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Appili Therapeutics Inc. (APLI.TO)

CAD0.02 +0.00 (+0.00%)
CA TSX Healthcare Biotechnology
Address #21-1344 Summer Street B3H 0A8
Halifax, NS, CA
CEO Donald D. Cilla Jr. Pharmd
IPO 2019-06-25
ISIN CA03783R1073

Explore sections of this company profile

Also trades on Other OTC · APLIF (USD) Toronto Stock Exchange · APLI.TO (CAD)
Description

Appili Therapeutics Inc., a Canadian biopharmaceutical firm headquartered in Halifax and founded in 2015, specializes in sourcing and advancing innovative treatments to address critical gaps in infectious disease medicine. The company's diverse pipeline includes Favipiravir, utilized for pandemic influenza and COVID-19, and the clinical-stage antifungal ATI-2307, which targets cryptococcal meningitis and invasive candidiasis. Other programs feature ATI-1503, a new class of gram-negative targeting antibiotics; ATI-1501, a taste-masked liquid oral metronidazole suspension; ATI-1801, a novel topical formulation of paromomycin for treating cutaneous leishmaniasis; and ATI-1701, a live-attenuated vaccine designed for Francisella tularensis. Additionally, Appili maintains a strategic collaboration with AiPharma Global Holdings LLC for the ongoing development of Avigan/Reeqonus (favipiravir).

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
CAD0.02 +0.00 (+0.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
59.9K
Beta
-0.23
Float Shares
113.93M
Free Float %
88.8%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% +0.00% +0.00% +0.00% -40.00% -40.00% +0.00% -62.50% -98.26% -98.13% -98.13%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
0.02
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-234.87
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
1 / 5
Low
ROE Score
5 / 5
High
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +143.1% Q1'26: +433.2% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -58.8% Q1'26: -515.8% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -2,268.5% Q1'26: -630.9% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -2,675.6% Q1'26: -5,845.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    Q1'26: +221.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +2.0% Q1'26: +9.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -1.98× Q1'26: -1.32× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.30) × ERP
WACC = 13% × Ke + 87% × Kd (28.5%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 0.02
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Mar 2020
actual
Mar 2022
actual
Mar 2023
actual
Mar 2025
actual
Mar 2026
1 Rev. Ana.
1 EPS Ana.
Revenue
199.1K
est: 200.0K (-0.4%)
1.39M
est: 828.0K (+68.0%)
334.2K
est: 334.2K (+0.0%)
100.4K
est: 100.4K (+0.0%)
244.2K
244.2K – 244.2K
+143.1% YoY
EBITDA
-5.63M
est: -40.0K (-13,975.5%)
-23.51M
est: -165.6K (-14,098.3%)
-8.10M
est: -66.8K (-12,025.8%)
360.6K
est: -20.1K (+1,894.9%)
-146.5K
-146.5K – -146.5K
-629.3% YoY
EBIT
-5.40M
est: -40.0K (-13,411.3%)
-23.52M
est: -165.6K (-14,105.9%)
-8.11M
est: -66.8K (-12,035.2%)
347.1K
est: -20.1K (+1,827.9%)
-146.5K
-146.5K – -146.5K
-629.3% YoY
Net Income
-5.42M
est: -16.98M (+68.1%)
-25.12M
est: -32.74M (+23.3%)
-9.24M
est: -9.70M (+4.7%)
-2.62M
est: -6.06M (+56.7%)
-6.19M
-6.19M – -6.19M
-2.0% YoY
SGA
4.25M
est: 2.03M (+109.5%)
5.32M
est: 8.41M (-36.6%)
4.62M
est: 3.39M (+36.3%)
2.85M
est: 1.02M (+179.8%)
2.93M
2.93M – 2.93M
+186.9% YoY
EPS
-0.16
est: -0.14 (-14.3%)
-0.38
est: -0.27 (-40.7%)
-0.08
est: -0.08 (-1.6%)
-0.02
est: -0.05 (+56.8%)
-0.05
-0.05 – -0.05
+0.0% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-26 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-25 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-22 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-21 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-20 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-19 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-14 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-13 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-12 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-11 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-06 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-05 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-04 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-05-01 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-30 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-28 C 2/5 1/5 5/5 1/5 1/5 1/5 1/5
2026-04-27 C- 1/5 1/5 4/5 1/5 1/5 1/5 1/5
2026-04-24 C- 1/5 1/5 4/5 1/5 1/5 1/5 1/5
2026-04-22 C- 1/5 1/5 4/5 1/5 1/5 1/5 1/5
2026-04-21 C- 1/5 1/5 4/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-16.4K
OE per share TTM
0.00
Owner's Yield
-0.85%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
10.7%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-8.2K
Shares Outstanding
128.37M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Donald D. Cilla Jr. Pharmd Chief Executive Officer, President & Director 714.9K
Gary S. Nabors Chief Development Officer 604.9K
Kenneth G. Howling Acting Chief Financial Officer 550.8K male
Carl Gelhaus Director of Non-Clinical Research 351.5K
Arthur Baran Director of New Product Development 336.6K male
Jenna McNeil Corporate Affairs & Communications Manager
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits