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Axsome Therapeutics, Inc. (AXSM)

USD229.57 +1.29 (+0.56%)
US NASDAQ Healthcare Biotechnology
Address 22 Cortlandt Street 10007
New York City, NY, US
CEO Herriot Tabuteau
Website axsome.com
IPO 2015-11-19
CIK 1579428 ISIN US05464T1043

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Also trades on London Stock Exchange · 0HKF.L (USD) NASDAQ Global Market · AXSM (USD)
Description

Axsome Therapeutics, Inc. is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for a range of central nervous system (CNS) disorders within the United States. Its robust product pipeline features several promising candidates, including: AXS-05, an investigational therapy currently being developed for major depressive disorder and treatment-resistant depression. This compound is also in Phase III clinical evaluation for Alzheimer's disease agitation and has successfully finished Phase II trials investigating its use for smoking cessation. AXS-07, a novel, orally administered, rapidly-acting investigational medicine that employs multiple mechanisms of action. It has concluded two Phase III studies for the acute treatment of migraine attacks. AXS-12, a selective and potent norepinephrine reuptake inhibitor, which is presently undergoing a Phase III trial for narcolepsy. AXS-14, an oral investigational drug, advancing through Phase III trials for the management of fibromyalgia. Axsome Therapeutics also engages in a research collaboration with Duke University to further assess AXS-05's potential in smoking cessation. The company, established in 2012, has its main offices in New York, New York.

News Sentiment (7d)
Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD229.57 +1.29 (+0.56%)
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Volume Profile
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Liquidity & share structure
Average Volume
902.8K
Beta
0.60
Float Shares
43.24M
Free Float %
84.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+3.49% +1.57% +25.63% +23.63% +63.05% +22.66% +112.01% +188.07% +273.20% +2,003.57% +2,463.27%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (25 ratings, all time) Buy
Price Targets & DCF
Current price
229.57
Low 200.00 -12.9%
Consensus 255.81 +11.4%
Median 259.50 +13.0%
High 302.00 +31.6%
Ratings Trend (MoM) 95% Bullish
Rating 2026-05 Change
Strong Buy 3 0
Buy 17 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 15
266.00
+15.9%
Last Quarter 25
249.04
+8.5%
Last Year 43
231.21
+0.7%
All Time 70
186.84
-18.6%
Quality scores
Altman Z-Score
7.93
Safe zone
Piotroski F-Score
4 / 9
Average
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +65.6% Q1'26: +57.4% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +38.6% Q1'26: -3.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -30.9% Q1'26: -10.9% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -27.7% Q1'26: -33.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -2,661.1% Q1'26: +749.5% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +3.8% Q1'26: +4.8% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -1.44× Q1'26: -0.89× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.59) × ERP
WACC = 98% × Ke + 2% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 229.57
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
17 Rev. Ana.
13 EPS Ana.
Dec 2027
17 Rev. Ana.
13 EPS Ana.
Dec 2028
17 Rev. Ana.
16 EPS Ana.
Dec 2029
14 Rev. Ana.
14 EPS Ana.
Dec 2030
8 Rev. Ana.
14 EPS Ana.
Revenue
50.04M
est: 46.98M (+6.5%)
270.60M
est: 291.49M (-7.2%)
385.69M
est: 385.05M (+0.2%)
638.50M
est: 635.67M (+0.4%)
983.80M
869.18M – 1.12B
+54.8% YoY
1.60B
1.21B – 1.91B
+62.5% YoY
2.28B
2.28B – 2.28B
+42.5% YoY
3.09B
2.60B – 3.69B
+35.6% YoY
3.76B
3.16B – 4.48B
+21.6% YoY
EBITDA
-175.40M
est: -5.06M (-3,368.2%)
-224.99M
est: -105.02M (-114.2%)
-272.60M
est: -138.73M (-96.5%)
-168.08M
est: -229.03M (+26.6%)
-354.46M
-404.27M – -313.17M
-54.8% YoY
-576.06M
-689.01M – -436.75M
-62.5% YoY
-820.67M
-820.67M – -820.67M
-42.5% YoY
-1.11B
-1.33B – -937.72M
-35.6% YoY
-1.35B
-1.62B – -1.14B
-21.6% YoY
EBIT
-179.80M
est: -5.49M (-3,176.0%)
-231.83M
est: -108.53M (-113.6%)
-280.56M
est: -143.36M (-95.7%)
-177.15M
est: -236.67M (+25.2%)
-366.28M
-417.75M – -323.61M
-54.8% YoY
-595.27M
-711.99M – -451.32M
-62.5% YoY
-848.04M
-848.04M – -848.04M
-42.5% YoY
-1.15B
-1.37B – -969.00M
-35.6% YoY
-1.40B
-1.67B – -1.18B
-21.6% YoY
Net Income
-187.13M
est: -207.59M (+9.9%)
-239.24M
est: -308.55M (+22.5%)
-287.22M
est: -246.90M (-16.3%)
-183.17M
est: -188.30M (+2.7%)
-98.44M
-301.94M – -3.19M
+47.7% YoY
326.97M
-494.40M – 734.82M
+432.1% YoY
826.05M
-204.21M – 1.61B
+152.6% YoY
1.22B
972.05M – 1.53B
+47.9% YoY
1.57B
1.25B – 1.96B
+28.2% YoY
SGA
159.25M
est: 69.94M (+127.7%)
323.12M
est: 427.73M (-24.5%)
411.36M
est: 565.03M (-27.2%)
570.60M
est: 932.79M (-38.8%)
1.44B
1.28B – 1.65B
+54.8% YoY
2.35B
1.78B – 2.81B
+62.5% YoY
3.34B
3.34B – 3.34B
+42.5% YoY
4.53B
3.82B – 5.41B
+35.6% YoY
5.51B
4.64B – 6.58B
+21.6% YoY
EPS
-4.60
est: -4.33 (-6.2%)
-5.27
est: -6.51 (+19.1%)
-5.99
est: -5.46 (-9.8%)
-3.68
est: -3.76 (+2.1%)
-1.96
-6.07 – -0.06
+47.8% YoY
5.78
-9.94 – 14.77
+394.6% YoY
14.40
-4.11 – 32.40
+149.2% YoY
24.56
19.54 – 30.76
+70.6% YoY
31.49
25.05 – 39.44
+28.2% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-05 RBC Capital Outperform Outperform Maintain
2026-05-04 HC Wainwright & Co. Buy Buy Maintain
2026-05-01 Needham Buy Buy Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-11 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-05-08 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 2/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 2/5 1/5 1/5 1/5 1/5 1/5
2026-05-01 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5
2026-04-15 C- 1/5 3/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-63.00M
OE per share TTM
-1.25
Owner's Yield
-0.57%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
2.9%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
98
Total invested
433.23M
Insider transactions (90d)
6
Beneficial owners (>5%)
28
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 RTW Investments, LP 2.98M 6.90% 2.98M IA, PN Delaware 2023-02-14
2 Roderick Wong 2.98M 6.90% 2.98M HC, IN United States 2023-02-14
3 Abigail P. Johnson 2.87M 15.00% 2.87M IN Delaware 2015-12-10
4 Edward C. Johnson 3d 2.87M 15.00% 2.87M IN Delaware 2015-12-10
5 FMR LLC 2.87M 15.00% 2.87M HC Delaware 2015-12-10
6 The Vanguard Group - 23-1945930 2.64M 7.07% 63.9K 86.1K IA Pennsylvania 2021-02-10
7 Fairmount Funds Management LLC 2.34M 5.00% 2.34M IA Delaware 2023-07-07
8 Peter Harwin 2.34M 5.00% 2.34M HC, IN United States 2023-07-07
9 Tomas Kiselak 2.34M 5.00% 2.34M HC, IN Slovak Republic 2023-07-07
10 Fairmount Healthcare Fund II L.P. 2.28M 4.90% 2.28M PN Delaware 2023-07-07
11 (1) BlackRock, Inc. 2.11M 5.60% 2.08M 2.11M HC Delaware 2022-02-03
12 David L. Cohen 2.06M 5.50% 2.06M IN Delaware 2021-02-04
13 Harold J. Levy 2.06M 5.50% 2.06M IN Delaware 2021-02-04
14 Iridian Asset Management LLC 2.06M 5.50% 2.06M IA Delaware 2021-02-04
15 Select Biotechnology Portfolio 1.91M 10.00% 1.91M IV Delaware 2015-12-10
16 Koh, Bong 1.64M 5.00% 1.64M IN Delaware 2019-01-28
17 Shah, Nimish 1.64M 5.00% 1.64M IN Delaware 2019-01-28
18 VHCP Co-Investment Holdings II, LLC 1.64M 5.00% 1.64M OO Delaware 2019-01-28
19 VHCP Co-Investment Holdings III, LLC 1.64M 5.00% 1.64M OO Delaware 2019-01-28
20 VHCP Management II, LLC 1.64M 5.00% 1.64M OO Delaware 2019-01-28
21 VHCP Management III, LLC 1.64M 5.00% 1.64M OO Delaware 2019-01-28
22 Venrock Healthcare Capital Partners II, L.P. 1.64M 5.00% 1.64M PN Delaware 2019-01-28
23 Venrock Healthcare Capital Partners III, L.P. 1.64M 5.00% 1.64M PN Delaware 2019-01-28
24 JPMorgan Chase & Co. 1.59M 8.20% 1.58M HC Delaware 2017-01-13
25 Laurence W.Lytton 1.30M 5.50% 1.27M 31.4K 1.27M 31.4K IN USA 2017-04-27
26 Fidelity Advisor Biotechnology Fund 956.9K 5.00% 956.9K IV Delaware 2015-12-10
27 Fairmount Healthcare Fund L.P. 66.8K 0.10% 66.8K PN Delaware 2023-07-07
28 PFM Health Sciences, LP 6.00 5.40% 2.16M 2.16M IA, PN, IN Delaware 2022-10-24

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
98
-322 vs prev Q
New positions
12
Closed positions
315
Increased
47
Reduced
27
Put/Call ratio
0.00
Calls held
600.00
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 MACQUARIE MANAGEMENT HOLDINGS, INC. 989.4K +989.4K (+100.0%) 180.71B +180.7B (+100.0%) 1.98% +1.978 pp 0.27% +0.273 pp USD182.64 +0.0% 1 qtrs NEW
2 VANGUARD GROUP INC 4.16M -15.8K (-0.4%) 760.66M +252.9M (+49.8%) 8.33% -0.130 pp 0.01% +0.003 pp USD58.73 +211.0% 40 qtrs
3 BLACKROCK, INC. 3.91M +122.6K (+3.2%) 714.77M +254.4M (+55.2%) 7.82% +0.156 pp 0.01% +0.004 pp USD93.74 +94.8% 6 qtrs
4 PRICE T ROWE ASSOCIATES INC /MD/ 1.51M +472.4K (+45.5%) 275.76M +149.8M (+118.9%) 3.02% +0.920 pp 0.03% +0.016 pp USD133.15 +37.2% 27 qtrs
5 INVESCO LTD. 1.27M +282.9K (+28.6%) 232.59M +112.3M (+93.3%) 2.55% +0.542 pp 0.04% +0.017 pp USD119.52 +52.8% 28 qtrs
6 WELLINGTON MANAGEMENT GROUP LLP 1.22M -112.9K (-8.5%) 223.12M +61.0M (+37.7%) 2.44% -0.257 pp 0.04% +0.011 pp USD97.99 +86.4% 11 qtrs
7 FMR LLC 1.18M +253.7K (+27.3%) 215.81M +103.1M (+91.5%) 2.36% +0.486 pp 0.01% +0.005 pp USD102.51 +78.2% 26 qtrs
8 DEEP TRACK CAPITAL, LP 1.15M +250.0K (+27.8%) 210.04M +100.7M (+92.2%) 2.30% +0.479 pp 3.74% +0.694 pp USD122.86 +48.7% 3 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 1.01M +12.5K (+1.3%) 184.54M +63.4M (+52.3%) 2.02% +0.002 pp 0.01% +0.004 pp USD56.92 +220.9% 40 qtrs
10 STATE STREET CORP 958.2K +15.2K (+1.6%) 175.00M +60.5M (+52.8%) 1.92% +0.008 pp 0.01% +0.002 pp USD49.82 +266.6% 28 qtrs
11 RTW INVESTMENTS, LP 888.0K -230.9K (-20.6%) 162.18M +26.3M (+19.4%) 1.78% -0.488 pp 1.62% -0.050 pp USD62.79 +190.9% 28 qtrs
12 ALETHEA CAPITAL MANAGEMENT, LLC 668.7K -2.2K (-0.3%) 122.13M +40.7M (+49.9%) 1.34% -0.020 pp 59.30% +6.958 pp USD12.65 +1,343.8% 33 qtrs
13 BANK OF AMERICA CORP /DE/ 618.0K +256.8K (+71.1%) 112.88M +69.0M (+157.3%) 1.24% +0.505 pp 0.01% +0.005 pp USD136.09 +34.2% 29 qtrs
14 EVENTIDE ASSET MANAGEMENT, LLC 571.2K -175.2K (-23.5%) 104.20M +13.6M (+15.0%) 1.14% -0.368 pp 1.63% +0.137 pp USD78.16 +133.7% 10 qtrs
15 D. E. SHAW & CO., INC. 549.1K +252.8K (+85.3%) 100.29M +64.3M (+178.7%) 1.10% +0.499 pp 0.06% +0.035 pp USD147.42 +23.9% 9 qtrs
16 NORGES BANK 495.5K +495.5K (+100.0%) 90.49M +90.5M (+100.0%) 0.99% +0.991 pp 0.01% +0.010 pp USD182.64 +0.0% 1 qtrs NEW
17 MORGAN STANLEY 491.2K +81.6K (+19.9%) 89.71M +40.0M (+80.4%) 0.98% +0.154 pp 0.01% +0.002 pp USD93.90 +94.5% 41 qtrs
18 ASSENAGON ASSET MANAGEMENT S.A. 468.0K +173.2K (+58.8%) 85.47M +49.7M (+138.7%) 0.94% +0.339 pp 0.12% +0.069 pp USD142.15 +28.5% 7 qtrs
19 PICTET ASSET MANAGEMENT HOLDING SA 436.1K +73.9K (+20.4%) 79.64M +35.7M (+81.1%) 0.87% +0.139 pp 0.08% +0.035 pp USD125.47 +45.6% 10 qtrs
20 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 402.7K +20.7K (+5.4%) 73.55M +27.1M (+58.5%) 0.81% +0.032 pp 0.01% +0.004 pp USD63.66 +186.9% 27 qtrs
21 NORTHERN TRUST CORP 390.4K -19.1K (-4.7%) 71.31M +21.6M (+43.4%) 0.78% -0.048 pp 0.01% +0.003 pp USD45.98 +297.2% 39 qtrs
22 ADAGE CAPITAL PARTNERS GP, L.L.C. 367.6K -77.4K (-17.4%) 67.13M +13.1M (+24.2%) 0.73% -0.165 pp 0.10% +0.016 pp USD101.35 +80.2% 16 qtrs
23 HOOD RIVER CAPITAL MANAGEMENT LLC 366.2K +6.2K (+1.7%) 66.88M +23.2M (+53.0%) 0.73% +0.004 pp 0.73% +0.217 pp USD105.72 +72.8% 13 qtrs
24 PRINCIPAL FINANCIAL GROUP INC 363.1K -5.3K (-1.4%) 66.32M +21.6M (+48.2%) 0.73% -0.019 pp 0.03% +0.011 pp USD96.65 +89.0% 25 qtrs
25 UBS GROUP AG 355.3K +142.9K (+67.2%) 64.90M +39.1M (+151.5%) 0.71% +0.281 pp 0.01% +0.007 pp USD134.02 +36.3% 28 qtrs
26 NUVEEN, LLC 349.2K +50.9K (+17.1%) 63.78M +27.5M (+76.0%) 0.70% +0.095 pp 0.02% +0.007 pp USD126.46 +44.4% 4 qtrs
27 FRANKLIN RESOURCES INC 342.6K +57.0K (+19.9%) 62.57M +27.9M (+80.4%) 0.68% +0.107 pp 0.02% +0.007 pp USD107.16 +70.4% 13 qtrs
28 QUBE RESEARCH & TECHNOLOGIES LTD 325.4K -186.0 (-0.1%) 59.44M +19.9M (+50.3%) 0.65% -0.008 pp 0.06% +0.020 pp USD100.88 +81.0% 8 qtrs
29 MARSHALL WACE, LLP 320.6K -57.5K (-15.2%) 58.55M +12.6M (+27.5%) 0.64% -0.124 pp 0.05% +0.007 pp USD115.92 +57.6% 5 qtrs
30 LOOMIS SAYLES & CO L P 315.4K -14.7K (-4.5%) 57.60M +17.5M (+43.7%) 0.63% -0.037 pp 0.07% +0.022 pp USD85.15 +114.5% 8 qtrs
31 SUSQUEHANNA INTERNATIONAL GROUP, LLP 311.9K +26.9K (+9.4%) 56.97M +22.4M (+64.6%) 0.62% +0.047 pp 0.01% +0.003 pp USD84.28 +116.7% 33 qtrs
32 BNP PARIBAS ARBITRAGE, SNC 304.4K +114.3K (+60.1%) 55.59M +32.5M (+140.8%) 0.61% +0.224 pp 0.03% +0.013 pp USD121.90 +49.8% 39 qtrs
33 GOLDMAN SACHS GROUP INC 300.9K +76.8K (+34.2%) 54.96M +27.7M (+101.9%) 0.60% +0.148 pp 0.01% +0.003 pp USD106.38 +71.7% 28 qtrs
34 NATIONALE-NEDERLANDEN POWSZECHNE TOWARZYSTWO EMERYTALNE S.A. 278.8K -47.5K (-14.6%) 50.93M +11.3M (+28.5%) 0.56% -0.103 pp 4.52% +1.457 pp USD111.79 +63.4% 5 qtrs
35 BANK OF NEW YORK MELLON CORP 255.1K +1.8K (+0.7%) 46.59M +15.8M (+51.5%) 0.51% -0.002 pp 0.01% +0.002 pp USD75.46 +142.0% 29 qtrs
36 ORBIMED ADVISORS LLC 253.1K -278.7K (-52.4%) 46.23M -18.4M (-28.4%) 0.51% -0.570 pp 0.95% -0.575 pp USD116.62 +56.6% 4 qtrs
37 PFM HEALTH SCIENCES, LP 251.6K -278.8K (-52.6%) 45.95M -18.5M (-28.7%) 0.50% -0.570 pp 4.58% -0.372 pp USD59.23 +208.4% 15 qtrs
38 JPMORGAN CHASE & CO 233.2K -17.3K (-6.9%) 42.59M +12.2M (+40.0%) 0.47% -0.041 pp 0.00% +0.001 pp USD82.48 +121.4% 27 qtrs
39 MAN GROUP PLC 228.6K -59.3K (-20.6%) 41.76M +6.8M (+19.4%) 0.46% -0.125 pp 0.07% +0.010 pp USD106.39 +71.7% 5 qtrs
40 DRIEHAUS CAPITAL MANAGEMENT LLC 220.5K -2.9K (-1.3%) 40.28M +13.1M (+48.4%) 0.44% -0.011 pp 0.27% +0.079 pp USD116.13 +57.3% 4 qtrs
41 VESTAL POINT CAPITAL, LP 210.0K +60.0K (+40.0%) 38.35M +20.1M (+110.5%) 0.42% +0.116 pp 1.30% +0.481 pp USD138.93 +31.5% 2 qtrs
42 FIRST TURN MANAGEMENT, LLC 206.9K +54.3K (+35.6%) 37.79M +19.3M (+103.9%) 0.41% +0.105 pp 4.32% +1.535 pp USD111.24 +64.2% 9 qtrs
43 CITIGROUP INC 204.1K +62.1K (+43.7%) 37.28M +20.0M (+116.1%) 0.41% +0.121 pp 0.02% +0.009 pp USD127.55 +43.2% 28 qtrs
44 TRI LOCUM PARTNERS LP 201.6K -90.5K (-31.0%) 36.83M +1.3M (+3.8%) 0.40% -0.188 pp 4.78% -3.374 pp USD104.70 +74.4% 13 qtrs
45 TWO SIGMA ADVISERS, LP 188.5K +188.5K (+100.0%) 34.43M +34.4M (+100.0%) 0.38% +0.377 pp 0.07% +0.067 pp USD182.64 +0.0% 1 qtrs NEW
46 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 188.3K -20.8K (-10.0%) 34.38M +9.0M (+35.4%) 0.38% -0.047 pp 0.09% +0.010 pp USD103.50 +76.5% 5 qtrs
47 CITADEL ADVISORS LLC 176.0K +85.3K (+94.0%) 32.14M +21.1M (+191.8%) 0.35% +0.168 pp 0.00% +0.003 pp USD128.29 +42.4% 28 qtrs
48 VOYA INVESTMENT MANAGEMENT LLC 173.3K +59.3K (+52.0%) 31.65M +17.8M (+128.5%) 0.35% +0.116 pp 0.03% +0.017 pp USD119.81 +52.4% 27 qtrs
49 RENAISSANCE TECHNOLOGIES LLC 170.0K +20.0K (+13.3%) 31.05M +12.8M (+70.4%) 0.34% +0.037 pp 0.05% +0.024 pp USD124.41 +46.8% 4 qtrs
50 METLIFE INVESTMENT MANAGEMENT, LLC 164.9K -32.4K (-16.4%) 30.11M +6.1M (+25.7%) 0.33% -0.070 pp 0.15% +0.031 pp USD108.77 +67.9% 27 qtrs
51 FRONTIER CAPITAL MANAGEMENT CO LLC 157.7K +31.3K (+24.8%) 28.80M +13.5M (+87.6%) 0.32% +0.060 pp 0.31% +0.168 pp USD125.40 +45.6% 13 qtrs
52 SQUAREPOINT OPS LLC 155.0K +— (+0.0%) 28.31M +9.5M (+50.4%) 0.31% -0.004 pp 0.03% +0.011 pp USD97.46 +87.4% 5 qtrs
53 WOODLINE PARTNERS LP 150.9K -181.0K (-54.5%) 27.55M -12.8M (-31.6%) 0.30% -0.370 pp 0.11% -0.083 pp USD76.59 +138.5% 13 qtrs
54 ALGERT GLOBAL LLC 149.4K +105.2K (+238.4%) 27.29M +21.9M (+408.9%) 0.30% +0.209 pp 0.43% +0.336 pp USD162.41 +12.5% 4 qtrs
55 PERCEPTIVE ADVISORS LLC 148.9K +— (+0.0%) 27.20M +9.1M (+50.4%) 0.30% -0.004 pp 0.48% -0.038 pp USD81.55 +124.0% 11 qtrs
56 TWO SIGMA INVESTMENTS, LP 145.6K +137.4K (+1,674.1%) 26.59M +25.6M (+2,567.9%) 0.29% +0.275 pp 0.04% +0.036 pp USD179.19 +1.9% 4 qtrs
57 RAYMOND JAMES FINANCIAL INC 150.1K -8.6K (-5.4%) 24.78M +5.5M (+28.6%) 0.30% -0.021 pp 0.01% +0.002 pp USD85.39 +113.9% 5 qtrs
58 US BANCORP \DE\ 131.0K -548.0 (-0.4%) 23.92M +7.9M (+49.8%) 0.26% -0.004 pp 0.03% +0.009 pp USD41.63 +338.7% 27 qtrs
59 MANUFACTURERS LIFE INSURANCE COMPANY, THE 133.9K +1.2K (+0.9%) 23.66M +7.5M (+46.8%) 0.27% -0.001 pp 0.02% +0.006 pp USD97.68 +87.0% 27 qtrs
60 CAPTION MANAGEMENT, LLC 125.0K +100.0K (+400.0%) 22.83M +19.8M (+651.9%) 0.25% +0.199 pp 0.16% +0.133 pp USD163.32 +11.8% 17 qtrs
61 RHENMAN & PARTNERS ASSET MANAGEMENT AB 114.8K -58.0K (-33.6%) 20.97M -19.5K (-0.1%) 0.23% -0.120 pp 1.96% -0.363 pp USD97.15 +88.0% 12 qtrs
62 VOLEON CAPITAL MANAGEMENT LP 110.2K +93.4K (+558.4%) 20.12M +18.1M (+890.1%) 0.22% +0.186 pp 0.43% +0.383 pp USD173.35 +5.4% 2 qtrs
63 EMERALD ADVISERS, LLC 108.1K -860.0 (-0.8%) 19.74M +6.5M (+49.2%) 0.22% -0.004 pp 0.61% +0.184 pp USD104.39 +75.0% 3 qtrs
64 AQR CAPITAL MANAGEMENT LLC 103.4K -15.2K (-12.8%) 18.89M +4.5M (+31.1%) 0.21% -0.033 pp 0.01% +0.001 pp USD99.41 +83.7% 15 qtrs
65 CANADA PENSION PLAN INVESTMENT BOARD 103.2K +38.8K (+60.2%) 18.85M +11.0M (+141.0%) 0.21% +0.076 pp 0.01% +0.007 pp USD137.38 +32.9% 5 qtrs
66 DNB ASSET MANAGEMENT AS 101.1K -879.0 (-0.9%) 18.47M +6.1M (+49.1%) 0.20% -0.004 pp 0.06% +0.018 pp USD96.37 +89.5% 8 qtrs
67 AMERIPRISE FINANCIAL INC 99.9K -8.3K (-7.7%) 18.25M +5.1M (+38.8%) 0.20% -0.019 pp 0.00% +0.001 pp USD107.87 +69.3% 14 qtrs
68 DEUTSCHE BANK AG\ 98.3K +1.6K (+1.6%) 17.95M +6.2M (+52.8%) 0.20% +0.001 pp 0.01% +0.002 pp USD76.39 +139.1% 27 qtrs
69 ABRDN PLC 97.4K +2.8K (+2.9%) 17.79M +6.3M (+54.8%) 0.19% +0.003 pp 0.03% +0.009 pp USD95.49 +91.3% 7 qtrs
70 ROYCE & ASSOCIATES LP 94.0K +38.0K (+67.8%) 17.17M +10.4M (+152.3%) 0.19% +0.075 pp 0.17% +0.106 pp USD135.71 +34.6% 8 qtrs
71 NICHOLAS INVESTMENT PARTNERS, LP 91.6K +42.9K (+88.2%) 16.72M +10.8M (+183.0%) 0.18% +0.085 pp 1.22% +0.766 pp USD145.04 +25.9% 13 qtrs
72 WCM INVESTMENT MANAGEMENT, LLC 112.1K -7.6K (-6.4%) 16.67M +2.6M (+18.4%) 0.22% -0.018 pp 0.03% +0.005 pp USD62.12 +194.0% 24 qtrs
73 M&G PLC 90.3K +90.3K (+100.0%) 16.53M +16.5M (+100.0%) 0.18% +0.181 pp 0.08% +0.085 pp USD182.64 +0.0% 1 qtrs NEW
74 WELLS FARGO & COMPANY/MN 89.7K +34.4K (+62.2%) 16.38M +9.7M (+143.9%) 0.18% +0.067 pp 0.00% +0.002 pp USD122.09 +49.6% 40 qtrs
75 FEDERATED HERMES, INC. 87.3K +30.0K (+52.4%) 15.94M +9.0M (+129.1%) 0.17% +0.059 pp 0.03% +0.014 pp USD135.09 +35.2% 4 qtrs
76 UBS ASSET MANAGEMENT AMERICAS INC 87.2K +558.0 (+0.6%) 15.94M +5.4M (+51.4%) 0.17% -0.001 pp 0.00% +0.001 pp USD94.12 +94.1% 27 qtrs
77 GRANITE INVESTMENT PARTNERS, LLC 84.9K -3.7K (-4.1%) 15.51M +4.7M (+44.2%) 0.17% -0.009 pp 0.92% +0.308 pp USD95.47 +91.3% 5 qtrs
78 SPEARS ABACUS ADVISORS LLC 84.2K +3.0 (+0.0%) 15.37M +5.1M (+50.4%) 0.17% -0.002 pp 0.29% +0.095 pp USD78.02 +134.1% 8 qtrs
79 BARCLAYS PLC 76.9K +15.1K (+24.4%) 14.04M +8.5M (+152.8%) 0.15% +0.029 pp 0.00% +0.002 pp USD111.88 +63.2% 11 qtrs
80 CORMORANT ASSET MANAGEMENT, LP 75.0K -25.0K (-25.0%) 13.70M +1.6M (+12.8%) 0.15% -0.052 pp 0.63% -0.205 pp USD81.03 +125.4% 7 qtrs
81 IRIDIAN ASSET MANAGEMENT LLC/CT 73.8K -9.8K (-11.7%) 13.48M +3.3M (+32.8%) 0.15% -0.022 pp 4.96% +0.968 pp USD71.81 +154.3% 28 qtrs
82 SUMMIT FINANCIAL, LLC 70.6K -6.9K (-8.9%) 12.90M +3.5M (+37.0%) 0.14% -0.016 pp 0.19% +0.046 pp USD121.45 +50.4% 2 qtrs
83 NEUBERGER BERMAN GROUP LLC 69.5K -21.7K (-23.8%) 12.69M +1.6M (+14.6%) 0.14% -0.046 pp 0.01% +0.001 pp USD108.23 +68.8% 3 qtrs
84 SWISS NATIONAL BANK 68.9K +2.1K (+3.1%) 12.58M +4.5M (+55.1%) 0.14% +0.003 pp 0.01% +0.003 pp USD57.14 +219.6% 27 qtrs
85 UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH 68.9K +956.0 (+1.4%) 12.58M +4.3M (+52.5%) 0.14% +0.000 pp 0.02% +0.007 pp USD118.33 +54.3% 4 qtrs
86 EMERALD MUTUAL FUND ADVISERS TRUST 67.6K +2.1K (+3.2%) 12.35M +4.4M (+55.2%) 0.14% +0.003 pp 0.60% +0.191 pp USD107.22 +70.3% 3 qtrs
87 AXIOM INVESTORS LLC /DE 63.4K +14.1K (+28.7%) 11.58M +5.6M (+93.5%) 0.13% +0.027 pp 0.10% +0.058 pp USD132.88 +37.4% 4 qtrs
88 IFP ADVISORS, INC 62.4K -865.0 (-1.4%) 11.41M +3.7M (+48.3%) 0.12% -0.003 pp 0.26% +0.056 pp USD88.59 +106.2% 6 qtrs
89 WALLEYE CAPITAL LLC 60.1K +59.6K (+11,920.0%) 10.98M +10.9M (+17,976.0%) 0.12% +0.119 pp 0.03% +0.033 pp USD181.83 +0.4% 8 qtrs
90 PRIVIUM FUND MANAGEMENT B.V. 56.9K +4.1K (+7.9%) 10.39M +4.0M (+62.2%) 0.11% +0.007 pp 1.91% +0.761 pp USD74.02 +146.7% 12 qtrs
91 EDGESTREAM PARTNERS, L.P. 56.4K +38.0K (+207.2%) 10.29M +8.1M (+362.0%) 0.11% +0.076 pp 0.29% +0.225 pp USD161.15 +13.3% 4 qtrs
92 HIGHTOWER ADVISORS, LLC 56.0K -1.1K (-2.0%) 10.22M +3.3M (+47.4%) 0.11% -0.004 pp 0.01% +0.003 pp USD114.42 +59.6% 5 qtrs
93 ATIKA CAPITAL MANAGEMENT LLC 55.5K +6.5K (+13.3%) 10.14M +4.2M (+70.3%) 0.11% +0.012 pp 1.07% +0.588 pp USD107.71 +69.6% 15 qtrs
94 JANE STREET GROUP, LLC 54.8K +1.5K (+2.8%) 10.01M +3.5M (+54.6%) 0.11% +0.002 pp 0.00% +0.001 pp USD110.49 +65.3% 6 qtrs
95 ALLIANCEBERNSTEIN L.P. 53.1K -9.9K (-15.7%) 9.71M +2.0M (+26.7%) 0.11% -0.021 pp 0.00% +0.001 pp USD94.01 +94.3% 27 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
3.00
Bullish
Ratio by volume
3.00
Bullish
Buys
6
Sells
2
Shares acquired
62.9K
Shares disposed
15.0K
Cash buys
Cash sales
1.00
Net activity
+47,886
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-22 Maizel Ari Officer M-Exempt D Stock Option (Right to Buy) 7,500 70.73 530.5K 23,710 D
2026-04-21 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Performance Stock Units 24,081 0.00 24,081 D
2026-04-21 Pizzie Nick Officer A-Award A Performance Stock Units 8,188 0.00 8,188 D
2026-04-21 Murdock Hunter R. Officer A-Award A Performance Stock Units 7,224 0.00 7,224 D
2026-04-21 Maizel Ari Officer A-Award A Performance Stock Units 7,224 0.00 7,224 D
2026-04-21 Jacobson Mark L. Officer A-Award A Performance Stock Units 8,669 0.00 8,669 D
2026-02-26 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Restricted Stock Units 54,623 0.00 54,623 D
2026-02-26 Pizzie Nick Officer A-Award A Restricted Stock Units 18,570 0.00 18,570 D
2026-02-26 Murdock Hunter R. Officer A-Award A Restricted Stock Units 16,385 0.00 16,385 D
2026-02-26 Maizel Ari Officer A-Award A Restricted Stock Units 16,385 0.00 16,385 D
2026-02-26 Jacobson Mark L. Officer A-Award A Restricted Stock Units 19,663 0.00 19,663 D
2026-02-26 Coleman Mark Director S-Sale D Common Stock 25,000 161.11 4.03M 47,140 D
2026-02-23 Coleman Mark Director M-Exempt A Common Stock 6,250 4.95 30.9K 72,140 D
2026-02-20 Coleman Mark Director M-Exempt A Common Stock 12,485 4.95 61.8K 65,890 D
2026-02-10 Coleman Mark Director M-Exempt A Common Stock 5,193 8.02 41.6K 53,405 D
2026-02-02 TABUTEAU HERRIOT Director / Officer / 10% Owner S-Sale D Common Stock 32,410 185.60 6.02M 7,229 D
2026-01-22 Pizzie Nick Officer M-Exempt D Stock Option (Right to Buy) 12,000 3.50 42.0K 105,000 D
2026-01-21 Maizel Ari Officer M-Exempt D Stock Option (Right to Buy) 7,500 70.73 530.5K 31,210 D
2026-01-07 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 31,261 8.02 250.7K 38,490 D
2026-01-06 TABUTEAU HERRIOT Director / Officer / 10% Owner S-Sale D Common Stock 29,450 172.33 5.08M 7,229 D
2026-01-05 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 78,703 8.02 631.2K 85,932 D
2025-12-31 Saad Mark E Director M-Exempt D Stock Option (Right to Buy) 6,231 8.02 50.0K 0 D
2025-12-04 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 10,558 8.02 84.7K 17,787 D
2025-12-03 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 20,163 8.02 161.7K 27,392 D
2025-12-02 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 49,252 8.02 395.0K 56,481 D
2025-11-05 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt D Stock Option (Right to Buy) 21,775 134.49 2.93M 251,797 D
2025-11-04 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt D Stock Option (Right to Buy) 50,459 133.79 6.75M 273,572 D
2025-11-03 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt D Stock Option (Right to Buy) 91,705 132.34 12.14M 324,031 D
2025-10-08 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 12,774 8.02 102.4K 20,003 D
2025-10-07 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 13,390 8.02 107.4K 20,619 D
2025-10-06 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt A Common Stock 19,220 8.02 154.1K 26,449 D
2025-09-22 Jacobson Mark L. Officer M-Exempt D Stock Option (Right to Buy) 10,000 2.85 28.5K 35,378 D
2025-09-16 TABUTEAU HERRIOT Director / Officer / 10% Owner S-Sale D Common Stock 19,719 114.19 2.25M 7,229 D
2025-09-16 Jacobson Mark L. Officer M-Exempt D Stock Option (Right to Buy) 25,000 4.95 123.8K 0 D
2025-09-15 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt D Stock Option (Right to Buy) 15,254 117.37 1.79M 480,839 D
2025-09-12 TABUTEAU HERRIOT Director / Officer / 10% Owner M-Exempt D Stock Option (Right to Buy) 27,907 118.96 3.32M 496,093 D
2025-09-08 Coleman Mark Director P-Purchase A Common Stock 488 127.40 62.2K 48,212 D
2025-09-05 Saad Mark E Director S-Sale D Common Stock 9,127 125.07 1.14M 10,002 D
2025-09-02 JEFFS ROGER Director S-Sale D Common Stock 13,464 123.68 1.67M 57,510 D
2025-08-29 JEFFS ROGER Director S-Sale D Common Stock 20,000 121.27 2.43M 70,974 D
2025-08-28 JEFFS ROGER Director S-Sale D Common Stock 20,000 121.60 2.43M 90,974 D
2025-08-27 JEFFS ROGER Director S-Sale D Common Stock 20,000 122.30 2.45M 110,974 D
2025-08-26 JEFFS ROGER Director S-Sale D Common Stock 20,000 120.03 2.40M 130,974 D
2025-08-22 JEFFS ROGER Director S-Sale D Common Stock 16,694 120.08 2.00M 150,974 D
2025-06-23 Murdock Hunter R. Officer M-Exempt D Stock Option (Right to Buy) 6,014 29.91 179.9K 16,369 D
2025-06-20 Murdock Hunter R. Officer M-Exempt D Stock Option (Right to Buy) 7,500 29.91 224.3K 22,383 D
2025-06-18 Murdock Hunter R. Officer M-Exempt D Stock Option (Right to Buy) 7,500 29.91 224.3K 29,883 D
2025-06-17 Murdock Hunter R. Officer S-Sale D Common Stock 7,500 100.26 752.0K 0 D
2025-06-16 Murdock Hunter R. Officer S-Sale D Common Stock 7,500 102.42 768.2K 0 D
2025-06-09 Jacobson Mark L. Officer M-Exempt A Common Stock 25,000 8.02 200.5K 30,783 D
2025-06-06 Saad Mark E Director A-Award A Restricted Stock Units 1,429 0.00 1,429 D
2025-06-06 Mahony Susan Director A-Award A Restricted Stock Units 1,429 0.00 1,429 D
2025-06-06 JEFFS ROGER Director A-Award A Restricted Stock Units 1,429 0.00 1,429 D
2025-06-06 Coleman Mark Director A-Award A Restricted Stock Units 1,429 0.00 1,429 D
2025-05-28 Jacobson Mark L. Officer M-Exempt A Common Stock 20,000 6.47 129.4K 25,783 D
2025-05-28 Coleman Mark Director S-Sale D Common Stock 3,750 103.43 387.9K 46,637 D
2025-05-27 Jacobson Mark L. Officer S-Sale D Common Stock 20,673 104.66 2.16M 5,783 D
2025-05-27 Coleman Mark Director S-Sale D Common Stock 3,750 105.47 395.5K 50,387 D
2025-05-20 Coleman Mark Director S-Sale D Common Stock 3,000 107.49 322.5K 54,137 D
2025-02-24 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Performance Stock Units 28,609 0.00 28,609 D
2025-02-24 Pizzie Nick Officer A-Award A Performance Stock Units 9,423 0.00 9,423 D
2025-02-24 Murdock Hunter R. Officer A-Award A Performance Stock Units 7,740 0.00 7,740 D
2025-02-24 Maizel Ari Officer A-Award A Performance Stock Units 7,740 0.00 7,740 D
2025-02-24 Jacobson Mark L. Officer A-Award A Performance Stock Units 10,769 0.00 10,769 D
2025-02-21 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Restricted Stock Units 28,609 0.00 28,609 D
2025-02-21 Saad Mark E Director A-Award A Stock Option (Right to Buy) 1,494 137.75 205.8K 1,494 D
2025-02-21 Pizzie Nick Officer A-Award A Employee Stock Option (Right to Buy) 9,516 137.75 1.31M 9,516 D
2025-02-21 Murdock Hunter R. Officer A-Award A Restricted Stock Units 7,740 0.00 7,740 D
2025-02-21 Maizel Ari Officer A-Award A Employee Stock Option (Right to Buy) 7,816 137.75 1.08M 7,816 D
2025-02-21 Mahony Susan Director A-Award A Stock Option (Right to Buy) 1,312 137.75 180.7K 1,312 D
2025-02-21 Jacobson Mark L. Officer A-Award A Employee Stock Option (Right to Buy) 10,875 137.75 1.50M 10,875 D
2025-02-21 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 1,408 137.75 194.0K 1,408 D
2025-02-14 Pizzie Nick Officer M-Exempt A Common Stock 3,000 3.50 10.5K 45,187 D
2025-02-13 Pizzie Nick Officer M-Exempt A Common Stock 12,000 3.50 42.0K 54,187 D
2025-01-03 Coleman Mark Director M-Exempt D Stock Option (Right to Buy) 9,127 9.00 82.1K 0 D
2024-11-19 Coleman Mark Director M-Exempt A Common Stock 33,410 5.94 198.5K 48,010 D
2024-10-14 Maizel Ari Officer Stock Option (Right to Buy) 38,710 70.73 2.74M 0 D
2024-09-11 Saad Mark E Director M-Exempt A Common Stock 11,016 3.67 40.4K 21,018
2024-08-09 Jacobson Mark L. Officer M-Exempt A Common Stock 47,739 4.04 192.9K 53,522
2024-06-07 Saad Mark E Director A-Award A Stock Option (Right to Buy) 5,799 73.90 428.5K 5,799
2024-06-07 Mahony Susan Director A-Award A Stock Option (Right to Buy) 5,799 73.90 428.5K 5,799
2024-06-07 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 5,799 73.90 428.5K 5,799
2024-06-07 Coleman Mark Director A-Award A Stock Option (Right to Buy) 5,799 73.90 428.5K 5,799
2024-05-29 Jacobson Mark L. Officer M-Exempt A Common Stock 13,693 1.30 17.8K 13,693
2024-05-29 Coleman Mark Director S-Sale D Common Stock 5,248 75.14 394.3K 14,600
2024-05-28 Coleman Mark Director S-Sale D Common Stock 5,249 75.21 394.8K 19,848
2024-04-01 Jacobson Mark L. Officer M-Exempt A Common Stock 24,662 1.30 32.1K 24,662
2024-03-15 JEFFS ROGER Director M-Exempt A Common Stock 2,347 29.91 70.2K 123,103
2024-03-14 JEFFS ROGER Director M-Exempt A Common Stock 13,000 22.03 286.4K 133,756
2024-02-27 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Restricted Stock Units 47,886 0.00 47,886
2024-02-27 Saad Mark E Director A-Award A Stock Option (Right to Buy) 1,519 84.00 127.6K 1,519
2024-02-27 Pizzie Nick Officer A-Award A Restricted Stock Units 15,774 0.00 15,774
2024-02-27 Murdock Hunter R. Officer A-Award A Employee Stock Option (Right to Buy) 23,593 84.00 1.98M 23,593
2024-02-27 Mahony Susan Director A-Award A Stock Option (Right to Buy) 191 84.00 16.0K 191
2024-02-27 Jacobson Mark L. Officer A-Award A Employee Stock Option (Right to Buy) 32,825 84.00 2.76M 32,825
2024-02-27 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 1,425 84.00 119.7K 1,425
2023-10-10 Mahony Susan Director A-Award A Stock Option (Right to Buy) 5,873 70.56 414.4K 5,873
2023-09-15 Coleman Mark Director S-Sale D Common Stock 18,572 75.18 1.40M 403,856
2023-06-02 Saad Mark E Director A-Award A Stock Option (Right to Buy) 5,681 74.12 421.1K 5,681
2023-06-02 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 5,681 74.12 421.1K 5,681
2023-06-02 Coleman Mark Director A-Award A Stock Option (Right to Buy) 5,681 74.12 421.1K 5,681
2023-03-02 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Restricted Stock Units 62,400 0.00 62,400
2023-03-02 Saad Mark E Director A-Award A Stock Option (Right to Buy) 2,224 65.32 145.3K 2,224
2023-03-02 Pizzie Nick Officer A-Award A Restricted Stock Units 20,554 0.00 20,554
2023-03-02 Murdock Hunter R. Officer A-Award A Restricted Stock Units 16,883 0.00 16,883
2023-03-02 Jacobson Mark L. Officer A-Award A Employee Stock Option (Right to Buy) 41,424 65.32 2.71M 41,424
2023-03-02 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 2,082 65.32 136.0K 2,082
2023-03-02 Coleman Mark Director A-Award A Stock Option (Right to Buy) 2,870 65.32 187.5K 2,870
2023-01-03 Coleman Mark Director M-Exempt A Common Stock 17,501 1.30 22.8K 25,097
2022-06-13 Murdock Hunter R. Officer D Stock Option (Right to Buy) 52,383 29.91 1.57M 0
2022-06-03 Saad Mark E Director A-Award A Stock Option (Right to Buy) 16,976 25.53 433.4K 16,976
2022-06-03 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 16,976 0.00 16,976
2022-06-03 Coleman Mark Director A-Award A Stock Option (Right to Buy) 16,976 0.00 16,976
2022-03-15 Coleman Mark Director M-Exempt D Stock Option (Right to Buy) 3,496 0.00 17,501
2022-03-04 TABUTEAU HERRIOT Officer A-Award A Restricted Stock Units 110,861 0.00 110,861
2022-03-04 Saad Mark E Director A-Award A Stock Option (Right to Buy) 2,337 0.00 2,337
2022-03-04 Pizzie Nick Officer A-Award A Employee Stock Option (Right to Buy) 77,872 0.00 77,872
2022-03-04 Jacobson Mark L. Officer A-Award A Restricted Stock Units 47,990 0.00 47,990
2022-03-04 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 2,347 0.00 2,347
2022-03-04 Coleman Mark Director A-Award A Stock Option (Right to Buy) 2,798 0.00 2,798
2021-11-19 JEFFS ROGER Director P-Purchase A Common Stock 3,950 37.30 147.4K 120,756
2021-11-18 Pizzie Nick Officer P-Purchase A Common Stock 527 35.50 18.7K 41,789
2021-11-18 Coleman Mark Director P-Purchase A Common Stock 1,021 35.10 35.8K 422,428
2021-11-17 Saad Mark E Director P-Purchase A Common Stock 3,000 34.53 103.6K 10,002
2021-11-12 Pizzie Nick Officer A-Award A Employee Stock Option (Right to Buy) 36,086 39.26 1.42M 36,086
2021-11-12 Jacobson Mark L. Officer A-Award A Employee Stock Option (Right to Buy) 41,638 39.26 1.63M 41,638
2021-06-04 Saad Mark E Director A-Award A Stock Option (Right to Buy) 7,325 61.32 449.2K 7,325
2021-06-04 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 7,325 61.32 449.2K 7,325
2021-06-04 Coleman Mark Director A-Award A Stock Option (Right to Buy) 7,325 61.32 449.2K 7,325
2021-05-12 Coleman Mark Director P-Purchase A Common Stock 500 58.15 29.1K 420,998
2021-03-05 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 97,155 65.02 6.32M 97,155
2021-03-05 Saad Mark E Director A-Award A Stock Option (Right to Buy) 1,241 65.02 80.7K 1,241
2021-03-05 Pizzie Nick Officer A-Award A Employee Stock Option (Right to Buy) 36,086 65.02 2.35M 36,086
2021-03-05 Jacobson Mark L. Officer A-Award A Restricted Stock Units 22,163 0.00 22,163
2021-03-05 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 1,463 65.02 95.1K 1,463
2021-03-05 Coleman Mark Director A-Award A Stock Option (Right to Buy) 1,201 65.02 78.1K 1,201
2020-08-19 Coleman Mark Director G-Gift D Common Stock 397,998 0.00 5,700
2020-06-29 Pizzie Nick Officer P-Purchase A Common Stock 777 76.64 59.5K 41,217
2020-06-29 Coleman Mark Director P-Purchase A Common Stock 650 78.50 51.0K 403,698
2020-06-05 Saad Mark E Director A-Award A Stock Option (Right to Buy) 13,000 77.38 1.01M 13,000
2020-06-05 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 13,000 77.38 1.01M 13,000
2020-06-05 Coleman Mark Director A-Award A Stock Option (Right to Buy) 13,000 77.38 1.01M 13,000
2020-03-17 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 168,776 45.14 7.62M 168,776
2020-03-17 Saad Mark E Director A-Award A Stock Option (Right to Buy) 3,789 45.14 171.0K 3,789
2020-03-17 Pizzie Nick Officer A-Award A Employee Stock Option (Right to Buy) 48,237 45.14 2.18M 48,237
2020-03-17 Marek David C Officer A-Award A Employee Stock Option (Right to Buy) 53,984 45.14 2.44M 53,984
2020-03-17 Jacobson Mark L. Officer A-Award A Employee Stock Option (Right to Buy) 60,880 45.14 2.75M 60,880
2020-03-17 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 4,496 45.14 202.9K 4,496
2020-03-17 Coleman Mark Director A-Award A Stock Option (Right to Buy) 3,308 45.14 149.3K 3,308
2020-02-28 Jacobson Mark L. Officer D Stock Option (Right to Buy) 40,673 6.47 263.2K 0
2020-01-10 JEFFS ROGER Director M-Exempt D Stock Option (Right to Buy) 5,193 8.02 41.6K 0
2019-10-10 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 68,837 17.61 1.21M 68,837
2019-10-10 Pizzie Nick Officer A-Award A Employee Stock Option (right to buy) 25,813 17.61 454.6K 25,813
2019-10-10 Marek David C Officer A-Award A Employee Stock Option (Right to Buy) 25,813 17.61 454.6K 25,813
2019-09-26 Pizzie Nick Officer P-Purchase A Common Stock 2,180 24.80 54.1K 40,440
2019-09-04 Marek David C Officer A-Award A Employee Stock Option (Right to Buy) 125,000 24.28 3.04M 125,000
2019-07-03 JEFFS ROGER Director M-Exempt A Common Stock 3,672 3.67 13.5K 3,672
2019-06-26 Coleman Mark Director P-Purchase A Common Stock 15,800 23.10 365.0K 668,848
2019-06-25 Coleman Mark Director P-Purchase A Common Stock 400 23.25 9.3K 653,048
2019-06-11 Pizzie Nick Officer P-Purchase A Common Stock 1,920 20.80 39.9K 1,920
2019-06-07 Saad Mark E Director A-Award A Stock Option (Right to Buy) 13,000 22.03 286.4K 13,000
2019-06-07 POTTER MYRTLE S Director A-Award A Stock Option (Right to Buy) 13,000 22.03 286.4K 13,000
2019-06-07 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 13,000 22.03 286.4K 13,000
2019-06-07 Coleman Mark Director A-Award A Stock Option (Right to Buy) 13,000 22.03 286.4K 13,000
2019-05-23 Saad Mark E Director P-Purchase A Common Stock 3,500 22.33 78.2K 7,002
2019-05-13 Coleman Mark Director P-Purchase A Common Stock 4,650 21.44 99.7K 652,648
2019-03-19 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 319,212 12.95 4.13M 319,212
2019-03-19 Saad Mark E Director A-Award A Stock Option (Right to Buy) 29,387 12.95 380.6K 29,387
2019-03-19 Pizzie Nick Officer P-Purchase A Common Stock 5,340 12.58 67.2K 36,340
2019-03-19 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 34,866 12.95 451.5K 34,866
2019-03-19 Coleman Mark Director P-Purchase A Common Stock 5,100 12.18 62.1K 5,100
2018-06-19 Pizzie Nick Officer P-Purchase A Common Stock 30,600 3.10 94.9K 31,000
2018-06-01 Saad Mark E Director A-Award A Stock Options (right to buy) 13,000 3.45 44.9K 13,000
2018-06-01 POTTER MYRTLE S Director A-Award A Stock Options (right to buy) 13,000 3.45 44.9K 13,000
2018-06-01 JEFFS ROGER Director A-Award A Stock Options (right to buy) 13,000 3.45 44.9K 13,000
2018-06-01 Coleman Mark Director A-Award A Stock Options (right to buy) 13,000 3.45 44.9K 13,000
2018-05-16 Pizzie Nick Officer 0 0.00 0
2018-03-12 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 187,628 2.85 534.7K 187,628
2018-03-12 Saad Mark E Director A-Award A Stock Option (Right to Buy) 32,602 2.85 92.9K 32,602
2018-03-12 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 39,948 2.85 113.9K 39,948
2018-03-12 Coleman Mark Director A-Award A Stock Option (Right to Buy) 27,297 2.85 77.8K 27,297
2017-08-04 Golubieski John Officer A-Award A Employee Stock Option (Right to Buy) 132,000 5.90 778.8K 132,000
2017-06-16 POTTER MYRTLE S Director A-Award A Stock Option (Right to Buy) 22,000 4.10 90.2K 22,000
2017-03-29 JEFFS ROGER Director M-Exempt A Common Stock 7,344 3.67 27.0K 11,718
2017-03-15 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 149,000 4.95 737.6K 149,000
2017-03-15 Saad Mark E Director A-Award A Stock Option (Right to Buy) 31,346 4.95 155.2K 31,346
2017-03-15 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 35,194 4.95 174.2K 35,194
2017-03-15 Coleman Mark Director A-Award A Stock Option (Right to Buy) 26,456 4.95 131.0K 26,456
2017-03-15 Ames Constance Officer A-Award A Employee Stock Option (Right to Buy) 25,000 4.95 123.8K 25,000
2016-05-27 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A Employee Stock Option (Right to Buy) 524,000 8.02 4.20M 524,000
2016-05-27 Saad Mark E Director A-Award A Stock Option (Right to Buy) 6,231 8.02 50.0K 6,231
2016-05-27 JEFFS ROGER Director A-Award A Stock Option (Right to Buy) 5,193 8.02 41.6K 5,193
2016-05-27 Coleman Mark Director A-Award A Stock Option (Right to Buy) 5,193 8.02 41.6K 5,193
2016-05-27 Ames Constance Officer A-Award A Employee Stock Option (Right to Buy) 25,000 8.02 200.5K 25,000
2015-12-23 Kaye Randall Officer P-Purchase A Common Stock 1,000 9.03 9.0K 6,022
2015-11-24 TABUTEAU HERRIOT Director / Officer / 10% Owner A-Award A 8% Convertible Note 7,229 5.94 42.9K 0
2015-11-24 Saad Mark E Director A-Award A 8% Convertible Note 3,502 5.94 20.8K 0
2015-11-24 Kaye Randall Officer A-Award A 8% Convertible Note 5,022 5.40 27.1K 0
2015-11-24 JEFFS ROGER Director A-Award A 8% Convertible Note 4,374 5.94 26.0K 0
2015-11-24 Coleman Mark Director A-Award A 8% Convertible Note 140,672 5.94 835.6K 0

Executive team

Top executives
EBIT / Employee
-248.8K
Shares Outstanding
51.15M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 835.0K 5.53M 2.83M 876.8K 205.0K 10.28M 81.36%
2 2025 Mark Jacobson, M.A. Chief Operating Officer 575.0K 2.08M 1.07M 388.0K 95.6K 4.21M 74.84%
3 2025 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 530.0K 1.82M 933.3K 358.0K 86.6K 3.73M 73.88%
4 2025 Hunter Murdock, Esq. General Counsel 530.0K 1.50M 766.6K 358.0K 72.6K 3.22M 70.21%
5 2025 Ari Maizel, M.B.A. Chief Commercial Officer 530.0K 1.50M 766.6K 358.0K 37.0K 3.19M 70.99%
6 2024 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 780.0K 2.83M 5.67M 955.5K 129.4K 10.36M 82.01%
7 2024 Mark Jacobson, M.A. Chief Operating Officer 552.0K 1.07M 2.13M 435.0K 59.0K 4.25M 75.36%
8 2024 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 505.0K 933.3K 1.87M 398.0K 53.5K 3.76M 74.54%
9 2024 Hunter Murdock, Esq. General Counsel 505.0K 766.5K 1.53M 398.0K 42.7K 3.25M 70.86%
10 2024 Ari Maizel, M.B.A. Chief Commercial Officer 510.0K 766.5K 1.53M 372.0K 16.7K 3.20M 71.90%
11 2023 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 750.0K 2.83M 5.67M 562.5K 83.0K 9.90M 85.90%
12 2023 Mark Jacobson, M.A. Chief Operating Officer 530.0K 1.07M 2.13M 265.0K 40.8K 4.04M 79.29%
13 2023 Ari Maizel, M.B.A. Chief Commercial Officer 445.0K 1.08M 2.15M 250.0K 3.92M 82.27%
14 2023 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 485.0K 933.7K 1.87M 243.0K 37.5K 3.57M 78.53%
15 2023 Hunter Murdock, Esq. General Counsel 485.0K 766.9K 1.53M 243.0K 29.3K 3.06M 75.23%
16 2022 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 685.0K 2.31M 4.69M 616.5K 19.5K 8.32M 84.13%
17 2022 Mark Jacobson, M.A. Chief Operating Officer 483.0K 1.00M 2.00M 289.8K 11.9K 3.79M 79.27%
18 2022 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 451.0K 858.5K 1.74M 270.6K 11.3K 3.33M 78.01%
19 2022 Hunter Murdock, Esq. General Counsel 450.0K 577.5K 1.17M 270.0K 15.4K 2.48M 70.40%
20 2021 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 685.0K 2.33M 4.67M 349.4K 20.7K 8.05M 86.90%
21 2021 Mark Jacobson, M.A. Chief Operating Officer 409.0K 999.9K 3.24M 139.1K 6.7K 4.79M 88.43%
22 2021 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 409.0K 866.6K 2.81M 139.1K 5.9K 4.23M 86.90%
23 2021 Hunter Murdock, Esq. General Counsel 350.0K 6.4K 12.8K 5.2K 374.4K 5.13%
24 2020 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 575.0K 1.62M 4.67M 448.5K 7.30M 85.99%
25 2020 Mark Jacobson, M.A. Chief Operating Officer 375.0K 461.6K 1.33M 195.0K 2.37M 75.90%
26 2020 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 375.0K 461.6K 1.33M 195.0K 2.37M 75.90%
27 2020 David Marek Former Chief Commercial Officer 392.4K 544.4K 936.8K 41.89%
28 2019 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 435.0K 3.95M 326.3K 4.72M 83.86%
29 2019 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 435.0K 3.95M 326.3K 4.72M 83.86%
30 2019 David Marek Chief Commercial Officer 128.3K 65.0K 2.55M 231.0K 2.97M 85.71%
31 2019 Mark Jacobson, M.A. Chief Operating Officer 310.0K 1.48M 162.8K 1.96M 75.83%
32 2019 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 325.0K 1.05M 195.0K 1.57M 66.88%
33 2019 David Marek Former Chief Commercial Officer 65.0K 65.0K 0.00%
34 2018 Herriot Tabuteau, M.D. Chief Executive Officer, President and Chairman of the Board 435.0K 361.4K 261.0K 1.06M 34.18%
35 2018 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 435.0K 361.4K 261.0K 1.06M 34.18%
36 2018 Nick Pizzie, CPA, M.B.A. Chief Financial Officer 203.1K 15.0K 313.9K 156.0K 688.0K 45.62%
37 2018 John Golubieski Former Chief Financial Officer 115.8K 65.8K 0.00%
38 2018 Nick Pizzie, C.P.A., M.B.A. Chief Financial Officer 15.0K 15.0K 0.00%
39 2017 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 435.0K 488.3K 200.1K 1.12M 43.46%
40 2017 John Golubieski Former Chief Financial Officer 131.9K 50.0K 519.6K 49.0K 750.4K 69.24%
41 2017 John Golubieski Chief Financial Officer 131.9K 50.0K 519.6K 49.0K 750.4K 69.24%
42 2017 Constance Ames Former Vice President, Finance and Treasurer 179.7K 81.9K 261.6K 31.31%
43 2016 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 435.0K 2.76M 174.0K 3.36M 81.90%
44 2016 Constance Ames Vice President, Finance and Treasurer 225.0K 53.3K 131.4K 409.8K 32.08%
45 2016 Constance Ames Former Vice President, Finance and Treasurer 225.0K 131.4K 53.3K 409.8K 32.08%
46 2016 Randall Kaye, M.D. Former Chief Medical Officer 273.3K 273.3K 0.00%
47 2015 Randall Kaye, M.D. Chief Medical Officer 126.7K 50.8K 527.6K 705.1K 74.83%
48 2015 Randall Kaye, M.D. Former Chief Medical Officer 126.7K 50.8K 527.6K 705.1K 74.83%
49 2015 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 300.0K 150.0K 450.0K 0.00%
50 2015 Constance Ames Vice President, Finance and Treasurer 175.0K 52.4K 161.6K 389.1K 41.55%
51 2014 Herriot Tabuteau, M.D. Chief Executive Officer and Chairman of the Board 250.0K 125.0K 375.0K 0.00%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-24 DEFA14A
2026-04-24 DEF 14A
2025-04-25 DEFA14A
2025-04-25 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-04 8-K
2026-05-04 10-Q
2026-04-30 8-K
2026-04-24 DEFA14A
2026-04-24 DEF 14A
2026-04-24 ARS
2026-04-23 4
2026-04-23 4
2026-04-23 4
2026-04-23 4

Executive team

NameTitleCompensationGender
Herriot Tabuteau Founder, Chairman, Chief Executive Officer & President 2M
Mark L. Jacobson Chief Operating Officer 1M male
Hunter Murdock General Counsel & Secretary 960.6K male
Nick Pizzie Chief Financial Officer 956.5K male
Ari Maizel Chief Commercial Officer 925.0K male
Darren Opland Director of Corporate Communications
ESG Rating
B-
BIOTECHNOLOGY
2025
E (Environmental)
56.4 / 56.3
Company / Sector avg.
S (Social)
63.8 / 62.4
Company / Sector avg.
G (Governance)
59.0 / 60.9
Company / Sector avg.
ESG Total
59.7 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits