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Arrowhead Pharmaceuticals, Inc. (ARWR)

USD74.11 -2.29 (-3.00%)
US NASDAQ Healthcare Biotechnology
Address 177 East Colorado Boulevard 91105
Pasadena, CA, US
CEO Christopher R. Anzalone
IPO 1993-12-16
CIK 879407 ISIN US04280A1007

Explore sections of this company profile

Also trades on London Stock Exchange · 0HI3.L (USD) NASDAQ Global Select · ARWR (USD)
Description

Arrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering and advancing innovative treatments for complex and challenging-to-treat diseases within the United States. The company's extensive therapeutic pipeline primarily leverages RNA interference (RNAi) technology. Among its advanced clinical programs are: ARO-AAT, a Phase II therapeutic targeting liver diseases associated with alpha-1 antitrypsin deficiency; ARO-APOC3, which is undergoing both Phase 2b and Phase 3 clinical evaluations for hypertriglyceridemia; ARO-ANG3, currently in Phase 2b development to reduce the production of angiopoietin-like protein 3; and ARO-HIF2, a Phase 1b candidate designed to treat clear cell renal cell carcinoma. Arrowhead also has several compounds in earlier clinical development, including ARO-HSD in Phase 1/2a for other liver diseases, ARO-ENaC in Phase 1/2a, aimed at decreasing the epithelial sodium channel alpha subunit in lung airways, and ARO-C3, also in Phase 1/2a, for complement-mediated diseases. Further expanding its diverse portfolio, the company is actively developing ARO-Lung2 for chronic obstructive pulmonary disorder (COPD), ARO-DUX4 for facioscapulohumeral muscular dystrophy, ARO-XDH for uncontrolled gout, and ARO-COV for COVID-19 and other pulmonary-borne pathogens. Beyond its core internal programs, Arrowhead is involved in the progression of JNJ-3989, a subcutaneously administered RNAi therapeutic for chronic hepatitis B virus infection; Olpasiran, intended to reduce apolipoprotein A production; and ARO-AMG1, which targets genetically validated cardiovascular pathways. Strategic collaborations are integral to Arrowhead's development efforts. The company holds a licensing and research agreement with Janssen Pharmaceuticals, Inc. for the co-development of ARO-JNJ1, ARO-JNJ2, and ARO-JNJ3, all RNAi therapeutics focused on liver-expressed targets. Additionally, Arrowhead has a licensing and research partnership with Takeda Pharmaceuticals U.S.A., Inc. to develop an RNAi therapeutic candidate specifically for liver disease.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD74.11 -2.29 (-3.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
1.27
Float Shares
122.04M
Free Float %
87.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+1.67% +3.32% +23.91% +23.85% +92.12% +19.05% +417.28% +98.14% +16.44% +1,411.28% -97.30%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (20 ratings, all time) Buy
Price Targets & DCF
Current price
74.11
Low 35.00 -52.8%
Consensus 82.33 +11.1%
Median 90.00 +21.4%
High 110.00 +48.4%
Ratings Trend (MoM) 85% Bullish
Rating 2026-05 Change
Strong Buy 4 +1
Buy 7 0
Hold 2 -1
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 1
100.00
+34.9%
Last Quarter 1
100.00
+34.9%
Last Year 14
80.21
+8.2%
All Time 27
59.84
-19.3%
Quality scores
Altman Z-Score
3.69
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
B-
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
5 / 5
High
ROA Score
5 / 5
High
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +23,258.2% Q1'26: -86.4% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +99.8% Q1'26: -133.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    +1.6% Q1'26: +111.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    +17.0% Q1'26: -191.6% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    Q1'26: -300.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +11.7% Q1'26: +5.9% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    2.22× Q1'26: -2.55× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.29) × ERP
WACC = 97% × Ke + 3% × Kd (24.4%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 74.11
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Sep 2014
actual
Sep 2015
actual
Sep 2016
actual
Sep 2017
actual
Sep 2018
actual
Sep 2019
actual
Sep 2020
actual
Sep 2021
actual
Sep 2022
actual
Sep 2023
actual
Sep 2024
actual
Sep 2025
actual
Sep 2026
11 Rev. Ana.
10 EPS Ana.
Sep 2027
10 Rev. Ana.
10 EPS Ana.
Sep 2028
10 Rev. Ana.
8 EPS Ana.
Sep 2029
5 Rev. Ana.
3 EPS Ana.
Sep 2030
5 Rev. Ana.
3 EPS Ana.
Revenue
175.0K
est: 235.9K (-25.8%)
382.0K
est: 484.3K (-21.1%)
158.3K
est: 741.6K (-78.6%)
31.41M
est: 30.72M (+2.2%)
16.14M
est: 59.12M (-72.7%)
168.80M
est: 165.95M (+1.7%)
87.99M
est: 132.14M (-33.4%)
138.29M
est: 134.59M (+2.7%)
243.23M
est: 255.58M (-4.8%)
240.74M
est: 35.47M (+578.6%)
3.55M
est: 62.14M (-94.3%)
829.45M
est: 764.56M (+8.5%)
470.89M
371.51M – 670.80M
-38.4% YoY
335.41M
157.14M – 507.36M
-28.8% YoY
599.39M
582.83M – 615.95M
+78.7% YoY
868.66M
580.32M – 1.28B
+44.9% YoY
1.69B
1.13B – 2.49B
+94.7% YoY
EBITDA
-49.76M
est: -49.60M (-0.3%)
-93.64M
est: -313.6K (-29,762.1%)
-76.43M
est: -480.1K (-15,819.1%)
-32.31M
est: -19.89M (-62.4%)
-51.24M
est: -38.27M (-33.9%)
65.63M
est: 61.30M (+7.1%)
-87.22M
est: -334.90M (+74.0%)
-132.58M
est: -333.04M (+60.2%)
-162.29M
est: -58.78M (-176.1%)
-175.67M
est: -22.40M (-684.3%)
-561.51M
est: -39.24M (-1,331.1%)
164.82M
est: -482.73M (+134.1%)
-297.32M
-423.53M – -234.57M
+38.4% YoY
-211.77M
-320.34M – -99.21M
+28.8% YoY
-378.45M
-388.91M – -368.00M
-78.7% YoY
-548.46M
-807.75M – -366.41M
-44.9% YoY
-1.07B
-1.57B – -713.40M
-94.7% YoY
EBIT
-51.10M
est: -52.17M (+2.0%)
-95.97M
est: -326.7K (-29,273.0%)
-79.69M
est: -500.3K (-15,828.8%)
-37.00M
est: -20.73M (-78.5%)
-55.94M
est: -39.88M (-40.3%)
61.19M
est: 47.74M (+28.2%)
-93.16M
est: -376.17M (+75.2%)
-140.85M
est: -359.29M (+60.8%)
-172.71M
est: -124.48M (-38.7%)
-188.17M
est: -23.57M (-698.4%)
-580.11M
est: -41.28M (-1,305.1%)
140.89M
est: -507.94M (+127.7%)
-312.85M
-445.65M – -246.82M
+38.4% YoY
-222.83M
-337.07M – -104.40M
+28.8% YoY
-398.21M
-409.22M – -387.21M
-78.7% YoY
-577.11M
-849.94M – -385.54M
-44.9% YoY
-1.12B
-1.65B – -750.66M
-94.7% YoY
Net Income
-58.63M
est: -50.48M (-16.2%)
-91.94M
est: -215.35M (+57.3%)
-81.72M
est: -172.28M (+52.6%)
-34.38M
est: -56.51M (+39.2%)
-54.45M
est: -11.70M (-365.2%)
67.98M
est: 56.24M (+20.9%)
-84.55M
est: -352.71M (+76.0%)
-140.85M
est: -349.03M (+59.6%)
-176.06M
est: -98.54M (-78.7%)
-205.28M
est: -470.79M (+56.4%)
-599.49M
est: -594.79M (-0.8%)
-1.63M
est: 33.03M (-104.9%)
-434.20M
-531.49M – -156.77M
-1,414.4% YoY
-595.99M
-905.15M – -247.42M
-37.3% YoY
-417.28M
-675.27M – 120.38M
+30.0% YoY
-226.00M
-364.89M – -128.48M
+45.8% YoY
381.49M
216.87M – 615.94M
+268.8% YoY
SGA
24.33M
est: 1.36M (+1,685.4%)
34.72M
est: 2.80M (+1,140.6%)
41.00M
est: 4.28M (+856.8%)
17.46M
est: 177.53M (-90.2%)
19.08M
est: 341.59M (-94.4%)
26.54M
est: 34.33M (-22.7%)
51.66M
est: 123.90M (-58.3%)
80.08M
est: 777.67M (-89.7%)
122.82M
est: 1.48B (-91.7%)
90.93M
est: 204.96M (-55.6%)
96.82M
est: 358.86M (-73.0%)
121.92M
est: 4.42B (-97.2%)
2.72B
2.15B – 3.87B
-38.4% YoY
1.94B
907.44M – 2.93B
-28.8% YoY
3.46B
3.37B – 3.56B
+78.7% YoY
5.02B
3.35B – 7.39B
+44.9% YoY
9.77B
6.52B – 14.38B
+94.7% YoY
EPS
-1.25
est: -0.74 (-68.9%)
-1.60
est: -1.61 (+0.6%)
-1.34
est: -1.29 (-4.0%)
-0.47
est: -0.42 (-11.2%)
-0.65
est: -0.09 (-642.9%)
0.72
est: 0.76 (-4.8%)
-0.84
est: -0.25 (-230.4%)
-1.36
est: -0.69 (-96.3%)
-1.67
est: -1.38 (-21.1%)
-1.91
est: -4.23 (+54.9%)
-5.00
est: -4.70 (-6.4%)
-0.01
est: 0.09 (-113.8%)
-3.03
-3.97 – -1.17
-3,528.3% YoY
-4.15
-6.77 – -1.85
-36.9% YoY
-2.85
-5.05 – 0.90
+31.3% YoY
-1.69
-2.73 – -0.96
+40.7% YoY
2.85
1.62 – 4.60
+268.8% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-04-21 Morgan Stanley Equal Weight Overweight Upgrade
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-05-06 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-05-05 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-05-04 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-05-01 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-30 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-29 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-28 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-27 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-24 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-23 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-22 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-21 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-20 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-17 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-16 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5
2026-04-15 B- 2/5 1/5 5/5 5/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
11.96M
OE per share TTM
0.16
Owner's Yield
0.11%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
87.5%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
117
Total invested
313.62M
Insider transactions (90d)
2
Beneficial owners (>5%)
27
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 (1) BlackRock, Inc. 12.71M 12.00% HC Delaware 2023-01-20
2 The Vanguard Group - 23-1945930 9.64M 9.22% 192.0K 9.36M 281.4K IA Pennsylvania 2022-02-09
3 Avoro Capital Advisors LLC 8.89M 7.20% 8.89M 8.89M IA, OO Delaware 2024-11-14
4 Behzad Aghazadeh 8.89M 7.20% 8.89M 8.89M IN Delaware 2024-11-14
5 OppenheimerFunds, Inc. 7.81M 8.46% 7.81M IA Colorado 2019-01-14
6 STATE STREET CORPORATION 6.35M 5.10% 5.94M HC MA 2024-10-16
7 Baker Bros. Advisors (GP) LLC 3.68M 5.90% 3.68M 3.68M HC Delaware 2016-02-16
8 Baker Bros. Advisors LP 3.68M 5.90% 3.68M 3.68M IA Delaware 2016-02-16
9 Felix J. Baker 3.68M 5.90% 3.68M 3.68M IN Delaware 2016-02-16
10 Julian C. Baker 3.68M 5.90% 3.68M 3.68M IN Delaware 2016-02-16
11 10. 3.12M 5.90% 3.12M 3.12M PN Delaware 2014-10-14
12 Oppenheimer Global Opportunities Fund 3.00M 5.04% 3.00M IV Colorado 2016-02-01
13 Point72 Capital Advisors, Inc. (formerly S.A.C. Capital Advisors, Inc.) 2.79M 6.20% 2.79M CO Delaware 2014-04-09
14 Millennium Management LLC 2.22M 4.90% 2.22M 2.22M OO Delaware 2014-04-08
15 Integrated Core Strategies (US) LLC 1.34M 3.00% 1.34M 1.34M OO Delaware 2014-04-08
16 Cubist Systematic Strategies, LLC 6.7K 4.00% 6.7K OO Delaware 2015-02-17
17 Steven A. Cohen 6.7K 4.00% 6.7K IN Delaware 2015-02-17
18 EverPoint Asset Management, LLC 0.00% OO Delaware 2015-02-17
19 Investments, LP 0.00% IA, OO Delaware 2020-02-14
20 Peter Kolchinsky 0.00% IN Massachusetts 2015-02-17
21 Point72 Asset Management, L.P. 0.00% PN Delaware 2015-02-17
22 Point72 Capital Advisors, Inc. 0.00% CO Delaware 2015-02-17
23 RA Capital Healthcare Fund, L.P. 0.00% PN Massachusetts 2015-02-17
24 RA Capital Management, LLC 0.00% IA Massachusetts 2015-02-17
25 S 0.00% HC, IN Delaware 2020-02-14
26 S.A.C. Capital Advisors, L.P. 0.00% PN Delaware 2014-04-09
27 Sigma Capital Management, LLC 0.00% OO Delaware 2014-04-09

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
117
-303 vs prev Q
New positions
24
Closed positions
311
Increased
64
Reduced
29
Put/Call ratio
0.00
Calls held
500.00
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 BLACKROCK, INC. 21.32M +1.1M (+5.4%) 1.42B +717.8M (+102.9%) 15.22% +0.676 pp 0.02% +0.012 pp USD21.20 +213.2% 6 qtrs
2 VANGUARD GROUP INC 15.29M -742.7K (-4.6%) 1.02B +462.2M (+83.6%) 10.92% -0.614 pp 0.01% +0.006 pp USD22.28 +198.0% 39 qtrs
3 AVORO CAPITAL ADVISORS LLC 10.63M -275.0K (-2.5%) 705.39M +329.5M (+87.6%) 7.59% -0.253 pp 6.78% +1.922 pp USD26.84 +147.4% 11 qtrs
4 FMR LLC 6.52M +760.6K (+13.2%) 432.89M +234.2M (+117.9%) 4.66% +0.513 pp 0.02% +0.012 pp USD30.57 +117.2% 30 qtrs
5 STATE STREET CORP 6.40M +6.5K (+0.1%) 425.15M +204.5M (+92.7%) 4.57% -0.029 pp 0.01% +0.007 pp USD25.59 +159.4% 40 qtrs
6 GEODE CAPITAL MANAGEMENT, LLC 3.26M +133.9K (+4.3%) 216.80M +108.8M (+100.7%) 2.33% +0.079 pp 0.01% +0.007 pp USD29.42 +125.7% 39 qtrs
7 SLATE PATH CAPITAL LP 2.52M -2.5M (-49.3%) 167.54M -4.3M (-2.5%) 1.80% -1.781 pp 2.26% -0.399 pp USD26.95 +146.3% 9 qtrs
8 BAKER BROS. ADVISORS LP 2.18M +504.9K (+30.2%) 144.44M +86.8M (+150.7%) 1.55% +0.352 pp 0.85% +0.429 pp USD33.82 +96.3% 3 qtrs
9 ARROWSTREET CAPITAL, LIMITED PARTNERSHIP 2.09M +6.3K (+0.3%) 138.62M +66.8M (+93.1%) 1.49% -0.006 pp 0.08% +0.036 pp USD34.01 +95.2% 3 qtrs
10 FRED ALGER MANAGEMENT, LLC 1.83M +1.5M (+497.4%) 121.69M +111.1M (+1,049.9%) 1.31% +1.088 pp 0.48% +0.436 pp USD61.05 +8.7% 2 qtrs
11 DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C) 1.83M +839.9K (+84.6%) 121.69M +87.4M (+255.3%) 1.31% +0.595 pp 1.55% +1.031 pp USD49.11 +35.2% 2 qtrs
12 DRIEHAUS CAPITAL MANAGEMENT LLC 1.77M -330.1K (-15.7%) 117.47M +45.1M (+62.2%) 1.26% -0.247 pp 0.80% +0.279 pp USD34.49 +92.5% 2 qtrs
13 NORGES BANK 1.70M +1.7M (+100.0%) 113.16M +113.2M (+100.0%) 1.22% +1.217 pp 0.01% +0.012 pp USD66.39 +0.0% 1 qtrs NEW
14 GOLDMAN SACHS GROUP INC 1.68M -96.4K (-5.4%) 111.37M +50.2M (+82.0%) 1.20% -0.078 pp 0.01% +0.006 pp USD25.07 +164.8% 39 qtrs
15 SIREN, L.L.C. 1.50M -1.2M (-43.8%) 99.62M +7.5M (+8.2%) 1.07% -0.849 pp 2.97% -0.631 pp USD19.28 +244.3% 6 qtrs
16 MORGAN STANLEY 1.48M -226.7K (-13.3%) 97.99M +39.3M (+66.9%) 1.05% -0.171 pp 0.01% +0.002 pp USD27.26 +143.5% 39 qtrs
17 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 1.35M +7.9K (+0.6%) 89.87M +43.5M (+93.6%) 0.97% -0.001 pp 0.01% +0.007 pp USD28.34 +134.3% 39 qtrs
18 NORTHERN TRUST CORP 1.35M +34.7K (+2.6%) 89.38M +44.1M (+97.6%) 0.96% +0.018 pp 0.01% +0.006 pp USD24.30 +173.2% 39 qtrs
19 FISHER ASSET MANAGEMENT, LLC 1.31M +257.9K (+24.5%) 87.09M +50.7M (+139.6%) 0.94% +0.179 pp 0.03% +0.017 pp USD34.00 +95.3% 7 qtrs
20 JANUS HENDERSON GROUP PLC 1.28M +306.9K (+31.5%) 85.00M +51.5M (+153.5%) 0.91% +0.214 pp 0.04% +0.023 pp USD42.31 +56.9% 23 qtrs
21 UBS ASSET MANAGEMENT AMERICAS INC 1.26M -499.1K (-28.4%) 83.68M +23.0M (+37.9%) 0.90% -0.366 pp 0.02% +0.005 pp USD19.75 +236.2% 31 qtrs
22 PICTET ASSET MANAGEMENT HOLDING SA 1.03M +737.7K (+253.5%) 68.64M +58.8M (+597.3%) 0.76% +0.549 pp 0.07% +0.057 pp USD51.71 +28.4% 10 qtrs
23 UBS GROUP AG 987.3K +69.1K (+7.5%) 65.55M +33.9M (+107.0%) 0.71% +0.045 pp 0.01% +0.006 pp USD25.29 +162.5% 39 qtrs
24 VESTAL POINT CAPITAL, LP 900.0K +900.0K (+100.0%) 59.75M +59.8M (+100.0%) 0.64% +0.643 pp 2.03% +2.032 pp USD66.39 +0.0% 1 qtrs NEW
25 BANK OF NEW YORK MELLON CORP 887.8K +73.3K (+9.0%) 58.94M +30.9M (+109.8%) 0.63% +0.048 pp 0.01% +0.005 pp USD29.68 +123.7% 39 qtrs
26 SUSQUEHANNA INTERNATIONAL GROUP, LLP 859.9K +325.8K (+61.0%) 57.09M +38.7M (+209.9%) 0.61% +0.230 pp 0.01% +0.005 pp USD45.62 +45.5% 39 qtrs
27 PRICE T ROWE ASSOCIATES INC /MD/ 838.8K +728.6K (+660.9%) 55.69M +51.9M (+1,364.4%) 0.60% +0.520 pp 0.01% +0.006 pp USD61.08 +8.7% 39 qtrs
28 WESTERN FINANCIAL CORP/CA 820.2K +— (+0.0%) 54.46M +26.2M (+92.5%) 0.60% +0.015 pp 21.60% +9.286 pp USD40.56 +63.7% 13 qtrs
29 PRINCIPAL FINANCIAL GROUP INC 715.5K -64.6K (-8.3%) 47.50M +20.6M (+76.6%) 0.53% -0.034 pp 0.02% +0.011 pp USD26.31 +152.3% 31 qtrs
30 ASSENAGON ASSET MANAGEMENT S.A. 684.9K +304.3K (+79.9%) 45.47M +32.3M (+246.4%) 0.50% +0.231 pp 0.06% +0.045 pp USD48.17 +37.8% 12 qtrs
31 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 663.3K +538.7K (+432.6%) 44.03M +39.7M (+925.2%) 0.47% +0.384 pp 0.12% +0.102 pp USD60.40 +9.9% 2 qtrs
32 BANK OF AMERICA CORP /DE/ 622.0K -138.7K (-18.2%) 41.30M +15.1M (+57.4%) 0.44% -0.103 pp 0.00% +0.001 pp USD25.90 +156.3% 39 qtrs
33 JPMORGAN CHASE & CO 611.9K -163.8K (-21.1%) 40.62M +13.9M (+51.8%) 0.46% -0.100 pp 0.00% +0.001 pp USD45.21 +46.8% 39 qtrs
34 RTW INVESTMENTS, LP 584.7K +584.7K (+100.0%) 38.82M +38.8M (+100.0%) 0.42% +0.418 pp 0.39% +0.389 pp USD66.39 +0.0% 1 qtrs NEW
35 ADAGE CAPITAL PARTNERS GP, L.L.C. 550.0K +550.0K (+100.0%) 36.51M +36.5M (+100.0%) 0.39% +0.393 pp 0.06% +0.055 pp USD66.39 +0.0% 1 qtrs NEW
36 INVESCO LTD. 547.8K +44.9K (+8.9%) 36.37M +19.0M (+109.7%) 0.39% +0.029 pp 0.01% +0.003 pp USD21.97 +202.2% 31 qtrs
37 PUBLIC SECTOR PENSION INVESTMENT BOARD 478.5K -60.8K (-11.3%) 31.77M +13.2M (+70.8%) 0.34% -0.046 pp 0.11% +0.039 pp USD17.38 +282.0% 4 qtrs
38 CITADEL ADVISORS LLC 474.3K +156.6K (+49.3%) 31.49M +20.5M (+187.4%) 0.34% +0.110 pp 0.00% +0.003 pp USD42.85 +54.9% 34 qtrs
39 SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC 470.0K +470.0K (+100.0%) 31.20M +31.2M (+100.0%) 0.34% +0.336 pp 0.65% +0.649 pp USD66.39 +0.0% 1 qtrs NEW
40 VOYA INVESTMENT MANAGEMENT LLC 422.7K +285.2K (+207.4%) 28.07M +23.3M (+491.7%) 0.30% +0.203 pp 0.03% +0.023 pp USD55.26 +20.1% 31 qtrs
41 WOODLINE PARTNERS LP 400.2K -600.0K (-60.0%) 26.57M -7.9M (-23.0%) 0.29% -0.434 pp 0.10% -0.059 pp USD27.02 +145.7% 12 qtrs
42 PRIVIUM FUND MANAGEMENT B.V. 398.2K -75.7K (-16.0%) 26.44M +10.1M (+61.7%) 0.29% -0.047 pp 4.87% +1.929 pp USD32.09 +106.9% 17 qtrs
43 LEGAL & GENERAL GROUP PLC 395.3K +8.9K (+2.3%) 26.24M +12.9M (+96.9%) 0.28% +0.004 pp 0.01% +0.003 pp USD29.58 +124.4% 31 qtrs
44 BALYASNY ASSET MANAGEMENT L.P. 376.2K -416.8K (-52.6%) 24.98M -2.4M (-8.7%) 0.27% -0.302 pp 0.03% -0.003 pp USD34.49 +92.5% 6 qtrs
45 ALYESKA INVESTMENT GROUP, L.P. 375.4K +375.4K (+100.0%) 24.92M +24.9M (+100.0%) 0.27% +0.268 pp 0.07% +0.070 pp USD66.39 +0.0% 1 qtrs NEW
46 EVENTIDE ASSET MANAGEMENT, LLC 370.0K +370.0K (+100.0%) 24.56M +24.6M (+100.0%) 0.26% +0.264 pp 0.38% +0.384 pp USD66.39 +0.0% 1 qtrs NEW
47 RHUMBLINE ADVISERS 352.4K -18.7K (-5.0%) 23.40M +10.6M (+82.8%) 0.25% -0.015 pp 0.02% +0.009 pp USD27.02 +145.7% 31 qtrs
48 NORDEA INVESTMENT MANAGEMENT AB 324.3K -48.0K (-12.9%) 21.57M +8.9M (+70.3%) 0.24% -0.029 pp 0.02% +0.007 pp USD38.58 +72.1% 20 qtrs
49 BARCLAYS PLC 321.8K +45.2K (+16.3%) 21.37M +16.0M (+298.8%) 0.23% +0.031 pp 0.01% +0.004 pp USD27.29 +143.3% 39 qtrs
50 NUVEEN, LLC 288.6K +10.2K (+3.7%) 19.16M +9.6M (+99.6%) 0.21% +0.006 pp 0.01% +0.003 pp USD14.64 +353.5% 4 qtrs
51 VOLORIDGE INVESTMENT MANAGEMENT, LLC 288.5K -114.1K (-28.3%) 19.15M +5.3M (+37.9%) 0.21% -0.084 pp 0.07% +0.021 pp USD34.49 +92.5% 2 qtrs
52 ABRDN PLC 286.1K -234.5K (-45.0%) 19.00M +1.0M (+5.8%) 0.21% -0.164 pp 0.03% +0.001 pp USD17.04 +289.6% 7 qtrs
53 FENGHE FUND MANAGEMENT PTE. LTD. 266.7K +266.7K (+100.0%) 17.71M +17.7M (+100.0%) 0.20% +0.197 pp 1.00% +0.997 pp USD66.39 +0.0% 1 qtrs NEW
54 AMERIPRISE FINANCIAL INC 257.5K -16.7K (-6.1%) 17.09M +7.6M (+80.8%) 0.18% -0.013 pp 0.00% +0.002 pp USD28.09 +136.3% 31 qtrs
55 TREXQUANT INVESTMENT LP 250.9K +250.9K (+100.0%) 16.66M +16.7M (+100.0%) 0.18% +0.179 pp 0.15% +0.149 pp USD66.39 +0.0% 7 qtrs
56 SWISS NATIONAL BANK 245.4K +31.3K (+14.6%) 16.29M +8.9M (+120.6%) 0.18% +0.021 pp 0.01% +0.005 pp USD31.58 +110.2% 31 qtrs
57 DEUTSCHE BANK AG\ 242.1K -4.0K (-1.6%) 16.07M +7.6M (+89.4%) 0.18% +0.004 pp 0.01% +0.002 pp USD44.54 +49.1% 39 qtrs
58 CAPTION MANAGEMENT, LLC 239.9K +239.9K (+100.0%) 15.93M +15.9M (+100.0%) 0.17% +0.171 pp 0.11% +0.109 pp USD66.39 +0.0% 1 qtrs NEW
59 FIRST TRUST ADVISORS LP 237.7K +29.8K (+14.3%) 15.78M +8.6M (+120.1%) 0.17% +0.020 pp 0.01% +0.006 pp USD38.49 +72.5% 2 qtrs
60 CLEARBRIDGE INVESTMENTS, LLC 208.1K -183.1K (-46.8%) 13.81M +322.3K (+2.4%) 0.15% -0.133 pp 0.01% +0.001 pp USD13.31 +398.8% 4 qtrs
61 RAYMOND JAMES FINANCIAL INC 198.4K -28.9K (-12.7%) 13.17M +5.3M (+68.0%) 0.14% -0.022 pp 0.00% +0.002 pp USD20.95 +216.9% 5 qtrs
62 HILLSDALE INVESTMENT MANAGEMENT INC. 193.9K +193.9K (+100.0%) 12.87M +12.9M (+100.0%) 0.14% +0.145 pp 0.36% +0.355 pp USD66.39 +0.0% 1 qtrs NEW
63 PINNACLE ASSOCIATES LTD 191.7K -11.6K (-5.7%) 12.72M +5.7M (+81.5%) 0.14% -0.005 pp 0.16% +0.070 pp USD13.76 +382.5% 4 qtrs
64 ALLIANCEBERNSTEIN L.P. 172.7K +16.8K (+10.8%) 11.46M +6.1M (+113.2%) 0.12% +0.011 pp 0.00% +0.002 pp USD54.26 +22.4% 31 qtrs
65 PEAK6 LLC 171.2K +94.1K (+122.0%) 11.37M +8.7M (+327.4%) 0.12% +0.067 pp 0.02% +0.017 pp USD52.02 +27.6% 2 qtrs
66 UNIVERSAL- BETEILIGUNGS- UND SERVICEGESELLSCHAFT MBH 159.5K -1.4K (-0.9%) 10.59M +5.0M (+90.8%) 0.12% +0.002 pp 0.02% +0.008 pp USD34.49 +92.5% 4 qtrs
67 SKANDINAVISKA ENSKILDA BANKEN AB (PUBL) 159.5K +159.5K (+100.0%) 10.59M +10.6M (+100.0%) 0.11% +0.114 pp 0.04% +0.043 pp USD66.39 +0.0% 1 qtrs NEW
68 SILVERCREST ASSET MANAGEMENT GROUP LLC 158.6K -114.4K (-41.9%) 10.53M +1.1M (+11.9%) 0.11% -0.083 pp 0.07% +0.010 pp USD23.57 +181.7% 12 qtrs
69 WELLS FARGO & COMPANY/MN 152.5K +72.3K (+90.1%) 10.12M +7.4M (+265.9%) 0.11% +0.051 pp 0.00% +0.001 pp USD43.79 +51.6% 39 qtrs
70 PRUDENTIAL FINANCIAL INC 152.2K +15.6K (+11.4%) 10.11M +5.4M (+114.4%) 0.11% +0.010 pp 0.01% +0.007 pp USD22.86 +190.4% 28 qtrs
71 NEW YORK STATE TEACHERS RETIREMENT SYSTEM 149.8K +1.3K (+0.9%) 9.94M +4.8M (+94.2%) 0.11% +0.004 pp 0.02% +0.009 pp USD32.71 +103.0% 27 qtrs
72 DIMENSIONAL FUND ADVISORS LP 147.4K -327.1K (-68.9%) 9.79M -6.6M (-40.2%) 0.11% -0.236 pp 0.00% -0.002 pp USD20.04 +231.3% 26 qtrs
73 AQR CAPITAL MANAGEMENT LLC 147.4K +4.5K (+3.2%) 9.78M +4.9M (+98.6%) 0.11% +0.003 pp 0.01% +0.002 pp USD16.57 +300.7% 4 qtrs
74 D. E. SHAW & CO., INC. 146.1K +125.8K (+619.5%) 9.70M +9.0M (+1,285.0%) 0.10% +0.090 pp 0.01% +0.005 pp USD61.96 +7.1% 2 qtrs
75 RHENMAN & PARTNERS ASSET MANAGEMENT AB 144.5K +144.5K (+100.0%) 9.59M +9.6M (+100.0%) 0.10% +0.103 pp 0.90% +0.897 pp USD66.39 +0.0% 1 qtrs NEW
76 WEALTH EFFECTS LLC 143.3K -25.2K (-14.9%) 9.51M +3.7M (+63.8%) 0.11% -0.016 pp 2.98% +1.107 pp USD57.44 +15.6% 17 qtrs
77 WCM INVESTMENT MANAGEMENT, LLC 138.9K +138.9K (+100.0%) 9.34M +9.3M (+100.0%) 0.10% +0.099 pp 0.02% +0.019 pp USD66.39 +0.0% 1 qtrs NEW
78 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 133.9K -4.1K (-3.0%) 8.89M +4.1M (+87.0%) 0.10% -0.004 pp 0.01% +0.006 pp USD25.06 +164.9% 7 qtrs
79 HIGHTOWER ADVISORS, LLC 133.2K +340.0 (+0.3%) 8.85M +4.3M (+93.0%) 0.10% +0.004 pp 0.01% +0.005 pp USD26.24 +153.0% 30 qtrs
80 JANE STREET GROUP, LLC 132.4K +109.4K (+475.7%) 8.79M +8.0M (+1,008.1%) 0.09% +0.078 pp 0.00% +0.001 pp USD57.77 +14.9% 5 qtrs
81 MARSHALL WACE, LLP 123.9K -1.3M (-91.4%) 8.22M -41.3M (-83.4%) 0.09% -0.945 pp 0.01% -0.043 pp USD15.88 +318.1% 5 qtrs
82 RUSSELL INVESTMENTS GROUP, LTD. 122.1K +109.2K (+847.8%) 8.11M +7.7M (+1,724.3%) 0.09% +0.078 pp 0.01% +0.008 pp USD63.32 +4.8% 28 qtrs
83 GREAT WEST LIFE ASSURANCE CO /CAN/ 118.8K -11.2K (-8.6%) 7.88M +3.5M (+79.6%) 0.08% -0.009 pp 0.01% +0.007 pp USD38.37 +73.0% 31 qtrs
84 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 118.4K +14.4K (+13.8%) 7.86M +4.3M (+119.1%) 0.08% +0.010 pp 0.01% +0.004 pp USD24.57 +170.2% 31 qtrs
85 SEI INVESTMENTS CO 112.3K +98.7K (+724.6%) 7.45M +7.0M (+1,487.1%) 0.08% +0.070 pp 0.01% +0.007 pp USD59.93 +10.8% 4 qtrs
86 WEISS ASSET MANAGEMENT LP 111.4K +111.4K (+100.0%) 7.39M +7.4M (+100.0%) 0.08% +0.080 pp 0.10% +0.104 pp USD66.39 +0.0% 1 qtrs NEW
87 FRANKLIN RESOURCES INC 107.4K -9.1K (-7.8%) 7.13M +3.1M (+77.4%) 0.08% -0.007 pp 0.00% +0.001 pp USD21.46 +209.4% 8 qtrs
88 NEUBERGER BERMAN GROUP LLC 100.4K +87.0K (+650.0%) 6.66M +6.2M (+1,343.6%) 0.07% +0.062 pp 0.01% +0.005 pp USD59.78 +11.1% 3 qtrs
89 LPL FINANCIAL LLC 100.3K +50.1K (+99.9%) 6.66M +4.9M (+284.8%) 0.07% +0.036 pp 0.00% +0.001 pp USD46.67 +42.3% 26 qtrs
90 INTEGRAL HEALTH ASSET MANAGEMENT, LLC 100.0K -125.0K (-55.6%) 6.64M -1.1M (-14.4%) 0.07% -0.090 pp 0.33% -0.195 pp USD34.49 +92.5% 5 qtrs
91 MANUFACTURERS LIFE INSURANCE COMPANY, THE 98.2K +35.2K (+55.8%) 6.55M +4.4M (+201.3%) 0.07% +0.025 pp 0.01% +0.004 pp USD51.50 +28.9% 39 qtrs
92 TFG ASSET MANAGEMENT GP LTD 96.9K +15.1K (+18.4%) 6.44M +3.6M (+128.0%) 0.07% +0.010 pp 1.36% +0.979 pp USD39.46 +68.2% 2 qtrs
93 THRIVENT FINANCIAL FOR LUTHERANS 95.0K -4.7K (-4.8%) 6.31M +2.9M (+83.3%) 0.07% -0.002 pp 0.01% +0.004 pp USD22.56 +194.3% 27 qtrs
94 VICTORY CAPITAL MANAGEMENT INC 92.6K +47.5K (+105.1%) 6.15M +4.6M (+294.7%) 0.07% +0.034 pp 0.00% +0.003 pp USD44.14 +50.4% 38 qtrs
95 PLATINUM INVESTMENT MANAGEMENT LTD 89.5K -21.5K (-19.4%) 5.94M +2.1M (+55.1%) 0.06% -0.016 pp 1.37% +1.126 pp USD24.93 +166.3% 12 qtrs
96 RAFFERTY ASSET MANAGEMENT, LLC 84.5K -29.9K (-26.1%) 5.61M +1.7M (+42.2%) 0.06% -0.022 pp 0.02% +0.007 pp USD29.79 +122.9% 28 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Ratio by volume
0.00
Bearish
Buys
0
Sells
4
Shares acquired
Shares disposed
23.1K
Cash buys
Cash sales
4.00
Net activity
-23,095
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-23 Hamilton James C Officer S-Sale D Common Stock 10,000 75.00 750.0K 226,958 D
2026-04-22 Apel Daniel Joseph Officer S-Sale D Common Stock 3,208 70.11 224.9K 172,792 D
2026-03-05 Hamilton James C Officer S-Sale D Common Stock 10,000 64.19 641.9K 236,958 D
2026-01-06 O'Brien Patrick Officer G-Gift D Common Stock 540 0.00 474,368 D
2026-01-06 Hamilton James C Officer A-Award A Common Stock 75,000 0.00 246,958 D
2026-01-06 Apel Daniel Joseph Officer A-Award A Common Stock 75,000 0.00 176,200 D
2026-01-05 O'Brien Patrick Officer S-Sale D Common Stock 313 68.00 21.3K 484,663 D
2026-01-05 Hamilton James C Officer S-Sale D Common Stock 309 68.00 21.0K 171,958 D
2026-01-02 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 7,416 65.88 488.6K 3,798,510 D
2025-12-31 O'Brien Patrick Officer G-Gift D Common Stock 560 0.00 524,401 D
2025-12-29 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 35,181 69.33 2.44M 3,822,471 D
2025-12-26 Ferrari Mauro Director S-Sale D Common Stock 7,530 70.00 527.1K 69,053 D
2025-12-22 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 2,574 68.85 177.2K 3,805,926 D
2025-12-19 Waddill William D. Director S-Sale D Common Stock 500 68.53 34.3K 56,563 D
2025-12-19 Vakiener Victoria Director S-Sale D Common Stock 1,960 68.39 134.0K 35,723 D
2025-12-19 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 827 68.48 56.6K 33,600 D
2025-12-19 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 8,147 68.01 554.1K 3,819,831 D
2025-12-17 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 35,750 64.51 2.31M 3,834,920 D
2025-12-16 Waddill William D. Director A-Award A Common Stock 7,819 0.00 64,930 D
2025-12-16 Vakiener Victoria Director A-Award A Common Stock 7,819 0.00 45,763 D
2025-12-16 PERRY MICHAEL S Director A-Award A Common Stock 7,819 0.00 123,059 D
2025-12-16 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 7,819 0.00 43,600 D
2025-12-16 Lu Hongbo Director A-Award A Common Stock 7,819 0.00 54,982 D
2025-12-16 INGRAM DOUGLAS S Director A-Award A Common Stock 7,819 0.00 46,215 D
2025-12-16 Ferrari Mauro Director A-Award A Common Stock 7,819 0.00 76,583 D
2025-12-16 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 8,416 60.51 509.3K 3,962,839 D
2025-12-15 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 21,321 69.28 1.48M 3,979,402 D
2025-12-12 Anzalone Christopher Richard Director / Officer A-Award A Common Stock 180,000 0.00 4,101,255 D
2025-12-05 PERRY MICHAEL S Director S-Sale D Common Stock 16,250 61.03 991.7K 115,240 D
2025-11-28 Ferrari Mauro Director S-Sale D Common Stock 8,750 56.39 493.4K 68,764 D
2025-10-01 Hamilton James C Officer S-Sale D Common Stock 20,000 35.00 700.0K 212,122 D
2025-09-12 Hamilton James C Officer S-Sale D Common Stock 15,000 30.00 450.0K 232,122 D
2025-09-02 Hamilton James C Officer S-Sale D Common Stock 15,000 25.00 375.0K 247,122 D
2025-08-15 Hamilton James C Officer S-Sale D Common Stock 9,389 20.00 187.8K 262,122 D
2025-08-13 Hamilton James C Officer S-Sale D Common Stock 611 20.00 12.2K 271,511 D
2025-04-15 Apel Daniel Joseph Officer Common Stock 0 0.00 101,200 D
2025-04-11 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 50,800 11.49 583.7K 3,921,255 D
2025-04-10 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 50,000 10.87 543.5K 3,972,055 D
2025-04-09 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 3,400 10.75 36.6K 4,023,672 D
2025-03-13 Anzalone Christopher Richard Director / Officer A-Award A Common Stock 340,000 0.00 4,113,802 D
2025-03-04 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 133,333 17.02 2.27M 3,773,802 D
2025-03-03 Anzalone Christopher Richard Director / Officer M-Exempt D Stock Option (right to buy Common Stock) 133,333 7.75 1.03M 51,726 D
2025-02-07 Anzalone Christopher Richard Director / Officer A-Award A Common Stock 9,550 20.10 192.0K 3,773,802 D
2025-02-06 INGRAM DOUGLAS S Director A-Award A Common Stock 38,396 20.09 771.4K 38,396 D
2025-01-23 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 959 21.00 20.1K 35,781 D
2025-01-07 O'Brien Patrick Officer S-Sale D Common Stock 8,000 19.69 157.5K 527,201 D
2025-01-07 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 8,000 19.70 157.6K 465,433 D
2025-01-06 O'Brien Patrick Officer S-Sale D Common Stock 9,526 20.10 191.5K 535,201 D
2025-01-06 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 9,402 20.10 189.0K 473,433 D
2025-01-06 Hamilton James C Officer S-Sale D Common Stock 21,758 19.68 428.2K 283,093 D
2025-01-04 O'Brien Patrick Officer A-Award A Common Stock 100,000 0.00 564,385 D
2025-01-04 Myszkowski Kenneth Allen Officer A-Award A Common Stock 100,000 0.00 500,600 D
2025-01-04 Hamilton James C Officer A-Award A Common Stock 100,000 0.00 304,851 D
2025-01-02 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 11,520 19.05 219.5K 3,764,252 D
2024-12-27 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 2,850 20.00 57.0K 36,740 D
2024-12-23 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 12,563 19.59 246.1K 3,775,772 D
2024-12-18 Waddill William D. Director A-Award A Common Stock 16,733 22.99 384.7K 57,111 D
2024-12-18 Vakiener Victoria Director A-Award A Common Stock 16,733 22.99 384.7K 37,944 D
2024-12-18 PERRY MICHAEL S Director A-Award A Common Stock 16,733 22.99 384.7K 131,490 D
2024-12-18 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 16,733 22.99 384.7K 39,590 D
2024-12-18 Lu Hongbo Director A-Award A Common Stock 16,733 22.99 384.7K 47,163 D
2024-12-18 Ferrari Mauro Director A-Award A Common Stock 16,733 22.99 384.7K 77,514 D
2024-12-18 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 5,799 22.12 128.3K 3,688,335 D
2024-12-17 Waddill William D. Director S-Sale D Common Stock 3,747 22.04 82.6K 40,378 D
2024-12-17 GIVEN DOUGLAS B Director S-Sale D Common Stock 547 22.04 12.1K 124,167 D
2024-12-16 Waddill William D. Director S-Sale D Common Stock 3,748 21.90 82.1K 44,125 D
2024-12-16 Vakiener Victoria Director S-Sale D Common Stock 8,994 21.91 197.1K 21,211 D
2024-12-16 GIVEN DOUGLAS B Director S-Sale D Common Stock 5,000 21.90 109.5K 124,714 D
2024-09-30 Lu Hongbo Director Common Stock 0 0.00 5,650 I
2024-07-02 Oliver Tracie Officer S-Sale D Common Stock 9,394 25.28 237.5K 127,107
2024-05-02 Vakiener Victoria Director S-Sale D Common Stock 1,799 23.31 41.9K 30,205
2024-04-01 Hamilton James C Officer S-Sale D Common Stock 6,000 28.03 168.2K 204,851
2024-03-20 Lu Hongbo Director P-Purchase A Common Stock 1,000 27.50 27.5K 33,680
2024-03-19 Lu Hongbo Director P-Purchase A Common Stock 1,000 28.00 28.0K 32,680
2024-03-18 Lu Hongbo Director P-Purchase A Common Stock 1,000 27.49 27.5K 31,680
2024-03-15 Lu Hongbo Director D Common Stock 0 0.00 30,680
2024-03-06 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 40,000 35.19 1.41M 400,600
2024-01-31 Anzalone Christopher Richard Director / Officer M-Exempt A Common Stock 57,499 14.54 836.0K 3,772,547
2024-01-12 Hamilton James C Officer S-Sale D Common Stock 4,238 36.47 154.6K 214,553
2024-01-11 Waddill William D. Director S-Sale D Common Stock 1,300 38.59 50.2K 47,870
2024-01-11 Vakiener Victoria Director S-Sale D Common Stock 3,620 37.87 137.1K 33,101
2024-01-11 GIVEN DOUGLAS B Director S-Sale D Common Stock 1,811 37.76 68.4K 130,811
2024-01-11 Ferrari Mauro Director S-Sale D Common Stock 1,000 38.63 38.6K 60,778
2024-01-05 San Martin Javier Officer S-Sale D Common Stock 3,100 35.03 108.6K 202,900
2024-01-05 Oliver Tracie Officer S-Sale D Common Stock 74 33.89 2.5K 136,501
2024-01-05 O'Brien Patrick Officer S-Sale D Common Stock 12,741 35.65 454.2K 464,385
2024-01-05 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 8,904 35.65 317.4K 440,600
2024-01-05 Hamilton James C S-Sale D Common Stock 12,343 35.65 440.0K 228,791
2024-01-04 San Martin Javier Officer A-Award A Common Stock 75,000 0.00 206,800
2024-01-04 Oliver Tracie Officer A-Award A Common Stock 75,000 0.00 136,575
2024-01-04 O'Brien Patrick Officer A-Award A Common Stock 85,000 0.00 487,226
2024-01-04 Myszkowski Kenneth Allen Officer A-Award A Common Stock 75,000 0.00 456,704
2024-01-04 Hamilton James C A-Award A Common Stock 75,000 0.00 250,934
2024-01-03 O'Brien Patrick Officer S-Sale D Common Stock 3,849 31.83 122.5K 408,726
2024-01-03 Hamilton James C S-Sale D Common Stock 500 33.30 16.7K 175,934
2024-01-02 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 4,634 30.74 142.4K 3,720,366
2023-12-20 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 12,000 28.54 342.5K 3,725,000
2023-12-15 Waddill William D. Director A-Award A Common Stock 14,987 25.41 380.8K 51,804
2023-12-15 Vakiener Victoria Director A-Award A Common Stock 14,987 25.41 380.8K 36,721
2023-12-15 PERRY MICHAEL S Director A-Award A Common Stock 14,987 25.41 380.8K 114,754
2023-12-15 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 14,987 25.41 380.8K 22,854
2023-12-15 GIVEN DOUGLAS B Director A-Award A Common Stock 14,987 25.41 380.8K 132,622
2023-12-15 Ferrari Mauro Director A-Award A Common Stock 14,987 25.41 380.8K 65,825
2023-11-20 San Martin Javier Officer S-Sale D Common Stock 14,758 28.73 424.0K 136,742
2023-10-25 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 24,338 24.21 589.2K 3,737,000
2023-09-28 Vakiener Victoria Director S-Sale D Common Stock 1,550 26.33 40.8K 21,734
2023-09-18 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 31,523 28.00 882.6K 3,787,570
2023-07-03 Oliver Tracie Officer S-Sale D Common Stock 8,925 35.31 315.1K 61,575
2023-06-30 Hamilton James C S-Sale D Common Stock 3,000 35.53 106.6K 188,484
2023-06-27 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 15,000 36.20 543.0K 381,704
2023-05-05 GIVEN DOUGLAS B Director S-Sale D Common Stock 6,500 40.90 265.9K 117,635
2023-05-04 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 25,992 40.02 1.04M 3,761,338
2023-05-03 Anzalone Christopher Richard Director / Officer M-Exempt D Stock Option (right to buy) 54,928 2.01 110.4K 516,980
2023-03-03 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 11,350 32.65 370.6K 7,867
2023-02-27 GIVEN DOUGLAS B Director S-Sale D Common Stock 875 32.62 28.5K 13,000
2023-01-10 Waddill William D. Director A-Award A Common Stock 4,593 0.00 4,593
2023-01-10 Vakiener Victoria Director A-Award A Common Stock 4,593 0.00 4,593
2023-01-10 PERRY MICHAEL S Director A-Award A Common Stock 7,867 0.00 99,767
2023-01-10 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 7,867 0.00 19,217
2023-01-10 GIVEN DOUGLAS B Director A-Award A Common Stock 4,593 0.00 4,593
2023-01-10 Ferrari Mauro Director A-Award A Common Stock 4,593 0.00 4,593
2023-01-10 De Backer Marianne Director A-Award A Common Stock 4,593 0.00 4,593
2023-01-09 Waddill William D. Director S-Sale D Common Stock 3,200 30.00 96.0K 28,950
2023-01-05 O'Brien Patrick Officer S-Sale D Common Stock 7,500 37.39 280.4K 413,375
2023-01-05 Hamilton James C Director S-Sale D Common Stock 7,230 37.40 270.4K 198,057
2023-01-04 San Martin Javier Officer A-Award A Common Stock 60,000 0.00 151,500
2023-01-04 Oliver Tracie Officer A-Award A Common Stock 500 0.00 70,500
2023-01-04 O'Brien Patrick Officer A-Award A Common Stock 65,000 0.00 428,375
2023-01-04 Myszkowski Kenneth Allen Officer A-Award A Common Stock 60,000 0.00 396,704
2023-01-04 Hamilton James C Director A-Award A Common Stock 60,000 0.00 205,287
2023-01-03 O'Brien Patrick Officer S-Sale D Common Stock 70 40.80 2.9K 372,125
2023-01-03 Hamilton James C Director S-Sale D Common Stock 300 39.56 11.9K 145,534
2022-12-29 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 30,625 40.00 1.23M 336,704
2022-12-21 O'Brien Patrick Officer M-Exempt A Common Stock 32,000 6.15 196.8K 380,875
2022-12-20 Anzalone Christopher Richard Officer A-Award A Common Stock 234,025 0.00 3,720,714
2022-12-16 Anzalone Christopher Richard Officer A-Award A Common Stock 18,375 0.00 3,486,689
2022-11-21 San Martin Javier Officer S-Sale D COMMON STOCK 200 30.62 6.1K 91,500
2022-09-30 Myszkowski Kenneth Allen Officer 0 0.00 0
2022-09-27 Anzalone Christopher Richard Director / Officer M-Exempt D Common Stock 1,542 31.21 48.1K 3,468,314
2022-07-08 Anzalone Christopher Richard Officer D-Return D Common Stock 551,197 0.00 3,508,938
2022-07-07 Anzalone Christopher Richard Director / Officer M-Exempt A Common Stock 2,501 14.54 36.4K 4,060,135
2022-05-02 Vakiener Victoria Director D Common Stock 0 0.00 17,181
2022-02-11 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 42,153 52.28 2.20M 4,121,016
2022-01-07 Waddill William D. Director A-Award A Common Stock 6,400 0.00 32,150
2022-01-07 PERRY MICHAEL S Director A-Award A Common Stock 6,400 0.00 91,900
2022-01-07 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 6,400 0.00 11,350
2022-01-07 GIVEN DOUGLAS B Director A-Award A Common Stock 6,400 0.00 116,268
2022-01-07 Ferrari Mauro Director A-Award A Common Stock 6,400 0.00 42,971
2022-01-07 De Backer Marianne Director A-Award A Common Stock 6,400 0.00 23,400
2022-01-07 Anzalone Christopher Richard Director / Officer M-Exempt A Common Stock 11,806 5.19 61.3K 4,057,634
2022-01-05 O'Brien Patrick Officer S-Sale D Common Stock 5,000 62.49 312.5K 353,591
2022-01-05 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 3,778 63.17 238.7K 467,791
2022-01-05 Hamilton James C S-Sale D Common Stock 700 63.68 44.6K 155,685
2022-01-04 Hamilton James C S-Sale D Common Stock 500 69.38 34.7K 161,875
2022-01-03 Waddill William D. Director S-Sale D Common Stock 272 66.25 18.0K 25,750
2022-01-03 PERRY MICHAEL S Director S-Sale D Common Stock 1,600 65.12 104.2K 85,772
2022-01-03 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 1,890 64.26 121.5K 7,110
2022-01-03 De Backer Marianne Director S-Sale D Common Stock 272 66.25 18.0K 17,000
2022-01-01 O'Brien Patrick Officer A-Award A Common Stock 60,000 0.00 381,375
2022-01-01 Myszkowski Kenneth Allen Officer A-Award A Common Stock 60,000 0.00 504,005
2022-01-01 Hamilton James C A-Award A Common Stock 55,000 0.00 181,250
2022-01-01 Anzalone Christopher Richard Director / Officer A-Award A Common Stock 800,000 0.00 4,045,828
2021-12-31 O'Brien Patrick Officer M-Exempt A Common Stock 28,000 6.15 172.2K 321,375
2021-12-28 GIVEN DOUGLAS B Director P-Purchase A Common Stock 655 66.37 43.5K 109,868
2021-12-28 Ferrari Mauro Director S-Sale D Common Stock 3,400 66.82 227.2K 36,571
2021-12-23 Anzalone Christopher Richard Director / Officer M-Exempt D Stock Option (right to buy Common Stock) 11,806 5.19 61.3K 773,227
2021-12-15 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 25,857 66.28 1.71M 3,253,165
2021-11-19 San Martin Javier Officer S-Sale D Common Stock 13,704 69.01 945.7K 116,796
2021-10-22 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 5,830 66.09 385.3K 3,279,022
2021-10-20 Anzalone Christopher Richard Director / Officer S-Sale D Common Stock 15,000 66.23 993.5K 3,329,022
2021-09-13 OLUKOTUN ADEOYE Y Director S-Sale D Common Stock 2,250 63.76 143.5K 11,750
2021-09-09 GIVEN DOUGLAS B Director S-Sale D Common Stock 5,000 65.24 326.2K 109,868
2021-06-24 De Backer Marianne Director S-Sale D Common Stock 5,000 89.85 449.3K 21,500
2021-06-22 Hassard James Officer S-Sale D Common Stock 3,625 89.22 323.4K 105,750
2021-06-22 GIVEN DOUGLAS B Director S-Sale D Common Stock 4,500 89.21 401.4K 114,868
2021-02-22 GIVEN DOUGLAS B Director S-Sale D Common Stock 1,125 88.73 99.8K 13,875
2021-02-08 O'Brien Patrick Officer M-Exempt D Stock Option (right to buy) 90,000 5.22 469.8K 60,000
2021-01-15 GIVEN DOUGLAS B Director S-Sale D Common Stock 3,000 83.28 249.8K 12,500
2021-01-14 Hamilton James C S-Sale D Common Stock 3,814 81.82 312.1K 126,250
2021-01-12 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 1,441 81.00 116.7K 444,005
2021-01-11 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 11,597 81.02 939.6K 445,446
2021-01-07 Hassard James Officer S-Sale D Common Stock 15,625 75.00 1.17M 109,375
2021-01-06 O'Brien Patrick Officer S-Sale D Common Stock 1,142 70.78 80.8K 317,233
2021-01-06 Myszkowski Kenneth Allen Officer S-Sale D Common Stock 1,100 70.75 77.8K 486,568
2021-01-06 Hamilton James C S-Sale D Common Stock 700 70.89 49.6K 154,925
2021-01-05 Hamilton James C S-Sale D Common Stock 1,925 73.93 142.3K 155,625
2021-01-04 Waddill William D. Director S-Sale D Common Stock 3,750 76.08 285.3K 30,250
2021-01-04 PERRY MICHAEL S Director S-Sale D Common Stock Sold 4,000 76.09 304.4K 90,000
2021-01-04 GIVEN DOUGLAS B Director S-Sale D Common Stock 4,000 76.08 304.3K 119,368
2021-01-01 Waddill William D. Director A-Award A Common Stock 9,000 0.00 34,000
2021-01-01 PERRY MICHAEL S Director A-Award A Common Stock 9,000 0.00 94,000
2021-01-01 OLUKOTUN ADEOYE Y Director A-Award A Common Stock 9,000 0.00 14,000
2021-01-01 O'Brien Patrick Officer A-Award A Common Stock 60,000 0.00 318,375
2021-01-01 Myszkowski Kenneth Allen Officer A-Award A Common Stock 60,000 0.00 487,668
2021-01-01 Hamilton James C A-Award A Common Stock 50,000 0.00 175,000
2021-01-01 GIVEN DOUGLAS B Director A-Award A Common Stock 9,500 0.00 123,368
2021-01-01 Ferrari Mauro Director A-Award A Common Stock 9,000 0.00 39,971
2021-01-01 De Backer Marianne Director A-Award A Common Stock 9,000 0.00 26,500
2021-01-01 Anzalone Christopher Richard Director / Officer A-Award A Common Stock 800,000 0.00 3,344,022
2020-12-30 Anzalone Christopher Richard Director / Officer G-Gift D Common Stock 599 0.00 2,544,022

Executive team

Top executives
EBIT / Employee
231.4K
Shares Outstanding
140.03M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Christopher Anzalone President and Chief Executive Officer 981.0K 6.81M 1.24M 2.5K 9.03M 75.42%
2 2025 Patrick O’Brien Chief Operating Officer 653.9K 1.98M 365.6K 31.6K 3.03M 65.31%
3 2025 James Hamilton Chief Medical Officer 617.5K 1.98M 354.6K 15.1K 2.97M 66.72%
4 2025 Kenneth Myszkowski Former Chief Financial Officer 496.8K 1.98M 155.8K 28.6K 2.66M 74.39%
5 2025 Daniel Apel Chief Financial Officer 232.2K 200.0K 1.29M 226.4K 9.3K 1.75M 73.34%
6 2025 Tracie Oliver Former Chief Commercial Officer 43.2K 43.2K 0.00%
7 2024 Christopher Anzalone President and Chief Executive Officer 951.0K 10.32M 1.15M 2.4K 12.42M 83.05%
8 2024 Patrick O’Brien Chief Operating Officer 605.3K 2.94M 378.0K 31.3K 3.95M 74.31%
9 2024 Patrick O’Brien Chief Operating Officer and General Counsel 605.3K 2.94M 378.0K 15.3K 3.93M 74.62%
10 2024 Kenneth Myszkowski Former Chief Financial Officer 592.4K 2.59M 314.5K 31.8K 3.53M 73.40%
11 2024 Kenneth Myszkowski Chief Financial Officer 592.4K 2.59M 314.5K 15.8K 3.51M 73.73%
12 2024 James Hamilton Chief Medical Officer 567.9K 2.59M 314.5K 15.3K 3.49M 74.26%
13 2024 James Hamilton Chief of Discovery and Translational Medicine 567.9K 2.59M 314.5K 15.3K 3.49M 74.26%
14 2024 Javier San Martin Former Chief Medical Officer 260.5K 2.59M 606.3K 3.46M 74.92%
15 2024 Tracie Oliver Former Chief Commercial Officer 484.1K 2.59M 3.0K 3.08M 84.17%
16 2023 Christopher Anzalone President and Chief Executive Officer 902.5K 8.31M 700.0K 1.5K 9.92M 83.83%
17 2023 Patrick O’Brien Chief Operating Officer 568.4K 2.48M 252.0K 30.7K 3.33M 74.41%
18 2023 Patrick O’Brien Chief Operating Officer and General Counsel 568.4K 2.48M 252.0K 14.7K 3.31M 74.77%
19 2023 Kenneth Myszkowski Former Chief Financial Officer 568.1K 2.28M 252.0K 30.2K 3.14M 72.88%
20 2023 Kenneth Myszkowski Chief Financial Officer 568.1K 2.28M 252.0K 14.2K 3.12M 73.25%
21 2023 Javier San Martin Former Chief Medical Officer 544.5K 2.28M 252.0K 14.7K 3.10M 73.80%
22 2023 Javier San Martin Chief Medical Officer 544.5K 2.28M 252.0K 14.7K 3.10M 73.80%
23 2023 James Hamilton Chief Medical Officer 511.2K 2.28M 236.3K 14.7K 3.05M 74.99%
24 2023 James Hamilton Chief of Discovery and Translational Medicine 511.2K 2.28M 236.3K 14.7K 3.05M 74.99%
25 2023 Tracie Oliver Former Chief Commercial Officer 647.3K 19.0K 188.0K 19.5K 873.8K 2.18%
26 2022 Christopher Anzalone President and Chief Executive Officer 863.4K 10.38M 783.3K 2.7K 12.03M 86.29%
27 2022 Kenneth Myszkowski Chief Financial Officer 509.6K 3.98M 238.1K 13.8K 4.74M 83.93%
28 2022 Patrick O’Brien Chief Operating Officer and General Counsel 500.5K 3.98M 235.6K 13.8K 4.73M 84.14%
29 2022 James Hamilton Chief of Discovery and Translational Medicine 450.4K 3.65M 212.6K 13.8K 4.32M 84.35%
30 2022 Tracie Oliver Former Chief Commercial Officer 111.2K 16.3K 2.52M 94.9K 4.9K 2.74M 91.72%
31 2022 Tracie Oliver Chief Commercial Officer 111.2K 16.3K 2.52M 94.9K 4.9K 2.74M 91.72%
32 2022 Javier San Martin Former Chief Medical Officer 479.2K 225.6K 704.7K 0.00%
33 2022 Javier San Martin Chief Medical Officer 479.2K 225.6K 704.7K 0.00%
34 2021 Christopher Anzalone President and Chief Executive Officer 837.0K 23.02M 845.0K 2.8K 24.70M 93.18%
35 2021 Patrick O’Brien General Counsel, Corp. Sect. and Chief Compliance Officer 479.8K 4.60M 239.6K 13.7K 5.34M 86.26%
36 2021 Patrick O’Brien Chief Operating Officer and General Counsel 479.8K 4.60M 239.6K 13.7K 5.34M 86.26%
37 2021 Kenneth Myszkowski Chief Financial Officer 484.9K 4.60M 231.2K 13.7K 5.33M 86.32%
38 2021 James Hamilton Chief of Discovery and Translational Medicine 426.1K 3.84M 233.6K 13.7K 4.51M 85.07%
39 2021 James Hamilton Sr. VP Discovery and Translational Medicine 426.1K 3.84M 233.6K 13.7K 4.51M 85.07%
40 2021 James Hassard Chief Commercial Officer 431.7K 353.1K 784.8K 0.00%
41 2021 Javier San Martin Chief Medical Officer 459.3K 185.4K 644.7K 0.00%
42 2020 Bruce D. Given Former Chief Operating Officer 409.6K 15.86M 76.7K 16.34M 97.02%
43 2020 Christopher Anzalone President and Chief Executive Officer 785.6K 12.69M 820.0K 2.9K 14.29M 88.75%
44 2020 James Hassard Chief Commercial Officer 302.4K 7.43M 170.0K 15.9K 7.92M 93.83%
45 2020 Javier San Martin Chief Medical Officer 380.8K 100.0K 7.23M 180.0K 12.8K 7.90M 91.47%
46 2020 Curt Bradshaw Former Chief Scientific Officer 338.5K 6.02M 13.5K 6.37M 94.48%
47 2020 Kenneth Myszkowski Chief Financial Officer 463.8K 5.39M 213.8K 12.8K 6.08M 88.65%
48 2020 Patrick O’Brien Chief Operating Officer and General Counsel 459.1K 4.44M 211.5K 12.8K 5.12M 86.66%
49 2020 Patrick O’Brien General Counsel, Corp. Sect. and Chief Compliance Officer 459.1K 4.44M 211.5K 12.8K 5.12M 86.66%
50 2020 James Hamilton Chief of Discovery and Translational Medicine 376.4K 2.85M 169.4K 12.8K 3.41M 83.63%
51 2020 James Hamilton Sr. VP Discovery and Translational Medicine 376.4K 2.85M 169.4K 12.8K 3.41M 83.63%
52 2019 Bruce D. Given Former Chief Operating Officer 488.8K 2.61M 850.0K 11.8K 3.96M 65.88%
53 2019 Bruce D. Given Chief Operating Officer 488.8K 2.61M 850.0K 11.8K 3.96M 65.88%
54 2019 Christopher Anzalone President and Chief Executive Officer 674.4K 1.54M 1.9K 2.22M 0.00%
55 2019 Kenneth Myszkowski Chief Financial Officer 422.5K 1.06M 251.6K 11.8K 1.74M 60.62%
56 2019 Patrick O’Brien General Counsel, Corp. Sect. and Chief Compliance Officer 422.3K 869.4K 249.4K 11.8K 1.55M 55.98%
57 2019 Patrick O’Brien General Counsel 422.3K 869.4K 249.4K 11.8K 1.55M 55.98%
58 2019 James Hamilton Sr. VP Discovery and Translational Medicine 351.8K 745.2K 109.6K 11.5K 1.22M 61.17%
59 2019 Zhen Li Senior Vice President, Chemistry and Non- Clinical Development 150.3K 931.5K 4.2K 1.09M 85.77%
60 2018 Christopher Anzalone President and Chief Executive Officer 643.0K 975.0K 1.9K 1.62M 0.00%
61 2018 Bruce D. Given Former Chief Operating Officer 450.4K 644.0K 445.9K 11.8K 1.55M 41.49%
62 2018 Bruce D. Given Chief Operating Officer 450.4K 644.0K 445.9K 11.8K 1.55M 41.49%
63 2018 Kenneth Myszkowski Chief Financial Officer 384.8K 276.0K 180.0K 12.2K 853.0K 32.36%
64 2018 Patrick O’Brien General Counsel 406.2K 220.8K 184.5K 11.8K 823.3K 26.82%
65 2018 Zhen Li Senior Vice President, Chemistry and Non- Clinical Development 287.5K 239.2K 150.0K 9.5K 686.1K 34.86%
66 2017 Christopher Anzalone President and Chief Executive Officer 616.1K 537.9K 715.4K 1.9K 1.87M 28.75%
67 2017 Bruce D. Given Chief Operating Officer 432.3K 589.0K 351.3K 11.6K 1.38M 42.55%
68 2017 Patrick O’Brien General Counsel 391.0K 224.8K 177.7K 11.6K 805.0K 27.92%
69 2017 Kenneth Myszkowski Chief Financial Officer 336.1K 224.8K 152.7K 11.8K 725.4K 30.98%
70 2017 Zhen Li Senior Vice President, Chemistry and Non- Clinical Development 247.4K 131.8K 120.0K 6.8K 506.0K 26.04%
71 2017 Peter Leone Vice President, Strategic Business Initiatives 261.8K 139.5K 71.4K 10.5K 483.2K 28.87%
72 2016 Bruce D. Given Chief Operating Officer 415.6K 922.5K 276.6K 251.8K 11.4K 1.88M 63.85%
73 2016 Christopher Anzalone President and Chief Executive Officer 592.4K 368.8K 448.6K 1.9K 1.41M 26.13%
74 2016 Kenneth Myszkowski Chief Financial Officer 321.7K 307.5K 184.4K 130.5K 12.4K 956.5K 51.42%
75 2016 Patrick O’Brien General Counsel 375.9K 276.6K 170.8K 11.4K 834.7K 33.13%
76 2016 David L. Lewis Chief Scientific Officer 270.1K 391.8K 11.3K 673.3K 58.20%
77 2016 Peter Leone Vice President, Strategic Business Initiatives 251.7K 230.5K 89.0K 10.5K 581.7K 39.62%
78 2016 Zhen Li Senior Vice President, Chemistry and Non- Clinical Development 237.9K 230.5K 72.1K 10.2K 550.7K 41.86%
79 2015 Christopher Anzalone President and Chief Executive Officer 564.9K 751.0K 426.8K 575.1K 1.9K 2.32M 50.77%
80 2015 Bruce D. Given Chief Operating Officer 396.4K 1.13M 312.1K 282.5K 11.4K 2.13M 67.58%
81 2015 Kenneth Myszkowski Chief Financial Officer 302.4K 375.5K 260.1K 123.1K 13.0K 1.07M 59.18%
82 2015 Patrick O’Brien General Counsel 286.4K 125.0K 156.6K 315.0K 146.0K 12.0K 1.04M 45.30%
83 2015 David L. Lewis Chief Scientific Officer 245.2K 520.2K 87.4K 10.7K 863.4K 60.25%
84 2015 Peter Leone Vice President, Strategic Business Initiatives 240.1K 442.2K 85.5K 10.5K 778.3K 56.82%
85 2014 Christopher Anzalone President and Chief Executive Officer 543.6K 3.05M 553.7K 664.0K 1.4K 4.82M 74.90%
86 2014 Bruce D. Given Chief Operating Officer 384.2K 1.82M 461.4K 233.0K 14.9K 2.91M 78.29%
87 2014 Kenneth Myszkowski Chief Financial Officer 293.4K 1.02M 461.4K 119.0K 11.6K 1.90M 77.72%
88 2014 David L. Lewis Chief Scientific Officer 226.4K 1.11M 84.0K 9.2K 1.43M 77.61%
89 2014 Peter Leone Vice President, Program Management and Strategy 222.8K 415.3K 32.0K 9.6K 679.7K 61.10%
90 2013 Christopher Anzalone President and Chief Executive Officer 504.8K 463.4K 486.0K 1.4K 1.46M 31.83%
91 2013 Bruce D. Given Chief Operating Officer 363.5K 334.9K 221.0K 10.4K 929.7K 36.02%
92 2013 Kenneth Myszkowski Chief Financial Officer 277.6K 173.7K 113.0K 9.6K 574.0K 30.27%
93 2013 David L. Lewis Chief Scientific Officer 199.6K 43.2K 216.8K 86.0K 8.5K 554.1K 39.13%
94 2013 Peter Leone Vice President, Program Management and Strategy 143.1K 83.4K 5.8K 232.3K 35.88%
95 2012 Christopher Anzalone President and Chief Executive Officer 473.0K 811.7K 200.0K 1.4K 1.49M 54.62%
96 2012 Bruce D. Given Chief Operating Officer 317.0K 605.4K 10.2K 932.6K 64.92%
97 2012 Bruce Given Chief Operating Officer 317.0K 605.4K 9.5K 931.9K 64.97%
98 2012 Kenneth Myszkowski Chief Financial Officer 262.0K 425.7K 60.0K 10.4K 758.1K 56.15%
99 2012 David L. Lewis Chief Scientific Officer 195.3K 86.4K 254.7K 5.9K 542.4K 46.96%
100 2012 Peter Leone Vice President, Program Management and Strategy 55.8K 2.6K 58.4K 0.00%
101 2006 Leon Ekchian President 147.7K 133.3K 250.0K 397.7K 33.52%
102 2006 Joseph T. Kingsley Interim President Chief Financial Officer 208.2K 75.0K 208.2K 36.03%
103 2006 R. Bruce Stewart Chief Executive Officer 202.9K 75.0K 202.9K 36.97%
104 2005 Joseph T. Kingsley Chief Financial Officer 190.1K 400.0K 190.1K 210.42%
105 2005 Joseph T. Kingsley Interim President Chief Financial Officer 190.1K 400.0K 190.1K 210.42%
106 2005 R. Bruce Stewart Chief Executive Officer 105.6K 250.0K 105.6K 236.81%
107 2005 Leon Ekchian President
108 2004 R. Bruce Stewart President and Chief Executive Officer 60.0K 60.0K 0.00%
109 2004 R. Bruce Stewart Chief Executive Officer 60.0K 250.0K 60.0K 416.67%
110 2004 Joseph T. Kingsley Chief Financial Officer 11.3K 11.3K 0.00%
111 2004 Leon Ekchian President
112 2003 R. Bruce Stewart President and Chief Executive Officer 25.0K 250.0K 25.0K 1,000.00%
113 2003 R. Bruce Stewart Chief Executive Officer 25.0K 25.0K 0.00%
114 2003 Joseph T. Kingsley Chief Financial Officer
115 2003 Leon Ekchian President
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-01-27 DEFA14A
2026-01-27 DEF 14A
2025-02-07 DEFA14A
2025-01-29 DEFA14A
2025-01-29 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 S-8
2026-05-07 8-K
2026-05-07 10-Q
2026-05-06 SC 13G
2026-04-29 SC 13G
2026-04-28 SC 13G
2026-04-24 SC 13G/A
2026-04-24 4
2026-04-24 4
2026-03-26 SC 13G/A

Executive team

NameTitleCompensationGender
Christopher R. Anzalone Chairman, Chief Executive Officer & President 2M
Patrick O'Brien Chief Operating Officer, General Counsel & Secretary 1M male
Daniel J. Apel Chief Financial Officer 1M male
James C. Hamilton Chief Medical Officer and Head of R&D 987.2K
Bruce D. Given Chief Medical Scientist 486.3K
Aaron Tan Head of Tax
Vincent Anzalone Head of Investor Relations & Vice President
Howard Lovy Director of Communications male
Mark Davis Founder and Founder & Director of Insert Therapeutics Inc & Calando
Mark Seefeld Head of Toxicology & Vice President
Tao Pei Chief Scientific Officer
ESG Rating
C+
BIOTECHNOLOGY
2008
E (Environmental)
63.9 / 56.3
Company / Sector avg.
S (Social)
64.0 / 62.4
Company / Sector avg.
G (Governance)
67.4 / 60.9
Company / Sector avg.
ESG Total
65.1 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity
Transaction Date Disclosed Representative District Owner Type Amount Link
2023-01-31 2023-02-24 Daniel Goldman NY10 Sale $1,001 - $15,000
Market share among peers
Peer comparison — filtered group (TTM)
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Dividend history

Earnings history

Earnings reports

Stock splits