Subscribe

Biomea Fusion, Inc. (BMEA)

USD1.29 -0.01 (-0.39%)
US NASDAQ Healthcare Biotechnology
Address 900 Middlefield Road 94063
Redwood City, CA, US
CEO Michael J. Hitchcock
IPO 2021-04-16
CIK 1840439 ISIN US09077A1060

Explore sections of this company profile

Description

Biomea Fusion, Inc. is a biopharmaceutical firm dedicated to discovering and developing innovative covalent small molecule therapies. These treatments are specifically designed for individuals suffering from genetically defined cancers and various metabolic ailments. The company's primary drug candidate, BMF-219, is a potent and selective covalent inhibitor of menin, engineered for oral administration. Menin plays a crucial role as a transcriptional regulator in the abnormal signaling pathways found across numerous cancer types. Established in 2017, Biomea Fusion's operations are headquartered in Redwood City, California.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
Loading outlook…
Loading forecast...
Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
Loading risk profile…
Price Chart
Averages
Trend
Price
Levels
Draw
USD1.29 -0.01 (-0.39%)
Loading historical data…
Volume Profile
Loading…
Liquidity & share structure
Average Volume
1M
Beta
-0.32
Float Shares
52.34M
Free Float %
88.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.64% -1.25% -15.51% +26.40% +15.33% +27.42% -10.73% -95.35% -90.05% -90.71% -90.71%
Rolling Volatility
Loading…
Drawdown
Loading…
Relative Strength
Loading…
Monthly Returns Heatmap
From To
Loading…
Annual Monthly Returns
Loading…
Daily Returns Distribution
vs.
Loading histogram data…

Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (13 ratings, all time) Buy
Price Targets & DCF
Current price
1.29
Low 10.00 +678.2%
Consensus 20.20 +1,472.0%
Median 19.00 +1,378.6%
High 40.00 +3,012.8%
DCF (Unlevered) 0.98 -23.8%
DCF (Levered) 1.04 -19.2%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 88% Bullish
Rating 2026-05 Change
Strong Buy 2 +1
Buy 5 0
Hold 0 0
Sell 0 0
Strong Sell 1 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter
Last Year
All Time 9
16.33
+1,170.8%
Quality scores
Altman Z-Score
-15.33
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
  • EPS growth Biotechnology: +29.7%
    +69.2% Q1'26: +78.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
  • Share dilution Biotechnology: -3.4%
    +44.7% Q1'26: +97.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.02× Q1'26: -0.02× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.34) × ERP
WACC = 98% × Ke + 2% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.98 Current price: 1.29
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
5 EPS Ana.
Dec 2027
8 Rev. Ana.
5 EPS Ana.
Dec 2028
6 Rev. Ana.
5 EPS Ana.
Dec 2029
5 Rev. Ana.
1 EPS Ana.
Dec 2030
3 Rev. Ana.
1 EPS Ana.
Revenue
est: 10.00M (-100.0%)
est: 2.50M (-100.0%)
3.00M
3.00M – 3.00M
+20.0% YoY
1.12M
1.12M – 1.12M
-62.8% YoY
4.13M
4.13M – 4.13M
+269.7% YoY
616.00M
616.00M – 616.00M
+14,816.1% YoY
107.05M
107.05M – 107.05M
-82.6% YoY
EBITDA
-142.32M
-79.90M
— – —
— – —
— – —
— – —
— – —
EBIT
-144.07M
-81.31M
— – —
— – —
— – —
— – —
— – —
Net Income
-138.43M
est: -199.16M (+30.5%)
-61.80M
est: -76.64M (+19.4%)
-70.68M
-72.87M – -31.47M
+7.8% YoY
-106.37M
-124.75M – -30.36M
-50.5% YoY
-72.94M
-108.90M – -36.98M
+31.4% YoY
-53.27M
-53.27M – -53.27M
+27.0% YoY
-4.18M
-4.18M – -4.18M
+92.2% YoY
SGA
25.99M
19.33M
— – —
— – —
— – —
— – —
— – —
EPS
-3.83
est: -3.89 (+1.5%)
-1.18
est: -1.53 (+23.0%)
-0.95
-1.40 – -0.60
+37.9% YoY
-1.19
-2.39 – -0.58
-25.1% YoY
-1.10
-2.09 – -0.71
+7.6% YoY
-1.02
-1.02 – -1.02
+7.2% YoY
-0.08
-0.08 – -0.08
+92.2% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-28 D. Boral Capital Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C 2/5 3/5 1/5 1/5 3/5 1/5 1/5
2026-05-08 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-28 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-27 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history)

Owner's Earnings history not available.

Owner alignment
Owner's Earnings TTM
OE per share TTM
Owner's Yield
Maintenance CapEx ratio
Maint CapEx / Avg PPE

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
16
Total invested
9.60M
Insider transactions (90d)
0
Beneficial owners (>5%)
27
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Thomas Butler 5.37M 18.30% 528.0K 4.85M 528.0K 4.85M IN 2022-02-11
2 Rainer M. Erdtmann 4.99M 17.10% 141.6K 4.85M 141.6K 4.85M IN 2022-02-11
3 STATE STREET CORPORATION 4.49M 12.50% 4.41M 4.49M HC BOSTON, MASSACHUSETTS 2024-04-10
4 Point Sur Investors, LLC 4.37M 15.00% 4.37M 4.37M PN 2022-02-11
5 SSGA FUNDS MANAGEMENT, INC. 4.04M 11.25% 4.03M 4.04M IA BOSTON, MASSACHUSETTS 2024-04-10
6 EIN #00-0000000 3.53M 12.10% 3.53M 3.53M IA, HC Jersey, Channel Islands 2022-02-10
7 Bihua Chen 3.17M 11.03% 1.6K 3.17M 1.6K 3.17M IN United States 2021-04-30
8 Cormorant Asset Management, LP 3.17M 11.02% 3.17M 3.17M PN Delaware 2021-04-30
9 Benjamin Alexander Smith 2.74M 7.66% 2.74M IN Delaware 2024-02-08
10 Janaka Sheehan Maduraperuma 2.74M 7.66% 2.74M IN Delaware 2024-02-08
11 Laurion Capital Management LP 2.74M 7.66% 2.74M IA, PN Delaware 2024-02-08
12 (1) BlackRock, Inc. 2.16M 6.00% 2.13M 2.16M HC Delaware 2024-01-29
13 Baker Bros. Advisors (GP) LLC 2.10M 7.20% 2.10M 2.10M HC, OO Delaware 2023-02-14
14 Baker Bros. Advisors LP 2.10M 7.20% 2.10M 2.10M IA, PN Delaware 2023-02-14
15 Felix J. Baker 2.10M 7.20% 2.10M 2.10M HC, IN United States 2023-02-14
16 Julian C. Baker 2.10M 7.20% 2.10M 2.10M HC, IN United States 2023-02-14
17 Cormorant Private Healthcare Fund III, LP 1.72M 5.97% 1.72M 1.72M PN Delaware 2021-04-30
18 Cormorant Private Healthcare GP III, LLC 1.72M 5.97% 1.72M 1.72M OO Delaware 2021-04-30
19 (1)Names of reporting persons. BlackRock, Inc. 1.67M 5.80% 1.67M 1.67M HC Delaware 2022-02-04
20 Cormorant Global Healthcare GP, LLC 1.40M 4.85% 1.40M 1.40M OO Delaware 2021-04-30
21 Cormorant Global Healthcare Master Fund, LP 1.40M 4.85% 1.40M 1.40M PN Cayman Islands 2021-04-30
22 Boxer Asset Management Inc. 1.19M 4.10% 1.19M 1.19M CO 2022-02-14
23 Boxer Capital, LLC 1.19M 4.10% 1.19M 1.19M OO 2022-02-14
24 Joe Lewis 1.19M 4.10% 1.19M 1.19M IN 2022-02-14
25 Point Sur Investors Fund I, L.P. 480.8K 1.70% 480.8K 480.8K PN 2022-02-11
26 Aaron I. Davis 73.2K 0.30% 73.2K 73.2K OO 2022-02-14
27 MVA Investors, LLC 73.2K 0.30% 73.2K 73.2K OO 2022-02-14

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
16
-50 vs prev Q
New positions
4
Closed positions
48
Increased
7
Reduced
2
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 FMR LLC 8.81M +1.2M (+15.7%) 10.93M -4.5M (-29.0%) 21.69% +2.945 pp 0.00% 0.000 pp USD15.69 -92.1% 19 qtrs
2 VANGUARD GROUP INC 2.97M +798.0K (+36.8%) 3.68M -703.2K (-16.0%) 7.31% +1.964 pp 0.00% +0.000 pp USD8.32 -85.1% 19 qtrs
3 AISLING CAPITAL MANAGEMENT LP 2.05M +— (+0.0%) 2.54M -1.6M (-38.6%) 5.04% +0.000 pp 0.53% -0.376 pp USD7.18 -82.7% 19 qtrs
4 WOODLINE PARTNERS LP 1.30M +— (+0.0%) 1.61M -1.0M (-38.6%) 3.20% +0.000 pp 0.01% -0.006 pp USD5.19 -76.1% 12 qtrs
5 MARSHALL WACE, LLP 1.16M +865.6K (+293.7%) 1.44M +843.5K (+141.7%) 2.86% +2.131 pp 0.00% +0.001 pp USD1.65 -24.8% 9 qtrs
6 UBS GROUP AG 785.3K +785.3K (+100.0%) 973.8K +973.8K (+100.0%) 1.93% +1.933 pp 0.00% +0.000 pp USD1.24 +0.0% 1 qtrs NEW
7 BLACKROCK, INC. 632.1K -269.5K (-29.9%) 783.8K -1.0M (-57.0%) 1.56% -0.663 pp 0.00% +0.000 pp USD8.77 -85.9% 6 qtrs
8 631.5K +631.5K (+100.0%) 783.0K +783.0K (+100.0%) 1.55% +1.554 pp 0.03% +0.028 pp USD1.24 +0.0% 1 qtrs NEW
9 MARINER, LLC 585.6K +346.7K (+145.1%) 726.2K +243.5K (+50.5%) 1.44% +0.853 pp 0.00% +0.000 pp USD1.56 -20.5% 2 qtrs
10 GEODE CAPITAL MANAGEMENT, LLC 562.9K +116.0K (+26.0%) 698.1K -204.8K (-22.7%) 1.39% +0.286 pp 0.00% +0.000 pp USD8.34 -85.1% 19 qtrs
11 RENAISSANCE TECHNOLOGIES LLC 478.6K -117.3K (-19.7%) 593.5K -610.2K (-50.7%) 1.18% -0.289 pp 0.00% -0.001 pp USD2.02 -38.6% 7 qtrs
12 SUSQUEHANNA INTERNATIONAL GROUP, LLP 478.0K +139.4K (+41.2%) 592.8K -91.3K (-13.3%) 1.18% +0.343 pp 0.00% +0.000 pp USD2.00 -38.0% 14 qtrs
13 TWO SIGMA INVESTMENTS, LP 423.5K -139.5K (-24.8%) 525.1K -612.1K (-53.8%) 1.04% -0.343 pp 0.00% -0.001 pp USD3.66 -66.1% 13 qtrs
14 MORGAN STANLEY 372.6K -70.4K (-15.9%) 462.1K -432.9K (-48.4%) 0.92% -0.173 pp 0.00% +0.000 pp USD11.40 -89.1% 19 qtrs
15 FEDERATED HERMES, INC. 311.1K -260.9K (-45.6%) 385.8K -769.8K (-66.6%) 0.77% -0.642 pp 0.00% -0.001 pp USD2.48 -50.0% 5 qtrs
16 XTX TOPCO LTD 261.1K -4.2K (-1.6%) 323.7K -212.2K (-39.6%) 0.64% -0.010 pp 0.01% -0.019 pp USD1.90 -34.7% 7 qtrs
17 SUPERSTRING CAPITAL MANAGEMENT LP 250.0K +— (+0.0%) 310.0K -195.0K (-38.6%) 0.62% +0.000 pp 0.17% -0.332 pp USD1.80 -31.1% 3 qtrs
18 NORTHERN TRUST CORP 209.0K +21.3K (+11.4%) 259.1K -119.9K (-31.6%) 0.51% +0.053 pp 0.00% +0.000 pp USD10.97 -88.7% 19 qtrs
19 STATE STREET CORP 165.1K +25.0K (+17.8%) 204.7K -78.3K (-27.7%) 0.41% +0.062 pp 0.00% +0.000 pp USD10.69 -88.4% 19 qtrs
20 LMR PARTNERS LLP 150.0K +150.0K (+100.0%) 186.0K +186.0K (+100.0%) 0.37% +0.369 pp 0.00% +0.000 pp USD1.24 +0.0% 1 qtrs NEW
21 TWO SIGMA ADVISERS, LP 105.8K -160.9K (-60.3%) 131.2K -407.5K (-75.6%) 0.26% -0.396 pp 0.00% -0.001 pp USD3.98 -68.8% 10 qtrs
22 MAREX GROUP PLC 100.0K +— (+0.0%) 124.0K -78.0K (-38.6%) 0.25% +0.000 pp 0.00% -0.001 pp USD1.92 -35.4% 3 qtrs
23 SCULPTOR CAPITAL LP 84.8K +— (+0.0%) 105.2K -66.1K (-38.6%) 0.21% +0.000 pp 0.00% -0.001 pp USD15.30 -91.9% 8 qtrs
24 QUADRATURE CAPITAL LTD 69.9K -18.3K (-20.8%) 86.7K -92.9K (-51.7%) 0.17% -0.045 pp 0.00% -0.001 pp USD2.02 -38.6% 4 qtrs
25 JANE STREET GROUP, LLC 69.5K -11.7K (-14.5%) 86.2K -77.9K (-47.5%) 0.17% -0.029 pp 0.00% +0.000 pp USD2.96 -58.1% 12 qtrs
26 GOLDMAN SACHS GROUP INC 68.8K -197.2K (-74.1%) 85.3K -452.1K (-84.1%) 0.17% -0.485 pp 0.00% 0.000 pp USD7.60 -83.7% 17 qtrs
27 BRIDGEWAY CAPITAL MANAGEMENT, LLC 68.3K -2.0K (-2.8%) 84.7K -57.3K (-40.4%) 0.17% -0.005 pp 0.00% -0.001 pp USD5.74 -78.4% 6 qtrs
28 BARCLAYS PLC 59.0K +19.4K (+48.9%) 73.2K -327.0K (-81.7%) 0.15% +0.048 pp 0.00% 0.000 pp USD2.39 -48.1% 16 qtrs
29 GRIFFIN ASSET MANAGEMENT, INC. 58.3K -3.0K (-4.9%) 72.3K -51.5K (-41.6%) 0.14% -0.007 pp 0.01% -0.006 pp USD10.26 -87.9% 9 qtrs
30 JAIN GLOBAL LLC 55.2K +55.2K (+100.0%) 68.4K +68.4K (+100.0%) 0.14% +0.136 pp 0.00% +0.000 pp USD1.24 +0.0% 3 qtrs
31 ADAR1 CAPITAL MANAGEMENT, LLC 43.4K +43.4K (+100.0%) 53.8K +53.8K (+100.0%) 0.11% +0.107 pp 0.00% +0.004 pp USD1.24 +0.0% 1 qtrs NEW
32 CITIGROUP INC 39.9K +38.7K (+3,312.5%) 49.5K +47.1K (+1,994.2%) 0.10% +0.095 pp 0.00% +0.000 pp USD1.48 -16.2% 19 qtrs
33 TWO SIGMA SECURITIES, LLC 36.6K +36.6K (+100.0%) 45.4K +45.4K (+100.0%) 0.09% +0.090 pp 0.01% +0.006 pp USD1.24 +0.0% 1 qtrs NEW
34 MILLENNIUM MANAGEMENT LLC 25.7K +15.7K (+156.7%) 31.8K +11.6K (+57.6%) 0.06% +0.039 pp 0.00% +0.000 pp USD1.70 -27.1% 17 qtrs
35 DIMENSIONAL FUND ADVISORS LP 25.3K +— (+0.0%) 31.4K -19.8K (-38.7%) 0.06% +0.000 pp 0.00% +0.000 pp USD10.41 -88.1% 14 qtrs
36 PNC FINANCIAL SERVICES GROUP, INC. 24.0K +— (+0.0%) 29.8K -18.7K (-38.6%) 0.06% +0.000 pp 0.00% +0.000 pp USD7.70 -83.9% 9 qtrs
37 GSA CAPITAL PARTNERS LLP 22.7K +22.7K (+100.0%) 28.0K +28.0K (+100.0%) 0.06% +0.056 pp 0.00% +0.002 pp USD1.24 +0.0% 1 qtrs NEW
38 POINT72 ASSET MANAGEMENT, L.P. 17.3K +17.3K (+100.0%) 21.4K +21.4K (+100.0%) 0.04% +0.043 pp 0.00% +0.000 pp USD1.24 +0.0% 1 qtrs NEW
39 CREATIVE PLANNING 12.0K -228.0 (-1.9%) 14.9K -9.8K (-39.8%) 0.03% -0.001 pp 0.00% +0.000 pp USD4.21 -70.5% 7 qtrs
40 CFS INVESTMENT ADVISORY SERVICES, LLC 11.5K +— (+0.0%) 14.2K -2.5K (-15.1%) 0.03% +0.000 pp 0.00% 0.000 pp USD1.80 -31.1% 3 qtrs
41 ADVISOR GROUP HOLDINGS, INC. 8.0K +843.0 (+11.8%) 9.9K -4.5K (-31.1%) 0.02% +0.002 pp 0.00% +0.000 pp USD6.07 -79.6% 11 qtrs
42 SBI SECURITIES CO., LTD. 7.1K +1.0K (+16.5%) 8.8K -3.5K (-28.5%) 0.02% +0.003 pp 0.00% 0.000 pp USD2.22 -44.1% 5 qtrs
43 SIGNATUREFD, LLC 3.5K +— (+0.0%) 4.3K -2.8K (-39.1%) 0.01% +0.000 pp 0.00% +0.000 pp USD11.48 -89.2% 9 qtrs
44 PINNACLE WEALTH PLANNING SERVICES, INC. 3.3K +3.3K (+100.0%) 4.1K +4.1K (+100.0%) 0.01% +0.008 pp 0.00% +0.000 pp USD1.24 +0.0% 1 qtrs NEW
45 JPMORGAN CHASE & CO 3.3K +1.3K (+64.5%) 4.1K +40.0 (+1.0%) 0.01% +0.003 pp 0.00% +0.000 pp USD5.36 -76.9% 19 qtrs
46 QUEST PARTNERS LLC 3.3K +— (+0.0%) 4.1K -2.6K (-38.6%) 0.01% +0.000 pp 0.00% 0.000 pp USD2.13 -41.8% 9 qtrs
47 ROCKEFELLER CAPITAL MANAGEMENT L.P. 2.0K +— (+0.0%) 2.5K -1.6K (-38.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.02 -38.6% 2 qtrs
48 BANK OF AMERICA CORP /DE/ 1.3K -9.7K (-88.1%) 1.6K -20.6K (-92.7%) 0.00% -0.024 pp 0.00% +0.000 pp USD8.11 -84.7% 19 qtrs
49 RHUMBLINE ADVISERS 1.2K +— (+0.0%) 1.5K -936.0 (-38.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD16.11 -92.3% 11 qtrs
50 BNP PARIBAS ARBITRAGE, SNC 1.1K -772.0 (-42.3%) 1.3K -2.4K (-64.6%) 0.00% -0.002 pp 0.00% +0.000 pp USD2.49 -50.2% 5 qtrs
51 FORTITUDE FAMILY OFFICE, LLC 454.00 +158.0 (+53.4%) 563.00 -35.0 (-5.9%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.74 -28.7% 2 qtrs
52 GLOBAL RETIREMENT PARTNERS, LLC 375.00 +— (+0.0%) 465.00 -293.0 (-38.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.80 -31.1% 3 qtrs
53 GLEN EAGLE ADVISORS, LLC 250.00 +— (+0.0%) 310.00 -195.0 (-38.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD14.52 -91.5% 9 qtrs
54 NATIONAL BANK OF CANADA /FI/ 200.00 -123.4K (-99.8%) 248.00 -249.4K (-99.9%) 0.00% -0.304 pp 0.00% 0.000 pp USD1.80 -31.1% 3 qtrs
55 JONES FINANCIAL COMPANIES LLLP 128.00 +53.0 (+70.7%) 159.00 +1.0 (+0.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.78 -55.4% 5 qtrs
56 MAI CAPITAL MANAGEMENT 100.00 +— (+0.0%) 124.00 -78.0 (-38.6%) 0.00% +0.000 pp 0.00% +0.000 pp USD2.02 -38.6% 2 qtrs
57 COMERICA BANK 20.00 +— (+0.0%) 25.00 -15.0 (-37.5%) 0.00% +0.000 pp 0.00% +0.000 pp USD3.85 -67.8% 5 qtrs
58 WELLS FARGO & COMPANY/MN 1.00 +— (+0.0%) 1.00 -2.0 (-66.7%) 0.00% +0.000 pp 0.00% +0.000 pp USD10.00 -87.6% 17 qtrs
59 MIRAE ASSET GLOBAL INVESTMENTS CO., LTD. -2.3K (-100.0%) -4.6K (-100.0%) 0.00% -0.006 pp 0.00% +0.000 pp USD 11 qtrs SOLD
60 SQUAREPOINT OPS LLC -22.8K (-100.0%) -46.0K (-100.0%) 0.00% -0.056 pp 0.00% +0.000 pp USD 10 qtrs SOLD
61 CORMORANT ASSET MANAGEMENT, LP -3.6M (-100.0%) -7.2M (-100.0%) 0.00% -8.789 pp 0.00% -0.498 pp USD 19 qtrs SOLD
62 TOWER RESEARCH CAPITAL LLC (TRC) -7.2K (-100.0%) -14.5K (-100.0%) 0.00% -0.018 pp 0.00% 0.000 pp USD 19 qtrs SOLD
63 CITADEL ADVISORS LLC -179.8K (-100.0%) -363.2K (-100.0%) 0.00% -0.443 pp 0.00% 0.000 pp USD 19 qtrs SOLD
64 GROVE BANK & TRUST -2.9K (-100.0%) -5.8K (-100.0%) 0.00% -0.007 pp 0.00% -0.001 pp USD 9 qtrs SOLD
65 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. -10.4K (-100.0%) -21.1K (-100.0%) 0.00% -0.026 pp 0.00% -0.002 pp USD 14 qtrs SOLD
66 VANGUARD PERSONALIZED INDEXING MANAGEMENT, LLC -16.0K (-100.0%) -32.4K (-100.0%) 0.00% -0.040 pp 0.00% 0.000 pp USD 2 qtrs SOLD
67 VIRTU FINANCIAL LLC -19.1K (-100.0%) -39.0K (-100.0%) 0.00% -0.047 pp 0.00% -0.002 pp USD 2 qtrs SOLD
68 PHYSICIAN WEALTH ADVISORS, INC. -1.2K (-100.0%) -2.4K (-100.0%) 0.00% -0.003 pp 0.00% 0.000 pp USD 3 qtrs SOLD
69 HEIGHTS CAPITAL MANAGEMENT, INC -1.4M (-100.0%) -2.9M (-100.0%) 0.00% -3.538 pp 0.00% -0.796 pp USD 3 qtrs SOLD
70 EVERSOURCE WEALTH ADVISORS, LLC -177.0 (-100.0%) -357.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 5 qtrs SOLD
71 QUBE RESEARCH & TECHNOLOGIES LTD -10.0K (-100.0%) -20.3K (-100.0%) 0.00% -0.025 pp 0.00% +0.000 pp USD 2 qtrs SOLD
72 NISA INVESTMENT ADVISORS, LLC -291.0 (-100.0%) -588.0 (-100.0%) 0.00% -0.001 pp 0.00% +0.000 pp USD 11 qtrs SOLD
73 IFP ADVISORS, INC -54.0 (-100.0%) -109.0 (-100.0%) 0.00% 0.000 pp 0.00% +0.000 pp USD 9 qtrs SOLD
74 ROYAL BANK OF CANADA -2.5K (-100.0%) -5.0K (-100.0%) 0.00% -0.006 pp 0.00% +0.000 pp USD 19 qtrs SOLD
75 GF FUND MANAGEMENT CO. LTD. -1.3K (-100.0%) -2.6K (-100.0%) 0.00% -0.003 pp 0.00% +0.000 pp USD 5 qtrs SOLD
76 SCIENTECH RESEARCH LLC -12.2K (-100.0%) -24.7K (-100.0%) 0.00% -0.030 pp 0.00% -0.009 pp USD 2 qtrs SOLD
77 CWM, LLC -364.0 (-100.0%) -1.0K (-100.0%) 0.00% -0.001 pp 0.00% +0.000 pp USD 6 qtrs SOLD
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 12 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 iShares Micro-Cap ETF IWC 0.02% 304.9K 0.60%
2 Vanguard Extended Market ETF VXF 0.00% 855.4K 0.05%
3 Vanguard U.S. Total Market Shares Index ETF VTS.AX 0.00% 6.2K 0.03%
4 Vanguard U.S. Total Market Index ETF VUN.TO 0.00% 17.0K 0.17%
5 Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO 0.00% 1.3K 0.17%
6 Vanguard Total Stock Market ETF VTI 0.00% 2.91M 0.03%
7 Vanguard All-Equity ETF Portfolio VEQT.TO 0.00% 6.4K 0.22%
8 Vanguard Growth ETF Portfolio VGRO.TO 0.00% 3.5K 0.22%
9 Vanguard Balanced ETF Portfolio VBAL.TO 0.00% 1.4K 0.22%
10 Vanguard Conservative ETF Portfolio VCNS.TO 0.00% 154.69 0.22%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
2
Sells
0
Shares acquired
1.12M
Shares disposed
Cash buys
Cash sales
Net activity
+1,119,989
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-01 Hitchcock Michael J.M. Director / Officer A-Award A Stock Option (Right to Buy) 667,477 1.49 994.5K 667,477 D
2026-04-01 Erdtmann Rainer M Director / Officer A-Award A Stock Option (Right to Buy) 452,512 1.49 674.2K 452,512 D
2025-12-31 Erdtmann Rainer M Director / Officer Common Stock 0 0.00 1,134,989 I
2025-12-11 Erdtmann Rainer M Director / Officer P-Purchase A Common Stock 30,000 1.43 43.0K 723,027 D
2025-12-02 Hitchcock Michael J.M. Director / Officer P-Purchase A Common Stock 100,000 0.99 99.2K 115,000 D
2025-12-01 Erdtmann Rainer M Director / Officer P-Purchase A Common Stock 10,000 1.05 10.5K 693,027 D
2025-11-28 Erdtmann Rainer M Director / Officer P-Purchase A Common Stock 40,000 1.10 44.1K 683,027 D
2025-08-11 Hitchcock Michael J.M. Director / Officer A-Award A Stock Option (Right to Buy) 916,434 1.53 1.40M 916,434 D
2025-08-11 Erdtmann Rainer M Director / Officer A-Award A Stock Option (Right to Buy) 1,246,989 1.53 1.91M 1,246,989 D
2025-08-01 Chen Bihua 0 0.00 0
2025-07-22 Averill Julianne Director A-Award A Stock Option (Right to Buy) 241,177 1.82 438.9K 241,177 D
2025-06-11 Ray Sumita Director A-Award A Stock Option (Right to Buy) 91,970 2.50 229.9K 91,970 D
2025-06-11 Faust Elizabeth Director A-Award A Stock Option (Right to Buy) 91,970 2.50 229.9K 91,970 D
2025-06-11 Chen Bihua Director / 10% Owner A-Award A Stock Option (Right to Buy) 91,970 2.50 229.9K 91,970 D
2025-06-11 AGUIAR ERIC Director A-Award A Stock Option (Right to Buy) 91,970 2.50 229.9K 91,970 D
2025-03-26 Hitchcock Michael J.M. Director / Officer A-Award A Stock Option (Right to Buy) 350,000 2.52 882.0K 350,000 D
2025-01-31 Erdtmann Rainer M Director / Officer G-Gift A Common Stock 10,000 0.00 20,000 I
2025-01-28 Erdtmann Rainer M Director / Officer G-Gift D Common Stock 40,000 0.00 673,027 D
2024-11-30 Valle Franco Officer A-Award A Common Stock 495 6.15 3.0K 42,995 D
2024-09-30 Hitchcock Michael J.M. Director P-Purchase A Common Stock 10,000 10.06 100.6K 15,000 D
2024-06-12 Ray Sumita Director A-Award A Stock Option (Right to Buy) 51,025 4.63 236.2K 51,025
2024-06-12 Hitchcock Michael J.M. Director A-Award A Stock Option (Right to Buy) 51,025 4.63 236.2K 51,025
2024-06-12 Faust Elizabeth Director A-Award A Stock Option (Right to Buy) 51,025 4.63 236.2K 51,025
2024-06-12 Chen Bihua Director / 10% Owner A-Award A Stock Option (right to buy) 51,025 4.63 236.2K 51
2024-06-12 AGUIAR ERIC Director A-Award A Stock Option (Right to Buy) 51,025 4.63 236.2K 51,025
2024-06-11 Valle Franco Officer P-Purchase A Common Stock 12,509 4.43 55.4K 42,500
2024-05-31 Valle Franco Officer A-Award A Common Stock 4,448 3.78 16.8K 29,991
2024-05-31 Frias Juan Pablo Officer A-Award A Common Stock 349 8.94 3.1K 349
2024-01-17 Valle Franco Officer A-Award A Stock Option (Right to Buy) 145,245 14.44 2.10M 145,245
2024-01-17 Frias Juan Pablo Officer A-Award A Stock Option (Right to Buy) 111,090 14.44 1.60M 111,090
2024-01-17 Erdtmann Rainer M Director / Officer A-Award A Stock Option (Right to Buy) 135,700 14.44 1.96M 135,700
2024-01-17 Butler Thomas Andrew Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 407,502 14.44 5.88M 407,502
2023-12-29 Erdtmann Rainer M Director / Officer G-Gift D Common Stock 3,000 0.00 725,027
2023-11-30 Valle Franco Officer A-Award A Common Stock 1,345 3.78 5.1K 25,543
2023-08-31 Frias Juan Pablo Officer A-Award A Stock Option (Right to Buy) 300,000 16.87 5.06M 300,000
2023-06-14 Ray Sumita Director A-Award A Stock Option (Right to Buy) 6,989 38.90 271.9K 6,989
2023-06-14 Hitchcock Michael J.M. Director A-Award A Stock Option (Right to Buy) 6,989 38.90 271.9K 6,989
2023-06-14 Faust Elizabeth Director A-Award A Stock Option (Right to Buy) 6,989 38.90 271.9K 6,989
2023-06-14 Chen Bihua Director / 10% Owner A-Award A Stock Option (right to buy) 6,989 38.90 271.9K 6,989
2023-06-14 AGUIAR ERIC Director A-Award A Stock Option (Right to Buy) 6,989 38.90 271.9K 6,989
2023-06-01 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 50,000 34.56 1.73M 3,500,000
2023-05-31 Valle Franco Officer A-Award A Common Stock 4,273 3.78 16.2K 24,198
2023-05-31 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 75,000 33.81 2.54M 3,550,000
2023-05-12 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 25,000 33.84 846.0K 3,625,000
2023-05-09 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 150,000 34.50 5.18M 3,650,000
2023-05-08 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 100,000 33.99 3.40M 3,800,000
2023-04-20 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 200,000 29.12 5.82M 3,900,000
2023-03-31 A2A Pharmaceuticals, Inc. 10% Owner S-Sale D Common Stock 200,000 31.25 6.25M 4,100,000
2023-03-30 Chen Bihua Director / 10% Owner P-Purchase A Common Stock 400,000 30.00 12.00M 3,570,872
2023-01-06 Valle Franco Officer A-Award A Stock Option (Right to Buy) 126,300 0.00 126,300
2023-01-06 Erdtmann Rainer M Officer A-Award A Stock Option (Right to Buy) 118,000 0.00 118,000
2023-01-06 Butler Thomas Andrew Officer A-Award A Stock Option (Right to Buy) 354,350 0.00 354,350
2022-12-31 Erdtmann Rainer M Director / Officer I Common Stock 0 0.00 174,614
2022-11-30 Valle Franco Officer A-Award A Common Stock 2,518 3.78 9.5K 19,925
2022-11-14 Hitchcock Michael J.M. Director P-Purchase A Common Stock 5,000 7.93 39.7K 5,000
2022-11-11 Valle Franco Officer P-Purchase A Common Stock 4,100 7.63 31.3K 17,407
2022-08-16 A2A Pharmaceuticals, Inc. Director P-Purchase D Common Stock 30,684 13.87 425.6K 4,300,000
2022-07-21 A2A Pharmaceuticals, Inc. Director S-Sale D Common Stock 34,658 11.21 388.5K 4,330,684
2022-06-24 A2A Pharmaceuticals, Inc. Director S-Sale D Common Stock 34,658 11.76 407.6K 4,365,342
2022-06-22 Ray Sumita Director A-Award A Stock Option (Right to Buy) 23,867 10.20 243.4K 23,867
2022-06-22 Hitchcock Michael J.M. Director A-Award A Stock Option (Right to Buy) 23,867 0.00 23,867
2022-06-22 Faust Elizabeth Director 0 0.00 0
2022-06-22 Cormorant Asset Management, LP Director A-Award A Stock Option (right to buy) 23,867 0.00 23,867
2022-06-22 Chen Bihua Director / 10% Owner A-Award A Stock Option (right to buy) 23,867 10.20 243.4K 23,867
2022-06-22 AGUIAR ERIC Director A-Award A Stock Option (Right to Buy) 23,867 10.20 243.4K 23,867
2022-06-01 Biomea Health, LLC Director J-Other D Common Stock 4,365,342 0.00 0
2022-05-31 Valle Franco Officer A-Award A Common Stock 3,307 4.67 15.4K 13,307
2022-03-03 Ray Sumita Director A-Award A Stock Option (Right to Buy) 21,461 0.00 21,461
2022-01-14 Valle Franco Officer P-Purchase A Common Stock 10,000 8.68 86.8K 10,000
2021-12-04 Valle Franco Officer A-Award A Stock Option (Right to Buy) 144,770 9.80 1.42M 144,770
2021-12-04 Erdtmann Rainer M Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 165,490 9.80 1.62M 165,490
2021-12-04 Butler Thomas Andrew Director / Officer / 10% Owner A-Award A Stock Option (Right to Buy) 305,400 9.80 2.99M 305,400
2021-09-17 Stergiopoulos Sotirios Director P-Purchase A Common Stock 34,658 10.96 379.9K 4,400,000
2021-09-17 A2A Pharmaceuticals, Inc. 10% Owner P-Purchase A Common Stock 34,658 10.96 379.9K 4,400,000
2021-08-23 Erdtmann Rainer M Director / Officer / 10% Owner P-Purchase A Common Stock 24,000 13.20 316.9K 228,470
2021-08-23 Butler Thomas Andrew Director / Officer / 10% Owner P-Purchase A Common Stock 24,000 13.20 316.9K 228,470
2021-08-18 Erdtmann Rainer M Director / Officer / 10% Owner P-Purchase A Common Stock 14,000 10.77 150.7K 204,470
2021-08-18 Butler Thomas Andrew Director / Officer / 10% Owner P-Purchase A Common Stock 14,000 10.77 150.7K 204,470
2021-08-17 Erdtmann Rainer M Officer P-Purchase A Common Stock 14,000 10.79 151.1K 190,470
2021-08-17 Butler Thomas Andrew Director / Officer / 10% Owner P-Purchase A Common Stock 14,000 10.79 151.1K 190,470
2021-08-03 Valle Franco Officer A-Award A Stock Option (Right to Buy) 165,000 13.45 2.22M 165,000
2021-07-26 Valle Franco Officer 0 0.00 0
2021-06-16 Ray Sumita Director A-Award A Stock Option (Right to Buy) 17,724 20.46 362.6K 17,724
2021-04-20 Chen Bihua Director P-Purchase A Common Stock 900,000 17.00 15.30M 3,170,872
2021-04-15 Stergiopoulos Sotirios Director A-Award A Stock Option (Right to Buy) 28,911 17.00 491.5K 28,911
2021-04-15 Ryan Sunny Officer D Common Stock 0 0.00 63,114
2021-04-15 Hitchcock Michael J.M. Director 0 0.00 0
2021-04-15 Erdtmann Rainer M Director / Officer / 10% Owner P-Purchase A Common Stock 3,000 17.00 51.0K 3,000
2021-04-15 Cormorant Asset Management, LP Director / 10% Owner A-Award D Stock Option (right to buy) 28,911 17.00 491.5K 28,911
2021-04-15 Chen Bihua Director / 10% Owner I Series A Convertible Preferred Stock 2,270,872 0.00 0
2021-04-15 Butler Thomas Andrew Director / Officer / 10% Owner I Common Stock 0 0.00 2,182,671
2021-04-15 Biomea Health, LLC 10% Owner I Common Stock 0 0.00 4,365,342
2021-04-15 AGUIAR ERIC Director 0 0.00 0
2021-04-15 A2A Pharmaceuticals, Inc. 10% Owner D Common Stock 0 0.00 4,365,342

Executive team

Top executives
Shares Outstanding
59.50M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Michael J.M. Hitchcock, Ph.D. Interim Chief Executive Officer and Principal Executive Officer 486.7K 220.1K 1.85M 14.1K 2.57M 71.94%
2 2025 Rainer (Ramses) Erdtmann Chief Operating Officer, President, Principal Financial Officer and Principal Accounting Officer 489.6K 146.9K 1.57M 2.21M 71.21%
3 2025 Thomas Butler Former Chief Executive Officer and Former Chairman of the Board 148.8K 513.2K 662.0K 0.00%
4 2025 Juan Pablo Frias, M.D. Former Chief Medical Officer 325.0K 158.7K 65.3K 549.0K 28.91%
5 2024 Thomas Butler Former Chief Executive Officer and Former Chairman of the Board 633.6K 4.47M 5.11M 87.59%
6 2024 Franco Valle Former Chief Financial Officer 483.8K 1.59M 2.08M 76.72%
7 2024 Rainer (Ramses) Erdtmann Chief Operating Officer and President 489.6K 1.49M 1.98M 75.26%
8 2024 Rainer (Ramses) Erdtmann Chief Operating Officer, President, Principal Financial Officer and Principal Accounting Officer 489.6K 1.49M 1.98M 75.26%
9 2023 Juan Pablo Frias, M.D. Chief Medical Officer 168.4K 75.5K 3.68M 12.6K 3.93M 93.48%
10 2023 Thomas Butler Former Chief Executive Officer and Former Chairman of the Board 609.2K 341.2K 1.76M 2.71M 64.89%
11 2023 Thomas Butler Chief Executive Officer and Chairman of the Board 609.2K 341.2K 1.76M 2.71M 64.89%
12 2023 Franco Valle Chief Financial Officer 465.2K 208.4K 626.2K 1.30M 48.17%
13 2023 Franco Valle Former Chief Financial Officer 465.2K 208.4K 626.2K 1.30M 48.17%
14 2023 Rainer (Ramses) Erdtmann Chief Operating Officer and President 470.8K 210.9K 585.1K 1.27M 46.19%
15 2022 Thomas Butler Chief Executive Officer and Chairman of the Board 583.0K 338.1K 921.1K 0.00%
16 2022 Rainer (Ramses) Erdtmann Chief Operating Officer and President 450.5K 209.0K 659.5K 0.00%
17 2022 Franco Valle Chief Financial Officer 445.2K 206.6K 651.8K 0.00%
18 2021 Thomas Butler Chief Executive Officer and Chairman of the Board 552.0K 220.8K 5.89M 6.66M 88.40%
19 2021 Thomas Butler Chief Executive Officer and Chairman of the Board 552.0K 220.8K 5.89M 6.66M 88.40%
20 2021 Franco Valle Chief Financial Officer 185.8K 65.9K 2.71M 2.96M 91.49%
21 2021 Rainer (Ramses) Erdtmann Chief Operating Officer and President 429.5K 141.1K 2.33M 2.90M 80.33%
22 2021 Ramses Erdtmann Chief Operating Officer and President 429.5K 141.1K 2.33M 2.90M 80.33%
23 2020 Thomas Butler Chief Executive Officer and Chairman of the Board 228.8K 134.4K 1.15M 1.52M 76.05%
24 2020 Ramses Erdtmann Chief Operating Officer and President 14.8K 21.4K 270.7K 306.9K 88.21%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-27 DEF 14A
2025-04-28 DEF 14A
2025-04-18 PRE 14A
2024-04-26 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-11 8-K
2026-05-11 10-Q
2026-04-28 8-K
2026-04-27 DEF 14A
2026-04-27 ARS
2026-04-03 4
2026-04-03 4
2026-03-24 8-K
2026-03-24 10-K
2026-02-25 8-K

Executive team

NameTitleCompensationGender
Michael J. Hitchcock Interim Chief Executive Officer & Director 867.9K
Ramses Erdtmann Co-Founder, President, Chief Operating Officer & Director 636.5K male
Heow Tan Chief Technology & Quality Officer male
Caroline Perez- Dupont Senior Vice President of Contracts
Ravi Upasani Executive Vice President of Intellectual Property male
Stephan Morris Chief Development Officer
Thorsten Kirschberg Executive Vice President of Research
ESG Rating
B
BIOTECHNOLOGY
Rank: 442 out of 710
2026
E (Environmental)
56.2 / 56.3
Company / Sector avg.
S (Social)
61.6 / 62.4
Company / Sector avg.
G (Governance)
62.9 / 60.9
Company / Sector avg.
ESG Total
60.2 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

Share your view on this stock and instantly see how the community has voted over the last 6 months.

These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

Dividend history

Earnings history

Earnings reports

Stock splits