Calidi Biotherapeutics, Inc. (CLDI)
San Diego, CA, US
Calidi Biotherapeutics, Inc. is a clinical-stage biotechnology company focused on immuno-oncology, dedicated to developing advanced immunotherapies for various cancers. The company's innovative approach centers on utilizing powerful, allogeneic (donor-derived) stem cells as specialized carriers for anti-tumor agents. This technology is being advanced to address a range of oncological conditions, including aggressive brain tumors (high-grade gliomas) and other solid malignancies. Calidi's proprietary cell-based delivery systems are expertly designed to safeguard, amplify, and boost the therapeutic effects of oncolytic viruses. This strategic delivery method aims to achieve superior treatment efficacy and enhance patient safety. The company's clinical pipeline features two primary candidates: NeuroNova, which employs allogeneic neural stem cells loaded with an oncolytic adenovirus specifically for the treatment of high-grade gliomas; and SuperNova, which utilizes allogeneic adipose-derived mesenchymal stem cells to deliver the tumor-selective CAL1 oncolytic vaccinia virus for advanced metastatic solid tumors. Established in 2014, Calidi Biotherapeutics operates out of San Diego, California.
Based on only 1 article — low confidence
No mergers or acquisitions recorded for this company.
| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -2.26% | -9.90% | -32.51% | -75.25% | -87.63% | -84.14% | -96.30% | -99.99% | -99.98% | -99.98% | -99.98% |
Revenue flow
Revenue by geography
Revenue by segment
Revenue composition
By product
By geography
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.
| Rating | 2025-10 | Change |
|---|---|---|
| Strong Buy | 0 | 0 |
| Buy | 1 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | — | — |
| Last Quarter | — | — |
| Last Year | — | — |
| All Time | 2 |
5.50
+4,464.3%
|
-
Revenue growth Biotechnology: +1.6%—
-
EPS growth Biotechnology: +29.7%+83.3% ★ Q1'26: +80.5% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%—
-
EBIT margin Biotechnology: +0.0%—
-
ROIC Biotechnology: -16.1%-2,799.5% Q1'26: +42,943.6% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+547.5% Q1'26: +358.5% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.14× Q1'26: -0.10× (vs Q1'25)
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
| Metric |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 1 EPS Ana. |
Dec 2027 1 EPS Ana. |
Dec 2028 1 Rev. Ana. 1 EPS Ana. |
|---|---|---|---|---|---|
| Revenue |
—
|
—
|
—
— – —
|
—
— – —
|
7.29M
7.29M – 7.29M
|
| EBITDA |
-19.73M
|
-18.59M
|
—
— – —
|
—
— – —
|
1.46M
1.46M – 1.46M
|
| EBIT |
-21.26M
|
-20.24M
|
—
— – —
|
—
— – —
|
1.46M
1.46M – 1.46M
|
| Net Income |
-22.14M
est: -29.46M (+24.8%)
|
-19.91M
est: -32.01M (+37.8%)
|
-23.75M
-23.75M – -23.75M
+25.8% YoY
|
-20.65M
-20.65M – -20.65M
+13.0% YoY
|
-20.13M
-20.13M – -20.13M
+2.5% YoY
|
| SGA |
12.90M
|
10.50M
|
—
— – —
|
—
— – —
|
531.19M
531.19M – 531.19M
|
| EPS |
-35.70
est: -44.34 (+19.5%)
|
-5.95
est: -7.44 (+20.0%)
|
-5.52
-5.52 – -5.52
+25.8% YoY
|
-4.80
-4.80 – -4.80
+13.0% YoY
|
-4.68
-4.68 – -4.68
+2.5% YoY
|
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-15 | B- | 3/5 | 5/5 | 1/5 | 1/5 | 2/5 | 1/5 | 5/5 |
| 2026-05-14 | B- | 3/5 | 5/5 | 1/5 | 1/5 | 2/5 | 1/5 | 5/5 |
| 2026-05-13 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 2/5 | 1/5 | 3/5 |
| 2026-05-12 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 2/5 | 1/5 | 3/5 |
| 2026-05-11 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 2/5 | 1/5 | 3/5 |
| 2026-05-08 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-05-07 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-05-06 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-05-05 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-05-04 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-05-01 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-30 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-29 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-28 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-27 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-24 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-23 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-22 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-21 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-20 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-17 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
| 2026-04-16 | C+ | 2/5 | 5/5 | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 |
Owner Earnings
Ownership Overview
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cable Car Capital LLC (3) | 897.2K | 9.99% | 897.2K | — | 897.2K | — | IA, PN | Delaware | 2024-09-11 | ↗ |
| 2 | Funicular Funds, LP | 897.2K | 9.99% | 897.2K | — | 897.2K | — | PN | Delaware | 2024-09-11 | ↗ |
| 3 | Jacob Ma-Weaver (3) | 897.2K | 9.99% | 897.2K | — | 897.2K | — | IN | Delaware | 2024-09-11 | ↗ |
Institutional Activity (13F)
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | DRW SECURITIES, LLC | 147.8K +147.8K (+100.0%) | 172.9K +172.9K (+100.0%) | 3.01% +3.011 pp | 0.00% +0.005 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 2 | HIGHTOWER ADVISORS, LLC | 83.5K -1.4K (-1.7%) | 97.7K -31.4K (-24.3%) | 1.70% -0.029 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 3 | GEODE CAPITAL MANAGEMENT, LLC | 41.9K +12.3K (+41.7%) | 49.1K +4.1K (+9.1%) | 0.85% +0.251 pp | 0.00% +0.000 pp | USD1.42 -17.6% | 2 qtrs — |
| 4 | VANGUARD GROUP INC | 34.7K +— (+0.0%) | 40.6K -12.2K (-23.0%) | 0.71% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 5 | FMR LLC | 22.0K +21.9K (+17,510.4%) | 25.8K +25.6K (+13,455.3%) | 0.45% +0.446 pp | 0.00% +0.000 pp | USD1.17 +0.0% | 2 qtrs — |
| 6 | VIRTU FINANCIAL LLC | 21.2K +21.2K (+100.0%) | 25.0K +25.0K (+100.0%) | 0.43% +0.433 pp | 0.00% +0.001 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 7 | RS CRUM INC. | 20.3K +5.0K (+32.8%) | 23.7K +510.0 (+2.2%) | 0.41% +0.102 pp | 0.00% 0.000 pp | USD1.43 -18.2% | 2 qtrs — |
| 8 | NORTHERN TRUST CORP | 17.8K +17.8K (+100.0%) | 20.8K +20.8K (+100.0%) | 0.36% +0.362 pp | 0.00% +0.000 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 9 | JANE STREET GROUP, LLC | 11.5K +11.5K (+100.0%) | 13.4K +13.4K (+100.0%) | 0.23% +0.234 pp | 0.00% +0.000 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 10 | FARTHER FINANCE ADVISORS, LLC | 10.0K +10.0K (+100.0%) | 11.7K +11.7K (+100.0%) | 0.20% +0.204 pp | 0.00% +0.000 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 11 | UBS GROUP AG | 7.5K +5.0K (+193.1%) | 8.8K +4.9K (+125.6%) | 0.15% +0.101 pp | 0.00% +0.000 pp | USD1.29 -9.3% | 2 qtrs — |
| 12 | TOWER RESEARCH CAPITAL LLC (TRC) | 2.8K +2.8K (+100.0%) | 3.2K +3.2K (+100.0%) | 0.06% +0.057 pp | 0.00% +0.000 pp | USD1.17 +0.0% | 1 qtrs NEW |
| 13 | ADVISOR GROUP HOLDINGS, INC. | 2.1K +2.0K (+1,332.7%) | 2.5K +2.2K (+980.3%) | 0.04% +0.040 pp | 0.00% +0.000 pp | USD1.19 -1.7% | 2 qtrs — |
| 14 | MORGAN STANLEY | 1.5K +1.1K (+279.1%) | 1.7K +1.1K (+191.8%) | 0.03% +0.022 pp | 0.00% +0.000 pp | USD1.26 -7.1% | 2 qtrs — |
| 15 | FINEPOINT CAPITAL LP | 1.0K +— (+0.0%) | 1.2K -365.0 (-23.0%) | 0.02% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 16 | APOLLO MANAGEMENT HOLDINGS, L.P. | 1.0K +— (+0.0%) | 1.2K -364.0 (-23.0%) | 0.02% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 17 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 1.0K +— (+0.0%) | 1.2K -365.0 (-23.1%) | 0.02% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 18 | BARRETT & COMPANY, INC. | 292.00 +— (+0.0%) | 342.00 -102.0 (-23.0%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 19 | TRADEWINDS CAPITAL MANAGEMENT, LLC | 101.00 +— (+0.0%) | 119.00 -35.0 (-22.7%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.51 -22.5% | 2 qtrs — |
| 20 | REYES FINANCIAL ARCHITECTURE, INC. | 100.00 +— (+0.0%) | 117.00 -35.0 (-23.0%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.52 -23.0% | 2 qtrs — |
| 21 | SBI SECURITIES CO., LTD. | 46.00 +— (+0.0%) | 54.00 -16.0 (-22.9%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.50 -22.0% | 2 qtrs — |
| 22 | BANK OF AMERICA CORP /DE/ | 46.00 +16.0 (+53.3%) | 53.00 +7.0 (+15.2%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.37 -14.6% | 2 qtrs — |
| 23 | CVA FAMILY OFFICE, LLC | 42.00 +— (+0.0%) | 49.00 -15.0 (-23.4%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.50 -22.0% | 2 qtrs — |
| 24 | NORTHWESTERN MUTUAL WEALTH MANAGEMENT CO | 28.00 +28.0 (+100.0%) | 33.00 +33.0 (+100.0%) | 0.00% +0.001 pp | 0.00% +0.000 pp | USD1.14 +2.6% | 1 qtrs NEW |
| 25 | EVERMAY WEALTH MANAGEMENT LLC | 1.00 +— (+0.0%) | 2.00 +— (+0.0%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.00 +17.0% | 2 qtrs — |
| 26 | CITIGROUP INC | 1.00 +1.0 (+100.0%) | 1.00 +1.0 (+100.0%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.00 +17.0% | 1 qtrs NEW |
| 27 | WARBERG ASSET MANAGEMENT LLC | — -18.7K (-100.0%) | — -28.4K (-100.0%) | 0.00% -0.381 pp | 0.00% -0.005 pp | USD— | 2 qtrs SOLD |
| 28 | JPMORGAN CHASE & CO | — -9.0 (-100.0%) | — -14.0 (-100.0%) | 0.00% 0.000 pp | 0.00% +0.000 pp | USD— | 2 qtrs SOLD |
| 29 | ROYAL BANK OF CANADA | — -417.0 (-100.0%) | — -1.0K (-100.0%) | 0.00% -0.009 pp | 0.00% +0.000 pp | USD— | 2 qtrs SOLD |
| 30 | BELPOINTE ASSET MANAGEMENT LLC | — -20.8K (-100.0%) | — -31.6K (-100.0%) | 0.00% -0.424 pp | 0.00% -0.001 pp | USD— | 4 qtrs SOLD |
ETF Ownership
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | Vanguard Extended Market ETF VXF | 0.00% | 4.6K | 0.05% |
Insider Activity
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-12-12 | Camaisa Allan | Director | S-Sale | D | Common Stock | 850 | 1.46 | 1.2K | 76,952 | I | ↗ |
| 2025-09-03 | Poma Eric E | Officer | A-Award | A | Stock Options (right to buy) | 10,000 | 1.58 | 15.8K | 10,000 | D | ↗ |
| 2025-09-03 | Jackson Andrew C. | Officer | A-Award | A | Stock Options (right to buy) | 30,000 | 1.58 | 47.4K | 30,000 | D | ↗ |
| 2025-09-03 | Fernandez Santidrian Antonio | Officer | A-Award | A | Stock Options (right to buy) | 35,000 | 1.58 | 55.3K | 35,000 | D | ↗ |
| 2025-08-21 | Schoeneck James A | Director | P-Purchase | A | Warrant (right to buy) | 75,000 | 2.00 | 150.0K | 75,000 | D | ↗ |
| 2025-08-21 | Poma Eric E | Director / Officer | P-Purchase | A | Common Stock | 25,000 | 2.00 | 50.0K | 25,000 | D | ↗ |
| 2025-08-21 | Leftwich Scott | Director | P-Purchase | A | Warrant (right to buy) | 125,000 | 2.00 | 250.0K | 125,000 | D | ↗ |
| 2025-08-21 | Jackson Andrew C. | Officer | P-Purchase | A | Common Stock | 2,500 | 2.00 | 5.0K | 2,500 | D | ↗ |
| 2025-08-20 | Lincoln Alternative Strategies LLC | 10% Owner | — | — | Common Stock, par value $0.0001 per share | 0 | 0.00 | — | 730,000 | D | ↗ |
| 2025-07-09 | Stewart Alan R. | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 137,078 | 0.70 | 96.0K | 137,078 | D | ↗ |
| 2025-07-09 | Schoeneck James A | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 164,493 | 0.70 | 115.1K | 164,493 | D | ↗ |
| 2025-07-09 | Peoples George | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 137,078 | 0.70 | 96.0K | 137,078 | D | ↗ |
| 2025-07-09 | Leftwich Scott | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 137,078 | 0.70 | 96.0K | 137,078 | D | ↗ |
| 2025-04-22 | Poma Eric E | Director / Officer | A-Award | A | Stock Option (right to buy) | 726,412 | 0.47 | 340.7K | 726,412 | D | ↗ |
| 2024-12-31 | Stewart Alan R. | Director | A-Award | A | Common Stock | 12,771 | 0.00 | — | 28,976 | D | ↗ |
| 2024-12-31 | Leftwich Scott | Director | A-Award | A | Common Stock | 11,684 | 0.00 | — | 67,774 | D | ↗ |
| 2024-12-17 | Camaisa Allan | Director / Officer | S-Sale | D | Common Stock | 10,000 | 1.62 | 16.2K | 66,712 | D | ↗ |
| 2024-09-26 | Camaisa Allan | Director / Officer / 10% Owner | A-Award | A | Common Stock | 70,155 | 1.15 | 80.7K | 76,712 | D | ↗ |
| 2024-09-20 | Stewart Alan R. | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 20,217 | 1.09 | 22.0K | 20,217 | D | ↗ |
| 2024-09-20 | Schoeneck James A | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 20,217 | 1.09 | 22.0K | 20,217 | D | ↗ |
| 2024-09-20 | Peoples George | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 20,217 | 1.09 | 22.0K | 20,217 | D | ↗ |
| 2024-09-20 | Leftwich Scott | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 20,217 | 1.09 | 22.0K | 20,217 | D | ↗ |
| 2024-07-01 | Peoples George | Director | A-Award | A | Non-Qualified Stock Options (right to buy) | 30,904 | 0.19 | 6.0K | 30,904 | — | ↗ |
| 2024-06-28 | Stewart Alan R. | Director | A-Award | A | Common Stock | 73,437 | 0.00 | — | 154,087 | — | ↗ |
| 2024-06-28 | Schoeneck James A | Director | A-Award | A | Common Stock | 79,687 | 0.00 | — | 1,071,781 | — | ↗ |
| 2024-06-28 | Leftwich Scott | Director | A-Award | A | Common Stock | 67,187 | 0.00 | — | 560,873 | — | ↗ |
| 2024-06-17 | Minev Boris Radoslavov | Officer | A-Award | A | Stock Options (right to buy) | 31,360 | 0.20 | 6.1K | 31,360 | — | ↗ |
| 2024-06-17 | Jackson Andrew C. | Officer | A-Award | A | Stock Options (right to buy) | 300,000 | 0.20 | 58.5K | 300,000 | — | ↗ |
| 2024-06-17 | Campbell Wendy Pizarro | Officer | A-Award | A | Stock Options (right to buy) | 60,000 | 0.20 | 11.7K | 60,000 | — | ↗ |
| 2024-06-17 | Camaisa Allan | Director / Officer / 10% Owner | A-Award | A | Stock Options (right to buy) | 40,000 | 0.22 | 8.6K | 40,000 | — | ↗ |
| 2024-06-03 | Schoeneck James A | Director | A-Award | A | Warrants | 548,000 | 0.30 | 164.4K | 548,000 | — | ↗ |
| 2024-04-18 | Schoeneck James A | Director | A-Award | A | Common Stock | 375,000 | 0.40 | 150.0K | 415,887 | — | ↗ |
| 2024-03-29 | Stewart Alan R. | Director | A-Award | A | Common Stock | 25,995 | 0.00 | — | 80,650 | — | ↗ |
| 2024-03-29 | Schoeneck James A | Director | A-Award | A | Common Stock | 28,207 | 0.00 | — | 992,094 | — | ↗ |
| 2024-03-29 | Leftwich Scott | Director | A-Award | A | Common Stock | 23,783 | 0.00 | — | 493,686 | — | ↗ |
| 2024-01-01 | LaPre David | Director | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
Executive team
Executive compensation
Executive compensation not available.
No CEO compensation history available.
Proxy statements
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Eric E. Poma | Chief Executive Officer & Director | 565.6K | — |
| Andrew C. Jackson | Chief Financial Officer & Corporate Secretary | 557.6K | male |
| Antonio Fernandez Santidrian | Head of Technical Operations & Chief Scientific Officer | — | — |
| Guy Travis Clifton | Chief Medical Officer | — | male |
No Senate trading activity found for this company.
No House trading activity found for this company.
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Community Opinion for CLDI
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

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