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C4 Therapeutics, Inc. (CCCC)

USD3.77 -0.04 (-1.02%)
US NASDAQ Healthcare Biotechnology
Address 490 Arsenal Way 2472
Watertown, MA, US
CEO Andrew J. Hirsch
IPO 2020-10-02
CIK 1662579 ISIN US12529R1077

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Description

C4 Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing innovative therapeutic candidates. Its core strategy involves degrading proteins implicated in disease, addressing a range of conditions including cancer, neurodegenerative disorders, and other illnesses. The company's primary drug candidate, CFT7455, is an orally administered MonoDAC degrader of the IKZF1 and IKZF3 proteins. This compound is currently undergoing Phase 1/2 clinical trials for the treatment of multiple myeloma and various non-Hodgkin lymphomas, such as peripheral T-cell lymphoma and mantle cell lymphoma. Additionally, C4 Therapeutics is advancing several other programs: CFT8634, an orally bioavailable BiDAC degrader targeting the BRD9 protein, for potential use in synovial sarcoma and SMARCB1-deleted solid tumors. CFT1946, an orally administered BiDAC degrader designed to act on the V600X mutant BRAF, aimed at indications like melanoma, non-small cell lung cancer (NSCLC), colorectal cancer, and other solid malignancies. CFT8919, an orally available, allosteric, and mutant-selective BiDAC degrader specifically targeting epidermal growth factor receptor (EGFR) with an L858R mutation in NSCLC. Their early-stage pipeline also features RET degraders for various forms of cancer. C4 Therapeutics, Inc. has formed strategic partnerships with F. Hoffmann-La Roche Ltd and Hoffmann-La Roche Inc., Biogen MA, Inc., and Calico Life Sciences LLC. The company was established in 2015 and its headquarters are located in Watertown, Massachusetts.

News Sentiment (7d)
50 Neutral

Based on only 1 article — low confidence

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD3.77 -0.04 (-1.02%)
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Volume Profile
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Liquidity & share structure
Average Volume
3M
Beta
2.93
Float Shares
70.28M
Free Float %
84.9%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% +8.93% +24.80% +73.22% +27.82% +65.97% +100.63% -2.76% -90.95% -87.56% -87.56%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (14 ratings, all time) Buy
Price Targets & DCF
Current price
3.77
Low 7.00 +85.6%
Consensus 7.00 +85.6%
Median 7.00 +85.6%
High 7.00 +85.6%
Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 7 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
7.00
+85.6%
Last Year 6
7.67
+103.4%
All Time 11
10.18
+170.0%
Quality scores
Altman Z-Score
-1.80
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +1.0% Q1'26: -100.0% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +16.5% Q1'26: +45.9% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -369.8%
  • EBIT margin Biotechnology: +0.0%
    -291.7%
  • ROIC Biotechnology: -16.1%
    -154.2% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +19.5% Q1'26: +78.0% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.58× Q1'26: -0.53× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (2.78) × ERP
WACC = 81% × Ke + 19% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 3.77
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
4 Rev. Ana.
4 EPS Ana.
Dec 2027
4 Rev. Ana.
4 EPS Ana.
Dec 2028
6 Rev. Ana.
6 EPS Ana.
Dec 2029
5 Rev. Ana.
4 EPS Ana.
Dec 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
33.20M
est: 32.92M (+0.8%)
45.79M
est: 33.08M (+38.4%)
31.10M
est: 39.80M (-21.9%)
20.76M
est: 29.38M (-29.3%)
35.58M
est: 35.79M (-0.6%)
35.95M
est: 30.36M (+18.4%)
21.62M
21.62M – 21.62M
-28.8% YoY
19.12M
19.12M – 19.12M
-11.6% YoY
17.28M
17.28M – 17.28M
-9.6% YoY
600.94M
600.94M – 600.94M
+3,377.0% YoY
1.97B
1.97B – 1.97B
+227.5% YoY
EBITDA
-58.83M
est: -32.92M (-78.7%)
-80.26M
est: -96.24M (+16.6%)
-124.28M
est: -113.31M (-9.7%)
-122.10M
est: -29.38M (-315.6%)
-103.37M
est: -35.79M (-188.8%)
-102.91M
est: -30.36M (-239.0%)
-21.62M
-21.62M – -21.62M
+28.8% YoY
-19.12M
-19.12M – -19.12M
+11.6% YoY
-17.28M
-17.28M – -17.28M
+9.6% YoY
-600.94M
-600.94M – -600.94M
-3,377.0% YoY
-1.97B
-1.97B – -1.97B
-227.5% YoY
EBIT
-60.45M
est: -32.92M (-83.6%)
-81.75M
est: -98.51M (+17.0%)
-125.96M
est: -116.26M (-8.3%)
-129.84M
est: -29.38M (-342.0%)
-105.19M
est: -35.79M (-193.9%)
-104.87M
est: -30.36M (-245.5%)
-21.62M
-21.62M – -21.62M
+28.8% YoY
-19.12M
-19.12M – -19.12M
+11.6% YoY
-17.28M
-17.28M – -17.28M
+9.6% YoY
-600.94M
-600.94M – -600.94M
-3,377.0% YoY
-1.97B
-1.97B – -1.97B
-227.5% YoY
Net Income
-66.33M
est: -550.98M (+88.0%)
-83.89M
est: -100.64M (+16.6%)
-128.18M
est: -117.73M (-8.9%)
-132.49M
est: -150.46M (+11.9%)
-105.32M
est: -123.96M (+15.0%)
-104.99M
est: -116.19M (+9.6%)
-89.75M
-101.69M – -77.82M
+22.8% YoY
-82.63M
-91.07M – -74.20M
+7.9% YoY
-125.33M
-184.89M – -65.76M
-51.7% YoY
18.38M
18.38M – 18.38M
+114.7% YoY
319.83M
319.83M – 319.83M
+1,640.6% YoY
SGA
15.20M
est: 38.00M (-60.0%)
33.25M
est: 38.19M (-12.9%)
42.79M
est: 45.94M (-6.9%)
42.08M
est: 37.14M (+13.3%)
42.12M
est: 45.24M (-6.9%)
36.20M
est: 38.37M (-5.7%)
27.33M
27.33M – 27.33M
-28.8% YoY
24.17M
24.17M – 24.17M
-11.6% YoY
21.85M
21.85M – 21.85M
-9.6% YoY
759.65M
759.65M – 759.65M
+3,377.0% YoY
2.49B
2.49B – 2.49B
+227.5% YoY
EPS
-1.54
est: -7.94 (+80.6%)
-1.82
est: -2.05 (+11.2%)
-2.62
est: -2.59 (-1.1%)
-2.67
est: -1.82 (-47.1%)
-1.52
est: -1.49 (-2.0%)
-1.27
est: -1.41 (+9.7%)
-1.09
-1.23 – -0.94
+22.6% YoY
-1.00
-1.10 – -0.90
+8.0% YoY
-1.31
-2.23 – -0.79
-30.4% YoY
0.22
0.22 – 0.22
+117.0% YoY
3.86
3.86 – 3.86
+1,640.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-08 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-07 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-06 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-05 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-04 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-05-01 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-30 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-29 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-27 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-24 C 2/5 1/5 1/5 1/5 2/5 1/5 5/5
2026-04-23 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-22 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-21 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-20 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-17 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-16 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-98.77M
OE per share TTM
-1.35
Owner's Yield
-37.59%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
146.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
27
Total invested
43.06M
Insider transactions (90d)
0
Beneficial owners (>5%)
40
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 STATE STREET CORPORATION 7.15M 10.43% 7.15M 7.15M HC BOSTON, MASSACHUSETTS 2024-04-10
2 SSGA FUNDS MANAGEMENT, INC. 6.98M 10.18% 6.98M 6.98M IA BOSTON, MASSACHUSETTS 2024-04-10
3 ArrowMark Colorado Holdings, LLC 5.80M 11.85% 5.80M 5.80M IA Delaware, United States 2023-02-14
4 Betta Investment (Hong Kong) Limited 5.57M 8.10% 5.57M 5.57M OO Hong Kong 2024-01-12
5 Betta Pharmaceuticals Co., Ltd. 5.57M 8.10% 5.57M 5.57M OO Hong Kong 2024-01-12
6 (1) BlackRock, Inc. 4.89M 7.10% 4.79M 4.79M HC Delaware 2024-11-08
7 Peter Kolchinsky 4.88M 9.90% 4.88M 4.88M HC, IN Delaware 2023-12-26
8 RA Capital Healthcare Fund, L.P. 4.88M 9.90% 4.88M 4.88M PN Delaware 2023-12-26
9 RA Capital Management, L.P. 4.88M 9.90% 4.88M 4.88M IA, PN Delaware 2023-12-26
10 Rajeev Shah 4.88M 9.90% 4.88M 4.88M HC, IN Delaware 2023-12-26
11 Alain Cohen 4.21M 9.80% 1.72M 2.48M 1.72M 11.00 IN 2020-10-16
12 52-0556948 4.08M 8.40% 820.4K 4.08M IA Maryland 2022-02-14
13 Capital LP 3.80M 7.70% 3.80M 3.80M IA Cayman Islands 2023-12-22
14 Capital Master LP 3.80M 7.70% 3.80M 3.80M OO Cayman Islands 2023-12-22
15 Lynx1 Capital Management LP 3.12M 6.30% 3.12M PN United States of America 2023-11-13
16 Weston Nichols 3.12M 6.30% 3.12M IN United States of America 2023-11-13
17 OrbiMed Capital LLC 2.93M 4.20% 2.93M 2.93M IA Delaware 2024-11-14
18 Steven A. Cohen 2.68M 5.40% 2.68M IN Delaware 2024-01-04
19 Guy Levy 2.56M 5.20% 2.56M 2.56M IN United States 2024-02-05
20 Soleus Capital Group, LLC 2.56M 5.20% 2.56M 2.56M OO United States 2024-02-05
21 Soleus Capital Master Fund, L.P. 2.56M 5.20% 2.56M 2.56M FI United States 2024-02-05
22 Soleus Capital, LLC 2.56M 5.20% 2.56M 2.56M OO United States 2024-02-05
23 RTW Investments, LP 2.49M 5.10% 2.49M IA, PN Delaware 2022-02-14
24 Roderick Wong 2.49M 5.10% 2.49M HC, IN United States 2022-02-14
25 Bihua Chen 2.49M 5.79% 2.49M 2.49M IN United States 2021-02-16
26 Cormorant Asset Management, LP 2.49M 5.79% 2.49M 2.49M PN Delaware 2021-02-16
27 Israel A. Englander 2.37M 4.80% 2.37M 2.37M IN Delaware 2023-07-25
28 Millennium Group Management LLC 2.37M 4.80% 2.37M 2.37M OO Delaware 2023-07-25
29 Millennium Management LLC 2.37M 4.80% 2.37M 2.37M OO Delaware 2023-07-25
30 Point72 Asset Management, L.P. 2.31M 4.70% 2.31M PN Delaware 2024-01-04
31 Point72 Capital Advisors, Inc. 2.31M 4.70% 2.31M CO Delaware 2024-01-04
32 Advisors LLC 2.21M 4.50% 2.21M 2.21M IA Delaware 2022-02-14
33 Edelman 2.21M 4.50% 2.21M IN Delaware 2022-02-14
34 Sciences Master Fund, Ltd. 2.21M 4.50% 2.21M CO Delaware 2022-02-14
35 Cormorant Private Healthcare Fund I, LP 1.87M 4.34% 1.87M 1.87M PN Delaware 2021-02-16
36 Cormorant Private Healthcare GP, LLC 1.87M 4.34% 1.87M 1.87M OO Delaware 2021-02-16
37 OrbiMed Advisors LLC 1.45M 2.10% 1.45M IA Delaware 2024-11-14
38 Cormorant Global Healthcare GP, LLC 522.0K 1.21% 522.0K 522.0K OO Delaware 2021-02-16
39 Cormorant Global Healthcare Master Fund, LP 522.0K 1.21% 522.0K 522.0K PN Cayman Islands 2021-02-16
40 Cubist Systematic Strategies, LLC 364.6K 0.70% 364.6K OO Delaware 2024-01-04

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
27
-81 vs prev Q
New positions
5
Closed positions
80
Increased
12
Reduced
7
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 POINT72 ASSET MANAGEMENT, L.P. 9.44M +9.4M (+100.0%) 18.03M +18.0M (+100.0%) 13.01% +13.008 pp 0.02% +0.020 pp USD1.91 +0.0% 1 qtrs NEW
2 MORGAN STANLEY 8.98M +4.0M (+80.6%) 17.15M +6.1M (+55.4%) 12.38% +5.375 pp 0.00% +0.000 pp USD3.60 -46.9% 21 qtrs
3 RA CAPITAL MANAGEMENT, L.P. 8.00M +8.0M (+100.0%) 15.28M +15.3M (+100.0%) 11.02% +11.025 pp 0.16% +0.157 pp USD1.91 +0.0% 1 qtrs NEW
4 BAIN CAPITAL LIFE SCIENCES INVESTORS, LLC 7.17M +6.1M (+545.0%) 13.70M +11.2M (+454.9%) 9.88% +8.318 pp 1.05% +0.885 pp USD6.75 -71.7% 21 qtrs
5 LYNX1 CAPITAL MANAGEMENT LP 7.10M +— (+0.0%) 13.56M -2.2M (-14.0%) 9.78% -0.215 pp 2.74% -0.463 pp USD4.78 -60.0% 10 qtrs
6 VANGUARD GROUP INC 4.38M +1.2M (+37.2%) 8.37M +1.3M (+18.1%) 6.04% +1.541 pp 0.00% +0.000 pp USD15.95 -88.0% 21 qtrs
7 WASATCH ADVISORS LP 4.34M -507.8K (-10.5%) 8.30M -2.5M (-23.0%) 5.99% -0.847 pp 0.05% -0.009 pp USD8.12 -76.5% 20 qtrs
8 SOLEUS CAPITAL MANAGEMENT, L.P. 3.80M -3.3M (-46.1%) 7.27M -8.4M (-53.6%) 5.24% -4.692 pp 0.27% -0.520 pp USD6.34 -69.9% 21 qtrs
9 BANK OF AMERICA CORP /DE/ 2.39M +334.4K (+16.3%) 4.56M +2.3K (+0.0%) 3.29% +0.399 pp 0.00% +0.000 pp USD4.74 -59.7% 21 qtrs
10 SILVERARC CAPITAL MANAGEMENT, LLC 1.99M +96.8K (+5.1%) 3.81M -403.2K (-9.6%) 2.75% +0.076 pp 0.53% -0.039 pp USD2.20 -13.2% 8 qtrs
11 BLACKROCK, INC. 1.97M +374.2K (+23.4%) 3.76M +220.0K (+6.2%) 2.71% +0.467 pp 0.00% +0.000 pp USD4.78 -60.0% 6 qtrs
12 SUSQUEHANNA INTERNATIONAL GROUP, LLP 1.78M +1.3M (+244.5%) 3.39M +2.2M (+196.4%) 2.45% +1.721 pp 0.00% +0.000 pp USD2.04 -6.4% 20 qtrs
13 RENAISSANCE TECHNOLOGIES LLC 1.60M +665.6K (+71.0%) 3.06M +980.9K (+47.2%) 2.21% +0.889 pp 0.00% +0.002 pp USD1.65 +15.8% 4 qtrs
14 TWO SIGMA INVESTMENTS, LP 1.51M +674.9K (+80.9%) 2.88M +1.0M (+55.6%) 2.08% +0.905 pp 0.00% +0.001 pp USD3.88 -50.8% 19 qtrs
15 ORBIMED ADVISORS LLC 1.40M -3.8M (-73.2%) 2.68M -8.9M (-76.9%) 1.94% -5.437 pp 0.06% -0.219 pp USD4.04 -52.7% 7 qtrs
16 MILLENNIUM MANAGEMENT LLC 1.19M -745.3K (-38.5%) 2.27M -2.0M (-47.1%) 1.64% -1.086 pp 0.00% -0.001 pp USD1.84 +3.8% 12 qtrs
17 GOLDMAN SACHS GROUP INC 1.09M +629.1K (+136.8%) 2.08M +1.1M (+103.7%) 1.50% +0.853 pp 0.00% +0.000 pp USD3.54 -46.0% 21 qtrs
18 TWO SIGMA ADVISERS, LP 1.07M +305.1K (+40.0%) 2.04M +346.2K (+20.4%) 1.47% +0.397 pp 0.00% +0.001 pp USD6.04 -68.4% 16 qtrs
19 GEODE CAPITAL MANAGEMENT, LLC 988.9K +263.6K (+36.3%) 1.89M +278.5K (+17.3%) 1.36% +0.341 pp 0.00% +0.000 pp USD10.12 -81.1% 21 qtrs
20 JANE STREET GROUP, LLC 874.8K +671.2K (+329.7%) 1.67M +1.2M (+269.7%) 1.21% +0.919 pp 0.00% +0.000 pp USD1.82 +4.9% 12 qtrs
21 WELLS FARGO & COMPANY/MN 809.3K +790.6K (+4,236.9%) 1.55M +1.5M (+3,631.3%) 1.12% +1.089 pp 0.00% +0.000 pp USD1.92 -0.5% 21 qtrs
22 ACADIAN ASSET MANAGEMENT LLC 657.2K +529.1K (+413.0%) 1.25M +969.0K (+343.6%) 0.91% +0.725 pp 0.00% +0.002 pp USD1.82 +4.9% 4 qtrs
23 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 449.4K +98.8K (+28.2%) 858.4K +80.1K (+10.3%) 0.62% +0.126 pp 0.00% +0.000 pp USD13.50 -85.9% 21 qtrs
24 CITADEL ADVISORS LLC 447.8K -33.6K (-7.0%) 855.3K -213.5K (-20.0%) 0.62% -0.061 pp 0.00% +0.000 pp USD2.22 -14.0% 2 qtrs
25 WALLEYE CAPITAL LLC 443.3K +443.3K (+100.0%) 846.8K +846.8K (+100.0%) 0.61% +0.611 pp 0.00% +0.003 pp USD1.91 +0.0% 1 qtrs NEW
26 683 CAPITAL MANAGEMENT, LLC 400.0K +400.0K (+100.0%) 764.0K +764.0K (+100.0%) 0.55% +0.551 pp 0.03% +0.033 pp USD1.91 +0.0% 1 qtrs NEW
27 STATE STREET CORP 342.8K +55.4K (+19.3%) 654.7K +16.7K (+2.6%) 0.47% +0.068 pp 0.00% +0.000 pp USD7.23 -73.6% 21 qtrs
28 DIMENSIONAL FUND ADVISORS LP 296.5K -52.8K (-15.1%) 566.5K -209.0K (-27.0%) 0.41% -0.083 pp 0.00% +0.000 pp USD7.73 -75.3% 14 qtrs
29 QUBE RESEARCH & TECHNOLOGIES LTD 290.2K +174.3K (+150.3%) 554.3K +296.9K (+115.3%) 0.40% +0.237 pp 0.00% +0.000 pp USD2.03 -5.9% 2 qtrs
30 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 272.1K +— (+0.0%) 519.6K -84.3K (-14.0%) 0.37% -0.008 pp 0.01% -0.002 pp USD1.85 +3.2% 3 qtrs
31 INVESCO LTD. 268.4K +76.5K (+39.9%) 512.5K +86.7K (+20.4%) 0.37% +0.100 pp 0.00% +0.000 pp USD2.74 -30.3% 21 qtrs
32 MARSHALL WACE, LLP 265.0K +158.8K (+149.4%) 506.2K +270.3K (+114.6%) 0.37% +0.216 pp 0.00% +0.000 pp USD2.03 -5.9% 2 qtrs
33 FMR LLC 254.4K +43.1K (+20.4%) 485.9K +16.7K (+3.6%) 0.35% +0.053 pp 0.00% +0.000 pp USD4.51 -57.6% 21 qtrs
34 LPL FINANCIAL LLC 243.3K +42.4K (+21.1%) 464.7K +18.6K (+4.2%) 0.34% +0.052 pp 0.00% +0.000 pp USD2.70 -29.3% 7 qtrs
35 HENNION & WALSH ASSET MANAGEMENT, INC. 237.1K +32.1K (+15.7%) 452.9K -2.2K (-0.5%) 0.33% +0.038 pp 0.02% -0.001 pp USD4.45 -57.1% 7 qtrs
36 BARCLAYS PLC 219.2K -24.3K (-10.0%) 418.7K -969.0K (-69.8%) 0.30% -0.041 pp 0.00% 0.000 pp USD2.86 -33.2% 16 qtrs
37 ARROWMARK COLORADO HOLDINGS LLC 204.5K +— (+0.0%) 390.6K -63.4K (-14.0%) 0.28% -0.006 pp 0.01% +0.000 pp USD3.61 -47.1% 21 qtrs
38 NORTHERN TRUST CORP 166.2K +27.9K (+20.2%) 317.5K +10.4K (+3.4%) 0.23% +0.034 pp 0.00% +0.000 pp USD9.15 -79.1% 21 qtrs
39 MAN GROUP PLC 156.1K +65.8K (+72.9%) 298.1K +97.7K (+48.8%) 0.22% +0.088 pp 0.00% +0.000 pp USD1.78 +7.3% 4 qtrs
40 SQUAREPOINT OPS LLC 136.1K +126.0K (+1,247.2%) 259.9K +237.4K (+1,059.1%) 0.19% +0.173 pp 0.00% +0.000 pp USD1.87 +2.1% 3 qtrs
41 QUADRATURE CAPITAL LTD 133.1K +133.1K (+100.0%) 254.2K +254.2K (+100.0%) 0.18% +0.183 pp 0.00% +0.003 pp USD1.91 +0.0% 4 qtrs
42 BRIDGEWAY CAPITAL MANAGEMENT, LLC 131.1K +51.2K (+64.1%) 250.4K +73.0K (+41.2%) 0.18% +0.068 pp 0.01% +0.002 pp USD1.72 +11.0% 4 qtrs
43 MARINER, LLC 128.1K -187.0 (-0.1%) 244.8K -39.9K (-14.0%) 0.18% -0.004 pp 0.00% 0.000 pp USD16.22 -88.2% 16 qtrs
44 OMERS ADMINISTRATION CORP 117.7K +117.7K (+100.0%) 224.8K +224.8K (+100.0%) 0.16% +0.162 pp 0.00% +0.002 pp USD1.91 +0.0% 1 qtrs NEW
45 HUDSON BAY CAPITAL MANAGEMENT LP 111.6K +111.6K (+100.0%) 213.1K +213.1K (+100.0%) 0.15% +0.154 pp 0.00% +0.001 pp USD1.91 +0.0% 3 qtrs
46 ATOM INVESTORS LP 105.0K +105.0K (+100.0%) 200.5K +200.5K (+100.0%) 0.14% +0.145 pp 0.02% +0.016 pp USD1.91 +0.0% 8 qtrs
47 XTX TOPCO LTD 104.5K -45.5K (-30.3%) 199.5K -133.4K (-40.1%) 0.14% -0.067 pp 0.01% -0.012 pp USD1.70 +12.4% 6 qtrs
48 GRAHAM CAPITAL MANAGEMENT, L.P. 102.2K +61.6K (+151.5%) 195.2K +105.0K (+116.4%) 0.14% +0.084 pp 0.00% +0.003 pp USD2.03 -5.9% 2 qtrs
49 VIENNA POWSZECHNE TOWARZYSTWO EMERYTALNE S.A. VIENNA INSURANCE GROUP 85.0K +— (+0.0%) 162.4K -26.4K (-14.0%) 0.12% -0.003 pp 0.08% -0.032 pp USD28.46 -93.3% 17 qtrs
50 AMERICAN CENTURY COMPANIES INC 68.2K +44.0K (+181.4%) 130.3K +76.5K (+142.1%) 0.09% +0.060 pp 0.00% +0.000 pp USD2.02 -5.4% 13 qtrs
51 SUSQUEHANNA FUNDAMENTAL INVESTMENTS, LLC 67.6K +— (+0.0%) 129.1K -21.0K (-14.0%) 0.09% -0.002 pp 0.00% -0.002 pp USD2.63 -27.4% 5 qtrs
52 CRESTWOOD ADVISORS GROUP LLC 66.5K +— (+0.0%) 127.1K -20.6K (-14.0%) 0.09% -0.002 pp 0.00% 0.000 pp USD1.88 +1.6% 3 qtrs
53 EXODUSPOINT CAPITAL MANAGEMENT, LP 62.2K +62.2K (+100.0%) 118.7K +118.7K (+100.0%) 0.09% +0.086 pp 0.00% +0.001 pp USD1.91 +0.0% 1 qtrs NEW
54 INTREPID FAMILY OFFICE LLC 55.0K -15.0K (-21.4%) 105.1K -50.4K (-32.4%) 0.08% -0.023 pp 0.09% -0.040 pp USD3.01 -36.5% 5 qtrs
55 D. E. SHAW & CO., INC. 52.9K +41.0K (+345.7%) 101.0K +74.7K (+283.5%) 0.07% +0.056 pp 0.00% +0.000 pp USD2.67 -28.5% 21 qtrs
56 UBS GROUP AG 52.8K -8.9K (-14.4%) 100.8K -36.1K (-26.4%) 0.07% -0.014 pp 0.00% +0.000 pp USD6.73 -71.6% 21 qtrs
57 CITIGROUP INC 49.8K +46.6K (+1,427.0%) 95.2K +87.9K (+1,213.7%) 0.07% +0.064 pp 0.00% +0.000 pp USD2.19 -12.8% 21 qtrs
58 CATALYST FUNDS MANAGEMENT PTY LTD 42.5K +— (+0.0%) 81.2K -13.2K (-14.0%) 0.06% -0.001 pp 0.02% +0.005 pp USD1.69 +13.0% 3 qtrs
59 GROUP ONE TRADING, L.P. 39.0K +26.6K (+213.7%) 74.5K +46.9K (+169.9%) 0.05% +0.036 pp 0.00% +0.000 pp USD2.01 -5.0% 7 qtrs
60 COLONY GROUP, LLC 38.2K +38.2K (+100.0%) 72.9K +72.9K (+100.0%) 0.05% +0.053 pp 0.00% +0.000 pp USD1.91 +0.0% 1 qtrs NEW
61 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 37.7K +37.7K (+100.0%) 72.0K +72.0K (+100.0%) 0.05% +0.052 pp 0.00% +0.000 pp USD1.91 +0.0% 1 qtrs NEW
62 JEFFERIES FINANCIAL GROUP INC. 35.3K -2.9K (-7.5%) 67.5K -17.3K (-20.4%) 0.05% -0.005 pp 0.00% 0.000 pp USD2.22 -14.0% 2 qtrs
63 LIGHTHOUSE INVESTMENT PARTNERS, LLC 33.7K +33.7K (+100.0%) 64.3K +64.3K (+100.0%) 0.05% +0.046 pp 0.00% +0.002 pp USD1.91 +0.0% 1 qtrs NEW
64 CALLAN FAMILY OFFICE, LLC 31.7K +31.7K (+100.0%) 60.6K +60.6K (+100.0%) 0.04% +0.044 pp 0.00% +0.001 pp USD1.91 +0.0% 1 qtrs NEW
65 SIMPLEX TRADING, LLC 30.7K +22.8K (+291.2%) 58.6K +41.6K (+244.4%) 0.04% +0.031 pp 0.00% +0.000 pp USD1.99 -4.0% 2 qtrs
66 CANADA PENSION PLAN INVESTMENT BOARD 29.5K +29.5K (+100.0%) 56.3K +56.3K (+100.0%) 0.04% +0.041 pp 0.00% +0.000 pp USD1.91 +0.0% 1 qtrs NEW
67 FARALLON CAPITAL MANAGEMENT LLC 28.0K +— (+0.0%) 53.5K -8.7K (-14.0%) 0.04% -0.001 pp 0.00% +0.000 pp USD8.10 -76.4% 8 qtrs
68 TOWER RESEARCH CAPITAL LLC (TRC) 26.0K +17.6K (+208.8%) 49.6K +30.9K (+165.7%) 0.04% +0.024 pp 0.00% +0.001 pp USD1.95 -2.1% 21 qtrs
69 CRESSET ASSET MANAGEMENT, LLC 25.0K +— (+0.0%) 47.8K -7.8K (-14.0%) 0.03% -0.001 pp 0.00% +0.000 pp USD4.73 -59.6% 17 qtrs
70 ENGINEERS GATE MANAGER LP 24.4K +8.1K (+49.9%) 46.6K +10.5K (+29.0%) 0.03% +0.011 pp 0.00% +0.000 pp USD1.78 +7.3% 8 qtrs
71 CI PRIVATE WEALTH, LLC 21.4K -1.3K (-5.8%) 40.9K -9.5K (-18.9%) 0.03% -0.003 pp 0.00% +0.000 pp USD2.02 -5.4% 13 qtrs
72 VIRTU FINANCIAL LLC 20.7K +20.7K (+100.0%) 39.0K +39.0K (+100.0%) 0.03% +0.029 pp 0.00% +0.002 pp USD1.91 +0.0% 3 qtrs
73 DELTA INVESTMENT MANAGEMENT, LLC 20.0K +20.0K (+100.0%) 38.2K +38.2K (+100.0%) 0.03% +0.028 pp 0.01% +0.007 pp USD1.91 +0.0% 1 qtrs NEW
74 EWA, LLC 16.9K -2.6K (-13.4%) 32.3K -11.1K (-25.5%) 0.02% -0.004 pp 0.01% -0.004 pp USD1.55 +23.2% 3 qtrs
75 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 15.8K +3.3K (+26.6%) 30.2K +2.5K (+8.9%) 0.02% +0.004 pp 0.00% +0.000 pp USD3.24 -41.0% 5 qtrs
76 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC 15.2K +650.0 (+4.5%) 29.1K -3.3K (-10.1%) 0.02% +0.001 pp 0.00% +0.000 pp USD1.61 +18.6% 4 qtrs
77 PRUDENTIAL FINANCIAL INC 15.1K +750.0 (+5.2%) 28.7K -3.0K (-9.5%) 0.02% +0.001 pp 0.00% +0.000 pp USD2.20 -13.2% 2 qtrs
78 HSBC HOLDINGS PLC 13.6K +— (+0.0%) 26.2K -3.9K (-12.9%) 0.02% 0.000 pp 0.00% +0.000 pp USD4.71 -59.4% 6 qtrs
79 R SQUARED LTD 13.7K -4.2K (-23.5%) 26.1K -13.6K (-34.2%) 0.02% -0.006 pp 0.01% -0.005 pp USD1.43 +33.6% 5 qtrs
80 JAIN GLOBAL LLC 12.8K +12.8K (+100.0%) 24.4K +24.4K (+100.0%) 0.02% +0.018 pp 0.00% +0.000 pp USD1.91 +0.0% 4 qtrs
81 PRICE T ROWE ASSOCIATES INC /MD/ 12.4K +— (+0.0%) 24.0K -4.0K (-14.3%) 0.02% 0.000 pp 0.00% +0.000 pp USD9.76 -80.4% 21 qtrs
82 NINE MASTS CAPITAL LTD 11.5K +11.5K (+100.0%) 21.9K +21.9K (+100.0%) 0.02% +0.016 pp 0.00% +0.004 pp USD1.91 +0.0% 1 qtrs NEW
83 ETHIC INC. 10.3K -230.0 (-2.2%) 19.6K -3.7K (-15.8%) 0.01% -0.001 pp 0.00% 0.000 pp USD1.43 +33.6% 3 qtrs
84 SIMPLICITY WEALTH,LLC 10.2K -11.0 (-0.1%) 19.5K -3.2K (-14.1%) 0.01% 0.000 pp 0.00% 0.000 pp USD2.22 -14.0% 2 qtrs
85 ABEL HALL, LLC 10.1K +— (+0.0%) 19.4K -3.1K (-14.0%) 0.01% 0.000 pp 0.00% -0.005 pp USD1.43 +33.6% 3 qtrs
86 BRONTE CAPITAL MANAGEMENT PTY LTD. 10.0K +10.0K (+100.0%) 19.2K +19.2K (+100.0%) 0.01% +0.014 pp 0.00% +0.002 pp USD1.91 +0.0% 1 qtrs NEW
87 BLACKSTON FINANCIAL ADVISORY GROUP, LLC 10.0K +10.0K (+100.0%) 19.1K +19.1K (+100.0%) 0.01% +0.014 pp 0.01% +0.012 pp USD1.91 +0.0% 1 qtrs NEW
88 JPMORGAN CHASE & CO 5.9K +1.5K (+34.2%) 11.4K +1.5K (+15.5%) 0.01% +0.002 pp 0.00% +0.000 pp USD3.84 -50.3% 21 qtrs
89 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. 4.7K +2.0K (+71.2%) 9.0K +2.9K (+47.3%) 0.01% +0.003 pp 0.00% +0.000 pp USD2.72 -29.8% 5 qtrs
90 ADVISOR GROUP HOLDINGS, INC. 4.5K +14.0 (+0.3%) 8.7K -2.6K (-23.1%) 0.01% 0.000 pp 0.00% +0.000 pp USD1.96 -2.6% 3 qtrs
91 NBC SECURITIES, INC. 4.0K +4.0K (+100.0%) 7.6K +7.6K (+100.0%) 0.01% +0.006 pp 0.00% +0.001 pp USD1.91 +0.0% 1 qtrs NEW
92 RHUMBLINE ADVISERS 2.7K +— (+0.0%) 5.2K -842.0 (-14.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD5.20 -63.3% 21 qtrs
93 BNP PARIBAS ARBITRAGE, SNC 2.2K -78.6K (-97.3%) 4.1K -175.3K (-97.7%) 0.00% -0.111 pp 0.00% 0.000 pp USD1.51 +26.5% 5 qtrs
94 GF FUND MANAGEMENT CO. LTD. 1.9K +440.0 (+30.1%) 3.6K +387.0 (+11.9%) 0.00% +0.001 pp 0.00% +0.000 pp USD2.97 -35.7% 5 qtrs
95 CAITONG INTERNATIONAL ASSET MANAGEMENT CO., LTD 1.2K -17.9K (-93.6%) 2.3K -40.2K (-94.5%) 0.00% -0.025 pp 0.00% -0.029 pp USD2.22 -14.0% 2 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 55 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Invesco NASDAQ Future Gen 200 ETF QQQS 0.46% 101.9K 0.20%
2 ALPS Medical Breakthroughs ETF SBIO 0.23% 490.2K 0.50%
3 iShares Micro-Cap ETF IWC 0.09% 1.38M 0.60%
4 Fidelity Enhanced Small Cap ETF FESM 0.06% 3.18M 0.28%
5 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.03% 350.1K 0.35%
6 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.03% 23.4K 0.35%
7 iShares Biotechnology ETF IBB 0.03% 2.93M 0.44%
8 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.03% 142.9K 0.40%
9 Invesco Nasdaq Biotechnology ETF IBBQ 0.03% 23.1K 0.19%
10 Invesco RAFI US 1500 Small-Mid ETF PRFZ 0.03% 839.4K 0.34%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
2
Sells
0
Shares acquired
9.6K
Shares disposed
Cash buys
Cash sales
Net activity
+9,629
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-01 GROGAN DONNA ROY Director A-Award A Common Stock 5,370 2.70 14.5K 71,512 D
2026-04-01 Anderson Kenneth Carl Director A-Award A Common Stock 4,259 2.70 11.5K 68,230 D
2026-02-15 Hirsch Andrew Director / Officer F-InKind D Common Stock 9,057 1.89 17.1K 1,074,934 D
2026-02-14 Schick Kelly Officer F-InKind D Common Stock 7,269 1.89 13.7K 299,881 D
2026-02-14 REYNO LEONARD Officer F-InKind D Common Stock 16,579 1.89 31.3K 379,803 D
2026-02-14 Mossler Mark Officer M-Exempt A Common Stock 9,420 0.00 75,184 D
2026-02-14 Mahaney Paige Officer F-InKind D Common Stock 2,446 1.89 4.6K 336,910 D
2026-02-14 Hirsch Andrew Director / Officer F-InKind D Common Stock 39,154 1.89 74.0K 1,083,991 D
2026-02-14 Boyle Scott N Officer F-InKind D Common Stock 7,269 1.89 13.7K 298,801 D
2026-02-14 Adams Kendra Officer M-Exempt A Common Stock 30,950 0.00 400,479 D
2026-02-13 Schick Kelly Officer F-InKind D Common Stock 1,735 1.89 3.3K 307,150 D
2026-02-13 REYNO LEONARD Officer A-Award A Common Stock 240,000 0.00 396,382 D
2026-02-13 Mossler Mark Officer A-Award A Common Stock 56,980 0.00 75,184 D
2026-02-13 Mahaney Paige Officer A-Award A Common Stock 240,000 0.00 339,356 D
2026-02-13 Hirsch Andrew Director / Officer A-Award A Common Stock 700,000 0.00 1,123,145 D
2026-02-13 Boyle Scott N Officer F-InKind D Common Stock 1,735 1.89 3.3K 306,070 D
2026-02-13 Adams Kendra Officer F-InKind D Common Stock 1,863 1.89 3.5K 400,479 D
2026-01-16 REYNO LEONARD Officer S-Sale D Common Stock 10,000 2.22 22.2K 156,382 D
2026-01-02 GROGAN DONNA ROY Director A-Award A Common Stock 7,513 1.93 14.5K 66,142 D
2026-01-02 Anderson Kenneth Carl Director A-Award A Common Stock 5,958 1.93 11.5K 146,532 D
2025-10-28 Mahaney Paige Officer F-InKind D Common Stock 5,644 2.58 14.6K 99,356 D
2025-10-01 GROGAN DONNA ROY Director A-Award A Common Stock 6,740 2.15 14.5K 58,629 D
2025-10-01 Anderson Kenneth Carl Director A-Award A Common Stock 5,349 2.15 11.5K 140,574 D
2025-09-18 Adams Kendra Officer M-Exempt A Common Stock 6,250 0.00 165,117 D
2025-07-10 REYNO LEONARD Officer M-Exempt A Common Stock 15,325 0.00 173,764 D
2025-07-01 GROGAN DONNA ROY Director A-Award A Common Stock 9,609 1.51 14.5K 51,889 D
2025-07-01 Anderson Kenneth Carl Director A-Award A Common Stock 7,616 1.51 11.5K 135,225 D
2025-06-18 Koppikar Utpal Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Hughes Owen Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Hoerter Steven L. Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 GROGAN DONNA ROY Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Fawell Stephen Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Cooper Ronald Harold Wilfred Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Bessen Laura Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-06-18 Anderson Kenneth Carl Director A-Award A Stock Option (Right to Buy) 35,500 1.44 51.1K 35,500 D
2025-04-01 GROGAN DONNA ROY Director A-Award A Common Stock 9,581 1.44 13.7K 42,280 D
2025-04-01 Anderson Kenneth Carl Director A-Award A Common Stock 7,841 1.44 11.3K 127,609 D
2025-02-18 Boyle Scott N Officer S-Sale D Common Stock 669 3.15 2.1K 107,805 D
2025-02-15 Hirsch Andrew Director / Officer F-InKind D Common Stock 9,370 3.18 29.8K 423,145 D
2025-02-14 Siegel Jolie Officer A-Award A Stock Option (Right to Buy) 84,700 3.18 269.3K 84,700 D
2025-02-14 Schick Kelly Officer A-Award A Stock Option (Right to Buy) 84,700 3.18 269.3K 84,700 D
2025-02-14 REYNO LEONARD Officer A-Award A Stock Option (Right to Buy) 130,600 3.18 415.3K 130,600 D
2025-02-14 Mossler Mark Officer F-InKind D Common Stock 1,586 3.18 5.0K 18,204 D
2025-02-14 Mahaney Paige Officer A-Award A Stock Option (Right to Buy) 42,400 3.18 134.8K 42,400 D
2025-02-14 Hirsch Andrew Director / Officer A-Award A Common Stock 223,500 0.00 445,362 D
2025-02-14 Boyle Scott N Officer A-Award A Stock Option (Right to Buy) 84,700 3.18 269.3K 84,700 D
2025-02-14 Adams Kendra Officer A-Award A Stock Option (Right to Buy) 130,600 3.18 415.3K 130,600 D
2025-02-13 Siegel Jolie Officer F-InKind D Common Stock 2,135 3.20 6.8K 54,353 D
2025-02-13 Schick Kelly Officer F-InKind D Common Stock 1,735 3.20 5.6K 54,753 D
2025-02-13 Boyle Scott N Officer F-InKind D Common Stock 1,735 3.20 5.6K 54,832 D
2025-02-13 Adams Kendra Officer F-InKind D Common Stock 1,863 3.20 6.0K 82,576 D
2025-01-02 GROGAN DONNA ROY Director A-Award A Common Stock 3,757 3.66 13.8K 32,699 D
2025-01-02 Anderson Kenneth Carl Director A-Award A Common Stock 3,074 3.66 11.3K 119,768 D
2024-11-19 Hoerter Steven L. Director 0 0.00 0
2024-11-07 Siegel Jolie Officer M-Exempt A Common Stock 3,750 0.00 57,590 D
2024-11-07 Schick Kelly Officer M-Exempt A Common Stock 3,750 0.00 57,590 D
2024-11-07 Hirsch Andrew Director / Officer M-Exempt A Common Stock 12,500 0.00 227,412 D
2024-11-07 Boyle Scott N Officer M-Exempt A Common Stock 3,750 0.00 57,669 D
2024-11-07 Adams Kendra Officer M-Exempt A Common Stock 3,750 0.00 85,541 D
2024-10-28 Mahaney Paige Officer 0 0.00 0
2024-10-01 GROGAN DONNA ROY Director A-Award A Common Stock 2,474 5.56 13.8K 28,942 D
2024-10-01 Anderson Kenneth Carl Director A-Award A Common Stock 2,023 5.56 11.2K 116,694 D
2024-09-18 Adams Kendra Officer F-InKind D Common Stock 1,837 6.38 11.7K 81,791 D
2024-09-16 Siegel Jolie Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 14,250
2024-09-16 Schick Kelly Officer M-Exempt A Common Stock 2,250 0.00 54,501
2024-09-16 Hirsch Andrew Director / Officer M-Exempt D Performance Restricted Stock Units 7,500 0.00 47,500
2024-09-16 Fisher Stewart Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 14,250
2024-09-16 Boyle Scott N Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 14,250
2024-09-16 Adams Kendra Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 14,250
2024-08-29 Fawell Stephen Director A-Award A Stock Option (Right to Buy) 65,000 6.43 418.0K 65,000
2024-07-10 REYNO LEONARD Officer F-InKind D Common Stock 6,191 5.00 31.0K 91,809
2024-07-01 GROGAN DONNA ROY Director A-Award A Common Stock 2,836 4.85 13.8K 26,468
2024-07-01 Anderson Kenneth Carl Director A-Award A Common Stock 2,320 4.85 11.3K 114,671
2024-06-20 Salter Malcolm Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 Koppikar Utpal Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 Hughes Owen Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 GROGAN DONNA ROY Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 DOWNEY BRUCE Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 Bessen Laura Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-20 Anderson Kenneth Carl Director A-Award A Stock Option (Right to Buy) 32,500 4.05 131.6K 32,500
2024-06-07 Cooper Ronald Harold Wilfred Director 0 0.00 0
2024-04-01 GROGAN DONNA ROY Director A-Award A Common Stock 1,697 8.10 13.7K 23,632
2024-04-01 Dubin Glenn Director A-Award A Common Stock 1,358 8.10 11.0K 22,075
2024-04-01 Anderson Kenneth Carl Director A-Award A Common Stock 1,389 8.10 11.3K 112,351
2024-03-07 Siegel Jolie Officer D-Return D Stock Option (Right to Buy) 84,850 45.54 3.86M 0
2024-03-07 Schick Kelly Officer D-Return D Stock Option (Right to Buy) 78,500 22.71 1.78M 0
2024-03-07 Fisher Stewart Officer D-Return D Stock Option (Right to Buy) 118,000 22.71 2.68M 0
2024-03-07 Boyle Scott N Officer D-Return D Stock Option (Right to Buy) 115,000 33.23 3.82M 0
2024-03-07 Adams Kendra Officer D-Return D Stock Option (Right to Buy) 45,000 22.71 1.02M 0
2024-02-15 Hirsch Andrew Director / Officer F-InKind D Common Stock 6,560 7.90 51.8K 210,741
2024-02-14 Siegel Jolie Officer A-Award A Common Stock 27,300 0.00 52,251
2024-02-14 Schick Kelly Officer A-Award A Stock Option (Right to Buy) 122,800 7.31 897.7K 122,800
2024-02-14 REYNO LEONARD Officer A-Award A Stock Option (Right to Buy) 165,300 7.31 1.21M 165,300
2024-02-14 Mossler Mark Officer A-Award A Stock Option (Right to Buy) 27,430 7.31 200.5K 27,430
2024-02-14 Hirsch Andrew Director / Officer A-Award A Stock Option (Right to Buy) 465,500 7.31 3.40M 465,500
2024-02-14 Fisher Stewart Officer A-Award A Stock Option (Right to Buy) 122,800 7.31 897.7K 122,800
2024-02-14 Boyle Scott N Officer A-Award A Common Stock 27,300 0.00 52,330
2024-02-14 Adams Kendra Officer A-Award A Stock Option (Right to Buy) 165,300 7.31 1.21M 165,300
2024-02-13 Siegel Jolie Officer F-InKind D Common Stock 1,735 6.53 11.3K 24,951
2024-02-13 Schick Kelly Officer F-InKind D Common Stock 1,735 6.53 11.3K 24,951
2024-02-13 Fisher Stewart Officer F-InKind D Common Stock 2,255 6.53 14.7K 101,821
2024-02-13 Boyle Scott N Officer F-InKind D Common Stock 1,735 6.53 11.3K 25,030
2024-02-13 Adams Kendra Officer F-InKind D Common Stock 1,301 6.53 8.5K 45,339
2024-01-02 GROGAN DONNA ROY Director A-Award A Common Stock 2,108 6.52 13.7K 21,935
2024-01-02 Dubin Glenn Director A-Award A Common Stock 1,687 6.52 11.0K 20,717
2024-01-02 Anderson Kenneth Carl Director A-Award A Common Stock 1,725 6.52 11.2K 110,962
2023-11-16 Hughes Owen Director A-Award A Stock Option (Right to Buy) 52,000 1.82 94.6K 52,000
2023-10-02 GROGAN DONNA ROY Director A-Award A Common Stock 8,089 1.70 13.8K 19,827
2023-10-02 Dubin Glenn Director A-Award A Common Stock 6,470 1.70 11.0K 19,030
2023-10-02 Anderson Kenneth Carl Director A-Award A Common Stock 6,617 1.70 11.2K 109,237
2023-09-18 Siegel Jolie Officer A-Award A Stock Option (Right to Buy) 120,000 2.15 258.0K 120,000
2023-09-18 Schick Kelly Officer A-Award A Stock Option (Right to Buy) 120,000 2.15 258.0K 120,000
2023-09-18 Mossler Mark Officer D Stock Option (Right to Buy) 50,210 2.83 142.1K 0
2023-09-18 Hirsch Andrew Director / Officer A-Award A Stock Option (Right to Buy) 489,600 2.15 1.05M 489,600
2023-09-18 Fisher Stewart Officer A-Award A Stock Option (Right to Buy) 120,000 2.15 258.0K 120,000
2023-09-18 Boyle Scott N Officer A-Award A Stock Option (Right to Buy) 120,000 2.15 258.0K 120,000
2023-09-18 Adams Kendra Officer A-Award A Stock Option (Right to Buy) 111,000 2.15 238.7K 111,000
2023-08-30 White Lauren Officer M-Exempt A Common Stock 2,250 0.00 33,347
2023-08-30 Siegel Jolie Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 16,500
2023-08-30 Schick Kelly Officer M-Exempt D Performance Restricted Stock Units 2,250 0.00 16,500
2023-08-30 Hirsch Andrew Director / Officer M-Exempt D Performance Restricted Stock Units 7,500 0.00 55,000
2023-08-30 Fisher Stewart Officer M-Exempt A Common Stock 2,250 0.00 104,737
2023-08-30 Boyle Scott N Officer M-Exempt A Common Stock 2,250 0.00 27,426
2023-07-10 REYNO LEONARD Officer A-Award A Common Stock 61,300 0.00 61,300
2023-07-03 GROGAN DONNA ROY Director A-Award A Common Stock 4,858 2.83 13.7K 11,738
2023-07-03 Dubin Glenn Director A-Award A Common Stock 3,887 2.83 11.0K 12,560
2023-07-03 Anderson Kenneth Carl Director A-Award A Common Stock 3,976 2.83 11.3K 102,620
2023-06-15 Salter Malcolm Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 Koppikar Utpal Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 GROGAN DONNA ROY Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 Dubin Glenn Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 DOWNEY BRUCE Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 Bessen Laura Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-06-15 Anderson Kenneth Carl Director A-Award A Stock Option (Right to Buy) 26,000 3.61 93.9K 26,000
2023-04-03 GROGAN DONNA ROY Director A-Award A Common Stock 4,298 3.20 13.8K 6,880
2023-04-03 Anderson Kenneth Carl Director A-Award A Common Stock 3,516 3.20 11.3K 98,644
2023-02-15 Hirsch Andrew Director / Officer A-Award A Stock Option (Right to Buy) 367,200 5.77 2.12M 367,200
2023-02-13 White Lauren Officer A-Award A Common Stock 26,000 0.00 31,097
2023-02-13 Siegel Jolie Officer A-Award A Common Stock 20,000 0.00 25,097
2023-02-13 Schick Kelly Officer A-Award A Common Stock 20,000 0.00 25,097
2023-02-13 Fisher Stewart Officer A-Award A Common Stock 26,000 0.00 102,487
2023-02-13 Boyle Scott N Officer A-Award A Common Stock 20,000 0.00 25,176
2023-02-08 Koppikar Utpal Director P-Purchase A Common Stock 5,667 5.60 31.7K 5,667
2023-01-30 White Lauren Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 18,750
2023-01-30 Siegel Jolie Officer F-InKind D Common Stock 1,301 7.78 10.1K 5,097
2023-01-30 Schick Kelly Officer F-InKind D Common Stock 1,301 7.78 10.1K 5,097
2023-01-30 Hirsch Andrew Director / Officer F-InKind D Common Stock 4,319 7.78 33.6K 27,006
2023-01-30 Fisher Stewart Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 18,750
2023-01-30 Crystal Adam Officer M-Exempt A Common Stock 3,750 0.00 21,398
2023-01-30 Boyle Scott N Officer F-InKind D Common Stock 1,222 7.78 9.5K 5,176
2023-01-06 Anderson Kenneth Carl Director M-Exempt A Common Stock 444 4.98 2.2K 95,128
2023-01-03 GROGAN DONNA ROY Director A-Award A Common Stock 1,763 6.38 11.2K 2,582
2023-01-03 Dubin Glenn Director A-Award A Common Stock 1,725 6.38 11.0K 5,235
2023-01-03 Anderson Kenneth Carl Director A-Award A Common Stock 1,568 6.38 10.0K 94,416
2022-10-03 GROGAN DONNA ROY Director A-Award A Common Stock 819 8.69 7.1K 819
2022-10-03 Dubin Glenn Director A-Award A Common Stock 1,265 8.69 11.0K 3,510
2022-10-03 Anderson Kenneth Carl Director A-Award A Common Stock 1,150 8.69 10.0K 92,848
2022-07-29 GROGAN DONNA ROY Director A-Award A Stock Option (Right to Buy) 41,200 0.00 41,200
2022-07-29 Bessen Laura Director A-Award A Stock Option (Right to Buy) 41,200 0.00 41,200
2022-07-15 Anderson Kenneth Carl Director M-Exempt D Stock Option (Right to Buy) 889 4.98 4.4K 1,779
2022-07-01 Dubin Glenn Director A-Award A Common Stock 1,372 8.03 11.0K 2,245
2022-07-01 Anderson Kenneth Carl Director A-Award A Common Stock 1,246 8.03 10.0K 89,562
2022-06-22 Salter Malcolm Director A-Award A Stock Option (Right to Buy) 23,500 0.00 23,500
2022-06-22 Dubin Glenn Director A-Award A Stock Option (Right to Buy) 23,500 0.00 23,500
2022-06-22 DOWNEY BRUCE Director A-Award A Stock Option (Right to Buy) 23,500 0.00 23,500
2022-06-22 COHEN MARC A Director A-Award A Stock Option (Right to Buy) 23,500 0.00 23,500
2022-06-22 Anderson Kenneth Carl Director A-Award A Stock Option (Right to Buy) 23,500 6.06 142.4K 23,500
2022-05-26 White Lauren Officer F-InKind D Common Stock 1,102 7.01 7.7K 2,648
2022-05-26 Siegel Jolie Officer F-InKind D Common Stock 1,102 7.01 7.7K 2,648
2022-05-26 Schick Kelly Officer F-InKind D Common Stock 1,102 7.01 7.7K 2,648
2022-05-26 Hirsch Andrew Director / Officer F-InKind D Common Stock 3,675 7.01 25.8K 18,825
2022-05-26 Fisher Stewart Officer F-InKind D Common Stock 1,102 7.01 7.7K 74,038
2022-05-26 Crystal Adam Officer F-InKind D Common Stock 1,102 7.01 7.7K 17,648
2022-05-26 Boyle Scott N Officer F-InKind D Common Stock 1,102 7.01 7.7K 2,648
2022-05-25 White Lauren Officer M-Exempt A Common Stock 3,750 0.00 3,750
2022-05-25 Siegel Jolie Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 22,500
2022-05-25 Schick Kelly Officer M-Exempt A Common Stock 3,750 0.00 3,750
2022-05-25 Hirsch Andrew Officer M-Exempt A Common Stock 12,500 0.00 22,500
2022-05-25 Fisher Stewart Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 22,500
2022-05-25 Crystal Adam Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 22,500
2022-05-25 Boyle Scott N Officer M-Exempt D Performance Restricted Stock Units 3,750 0.00 22,500
2022-04-12 Hirsch Andrew Officer P-Purchase A Common Stock 10,000 8.40 84.0K 10,000
2022-04-12 Fisher Stewart Officer M-Exempt A Common Stock 2,156 3.71 8.0K 45,462
2022-04-04 Dubin Glenn Director A-Award A Common Stock 379 26.46 10.0K 873
2022-04-04 COHEN ALAIN J Director A-Award A Common Stock 388 26.46 10.3K 928
2022-04-04 Anderson Kenneth Carl Director A-Award A Common Stock 341 26.46 9.0K 88,316
2022-03-16 Schick Kelly Officer D Stock Option (Right to Buy) 92,000 37.46 3.45M 0
2022-03-16 Koppikar Utpal Director 0 0.00 0
2022-03-16 Boyle Scott N Officer D Stock Option (Right to Buy) 115,000 33.23 3.82M 0
2022-02-23 Hirsch Andrew Director / Officer A-Award A Performance Restricted Stock Units 87,500 0.00 87,500
2022-02-14 White Lauren Officer A-Award A Stock Option (Right to Buy) 100,000 22.71 2.27M 100,000
2022-02-14 Siegel Jolie Officer A-Award A Stock Option (Right to Buy) 90,000 22.71 2.04M 90,000
2022-02-14 Fisher Stewart Officer A-Award A Stock Option (Right to Buy) 118,000 22.71 2.68M 118,000
2022-02-14 Crystal Adam Officer A-Award A Stock Option (Right to Buy) 118,000 22.71 2.68M 118,000
2022-01-26 Anderson Kenneth Carl Director M-Exempt D Stock Option (Right to Buy) 1,334 4.98 6.6K 2,668
2022-01-04 Salter Malcolm Director A-Award A Common Stock 428 31.58 13.5K 11,380
2022-01-04 Dubin Glenn Director A-Award A Common Stock 199 31.58 6.3K 494
2022-01-04 Crystal Adam Officer S-Sale D Common Stock 1,054 32.66 34.4K 15,000
2022-01-04 COHEN MARC A Director A-Award A Common Stock 657 31.58 20.7K 1,118
2022-01-04 COHEN ALAIN J Director A-Award A Common Stock 318 31.58 10.0K 540

Executive team

Top executives
EBIT / Employee
-9.5K
Shares Outstanding
82.83M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Andrew J. Hirsch President & Chief Executive Officer 694.9K 100.0K 710.7K 848.0K 573.3K 14.0K 2.94M 53.00%
2 2025 Leonard Reyno, M.D. Chief Medical Officer 597.7K 100.0K 277.0K 330.3K 322.8K 14.0K 1.64M 36.99%
3 2025 Kendra R. Adams Chief Financial Officer 506.8K 75.0K 277.0K 330.3K 273.7K 14.0K 1.48M 41.12%
4 2024 Andrew J. Hirsch President & Chief Executive Officer 665.0K 755.9K 2.80M 402.3K 13.8K 4.63M 76.66%
5 2024 Leonard Reyno, M.D. Chief Medical Officer 572.0K 268.3K 992.9K 251.7K 13.8K 2.10M 60.09%
6 2024 Kendra R. Adams Chief Financial Officer 485.0K 268.3K 1.00M 213.4K 12.8K 1.98M 64.12%
7 2023 Andrew J. Hirsch President & Chief Executive Officer 639.0K 470.8K 2.33M 333.9K 13.2K 3.79M 73.98%
8 2023 Leonard Reyno, M.D. Chief Medical Officer 262.7K 268.4K 214.6K 709.6K 209.0K 10.5K 1.67M 55.18%
9 2023 Stewart Fisher, Ph.D. Chief Scientific Officer 479.2K 147.4K 711.9K 182.0K 13.3K 1.53M 56.02%
10 2023 Kendra R. Adams Chief Financial Officer 404.6K 138.8K 489.0K 171.0K 7.3K 1.21M 51.86%
11 2022 Scott N. Boyle, Ph.D. Chief Business Officer 398.7K 100.0K 558.7K 2.68M 159.1K 14.9K 3.91M 82.81%
12 2022 Stewart Fisher, Ph.D. Chief Scientific Officer 460.8K 558.7K 1.89M 184.3K 12.2K 3.10M 78.83%
13 2022 Andrew J. Hirsch President & Chief Executive Officer 614.4K 1.62M 337.9K 18.7K 2.60M 62.59%
14 2021 Lauren A. White Chief Financial Officer 220.3K 60.0K 3.70M 102.8K 6.0K 4.09M 90.48%
15 2021 Stewart Fisher, Ph.D. Chief Scientific Officer 434.7K 54.0K 3.09M 200.0K 6.0K 3.79M 81.66%
16 2021 Adam S. Crystal, M.D., Ph.D. Chief Medical Officer 434.7K 61.0K 2.86M 200.0K 6.0K 3.56M 80.31%
17 2021 Jolie M. Siegel Chief Legal Officer & Secretary 414.0K 2.77M 190.4K 6.0K 3.38M 81.92%
18 2021 Andrew J. Hirsch President & Chief Executive Officer 579.6K 366.6K 6.0K 952.2K 0.00%
19 2021 William T. McKee Former Chief Financial Officer 348.4K 348.4K 0.00%
20 2020 Andrew J. Hirsch President & Chief Executive Officer 167.9K 20.66M 98.8K 5.6K 20.93M 98.70%
21 2020 Marc A. Cohen Interim Chief Executive Officer 9.06M 69.5K 9.13M 99.24%
22 2020 William T. McKee Former Chief Financial Officer 1.03M 1.07M 2.10M 48.83%
23 2020 William T. McKee Chief Financial Officer 1.03M 1.07M 2.10M 48.83%
24 2020 Adam S. Crystal, M.D., Ph.D. Chief Medical Officer 409.8K 61.0K 941.8K 184.8K 6.0K 1.60M 58.74%
25 2020 Stewart Fisher, Ph.D. Chief Scientific Officer 379.7K 54.0K 963.5K 186.5K 6.0K 1.59M 60.61%
26 2020 Andrew Phillips, Ph.D. Former President & Chief Executive Officer 94.5K 523.8K 618.3K 0.00%
27 2019 Andrew Phillips, Ph.D. Former President & Chief Executive Officer 520.0K 3.38M 260.0K 36.4K 4.19M 80.53%
28 2019 Adam S. Crystal, M.D., Ph.D. Chief Medical Officer 344.3K 100.0K 1.12M 120.5K 6.4K 1.69M 66.21%
29 2019 Stewart Fisher, Ph.D. Chief Scientific Officer 340.3K 119.1K 6.3K 465.8K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A
2025-04-16 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-04-29 DEFA14A
2026-04-29 DEF 14A
2026-04-29 ARS
2026-04-22 SC 13G/A
2026-04-10 8-K
2026-04-09 8-K
2026-04-03 4
2026-04-03 4
2026-02-26 S-8
2026-02-26 8-K

Executive team

NameTitleCompensationGender
Andrew J. Hirsch Chief Executive Officer, President & Director 1M male
Leonard J. Reyno Chief Medical Officer 1M
Kendra Adams Chief Financial Officer and Head of Corporate Affairs & Treasurer 869.5K female
Paige Mahaney Chief Scientific Officer 657.3K female
Kenneth C. Anderson Co-Founder, Independent Director & Member of Scientific Advisory Board 45.8K
Courtney Solberg Senior Manager of Investor Relations female
Isabel Chiu Senior Vice President of Strategic Alliances & Business Development
Mark Mossler Chief Accounting Officer male
Nathanael S. Gray Co-Founder & Member of Scientific Advisory Board
Christopher Nasveschuk Senior Vice President of Chemistry
Kelly Schick Chief People Officer female
ESG Rating
B
BIOTECHNOLOGY
Rank: 500 out of 710
2025
E (Environmental)
53.8 / 56.3
Company / Sector avg.
S (Social)
66.1 / 62.4
Company / Sector avg.
G (Governance)
60.7 / 60.9
Company / Sector avg.
ESG Total
60.2 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits