.00%
17 2021 Sean Jeffries, Ph.D. Chief Operating Officer 340.0K 136.0K 476.0K 0.00%
18 2020 João Siffert, M.D. President and Chief Executive Officer 122.9K 4.23M 4.36M 97.18%
19 2020 Pratik Shah, Ph.D. Executive Chairperson 250.0K 150.0K 400.0K 0.00%
20 2020 Sean Jeffries, Ph.D. Chief Operating Officer 243.3K 100.0K 343.3K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2025-04-24 DEFA14A
2025-04-24 DEF 14A
2024-04-25 DEFA14A
2024-04-25 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-18 8-K
2026-05-15 SC 13G/A
2026-04-28 8-K
2026-04-28 10-Q
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2026-04-23 ARS
2026-04-01 8-K
2026-04-01 4
2026-04-01 3

Executive team

NameTitleCompensationGender
Pratik Shah Co-Founder, President, Chief Executive Officer, Principal Financial Officer & Executive Chairperson 790.0K male
Sean Jeffries Chief Operating Officer 698.0K
Chris Storgard Chief Medical Officer 633.8K
Jim Kerr Chief of Manufacturing & Product Development male
Julie D. Burgess Chief Accounting Officer female
Mustapha Parekh General Counsel male
Aseem Z. Ansari Co-Founder & Scientific Advisor
Tadimeti S. Rao Chief Scientific Officer
Chengzhi Zhang Chief Chemist
Doane Chilcoat Chief Technology Officer male
ESG Rating
B
BIOTECHNOLOGY
Rank: 557 out of 714
2026
E (Environmental)
59.0 / 56.3
Company / Sector avg.
S (Social)
59.9 / 62.4
Company / Sector avg.
G (Governance)
59.0 / 60.9
Company / Sector avg.
ESG Total
59.3 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits