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Bolt Biotherapeutics, Inc. (BOLT)

USD4.12 +0.07 (+1.73%)
US NASDAQ Healthcare Biotechnology
Address 900 Chesapeake Drive 94063
Redwood City, CA, US
CEO William Quinn
IPO 2021-02-05
CIK 1641281 ISIN US0977022039

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Description

Bolt Biotherapeutics, Inc. is a biotechnology company currently conducting clinical trials, focused on developing innovative immuno-oncology therapies. Its mission is to create agents that equip the body's immune system to identify and eliminate cancerous cells. A key therapeutic in its pipeline is BDC-1001, an investigational treatment targeting the human epidermal growth factor receptor 2 (HER2). This compound is presently undergoing Phase I/II clinical evaluation for patients with HER2-positive solid tumors, including those exhibiting low HER2 expression. Beyond BDC-1001, the company is advancing several other programs: BDC-2034, which targets carcinoembryonic antigen for various indications such as colorectal, non-small cell lung, pancreatic, and breast cancers; and BDC-3042, a Dectin-2 agonist antibody designed to reprogram crucial immune cells within the tumor microenvironment by interacting with macrophage cell-surface receptors. Bolt is also pursuing a programmed cell death-ligand 1 (PD-L1) initiative aimed at addressing tumors that prove resistant to existing immune checkpoint blockades. Incorporated in 2015 under its previous name, Bolt Therapeutics, Inc., before officially becoming Bolt Biotherapeutics, Inc. in July of the same year, the company maintains its corporate headquarters in Redwood City, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD4.12 +0.07 (+1.73%)
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Volume Profile
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Liquidity & share structure
Average Volume
29.7K
Beta
1.17
Float Shares
1.55M
Free Float %
80.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+1.70% +2.58% +2.58% -3.43% +1.70% -12.61% -30.72% -87.74% -98.70% -99.26% -99.26%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (8 ratings, all time) Hold
Price Targets & DCF
Current price
4.12
Low 1.00 -75.7%
Consensus 4.00 -2.9%
Median 4.00 -2.9%
High 7.00 +69.9%
Ratings Trend (MoM) 50% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 2 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year 1
7.00
+69.9%
All Time 2
4.00
-2.9%
Quality scores
Altman Z-Score
-14.88
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +0.1% Q1'26: -97.9% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -981.8% Q1'26: -1,386.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -589.1% Q1'26: -30,857.7% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -450.1% Q1'26: +0.0% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -157.7% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    -95.1% Q1'26: -56.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.69× Q1'26: -0.73× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.10) × ERP
WACC = 28% × Ke + 72% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 4.12
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
2 Rev. Ana.
1 EPS Ana.
Dec 2027
2 Rev. Ana.
1 EPS Ana.
Dec 2028
2 Rev. Ana.
2 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Revenue
231.0K
est: 265.5K (-13.0%)
1.26M
est: 1.96M (-35.7%)
5.73M
est: 5.68M (+0.9%)
7.88M
est: 11.17M (-29.5%)
7.69M
est: 8.47M (-9.2%)
7.70M
est: 5.87M (+31.2%)
3.00M
857.1K – 5.14M
-48.8% YoY
7.00M
2.00M – 12.00M
+133.3% YoY
8.00M
2.29M – 13.71M
+14.3% YoY
8.00M
2.29M – 13.71M
+0.0% YoY
8.00M
2.29M – 13.71M
+0.0% YoY
EBITDA
-48.57M
est: -265.5K (-18,194.2%)
-91.60M
est: -1.96M (-4,571.3%)
-88.66M
est: -5.68M (-1,461.2%)
-74.34M
est: -11.17M (-565.8%)
-66.46M
est: -8.47M (-684.4%)
-33.14M
est: -5.87M (-465.1%)
-3.00M
-5.14M – -857.1K
+48.8% YoY
-7.00M
-12.00M – -2.00M
-133.3% YoY
-8.00M
-13.71M – -2.29M
-14.3% YoY
-8.00M
-13.71M – -2.29M
+0.0% YoY
-8.00M
-13.71M – -2.29M
+0.0% YoY
EBIT
-49.18M
est: -265.5K (-18,424.3%)
-92.79M
est: -1.96M (-4,632.2%)
-90.32M
est: -5.68M (-1,490.6%)
-76.20M
est: -11.17M (-582.4%)
-68.24M
est: -8.47M (-705.4%)
-34.63M
est: -5.87M (-490.5%)
-3.00M
-5.14M – -857.1K
+48.8% YoY
-7.00M
-12.00M – -2.00M
-133.3% YoY
-8.00M
-13.71M – -2.29M
-14.3% YoY
-8.00M
-13.71M – -2.29M
+0.0% YoY
-8.00M
-13.71M – -2.29M
+0.0% YoY
Net Income
-60.73M
est: -2.90B (+97.9%)
-98.59M
est: -2.39B (+95.9%)
-88.10M
est: -1.78B (+95.0%)
-69.20M
est: -3.26M (-2,025.4%)
-63.12M
est: -60.15M (-4.9%)
-33.38M
est: -39.69M (+15.9%)
-37.36M
-79.05M – -2.93M
+5.9% YoY
-23.75M
-89.22M – -3.30M
+36.4% YoY
-30.00M
-111.22M – -4.12M
-26.3% YoY
-66.44M
-128.13M – -4.75M
-121.5% YoY
-74.97M
-144.58M – -5.35M
-12.8% YoY
SGA
9.06M
est: 3.35M (+170.4%)
18.39M
est: 24.73M (-25.6%)
22.93M
est: 71.62M (-68.0%)
22.53M
est: 57.29M (-60.7%)
18.46M
est: 43.47M (-57.5%)
13.80M
est: 30.09M (-54.2%)
15.39M
4.40M – 26.39M
-48.8% YoY
35.91M
10.26M – 61.57M
+133.3% YoY
41.04M
11.73M – 70.36M
+14.3% YoY
41.04M
11.73M – 70.36M
+0.0% YoY
41.04M
11.73M – 70.36M
+0.0% YoY
EPS
-1.99
est: -76.07 (+97.4%)
-2.79
est: -62.56 (+95.5%)
-2.30
est: -47.17 (+95.1%)
-1.83
est: -1.74 (-5.1%)
-1.65
est: -32.27 (+94.9%)
-17.85
est: -21.23 (+15.9%)
-21.92
-42.27 – -1.57
-3.3% YoY
-24.74
-47.71 – -1.77
-12.9% YoY
-30.84
-59.48 – -2.20
-24.7% YoY
-35.53
-68.52 – -2.54
-15.2% YoY
-40.09
-77.32 – -2.86
-12.8% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-11 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-08 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-07 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-06 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-05 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-04 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-01 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-30 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-29 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-27 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-24 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-23 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-22 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-21 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-20 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-17 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-16 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-26.22M
OE per share TTM
-7.16
Owner's Yield
-32.64%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
510.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
21
Total invested
3.30M
Insider transactions (90d)
0
Beneficial owners (>5%)
26
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Novo Holdings A/S 4.50M 13.00% 4.50M 4.50M CO 2021-02-11
2 Dr. James I. Healy (“Healy”) 2.75M 8.00% 2.75M 2.75M IN      U.S. Citizen 2021-02-16
3 Dr. Maha Katabi (“Katabi”) 2.75M 8.00% 2.75M 2.75M IN      Canadian Citizen 2021-02-16
4 Dr. Michael F. Powell (“Powell”) 2.75M 8.00% 2.75M 2.75M IN      U.S. Citizen 2021-02-16
5 Sofinnova Management X, L.L.C. (“SM X”) 2.75M 8.00% 2.75M 2.75M 10.00 OO      Delaware 2021-02-16
6 Sofinnova Venture Partners X, L.P. (“SVP X”) 2.75M 8.00% 2.75M 2.75M PN      Delaware 2021-02-16
7 Peter Kolchinsky 2.38M 6.50% 2.38M 2.38M HC, IN Delaware 2021-04-07
8 RA Capital Management, L.P. 2.38M 6.50% 2.38M 2.38M IA, PN Delaware 2021-04-07
9 Rajeev Shah 2.38M 6.50% 2.38M 2.38M HC, IN Delaware 2021-04-07
10 Vivo Capital VIII, LLC 2.27M 6.60% 2.27M 2.27M OO Delaware 2021-02-18
11 Aaron Cowen 2.23M 6.00% 2.23M 2.23M HC, IN Delaware 2021-11-29
12 Averill Master Fund, Ltd. 2.23M 6.00% 2.23M 2.23M CO Delaware 2021-11-29
13 Suvretta Capital Management, LLC 2.23M 6.00% 2.23M 2.23M IA, OO Delaware 2021-11-29
14 RA Capital Healthcare Fund, L.P. 1.92M 5.30% 1.92M 1.92M PN Delaware 2021-04-07
15 Pivotal bioVenture Partners Fund I G.P., L.P. 1.89M 5.50% 1.89M 1.89M PN 2021-02-17
16 Pivotal bioVenture Partners Fund I U.G.P., Ltd. 1.89M 5.50% 1.89M 1.89M CO 2021-02-17
17 Pivotal bioVenture Partners Fund I, L.P. 1.89M 5.50% 1.89M 1.89M PN 2021-02-17
18 Vivo Panda, LLC 1.45M 4.20% 1.45M 1.45M OO Delaware 2021-02-18
19 Vivo Opportunity, LLC 150.0K 0.40% 150.0K 150.0K OO Delaware 2021-02-18
20 CALC IV LP 10.00 12.00% 412.00 HC, PN Delaware 2021-02-19
21 Citadel Securities GP LLC 10.00 12.00% 412.00 HC, OO Delaware 2021-02-19
22 Citadel Securities LLC 10.00 12.00% 412.00 BD, OO Delaware 2021-02-19
23 Citadel Advisors Holdings LP 10.00 8.10% 2.94M HC, PN Delaware 2021-02-19
24 Citadel Advisors LLC 10.00 8.10% 2.94M IA, HC, OO Delaware 2021-02-19
25 Citadel GP LLC 10.00 8.10% 2.94M HC, OO Delaware 2021-02-19
26 Kenneth Griffin 10.00 8.10% 2.94M HC, IN Delaware 2021-02-19

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2025 Q4
Investors holding
21
-3 vs prev Q
New positions
3
Closed positions
6
Increased
7
Reduced
4
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 NANO CAP NEW MILLENNIUM GROWTH FUND L P 20.5K +20.5K (+100.0%) 112.09M +112.1M (+100.0%) 1.07% +1.068 pp 0.10% +0.096 pp USD5.47 +0.0% 1 qtrs NEW
2 SOFINNOVA INVESTMENTS, INC. 137.7K +— (+0.0%) 753.1K +20.4K (+2.8%) 7.18% -0.007 pp 0.03% -0.008 pp USD5.77 -5.2% 3 qtrs
3 PIVOTAL BIOVENTURE PARTNERS INVESTMENT ADVISOR LLC 94.6K +— (+0.0%) 517.1K +14.0K (+2.8%) 4.93% -0.005 pp 0.20% -0.091 pp USD5.77 -5.2% 3 qtrs
4 VIVO CAPITAL, LLC 72.4K -103.7K (-58.9%) 396.0K -540.7K (-57.7%) 3.77% -5.409 pp 0.03% -0.050 pp USD5.77 -5.2% 3 qtrs
5 NAN FUNG GROUP HOLDINGS LTD 58.3K +— (+0.0%) 319.0K +8.6K (+2.8%) 3.04% -0.003 pp 0.29% -0.235 pp USD5.77 -5.2% 3 qtrs
6 RENAISSANCE TECHNOLOGIES LLC 55.0K +26.4K (+92.2%) 300.9K +148.6K (+97.6%) 2.87% +1.374 pp 0.00% +0.000 pp USD5.54 -1.3% 3 qtrs
7 38.0K +38.0K (+100.0%) 207.8K +207.8K (+100.0%) 1.98% +1.980 pp 0.26% +0.258 pp USD5.47 +0.0% 1 qtrs NEW
8 BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 36.0K -1.0 (0.0%) 196.7K +5.3K (+2.8%) 1.87% -0.002 pp 0.04% +0.017 pp USD5.77 -5.2% 3 qtrs
9 PFIZER INC 31.3K +— (+0.0%) 171.2K +4.6K (+2.8%) 1.63% -0.002 pp 0.07% +0.034 pp USD5.77 -5.2% 3 qtrs
10 GEODE CAPITAL MANAGEMENT, LLC 18.8K +270.0 (+1.5%) 103.1K +4.4K (+4.5%) 0.98% +0.013 pp 0.00% +0.000 pp USD5.77 -5.2% 3 qtrs
11 SHAY CAPITAL LLC 15.3K -686.0 (-4.3%) 83.5K -1.4K (-1.6%) 0.80% -0.037 pp 0.01% +0.001 pp USD5.32 +2.8% 2 qtrs
12 VANGUARD GROUP INC 10.2K -24.1K (-70.3%) 55.8K -126.3K (-69.4%) 0.53% -1.255 pp 0.00% +0.000 pp USD5.77 -5.2% 3 qtrs
13 BLACKROCK, INC. 9.7K +— (+0.0%) 53.1K +1.4K (+2.8%) 0.51% -0.001 pp 0.00% +0.000 pp USD5.77 -5.2% 3 qtrs
14 MORGAN STANLEY 3.1K +— (+0.0%) 17.1K +463.0 (+2.8%) 0.16% 0.000 pp 0.00% +0.000 pp USD5.77 -5.2% 3 qtrs
15 TOWER RESEARCH CAPITAL LLC (TRC) 723.00 +464.0 (+179.2%) 4.0K +2.6K (+186.9%) 0.04% +0.024 pp 0.00% +0.000 pp USD5.58 -2.0% 3 qtrs
16 UBS GROUP AG 515.00 +512.0 (+17,066.7%) 2.8K +2.8K (+17,500.0%) 0.03% +0.027 pp 0.00% +0.000 pp USD5.47 +0.0% 3 qtrs
17 CITIGROUP INC 256.00 +256.0 (+100.0%) 1.4K +1.4K (+100.0%) 0.01% +0.013 pp 0.00% +0.000 pp USD5.47 +0.0% 1 qtrs NEW
18 JPMORGAN CHASE & CO 42.00 +— (+0.0%) 230.00 +7.0 (+3.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.76 -5.0% 3 qtrs
19 BANK OF AMERICA CORP /DE/ 31.00 +— (+0.0%) 169.00 +4.0 (+2.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.74 -4.7% 3 qtrs
20 SBI SECURITIES CO., LTD. 10.00 +— (+0.0%) 55.00 +2.0 (+3.8%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.70 -4.0% 3 qtrs
21 BARCLAYS PLC 6.00 +— (+0.0%) 33.00 +1.0 (+3.1%) 0.00% +0.000 pp 0.00% +0.000 pp USD5.67 -3.5% 3 qtrs
22 TANG CAPITAL MANAGEMENT LLC -66.9K (-100.0%) -355.8K (-100.0%) 0.00% -3.488 pp 0.00% -0.014 pp USD 3 qtrs SOLD
23 SAMSARA BIOCAPITAL, LLC -48.8K (-100.0%) -259.8K (-100.0%) 0.00% -2.546 pp 0.00% -0.034 pp USD 3 qtrs SOLD
24 SUSQUEHANNA INTERNATIONAL GROUP, LLP -16.6K (-100.0%) -88.5K (-100.0%) 0.00% -0.868 pp 0.00% +0.000 pp USD 2 qtrs SOLD
25 DRW SECURITIES, LLC -12.3K (-100.0%) -65.6K (-100.0%) 0.00% -0.643 pp 0.00% -0.001 pp USD 2 qtrs SOLD
26 SQUAREPOINT OPS LLC -14.8K (-100.0%) -78.9K (-100.0%) 0.00% -0.774 pp 0.00% 0.000 pp USD 3 qtrs SOLD
27 SALEM INVESTMENT COUNSELORS INC -2.0 (-100.0%) -11.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 3 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 1 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Vanguard Extended Market ETF VXF 0.00% 36.2K 0.05%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
3
Sells
0
Shares acquired
93.0K
Shares disposed
Cash buys
Cash sales
Net activity
+93,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-01-28 Yonehiro Grant Officer A-Award A Employee Stock Option (Right to Buy) 10,000 6.71 67.1K 10,000 D
2026-01-28 Quinn William P. Director / Officer A-Award A Employee Stock Option (Right to Buy) 20,000 6.71 134.2K 20,000 D
2026-01-28 Nemec Sarah Officer A-Award A Employee Stock Option (Right to Buy) 8,000 6.71 53.7K 8,000 D
2025-12-12 Yonehiro Grant Officer A-Award A Employee Stock Option (Right to Buy) 822 5.44 4.5K 822 D
2025-12-12 Quinn William P. Director / Officer D-Return D Employee Stock Option (Right to Buy) 11,749 25.40 298.4K 0 D
2025-12-12 ONETTO NICOLE Director A-Award A Director Stock Option (Right to Buy) 1,100 5.44 6.0K 1,100 D
2025-12-12 O'CALLAGHAN BRIAN Director D-Return D Director Stock Option (Right to Buy) 1,100 15.36 16.9K 0 D
2025-12-12 Nemec Sarah Officer D-Return D Employee Stock Option (Right to Buy) 2,199 61.60 135.5K 0 D
2025-12-12 LAPORTE KATHLEEN Director D-Return D Director Stock Option (Right to Buy) 1,250 32.60 40.8K 0 D
2025-12-12 Dupont Jakob Director D-Return D Director Stock Option (Right to Buy) 849 13.60 11.5K 0 D
2025-12-12 Berner Laura Director A-Award A Director Stock Option (Right to Buy) 1,100 5.44 6.0K 1,100 D
2025-12-05 Quinn William P. Director / Officer P-Purchase A Common Stock 125 4.61 575.88 2,313 D
2025-12-05 Nemec Sarah Officer P-Purchase A Common Stock 125 4.61 575.88 1,415 D
2025-10-22 Yonehiro Grant Officer A-Award A Common Stock 30,000 0.00 38,918 D
2025-10-22 Quinn William P. Director / Officer A-Award A Common Stock 40,000 0.00 42,188 D
2025-10-22 Nemec Sarah Officer A-Award A Common Stock 23,000 0.00 23,943 D
2025-06-06 Quinn William P. Director / Officer P-Purchase A Common Stock 125 5.49 686.50 2,188 D
2025-06-06 Nemec Sarah Officer P-Purchase A Common Stock 125 5.49 686.50 943 D
2025-05-27 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 1,100 6.40 7.0K 1,100 D
2025-05-27 O'CALLAGHAN BRIAN Director A-Award A Stock Option (Right to Buy) 1,100 6.40 7.0K 1,100 D
2025-05-27 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 1,100 6.40 7.0K 1,100 D
2025-05-27 Dupont Jakob Director A-Award A Stock Option (Right to Buy) 1,100 6.40 7.0K 1,100 D
2025-05-27 Berner Laura Director A-Award A Stock Option (Right to Buy) 1,100 6.40 7.0K 1,100 D
2025-05-01 Yonehiro Grant Officer A-Award A Stock Option (Right to Buy) 350,000 0.35 122.9K 350,000 D
2025-05-01 Quinn William P. Director / Officer A-Award A Stock Option (Right to Buy) 700,000 0.35 245.7K 700,000 D
2025-05-01 Nemec Sarah Officer A-Award A Stock Option (Right to Buy) 226,000 0.35 79.3K 226,000 D
2025-05-01 Dupont Jakob Director A-Award A Stock Option (Right to Buy) 20,000 0.35 7.0K 20,000 D
2024-12-16 Quinn William P. Director / Officer P-Purchase A Common Stock 2,500 0.50 1.2K 41,272 D
2024-12-16 Nemec Sarah Officer P-Purchase A Common Stock 2,500 0.50 1.2K 16,633 D
2024-09-03 Dupont Jakob Director A-Award A Stock Option (Right to Buy) 50,000 0.68 34.0K 50,000
2024-07-23 Yonehiro Grant Officer A-Award A Stock Option (Right to Buy) 155,000 0.73 113.2K 155,000
2024-07-23 Quinn William P. Director / Officer A-Award A Stock Option (Right to Buy) 440,000 0.73 321.2K 440,000
2024-07-23 Nemec Sarah Officer A-Award A Stock Option (Right to Buy) 90,000 0.73 65.7K 90,000
2024-06-12 SHAH MAHENDRA Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 O'CALLAGHAN BRIAN Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 Lee Frank D. Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 HEALY JAMES Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-12 Berner Laura Director A-Award A Stock Option (Right to Buy) 22,000 0.77 16.9K 22,000
2024-06-06 Quinn William P. Director / Officer P-Purchase A Common Stock 2,500 0.64 1.6K 38,772 D
2024-06-06 Nemec Sarah Officer P-Purchase A Common Stock 2,500 0.64 1.6K 13,863 D
2024-05-15 Nemec Sarah Officer D Stock Option (Right to Buy) 7,500 20.00 150.0K 0
2024-03-04 Yonehiro Grant Officer A-Award A Stock Option (Right to Buy) 235,000 1.27 298.5K 235,000
2024-03-04 Schatzman Randall C Director / Officer A-Award A Stock Option (Right to Buy) 654,000 1.27 830.6K 235,000
2024-03-04 Quinn William P. Officer A-Award A Stock Option (Right to Buy) 235,000 1.27 298.5K 235,000
2024-03-04 Perez Edith A. Officer A-Award A Stock Option (Right to Buy) 235,000 1.27 298.5K 235,000
2023-12-31 Yonehiro Grant Officer 0 0.00 0
2023-12-31 Schatzman Randall C Director / Officer 0 0.00 0
2023-12-31 Perez Edith A. Officer 0 0.00 0
2023-12-12 Quinn William P. Officer P-Purchase A Common Stock 7,500 0.95 7.1K 36,272
2023-12-06 Quinn William P. Officer P-Purchase A Common Stock 2,500 0.78 2.0K 28,772
2023-11-30 ENGLEMAN EDGAR Director S-Sale D Common Stock 108,145 0.86 92.8K 1,821,483
2023-11-29 ENGLEMAN EDGAR Director S-Sale D Common Stock 22,674 0.91 20.5K 1,929,628
2023-11-21 Vivo Capital VIII, LLC 10% Owner S-Sale D Common Stock 1,707 0.90 1.5K 1,952,302
2023-11-21 ENGLEMAN EDGAR Director S-Sale D Common Stock 1,707 0.90 1.5K 1,952,302
2023-11-20 Vivo Capital VIII, LLC 10% Owner S-Sale D Common Stock 23,443 0.92 21.6K 113,119
2023-11-20 ENGLEMAN EDGAR Director S-Sale D Common Stock 27,465 0.92 25.3K 1,954,009
2023-11-17 Vivo Capital VIII, LLC 10% Owner S-Sale D Common Stock 7,009 0.93 6.5K 136,562
2023-11-17 ENGLEMAN EDGAR Director S-Sale D Common Stock 8,211 0.93 7.6K 1,981,474
2023-11-16 Vivo Capital VIII, LLC 10% Owner S-Sale D Common Stock 7,531 0.96 7.2K 1,989,685
2023-11-16 ENGLEMAN EDGAR Director S-Sale D Common Stock 7,531 0.96 7.2K 1,989,685
2023-06-12 SHAH MAHENDRA Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 O'CALLAGHAN BRIAN Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 MILLER RICHARD A MD Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 Lee Frank D. Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 HEALY JAMES Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 ENGLEMAN EDGAR Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-12 Berner Laura Director A-Award A Stock Option (Right to Buy) 25,000 1.63 40.8K 25,000
2023-06-06 Quinn William P. Officer P-Purchase A Common Stock 1,829 1.18 2.2K 26,272
2023-02-27 Yonehiro Grant Officer A-Award A Stock Option (Right to Buy) 228,000 1.59 362.5K 228,000
2023-02-27 Schatzman Randall C Director / Officer A-Award A Stock Option (Right to Buy) 728,270 1.59 1.16M 728,270
2023-02-27 Quinn William P. Officer A-Award A Stock Option (Right to Buy) 250,000 1.59 397.5K 250,000
2023-02-27 Perez Edith A. Officer A-Award A Stock Option (Right to Buy) 250,000 1.59 397.5K 250,000
2022-12-31 Yonehiro Grant Officer 0 0.00 0
2022-12-31 Schatzman Randall C Director / Officer 0 0.00 0
2022-12-31 Quinn William P. Officer 0 0.00 0
2022-12-31 Perez Edith A. Officer 0 0.00 0
2022-12-14 MILLER RICHARD A MD Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-12-14 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-12-14 Berner Laura Director A-Award A Stock Option (Right to Buy) 50,000 0.00 50,000
2022-07-13 Novo Holdings A/S Director S-Sale D COMMON STOCK 800,000 2.00 1.60M 3,703,991
2022-06-10 SHAH MAHENDRA Director A-Award A Stock Option (Right to Buy) 25,000 1.99 49.8K 25,000
2022-06-10 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-06-10 O'CALLAGHAN BRIAN Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-06-10 MILLER RICHARD A MD Director A-Award A Stock Option (Right to Buy) 25,000 1.99 49.8K 25,000
2022-06-10 Lee Frank D. Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-06-10 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-06-10 HEALY JAMES Director A-Award A Stock Option (Right to Buy) 25,000 1.99 49.8K 25,000
2022-06-10 ENGLEMAN EDGAR Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-03-24 SHAH MAHENDRA Director A-Award A Stock Option (Right to Buy) 25,000 3.03 75.8K 25,000
2022-03-24 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 12,227 3.03 37.0K 12,227
2022-03-24 O'CALLAGHAN BRIAN Director A-Award A Stock Option (Right to Buy) 14,071 0.00 14,071
2022-03-24 MILLER RICHARD A MD Director A-Award A Stock Option (Right to Buy) 25,000 3.03 75.8K 25,000
2022-03-24 Lee Frank D. Director A-Award A Stock Option (Right to Buy) 14,071 0.00 14,071
2022-03-24 LAPORTE KATHLEEN Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-03-24 HEALY JAMES Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-03-24 ENGLEMAN EDGAR Director A-Award A Stock Option (Right to Buy) 25,000 0.00 25,000
2022-02-18 Yonehiro Grant Officer A-Award A Stock Option (Right to Buy) 190,000 3.08 585.2K 190,000
2022-02-18 Schatzman Randall C Director / Officer A-Award A Stock Option (Right to Buy) 630,000 3.08 1.94M 630,000
2022-02-18 Quinn William P. Officer A-Award A Stock Option (Right to Buy) 210,000 3.08 646.8K 210,000
2022-02-18 Perez Edith A. Officer A-Award A Stock Option (Right to Buy) 210,000 3.08 646.8K 210,000
2022-02-18 Dornan David Officer A-Award A Stock Option (Right to Buy) 210,000 3.08 646.8K 210,000
2021-12-22 Perez Edith A. Officer M-Exempt D Stock Option (Right to Buy) 35,714 2.80 100.0K 189,286
2021-12-14 ONETTO NICOLE Director A-Award A Stock Option (Right to Buy) 27,860 4.19 116.7K 27,860
2021-12-08 Quinn William P. Officer P-Purchase A Common Stock 5,000 4.72 23.6K 20,154
2021-12-06 Quinn William P. Officer P-Purchase A Common Stock 35 4.64 162.40 15,154
2021-12-06 Perez Edith A. Officer P-Purchase A Common Stock 411 4.64 1.9K 1,328
2021-11-17 O'CALLAGHAN BRIAN Director D No securities are beneficially owned. 0 0.00 0
2021-11-17 Lee Frank D. Director D No securities are beneficially owned. 0 0.00 0
2021-06-04 Quinn William P. Officer P-Purchase A Common Stock 1,221 16.65 20.3K 15,119
2021-06-04 Perez Edith A. Officer P-Purchase A Common Stock 917 16.65 15.3K 917
2021-02-09 Vivo Capital VIII, LLC 10% Owner P-Purchase A Common Stock 150,000 20.00 3.00M 150,000
2021-02-09 Sofinnova Venture Partners X, L.P. 10% Owner P-Purchase A Common Stock 450,000 20.00 9.00M 2,754,437
2021-02-09 Schatzman Randall C Director / Officer P-Purchase A Common Stock 1,500 20.00 30.0K 1,500
2021-02-09 SHAH MAHENDRA Director S-Sale D Common Stock 62 20.00 1.2K 1,448,286
2021-02-09 Quinn William P. Officer P-Purchase A Common Stock 1,200 20.00 24.0K 13,898
2021-02-09 Novo Holdings A/S 10% Owner P-Purchase A COMMON STOCK 400,000 20.00 8.00M 4,503,991
2021-02-09 LAPORTE KATHLEEN Director P-Purchase A Common Stock 1,200 20.00 24.0K 1,200
2021-02-09 Khanna Ashish Siri Ram Director P-Purchase A Common Stock 1,200 20.00 24.0K 1,200
2021-02-09 HEALY JAMES Director C-Conversion D Series C-2 Preferred Stock 1,200,228 0.00 0
2021-02-09 ENGLEMAN EDGAR Director / 10% Owner P-Purchase A Common Stock 175,733 20.00 3.51M 1,997,216
2021-02-04 Yonehiro Grant Officer D Stock Option (Right to Buy) 16,444 2.03 33.4K 0
2021-02-04 Vivo Capital VIII, LLC 10% Owner I Common Stock 0 0.00 25,104
2021-02-04 Sofinnova Venture Partners X, L.P. 10% Owner D Series C-1 Preferred Stock 1,104,209 0.00 0
2021-02-04 Schatzman Randall C Director / Officer D Stock Option (Right to Buy) 791,185 2.73 2.16M 0
2021-02-04 SHAH MAHENDRA Director I Common Stock 0 0.00 14,285
2021-02-04 Quinn William P. Officer D Common Stock 0 0.00 12,698
2021-02-04 Perez Edith A. Officer A-Award A Stock Option (Right to Buy) 100,000 20.00 2.00M 100,000
2021-02-04 Novo Holdings A/S 10% Owner D SERIES A-1 PREFERRED STOCK 1,096,323 0.00 0
2021-02-04 Moldt Peter Director 0 0.00 0
2021-02-04 MILLER RICHARD A MD Director D Stock Option (Right to Buy) 10,808 2.73 29.5K 0
2021-02-04 LAPORTE KATHLEEN Director D Stock Option (Right to Buy) 27,857 4.41 122.8K 0
2021-02-04 Khanna Ashish Siri Ram Director I Stock Option (Right to Buy) 10,000 4.34 43.4K 0
2021-02-04 HEALY JAMES Director I Series C-1 Preferred Stock 1,104,209 0.00 0
2021-02-04 ENGLEMAN EDGAR Director / 10% Owner I Series C-1 Preferred Stock 43,901 0.00 0
2021-02-04 Dornan David Officer D Stock Option (Right to Buy) 26,460 2.24 59.3K 0

Executive team

Top executives
EBIT / Employee
-6.7K
Shares Outstanding
1.92M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 William P. Quinn President, Chief Executive Officer and Chief Financial Officer 463.5K 191.2K 224.4K 3.67M 10.5K 4.56M 85.41%
2 2025 Grant Yonehiro Chief Operating Officer 463.5K 139.1K 168.3K 3.24M 4.01M 84.96%
3 2024 Randall C. Schatzman, Ph.D. Former Chief Executive Officer 405.4K 653.0K 380.5K 1.44M 45.38%
4 2024 William P. Quinn President, Chief Executive Officer and Chief Financial Officer 453.6K 247.5K 491.9K 10.4K 1.20M 40.88%
5 2024 William P. Quinn President, Chief Executive Officer and Chief Financial Officer 453.6K 247.5K 491.9K 10.4K 1.20M 40.88%
6 2024 Grant Yonehiro Chief Operating Officer 443.1K 180.0K 325.3K 948.4K 34.30%
7 2024 Grant Yonehiro Chief Operating Officer 443.1K 180.0K 325.3K 948.4K 34.30%
8 2024 Edith Perez, M.D. Former Chief Medical Officer 327.7K 234.6K 319.8K 882.1K 26.60%
9 2023 Randall C. Schatzman, Ph.D. Former Chief Executive Officer 599.1K 263.7K 877.9K 9.9K 1.75M 50.15%
10 2023 Edith Perez, M.D. Former Chief Medical Officer 486.6K 170.4K 301.4K 24.3K 982.7K 30.67%
11 2023 William P. Quinn President, Chief Executive Officer and Chief Financial Officer 441.8K 159.1K 301.4K 9.9K 912.2K 33.04%
12 2023 Grant Yonehiro Chief Operating Officer 415.1K 149.6K 274.9K 839.5K 32.74%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-25 DEF 14A
2025-04-16 PRE 14A
2025-04-15 DEF 14A
2024-05-20 DEFA14A
2024-04-26 DEFA14A
2024-04-26 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-12 8-K
2026-05-12 10-Q
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS
2026-03-12 S-8
2026-03-12 8-K
2026-03-12 10-K
2026-02-26 SC 13D/A
2026-02-17 SC 13D/A

Executive team

NameTitleCompensationGender
William Quinn Chief Executive Officer, Chief Financial Officer, President, Secretary & Director 665.2K male
Grant Yonehiro Chief Operating Officer & Chief Business Officer 602.6K male
Justin Kenkel Senior Principal Scientist male
Michael N. Alonso Senior Vice President of Research
Sarah Nemec Senior Vice President of Finance & Principal Accounting Officer female
ESG Rating
B
BIOTECHNOLOGY
Rank: 403 out of 662
2026
E (Environmental)
54.8 / 56.3
Company / Sector avg.
S (Social)
64.9 / 62.4
Company / Sector avg.
G (Governance)
62.2 / 60.9
Company / Sector avg.
ESG Total
60.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend yield history

Dividend history

Earnings history

Earnings reports

Stock splits