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Boundless Bio, Inc. (BOLD)

USD2.49 +0.03 (+1.02%)
US NASDAQ Healthcare Biotechnology
Address 9880 Campus Point Drive 92121
San Diego, CA, US
CEO Zachary Hornby
IPO 2016-07-20
CIK 1782303 ISIN US10170A1007

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Description

Boundless Bio, Inc., a clinical-stage oncology company, focuses on developing innovative cancer therapies aimed at addressing the significant unmet needs of patients with oncogene amplified tumors. Their core strategy involves targeting extrachromosomal DNA (ecDNA). The company's lead product candidate, BBI-355, an orally administered inhibitor of checkpoint kinase 1 (CHK1), is currently in Phase 1/2 clinical trials for patients suffering from oncogene amplified cancers. Additionally, Boundless Bio is advancing BBI-825, another oral inhibitor, this one targeting ribonucleotide reductase (RNR), also in Phase 1/2 clinical development for cancer patients exhibiting resistance gene amplifications. A third initiative, the ecDTx 3 program, is designed to target a kinesin crucial for the cellular segregation mechanism of ecDNA. Incorporated in 2018, the company originally operated as Pretzel Therapeutics, Inc. before adopting the name Boundless Bio, Inc. in July 2019. Its headquarters are situated in San Diego, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD2.49 +0.03 (+1.02%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.97
Float Shares
17.17M
Free Float %
76.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-3.23% -5.66% +32.74% +32.74% +21.95% +25.00% +0.67% -89.47% -89.47% -89.47% -89.47%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (20 ratings, all time) Hold
Price Targets & DCF
Current price
2.49
Ratings Trend (MoM) 0% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 0 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-2.98
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +32.5% Q1'26: +15.5% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    -158.5% Q1'26: -138.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +31.7% Q1'26: +0.5% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.79× Q1'26: -0.85× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.95) × ERP
WACC = 40% × Ke + 60% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 2.49
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
1 EPS Ana.
Dec 2027
2 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
1 EPS Ana.
Dec 2030
1 EPS Ana.
Revenue
— – —
— – —
8.40M
8.40M – 8.40M
— – —
-100.0% YoY
— – —
EBITDA
-64.28M
-62.30M
— – —
— – —
— – —
— – —
— – —
EBIT
-65.36M
-63.55M
— – —
— – —
— – —
— – —
— – —
Net Income
-65.36M
est: -65.69M (+0.5%)
-58.20M
est: -55.23M (-5.4%)
-53.22M
-53.22M – -53.22M
+3.6% YoY
-28.62M
-28.62M – -28.62M
+46.2% YoY
-24.48M
-24.48M – -24.48M
+14.5% YoY
-29.96M
-29.96M – -29.96M
-22.4% YoY
-31.30M
-31.30M – -31.30M
-4.5% YoY
SGA
18.00M
18.71M
— – —
— – —
— – —
— – —
— – —
EPS
-3.85
est: -3.83 (-0.5%)
-2.60
est: -2.47 (-5.3%)
-2.38
-2.38 – -2.38
+3.6% YoY
-1.28
-1.28 – -1.28
+46.2% YoY
-1.10
-1.10 – -1.10
+14.5% YoY
-1.34
-1.34 – -1.34
-22.4% YoY
-1.40
-1.40 – -1.40
-4.5% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-08 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-07 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-06 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-05 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-04 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-05-01 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-30 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-29 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-28 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-27 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-24 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-23 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-22 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-21 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-20 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-17 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5
2026-04-16 C 2/5 1/5 1/5 1/5 1/5 1/5 5/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
7
Total invested
847.1K
Insider transactions (90d)
0
Beneficial owners (>5%)
27
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Abigail P. Johnson 3.26M 14.67% 3.26M IN Delaware 2024-04-10
2 FMR LLC 3.26M 14.67% 3.26M 3.26M HC Delaware 2024-04-10
3 Kristina Burow 2.70M 12.10% 5.9K 2.69M 5.9K 2.69M IN States 2024-10-29
4 ARCH Venture Fund IX Overage, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
5 ARCH Venture Fund IX, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
6 ARCH Venture Fund X Overage, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
7 ARCH Venture Partners IX Overage, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
8 ARCH Venture Partners IX, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
9 ARCH Venture Partners X Overage, L.P. 2.69M 12.10% 2.69M 2.69M PN Delaware 2024-10-29
10 ARCH Venture Partners X, LLC 2.69M 12.10% 2.69M 2.69M OO Delaware 2024-10-29
11 Clinton Bybee 2.69M 12.10% 2.69M 2.69M IN States 2024-10-29
12 Keith Crandell 2.69M 12.10% 2.69M 2.69M IN States 2024-10-29
13 Robert Nelsen 2.69M 12.10% 2.69M 2.69M IN States 2024-10-29
14 Steven Gillis 2.69M 12.10% 2.69M 2.69M IN States 2024-10-29
15 Peter Kolchinsky 2.18M 9.80% 2.18M 2.18M HC, IN Delaware 2024-04-12
16 RA Capital Management, L.P. 2.18M 9.80% 2.18M 2.18M IA, PN Delaware 2024-04-12
17 Rajeev Shah 2.18M 9.80% 2.18M 2.18M HC, IN Delaware 2024-04-12
18 RA Capital Healthcare Fund, L.P. 1.88M 8.50% 1.88M 1.88M PN Delaware 2024-04-12
19 Bayer Aktiengesellschaft 1.62M 7.30% 1.62M HC, CO Citizenship or Place of Organization 2024-04-09
20 Bayer HealthCare LLC 1.62M 7.30% 1.62M CO Citizenship or Place of Organization 2024-04-09
21 Bayer US Holding LP 1.62M 7.30% 1.62M PN Citizenship or Place of Organization 2024-04-09
22 Bayer World Investments B.V. 1.62M 7.30% 1.62M CO Citizenship or Place of Organization 2024-04-09
23 Costas Constantinides 1.23M 5.50% 1.23M IN Luxembourg 2024-04-12
24 Ian Charoub 1.23M 5.50% 1.23M IN Luxembourg 2024-04-12
25 Nextech VI GP S.à. r.l. 1.23M 5.50% 1.23M 1.23M OO Luxembourg 2024-04-12
26 Nextech VI Oncology SCSp 1.23M 5.50% 1.23M 1.23M PN Luxembourg 2024-04-12
27 Rocco Sgobbo 1.23M 5.50% 1.23M IN Luxembourg 2024-04-12

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
7
-28 vs prev Q
New positions
5
Closed positions
33
Increased
6
Reduced
1
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 FMR LLC 2.68M -414.0K (-13.4%) 3.22M -589.8K (-15.5%) 11.99% -1.868 pp 0.00% +0.000 pp USD13.31 -91.0% 8 qtrs
2 CITADEL ADVISORS LLC 1.35M +477.5K (+54.5%) 1.62M +546.7K (+50.7%) 6.05% +2.128 pp 0.00% +0.000 pp USD7.85 -84.7% 8 qtrs
3 STONEPINE CAPITAL MANAGEMENT, LLC 710.1K +296.6K (+71.7%) 852.1K +343.5K (+67.6%) 3.17% +1.323 pp 0.62% +0.209 pp USD1.18 +1.7% 3 qtrs
4 SECTORAL ASSET MANAGEMENT INC 678.6K +— (+0.0%) 814.3K -20.4K (-2.4%) 3.03% -0.004 pp 0.65% +0.138 pp USD13.54 -91.1% 8 qtrs
5 VANGUARD GROUP INC 662.8K +93.1K (+16.3%) 795.3K +94.6K (+13.5%) 2.96% +0.413 pp 0.00% +0.000 pp USD2.97 -59.6% 8 qtrs
6 WELLINGTON MANAGEMENT GROUP LLP 556.2K +— (+0.0%) 667.5K -16.7K (-2.4%) 2.48% -0.003 pp 0.00% +0.000 pp USD13.54 -91.1% 8 qtrs
7 RENAISSANCE TECHNOLOGIES LLC 341.4K +117.8K (+52.7%) 409.7K +134.7K (+49.0%) 1.53% +0.525 pp 0.00% +0.000 pp USD1.16 +3.4% 7 qtrs
8 ALYESKA INVESTMENT GROUP, L.P. 300.0K +— (+0.0%) 360.0K -9.0K (-2.4%) 1.34% -0.002 pp 0.00% 0.000 pp USD11.98 -90.0% 8 qtrs
9 RBF CAPITAL, LLC 200.0K +— (+0.0%) 240.0K -6.0K (-2.4%) 0.89% -0.001 pp 0.01% 0.000 pp USD1.01 +18.8% 3 qtrs
10 NORTHERN TRUST CORP 189.5K -1.3K (-0.7%) 227.4K -7.3K (-3.1%) 0.85% -0.007 pp 0.00% +0.000 pp USD2.05 -41.5% 6 qtrs
11 ENSIGN PEAK ADVISORS, INC 187.5K +— (+0.0%) 225.0K -5.6K (-2.4%) 0.84% -0.001 pp 0.00% +0.000 pp USD13.54 -91.1% 8 qtrs
12 SIO CAPITAL MANAGEMENT, LLC 163.7K +— (+0.0%) 196.4K -4.9K (-2.4%) 0.73% -0.001 pp 0.03% -0.020 pp USD12.33 -90.3% 8 qtrs
13 MILLENNIUM MANAGEMENT LLC 135.4K -28.7K (-17.5%) 162.5K -39.3K (-19.5%) 0.60% -0.129 pp 0.00% +0.000 pp USD1.01 +18.8% 3 qtrs
14 LANDSCAPE CAPITAL MANAGEMENT, L.L.C. 127.6K +127.6K (+100.0%) 153.2K +153.2K (+100.0%) 0.57% +0.570 pp 0.01% +0.010 pp USD1.20 +0.0% 1 qtrs NEW
15 GEODE CAPITAL MANAGEMENT, LLC 94.1K -8.2K (-8.0%) 112.9K -12.9K (-10.2%) 0.42% -0.037 pp 0.00% +0.000 pp USD2.50 -52.0% 7 qtrs
16 BLACKROCK, INC. 67.0K +1.7K (+2.6%) 80.5K +47.0 (+0.1%) 0.30% +0.007 pp 0.00% +0.000 pp USD3.17 -62.1% 6 qtrs
17 GSA CAPITAL PARTNERS LLP 62.5K +62.5K (+100.0%) 75.0K +75.0K (+100.0%) 0.28% +0.279 pp 0.01% +0.007 pp USD1.20 +0.0% 1 qtrs NEW
18 BRIDGEWAY CAPITAL MANAGEMENT, LLC 50.5K +— (+0.0%) 60.6K -1.5K (-2.4%) 0.23% 0.000 pp 0.00% 0.000 pp USD1.01 +18.8% 6 qtrs
19 WALLEYE CAPITAL LLC 39.6K +— (+0.0%) 47.5K -1.2K (-2.4%) 0.18% 0.000 pp 0.00% +0.000 pp USD4.19 -71.4% 7 qtrs
20 XTX TOPCO LTD 39.6K +10.5K (+36.1%) 47.5K +11.7K (+32.8%) 0.18% +0.047 pp 0.00% -0.001 pp USD1.30 -7.7% 4 qtrs
21 CITIGROUP INC 25.1K +25.1K (+100.0%) 30.1K +30.1K (+100.0%) 0.11% +0.112 pp 0.00% +0.000 pp USD1.20 +0.0% 7 qtrs
22 QUBE RESEARCH & TECHNOLOGIES LTD 18.7K +660.0 (+3.7%) 22.4K +250.0 (+1.1%) 0.08% +0.003 pp 0.00% +0.000 pp USD1.02 +17.6% 3 qtrs
23 STATE STREET CORP 16.0K +— (+0.0%) 19.2K -479.0 (-2.4%) 0.07% 0.000 pp 0.00% +0.000 pp USD3.40 -64.7% 7 qtrs
24 JANE STREET GROUP, LLC 13.3K +13.3K (+100.0%) 16.0K +16.0K (+100.0%) 0.06% +0.060 pp 0.00% +0.000 pp USD1.20 +0.0% 1 qtrs NEW
25 MORGAN STANLEY 13.0K -2.5K (-16.1%) 15.6K -3.5K (-18.2%) 0.06% -0.011 pp 0.00% +0.000 pp USD3.69 -67.5% 7 qtrs
26 ABEL HALL, LLC 12.9K -60.0 (-0.5%) 15.4K -460.0 (-2.9%) 0.06% 0.000 pp 0.00% -0.003 pp USD1.01 +18.8% 3 qtrs
27 ACADIAN ASSET MANAGEMENT LLC 12.6K -1.1K (-8.3%) 14.0K -2.0K (-12.5%) 0.06% -0.005 pp 0.00% +0.000 pp USD2.90 -58.6% 5 qtrs
28 11.3K +11.3K (+100.0%) 13.6K +13.6K (+100.0%) 0.05% +0.051 pp 0.01% +0.008 pp USD1.20 +0.0% 1 qtrs NEW
29 BANK OF AMERICA CORP /DE/ 7.8K +19.0 (+0.2%) 9.3K -209.0 (-2.2%) 0.03% +0.000 pp 0.00% +0.000 pp USD3.60 -66.7% 7 qtrs
30 TOWER RESEARCH CAPITAL LLC (TRC) 5.8K +3.2K (+123.8%) 7.0K +3.8K (+118.4%) 0.03% +0.014 pp 0.00% +0.000 pp USD2.00 -40.0% 7 qtrs
31 BNP PARIBAS ARBITRAGE, SNC 176.00 -173.0 (-49.6%) 211.00 -218.0 (-50.8%) 0.00% -0.001 pp 0.00% +0.000 pp USD3.48 -65.5% 7 qtrs
32 JPMORGAN CHASE & CO 169.00 +169.0 (+100.0%) 203.00 +203.0 (+100.0%) 0.00% +0.001 pp 0.00% +0.000 pp USD1.20 +0.0% 7 qtrs
33 OPTIVER HOLDING B.V. 168.00 +— (+0.0%) 202.00 -5.0 (-2.4%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.23 -2.4% 2 qtrs
34 UBS GROUP AG 23.00 +22.0 (+2,200.0%) 27.00 +26.0 (+2,600.0%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.26 -4.8% 7 qtrs
35 BARCLAYS PLC 2.00 -8.6K (-100.0%) 2.00 -30.0K (-100.0%) 0.00% -0.039 pp 0.00% +0.000 pp USD1.00 +20.0% 8 qtrs
36 SQUAREPOINT OPS LLC -50.8K (-100.0%) -62.4K (-100.0%) 0.00% -0.227 pp 0.00% 0.000 pp USD 8 qtrs SOLD
37 REDMILE GROUP, LLC -245.5K (-100.0%) -301.9K (-100.0%) 0.00% -1.098 pp 0.00% -0.029 pp USD 8 qtrs SOLD
38 ALMITAS CAPITAL LLC -86.8K (-100.0%) -106.8K (-100.0%) 0.00% -0.388 pp 0.00% -0.024 pp USD 5 qtrs SOLD
39 NEXTECH INVEST, LTD. -1.2M (-100.0%) -1.5M (-100.0%) 0.00% -5.493 pp 0.00% -0.230 pp USD 4 qtrs SOLD
40 GOLDMAN SACHS GROUP INC -14.3K (-100.0%) -17.6K (-100.0%) 0.00% -0.064 pp 0.00% +0.000 pp USD 6 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 12 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.01% 141.8K 0.60%
2 Vanguard Extended Market ETF VXF 0.00% 215.4K 0.05%
3 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 1.4K 0.03%
4 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 3.8K 0.17%
5 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 277.47 0.17%
6 Vanguard Total Stock Market ETF VTI 0.00% 641.9K 0.03%
7 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 1.4K 0.22%
8 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 765.77 0.22%
9 Vanguard Balanced ETF Portfolio VBAL.TO 0.00% 309.55 0.22%
10 Vanguard Conservative ETF Portfolio VCNS.TO 0.00% 34.08 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
6
Sells
0
Shares acquired
104.0K
Shares disposed
Cash buys
Cash sales
Net activity
+104,000
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-01-23 Oien Jessica Officer A-Award A Stock Option (right to buy) 220,000 1.26 277.2K 220,000 D
2026-01-23 Hornby Zachary Director / Officer A-Award A Stock Option (right to buy) 600,000 1.26 756.0K 600,000 D
2026-01-23 Hassig Christian Officer A-Award A Stock Option (right to buy) 230,000 1.26 289.8K 230,000 D
2026-01-23 HINKLE DAVID A Officer A-Award A Stock Option (right to buy) 140,000 1.26 176.4K 140,000 D
2026-01-23 Doebele Robert Officer A-Award A Stock Option (right to buy) 230,000 1.26 289.8K 230,000 D
2025-06-23 Whiting Nancy Director A-Award A Stock Option (right to buy) 16,000 1.03 16.5K 16,000 D
2025-06-23 Lim Jonathan E Director A-Award A Stock Option (right to buy) 24,000 1.03 24.7K 24,000 D
2025-06-23 Lew Jennifer Director A-Award A Stock Option (right to buy) 16,000 1.03 16.5K 16,000 D
2025-06-23 Christensen James Director A-Award A Stock Option (right to buy) 16,000 1.03 16.5K 16,000 D
2025-06-23 Burow Kristina Director / 10% Owner A-Award A Stock Option (right to buy) 16,000 1.03 16.5K 16,000 D
2025-06-23 Brennan Christine Director A-Award A Stock Option (right to buy) 16,000 1.03 16.5K 16,000 D
2020-01-15 Soloway Thomas P Officer D-Return D Stock Option (Right to Buy) 65,000 24.74 1.61M 0
2020-01-15 Patterson Matthew R Director / Officer U-Tender D Common Stock 171,814 60.00 10.31M 0
2020-01-15 Holles Natalie C. Officer D-Return D Stock Option (Right to Buy) 25,000 36.39 909.8K 0
2020-01-15 Goldberg Mark Alan Director D-Return D Stock Option (Right to Buy) 10,000 38.65 386.5K 0
2020-01-15 Conner Edward R. Officer U-Tender D Common Stock 24,584 60.00 1.48M 0
2020-01-08 Soloway Thomas P Officer M-Exempt D Stock Option (right to buy) 144,669 2.76 400.0K 3,829
2020-01-08 Patterson Matthew R Director / Officer M-Exempt A Common Stock 74,297 2.19 162.7K 237,968
2019-12-26 Patterson Matthew R Director / Officer G-Gift D Common Stock 12,500 0.00 98,920
2019-12-12 Soloway Thomas P Officer F-InKind D Common Stock 8,681 59.37 515.4K 12,633
2019-12-12 Holles Natalie C. Officer F-InKind D Common Stock 88,928 59.37 5.28M 104,439
2019-12-12 Conner Edward R. Officer F-InKind D Common Stock 5,416 59.37 321.5K 24,584
2019-12-05 Soloway Thomas P Officer F-InKind D Common Stock 505 59.21 29.9K 21,314
2019-12-05 Patterson Matthew R Director / Officer F-InKind D Common Stock 1,974 59.21 116.9K 111,420
2019-12-05 Holles Natalie C. Officer F-InKind D Common Stock 505 59.21 29.9K 54,704
2019-11-08 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 14,426 9.50 137.0K 155,393
2019-09-05 Soloway Thomas P Officer F-InKind D Common Stock 505 31.02 15.7K 21,819
2019-09-05 Patterson Matthew R Director / Officer F-InKind D Common Stock 1,974 31.02 61.2K 113,394
2019-09-05 Holles Natalie C. Officer F-InKind D Common Stock 505 31.02 15.7K 55,209
2019-08-12 Patterson Matthew R Director / Officer S-Sale D Common Stock 19,000 34.02 646.3K 116,368
2019-07-15 Conner Edward R. Officer A-Award A Stock Option (Right to Buy) 90,000 36.08 3.25M 90,000
2019-06-05 Soloway Thomas P Officer F-InKind D Common Stock 1,009 37.31 37.6K 22,324
2019-06-05 Patterson Matthew R Director / Officer F-InKind D Common Stock 3,332 37.31 124.3K 115,368
2019-06-05 Holles Natalie C. Officer F-InKind D Common Stock 1,009 37.31 37.6K 55,714
2019-02-25 Patterson Matthew R Director / Officer M-Exempt A Common Stock 17,000 0.78 13.3K 135,700
2019-02-06 Soloway Thomas P Officer A-Award A Common Stock 23,333 0.00 23,333
2019-02-06 Patterson Matthew R Director / Officer A-Award A Common Stock 63,700 0.00 118,700
2019-02-06 Holles Natalie C. Officer A-Award A Common Stock 23,333 0.00 56,723
2019-02-06 Goldberg Mark Alan Director A-Award A Stock Option (right to buy) 16,200 24.74 400.8K 16,200
2019-01-24 Holles Natalie C. Officer M-Exempt D Stock Option (right to buy) 8,300 2.76 22.9K 156,429
2018-12-06 Patterson Matthew R Director / Officer M-Exempt A Common Stock 40,000 0.78 31.2K 55,000
2018-10-01 Patterson Matthew R Director / Officer M-Exempt A Common Stock 2,144 0.78 1.7K 17,144
2018-09-24 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 15,000 0.78 11.7K 92,702
2018-09-18 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 12,952 2.19 28.4K 128,345
2018-07-05 Patterson Matthew R Director / Officer S-Sale D Common Stock 23,147 40.04 926.9K 0
2018-07-03 Patterson Matthew R Director / Officer S-Sale D Common Stock 26,901 40.05 1.08M 0
2018-07-02 Patterson Matthew R Director / Officer M-Exempt A Common Stock 1,401 0.78 1.1K 1,401
2018-06-08 Goldberg Mark Alan Director A-Award A Stock Option (right to buy) 10,000 38.65 386.5K 10,000
2018-06-01 Holles Natalie C. Officer M-Exempt D Stock Option (right to buy) 5,090 2.76 14.1K 164,729
2018-05-21 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 20,300 0.78 15.8K 178,750
2018-05-07 Holles Natalie C. Officer A-Award A Stock Option (right to buy) 25,000 36.39 909.8K 25,000
2018-04-02 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 700 0.78 546.00 199,050
2018-03-12 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 16,937 34.92 591.4K 3,539,997
2018-03-09 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 21,300 34.67 738.5K 3,616,700
2018-03-08 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 58,428 34.06 1.99M 3,638,000
2018-03-06 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 11,372 33.03 375.6K 3,696,428
2018-03-05 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 200 36.06 7.2K 3,707,800
2018-03-02 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 386,080 35.06 13.54M 3,743,558
2018-01-18 Goldberg Mark Alan Director A-Award A Stock Option (right to buy) 4,500 38.00 171.0K 4,500
2018-01-01 Goldberg Mark Alan Director A-Award A Stock Option (right to buy) 18,000 33.91 610.4K 18,000
2017-12-11 Goldberg Mark Alan Director D Common Stock 0 0.00 1,500
2017-11-16 Soloway Thomas P Officer A-Award A Stock Option (right to buy) 75,000 27.39 2.05M 75,000
2017-11-16 Patterson Matthew R Director / Officer A-Award A Stock Option (right to buy) 225,000 27.39 6.16M 225,000
2017-11-16 Holles Natalie C. Officer A-Award A Stock Option (right to buy) 100,000 27.39 2.74M 100,000
2017-10-02 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 10,000 0.78 7.8K 199,750
2017-09-29 ORBIMED ADVISORS LLC 10% Owner S-Sale D Common Stock 672,000 28.25 18.98M 4,129,638
2017-09-18 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 8,458 0.78 6.6K 209,750
2017-09-15 Patterson Matthew R Director / Officer M-Exempt D Stock Option (right to buy) 1,542 0.78 1.2K 218,208
2017-09-07 ORBIMED ADVISORS LLC 10% Owner X-InTheMoney A Common Stock 5,000 15.03 75.2K 4,806,638
2017-07-13 Patterson Matthew R Director / Officer S-Sale D Common Stock 12,150 20.00 243.1K 186,814
2017-07-12 Patterson Matthew R Director / Officer S-Sale D Common Stock 2,850 20.00 57.0K 198,964
2017-05-31 Holles Natalie C. Officer M-Exempt D Stock Option (right to buy) 20,000 2.76 55.2K 169,819
2017-04-24 5AM Partners III, LLC 10% Owner P-Purchase A Common Stock 168,082 14.50 2.44M 2,500,113
2017-01-25 Soloway Thomas P Officer A-Award A Stock Option (right to buy) 80,000 15.26 1.22M 80,000
2017-01-25 Patterson Matthew R Director / Officer A-Award A Stock Option (right to buy) 200,000 15.26 3.05M 200,000
2017-01-25 Holles Natalie C. Officer A-Award A Stock Option (right to buy) 115,000 15.26 1.75M 115,000
2016-08-24 Woiwode Thomas Director A-Award A Stock Option (right to buy) 18,000 15.03 270.5K 18,000
2016-08-24 SILVERSTEIN JONATHAN Director / 10% Owner A-Award A Stock Option (right to buy) 18,000 15.03 270.5K 18,000
2016-07-25 Woiwode Thomas Director C-Conversion D Series A Preferred Stock 6,811 0.00 0
2016-07-25 SILVERSTEIN JONATHAN Director / 10% Owner C-Conversion D Series C Preferred Stock 332,766 0.00 0
2016-07-25 ORBIMED ADVISORS LLC Director / 10% Owner C-Conversion D Series Seed Preferred Stock 627,867 0.00 0
2016-07-25 Flynn James E 10% Owner C-Conversion D Series C Convertible Preferred Stock 99,830 0.00 0
2016-07-19 Woiwode Thomas Director I Series A Preferred Stock 6,811 0.00 0
2016-07-19 Versant Ventures IV, LLC 10% Owner D No securities beneficially held 0 0.00 0
2016-07-19 Soloway Thomas P Officer D Stock Option (right to buy) 189,819 2.77 525.8K 0
2016-07-19 SILVERSTEIN JONATHAN Director / 10% Owner I Series C Preferred Stock 332,766 0.00 0
2016-07-19 Patterson Matthew R Director / Officer I Common Stock 0 0.00 201,814
2016-07-19 ORBIMED ADVISORS LLC Director / 10% Owner I Series A Preferred Stock 2,511,441 0.00 0
2016-07-19 Holles Natalie C. Officer D Stock Option (right to buy) 189,819 2.77 525.8K 0
2016-07-19 Flynn James E 10% Owner I Series B Convertible Preferred Stock 267,998 0.00 0
2016-07-19 5AM Partners III, LLC 10% Owner I Series C Preferred Stock 6,688 0.00 0

Executive team

Top executives
Shares Outstanding
22.42M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Zachary D. Hornby President, Chief Executive Officer, and Director 638.0K 628.4K 333.4K 3.5K 1.60M 39.19%
2 2025 Robert Doebele, M.D., Ph.D. Chief Medical Officer 458.5K 333.0K 183.3K 3.5K 978.3K 34.04%
3 2025 Christian Hassig, Ph.D. Chief Scientific Officer 478.3K 202.4K 191.2K 3.5K 875.4K 23.12%
4 2024 Zachary D. Hornby President, Chief Executive Officer, and Director 594.6K 5.18M 281.6K 3.5K 6.05M 85.47%
5 2024 Christian Hassig, Ph.D. Chief Scientific Officer 453.1K 1.54M 158.3K 3.5K 2.16M 71.48%
6 2024 Klaus Wagner, M.D., Ph.D. Former Chief Medical Officer 491.8K 1.35M 1.85M 73.35%
7 2024 Jami Rubin Former Chief Financial Officer 354.1K 1.03M 352.2K 1.74M 59.43%
8 2024 Neil Abdollahian Former Chief Business Officer 403.7K 740.6K 3.5K 1.15M 64.53%
9 2023 Zachary D. Hornby President, Chief Executive Officer, and Director 495.0K 1.65M 222.8K 3.3K 2.37M 69.61%
10 2023 Klaus Wagner, M.D., Ph.D. Former Chief Medical Officer 465.8K 363.6K 163.0K 3.3K 995.8K 36.51%
11 2023 Christian Hassig, Ph.D. Chief Scientific Officer 415.0K 340.0K 145.3K 3.3K 903.5K 37.63%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2025-04-29 DEFA14A
2025-04-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-08 8-K
2026-05-08 10-Q
2026-04-28 DEFA14A
2026-04-28 DEF 14A
2026-04-28 ARS
2026-04-13 8-K
2026-03-09 8-K
2026-03-09 10-K
2026-02-17 SC 13G/A
2026-02-05 SC 13G/A

Executive team

NameTitleCompensationGender
Zachary Hornby Chief Executive Officer, President & Director 974.9K male
Robert C. Doebele Chief Medical Officer 690.3K
Christian Hassig Chief Scientific Officer 673.0K
Amy Berkley Senior Vice President of Program Team female
Meredith Wesley Chief Human Resources Officer female
Jessica Oien Chief Legal Officer & Corporate Secretary female
David Hinkle Senior Vice President of Finance, Controller & Corporate Treasurer male
James L. Freddo Interim Chief Medical Officer
ESG Rating
B
BIOTECHNOLOGY
2026
E (Environmental)
72.9 / 56.3
Company / Sector avg.
S (Social)
64.0 / 62.4
Company / Sector avg.
G (Governance)
67.5 / 60.9
Company / Sector avg.
ESG Total
68.1 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits