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Compugen Ltd. (CGEN.TA)

ILA708.00 +15.00 (+2.16%)
IL TLV Healthcare Biotechnology
Address Azrieli Center 5885849
Holon, IL
CEO Eran Ophir
Website cgen.com
IPO 2002-08-12
ISIN IL0010852080

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Also trades on NASDAQ Global Market · CGEN (USD) Tel Aviv Stock Exchange · CGEN.TA (ILA)
Description

Compugen Ltd. is a clinical-stage biotechnology company engaged in the discovery, development, and commercialization of innovative therapeutic candidates across Israel, the United States, and Europe. The company's primary focus is immuno-oncology, with a robust pipeline of investigational treatments. Key assets in their immuno-oncology portfolio include: COM701, an anti-PVRIG antibody, currently in Phase I clinical trials for the treatment of solid tumors. COM902, a therapeutic antibody targeting TIGIT, also in Phase I, being evaluated as a monotherapy in patients with advanced malignancies. Bapotulimab, an antibody designed to target ILDR2, which is undergoing Phase I clinical study for solid tumors. AZD2936, a novel bispecific antibody that targets both TIGIT and PD-1, advancing through Phase I/II clinical studies in patients with advanced or metastatic non-small cell lung cancer. Beyond these clinical-stage programs, Compugen is also pursuing early-stage immuno-oncology research, with a particular emphasis on myeloid targets. The company maintains significant strategic alliances, including: A collaboration agreement with Bayer Pharma AG for the research, development, and commercialization of antibody-based therapeutics against Compugen's proprietary immune checkpoint regulators. A partnership with Bristol-Myers Squibb to assess the safety and tolerability of COM701 when combined with Bristol-Myers Squibb's PD-1 immune checkpoint inhibitor, Opdivo, in advanced solid tumor patients. An engagement with Johns Hopkins School of Medicine to explore novel T cell and myeloid checkpoint targets. A licensing agreement with AstraZeneca for the development of bispecific and multispecific immuno-oncology antibody products. A research collaboration with Johns Hopkins University focusing on myeloid research. Compugen Ltd. was founded in 1993 and is headquartered in Holon, Israel.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
ILA708.00 +15.00 (+2.16%)
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Volume Profile
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Liquidity & share structure
Average Volume
53.6K
Beta
2.74
Float Shares
92.49M
Free Float %
97.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-5.40% +4.30% -3.16% +58.79% +61.57% +77.69% +68.89% +199.68% -67.90% -68.24% +10.88%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (7 ratings, all time) Buy
Price Targets & DCF
Current price
708.00
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
5.35
Safe zone
Piotroski F-Score
5 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
A-
Overall Score
4 / 5
High
DCF Score
1 / 5
Low
ROE Score
5 / 5
High
ROA Score
5 / 5
High
D/E Score
3 / 5
Medium
P/E Score
3 / 5
Medium
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +161.1% Q1'26: -4.1% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +337.5% Q1'26: -6.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    +35.9% Q1'26: +0.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    +43.1% Q1'26: -414.4% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    Q1'26: +98.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +4.8% Q1'26: +2.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    0.09× Q1'26: -0.08× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.80) × ERP
WACC = 99% × Ke + 1% × Kd (4.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 708.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2021
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
5 Rev. Ana.
1 EPS Ana.
Dec 2027
5 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
2 Rev. Ana.
1 EPS Ana.
Dec 2030
2 Rev. Ana.
1 EPS Ana.
Revenue
9.28M
est: 5.40M (+71.9%)
712.0K
est: 749.3K (-5.0%)
est: 442.8K (-100.0%)
17.80M
est: 19.12M (-6.9%)
6.00M
est: 6.75M (-11.1%)
33.46M
est: 22.80M (+46.8%)
27.86M
est: 37.60M (-25.9%)
72.76M
est: 7.04M (+934.3%)
10.24M
10.24M – 10.24M
+45.5% YoY
24.68M
24.68M – 24.68M
+141.1% YoY
33.76M
33.76M – 33.76M
+36.8% YoY
31.19M
31.19M – 31.19M
-7.6% YoY
37.09M
37.09M – 37.09M
+18.9% YoY
EBITDA
-19.81M
est: -4.20M (-371.6%)
-31.10M
est: -583.1K (-5,233.6%)
-37.41M
est: -344.6K (-10,754.3%)
-21.83M
est: -14.88M (-46.7%)
-34.61M
est: -5.25M (-559.2%)
-12.52M
est: -17.74M (+29.4%)
-14.41M
est: -18.45M (+21.9%)
31.80M
est: -3.45M (+1,021.0%)
-5.02M
-5.02M – -5.02M
-45.5% YoY
-12.11M
-12.11M – -12.11M
-141.1% YoY
-16.57M
-16.57M – -16.57M
-36.8% YoY
-15.31M
-15.31M – -15.31M
+7.6% YoY
-18.20M
-18.20M – -18.20M
-18.9% YoY
EBIT
-20.92M
est: -4.24M (-393.9%)
-32.58M
est: -587.8K (-5,442.9%)
-37.41M
est: -347.4K (-10,666.7%)
-23.23M
est: -15.00M (-54.8%)
-35.07M
est: -5.29M (-562.5%)
-12.99M
est: -17.88M (+27.4%)
-14.89M
est: -18.74M (+20.5%)
31.33M
est: -3.51M (+993.4%)
-5.10M
-5.10M – -5.10M
-45.5% YoY
-12.30M
-12.30M – -12.30M
-141.1% YoY
-16.83M
-16.83M – -16.83M
-36.8% YoY
-15.55M
-15.55M – -15.55M
+7.6% YoY
-18.49M
-18.49M – -18.49M
-18.9% YoY
Net Income
-20.16M
est: -45.24M (+55.4%)
-31.51M
est: -55.75M (+43.5%)
-37.07M
est: -65.20M (+43.1%)
-22.60M
est: -41.84M (+46.0%)
-34.20M
est: -39.21M (+12.8%)
-18.75M
est: -17.41M (-7.7%)
-14.23M
est: -6.57M (-116.7%)
35.34M
est: -28.14M (+225.6%)
-21.24M
-21.24M – -21.24M
+24.5% YoY
-20.37M
-20.37M – -20.37M
+4.1% YoY
-21.03M
-21.03M – -21.03M
-3.2% YoY
-33.95M
-33.95M – -33.95M
-61.5% YoY
-30.00M
-30.00M – -30.00M
+11.6% YoY
SGA
7.32M
est: 10.20M (-28.2%)
8.52M
est: 1.42M (+502.1%)
8.82M
est: 836.6K (+954.6%)
9.68M
est: 36.13M (-73.2%)
11.70M
est: 12.75M (-8.2%)
9.98M
est: 43.06M (-76.8%)
10.02M
est: 31.86M (-68.6%)
9.43M
est: 5.96M (+58.2%)
8.67M
8.67M – 8.67M
+45.5% YoY
20.92M
20.92M – 20.92M
+141.1% YoY
28.61M
28.61M – 28.61M
+36.8% YoY
26.44M
26.44M – 26.44M
-7.6% YoY
31.43M
31.43M – 31.43M
+18.9% YoY
EPS
-0.40
est: -0.51 (+20.8%)
-0.62
est: -0.62 (+0.4%)
-0.72
est: -0.73 (+1.1%)
-0.41
est: -0.47 (+12.3%)
-0.41
est: -0.44 (+6.4%)
-0.21
est: -0.19 (-8.0%)
-0.16
est: -0.07 (-128.6%)
0.38
est: -0.30 (+226.7%)
-0.23
-0.23 – -0.23
+24.5% YoY
-0.22
-0.22 – -0.22
+4.1% YoY
-0.22
-0.22 – -0.22
-3.2% YoY
-0.36
-0.36 – -0.36
-61.5% YoY
-0.32
-0.32 – -0.32
+11.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-18 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-15 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-14 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-13 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-12 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-11 A- 4/5 1/5 5/5 5/5 3/5 3/5 4/5
2026-05-08 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-05-07 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-05-06 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-05-05 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-05-04 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-05-01 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-04-30 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-04-29 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-04-28 A 4/5 1/5 5/5 5/5 3/5 4/5 4/5
2026-04-27 A- 4/5 1/5 5/5 5/5 2/5 4/5 4/5
2026-04-24 A- 4/5 1/5 5/5 5/5 2/5 4/5 4/5
2026-04-23 A- 4/5 1/5 5/5 5/5 2/5 3/5 4/5
2026-04-20 A- 4/5 1/5 5/5 5/5 2/5 3/5 4/5
2026-04-17 A- 4/5 1/5 5/5 5/5 2/5 3/5 4/5
2026-04-16 A- 4/5 1/5 5/5 5/5 2/5 3/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-14.78M
OE per share TTM
-0.16
Owner's Yield
-1.97%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
17.9%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 3 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Avantis Responsible International Equity ETF AVSD 0.01% 36.5K 0.23%
2 Avantis Global Small Cap Value UCITS ETF AVGS.L 0.01% 67.8K 0.39%
3 Avantis International Small Cap Value ETF AVDV 0.00% 336.0K 0.36%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
423.3K
Shares Outstanding
94.55M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Anat Cohen-Dayag Executive Chair 743.1K
Michelle Mahler Chief Medical Officer 581.8K female
Pierre Ferre Chief Operating Officer 471.4K
Eran Ophir Chief Executive Officer, President & Director 312.2K
Zurit Levine Senior Vice President of Business Development 303.7K
David Silberman Chief Financial Officer male
Eran Ben Dor General Counsel & Corporate Secretary male
Rivka Schwartz Vice President Research and Discovery
Sharon Kredo-Russo Senior Vice President of Research & Discovery
Dorit Amitay Vice President of Human Resources female
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits