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Annovis Bio, Inc. (ANVS)
USD1.80
+0.09 (+5.26%)
US NYSE Healthcare Biotechnology
Address
1055 Westlakes Drive 19312
Malvern, PA, US
Malvern, PA, US
CEO
Maria L. Maccecchini
Website
annovisbio.com
IPO
2020-01-29
CIK 1477845 ISIN US03615A1088
Description
Annovis Bio, Inc. is a clinical-stage biopharmaceutical company focused on pioneering treatments for neurodegenerative disorders. The firm's flagship drug, Buntanetap, an oral medication, has successfully advanced through Phase 2a clinical trials for Alzheimer's and Parkinson's diseases. This compound is also currently being evaluated in clinical studies for Alzheimer's disease in individuals with Down Syndrome, as well as for various other chronic neurodegenerative conditions. Beyond Buntanetap, Annovis Bio is developing ANVS405 to offer protection against traumatic brain injury and stroke. Additionally, ANVS301 is progressing through Phase I clinical trials, aiming to enhance cognitive capabilities in the later stages of Alzheimer's disease and broader dementia. The company was founded in 2008 and operates out of Berwyn, Pennsylvania.
News Sentiment (7d)
Based on only 1 article — low confidence
Market Cap & Enterprise Value
Merger & Acquisition History
No mergers or acquisitions recorded for this company.
Technical Outlook
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Signal Summary
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| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
USD1.80
+0.09 (+5.26%)
Loading historical data…
Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
1.19
Float Shares
16.33M
Free Float %
83.0%
Price Performance
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| -3.29% | -10.43% | +10.16% | -13.45% | -32.01% | -40.46% | -2.83% | -84.84% | -92.50% | -78.52% | -78.52% |
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From
To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow
Revenue by geography
Revenue by segment
From
To
Revenue composition
From
To
By product
By geography
Financial Statements
Select metrics from the tables below to build your comparison.
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
Analyst Consensus (8 ratings, all time)
Buy
Price Targets & DCF
Current price
1.80
Low
21.00
+1,066.7%
Consensus
25.67
+1,326.1%
Median
26.00
+1,344.4%
High
30.00
+1,566.7%
DCF (Unlevered)
950.27
+52,692.9%
DCF (Levered)
950.39
+52,699.2%
DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.
Ratings Trend (MoM)
100% Bullish
| Rating | 2026-05 | Change |
|---|---|---|
| Strong Buy | 1 | 0 |
| Buy | 1 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
Price Target Summary
| Period | # Analysts | Avg Target |
|---|---|---|
| Last Month | — | — |
| Last Quarter | — | — |
| Last Year | — | — |
| All Time | 3 |
25.67
+1,326.1%
|
Quality scores
Altman Z-Score
-15.53
Distress
Piotroski F-Score
1 / 9
Weak
MOAT Score
3 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
-
Revenue growth Biotechnology: +1.6%—
-
EPS growth Biotechnology: +29.7%+99.9% ★ Q1'26: -40.0% (vs Q1'25)
-
FCF margin FCF growth · Biotechnology: +16.2%—
-
EBIT margin Biotechnology: +0.0%—
-
ROIC Biotechnology: -16.1%— Q1'26: +0.6% (vs Q1'25)
-
Share dilution Biotechnology: -3.4%+68.0% Q1'26: +127.6% (vs Q1'25)
-
Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×0.00× Q1'26: 0.00× (vs Q1'25)
Valuation Multiples
From
To
Price Forecast (3Y)
From
To
Theoretical Return — If Invested Today
* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.
Consensus Estimates
| Metric |
Dec 2024 actual |
Dec 2025 actual |
Dec 2026 2 Rev. Ana. 1 EPS Ana. |
Dec 2027 2 Rev. Ana. 1 EPS Ana. |
Dec 2028 2 Rev. Ana. 2 EPS Ana. |
Dec 2029 1 Rev. Ana. 1 EPS Ana. |
Dec 2030 1 Rev. Ana. 1 EPS Ana. |
|---|---|---|---|---|---|---|---|
| Revenue |
—
|
—
|
10.95M
10.95M – 10.95M
|
16.69M
16.69M – 16.69M
+52.5% YoY
|
50.53M
50.53M – 50.53M
+202.8% YoY
|
208.74M
208.74M – 208.74M
+313.1% YoY
|
385.00M
385.00M – 385.00M
+84.4% YoY
|
| EBITDA |
-26.69M
|
-29.70M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EBIT |
-26.69M
|
-29.70M
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| Net Income |
-24.59M
est: -23.38M (-5.2%)
|
-28.85M
est: -26.82M (-7.6%)
|
-26.00M
-26.00M – -26.00M
+3.1% YoY
|
-26.92M
-26.92M – -26.92M
-3.6% YoY
|
-37.20M
-49.60M – -24.80M
-38.2% YoY
|
-9.04M
-9.04M – -9.04M
+75.7% YoY
|
37.61M
37.61M – 37.61M
+515.9% YoY
|
| SGA |
6.70M
|
4.48B
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
—
— – —
|
| EPS |
-2,018.50
est: -1.92 (-105,304.7%)
|
-1.40
est: -1.30 (-7.3%)
|
-1.27
-1.27 – -1.27
+3.1% YoY
|
-1.31
-1.31 – -1.31
-3.6% YoY
|
-1.81
-2.41 – -1.21
-38.2% YoY
|
-0.44
-0.44 – -0.44
+75.7% YoY
|
1.83
1.83 – 1.83
+515.9% YoY
|
Historical Ratings (3M)
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-12 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-11 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-08 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-07 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-06 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-05 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-04 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-05-01 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-30 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-29 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-28 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-27 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-24 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-23 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-22 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-21 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-20 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-17 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
| 2026-04-16 | C- | 1/5 | 3/5 | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 |
Owner Earnings
Owner's Earnings (history)
Owner's Earnings history not available.
Owner alignment
Owner's Earnings TTM
—
OE per share TTM
—
Owner's Yield
—
Maintenance CapEx ratio
—
Maint CapEx / Avg PPE
—
Ownership Overview
Ownership breakdown
At a glance
Institutional holders
29
Total invested
3.23M
Insider transactions (90d)
0
Beneficial owners (>5%)
3
Beneficial owners (>5%)
| # | Reporting person | Amount owned | % of class | Sole voting | Shared voting | Sole dispositive | Shared dispositive | Type | Citizenship | Filing date | SEC filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Maria L. Maccecchini | 1.41M | 19.40% | 1.41M | — | 1.41M | 11.00 | IN | — | 2020-04-20 | ↗ |
| 2 | Identification Nos. of above persons (. | 573.9K | 5.60% | 573.9K | — | 573.9K | — | IN | States | 2023-11-08 | ↗ |
| 3 | 27-4413262 | 548.9K | 5.40% | 548.9K | — | 548.9K | — | OO | Maryland | 2023-11-08 | ↗ |
Institutional Activity (13F)
Institutional ownership trend
From
To
13F snapshot — 2026 Q1
Investors holding
29
-30 vs prev Q
New positions
7
Closed positions
33
Increased
10
Reduced
6
Put/Call ratio
0.00
Calls held
10.0K
Puts held
—
Top institutional holders
| # | Investor | Shares / Δ | Mkt value / Δ | Own% / Δ | Weight% / Δ | Avg px / Perf. | Hold / Status |
|---|---|---|---|---|---|---|---|
| 1 | — | 27.3K +27.3K (+100.0%) | 94.35M +94.4M (+100.0%) | 0.14% +0.139 pp | 0.10% +0.099 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 2 | VANGUARD GROUP INC | 923.2K +185.2K (+25.1%) | 3.19M +1.7M (+109.1%) | 4.69% +0.903 pp | 0.00% +0.000 pp | USD16.19 -78.6% | 20 qtrs — |
| 3 | MARSHALL WACE, LLP | 725.9K +725.9K (+100.0%) | 2.51M +2.5M (+100.0%) | 3.69% +3.687 pp | 0.00% +0.002 pp | USD3.46 +0.0% | 3 qtrs — |
| 4 | TWO SIGMA INVESTMENTS, LP | 551.8K +551.8K (+100.0%) | 1.91M +1.9M (+100.0%) | 2.80% +2.803 pp | 0.00% +0.003 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 222.1K +38.0K (+20.6%) | 768.7K +387.4K (+101.6%) | 1.13% +0.183 pp | 0.00% +0.000 pp | USD12.35 -72.0% | 20 qtrs — |
| 6 | D.A. DAVIDSON & CO. | 160.8K +160.8K (+100.0%) | 556.3K +556.3K (+100.0%) | 0.82% +0.817 pp | 0.00% +0.003 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 7 | BLACKROCK, INC. | 139.5K +58.9K (+73.0%) | 482.8K +315.8K (+189.1%) | 0.71% +0.295 pp | 0.00% +0.000 pp | USD5.96 -41.9% | 6 qtrs — |
| 8 | NORTHERN TRUST CORP | 120.9K -198.0 (-0.2%) | 418.2K +167.6K (+66.9%) | 0.61% -0.007 pp | 0.00% +0.000 pp | USD4.84 -28.5% | 11 qtrs — |
| 9 | MERIT FINANCIAL GROUP, LLC | 81.3K +— (+0.0%) | 281.4K +113.0K (+67.1%) | 0.41% -0.004 pp | 0.00% +0.001 pp | USD7.06 -51.0% | 14 qtrs — |
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 78.0K +32.0K (+69.6%) | 269.9K +174.7K (+183.4%) | 0.40% +0.160 pp | 0.00% +0.000 pp | USD5.59 -38.1% | 8 qtrs — |
| 11 | JANE STREET GROUP, LLC | 74.4K +74.4K (+100.0%) | 257.4K +257.4K (+100.0%) | 0.38% +0.378 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 12 | STATE STREET CORP | 74.0K +35.6K (+92.6%) | 256.2K +176.6K (+222.0%) | 0.38% +0.179 pp | 0.00% +0.000 pp | USD24.10 -85.6% | 19 qtrs — |
| 13 | GROUP ONE TRADING, L.P. | 69.1K +34.5K (+99.6%) | 239.2K +167.5K (+233.7%) | 0.35% +0.174 pp | 0.00% +0.000 pp | USD4.06 -14.8% | 6 qtrs — |
| 14 | OMERS ADMINISTRATION CORP | 62.1K +62.1K (+100.0%) | 214.9K +214.9K (+100.0%) | 0.32% +0.316 pp | 0.00% +0.002 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 15 | TWO SIGMA ADVISERS, LP | 45.2K +45.2K (+100.0%) | 156.5K +156.5K (+100.0%) | 0.23% +0.230 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 16 | CITADEL ADVISORS LLC | 43.4K +4.8K (+12.4%) | 150.2K +70.3K (+87.9%) | 0.22% +0.022 pp | 0.00% +0.000 pp | USD7.64 -54.7% | 9 qtrs — |
| 17 | GREENWICH WEALTH MANAGEMENT LLC | 42.4K -5.0K (-10.5%) | 147.0K +49.0K (+50.0%) | 0.22% -0.028 pp | 0.01% +0.002 pp | USD7.30 -52.6% | 9 qtrs — |
| 18 | WESCOTT FINANCIAL ADVISORY GROUP, LLC | 41.6K +— (+0.0%) | 144.0K +57.8K (+67.2%) | 0.21% -0.002 pp | 0.01% +0.005 pp | USD31.75 -89.1% | 18 qtrs — |
| 19 | FIRST NATIONAL TRUST CO | 40.0K +25.0K (+166.7%) | 138.4K +107.4K (+345.7%) | 0.20% +0.126 pp | 0.00% +0.004 pp | USD2.73 +26.7% | 4 qtrs — |
| 20 | UBS GROUP AG | 30.6K +30.0K (+4,740.9%) | 106.0K +104.7K (+7,993.5%) | 0.16% +0.152 pp | 0.00% +0.000 pp | USD3.44 +0.6% | 11 qtrs — |
| 21 | VIRTU FINANCIAL LLC | 26.3K +26.3K (+100.0%) | 91.0K +91.0K (+100.0%) | 0.13% +0.134 pp | 0.00% +0.004 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 22 | DAKOTA WEALTH MANAGEMENT | 26.2K +26.2K (+100.0%) | 90.7K +90.7K (+100.0%) | 0.13% +0.133 pp | 0.00% +0.002 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 23 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 24.4K +5.0K (+25.8%) | 84.4K +44.3K (+110.2%) | 0.12% +0.024 pp | 0.00% +0.001 pp | USD20.62 -83.2% | 20 qtrs — |
| 24 | STERLING INVESTMENT ADVISORS, LTD. | 23.4K +— (+0.0%) | 81.0K +32.5K (+67.1%) | 0.12% -0.001 pp | 0.01% +0.006 pp | USD9.38 -63.1% | 22 qtrs — |
| 25 | NEWEDGE ADVISORS, LLC | 20.5K +20.5K (+100.0%) | 70.9K +70.9K (+100.0%) | 0.10% +0.104 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 26 | BANK OF NEW YORK MELLON CORP | 20.1K +1.0K (+5.2%) | 69.4K +30.0K (+75.9%) | 0.10% +0.004 pp | 0.00% +0.000 pp | USD51.59 -93.3% | 19 qtrs — |
| 27 | WEALTHSPIRE ADVISORS, LLC | 20.0K +10.0K (+100.0%) | 69.2K +48.5K (+234.3%) | 0.10% +0.050 pp | 0.00% +0.000 pp | USD9.56 -63.8% | 12 qtrs — |
| 28 | ROBERTSON STEPHENS WEALTH MANAGEMENT, LLC | 18.6K +18.6K (+100.0%) | 64.3K +64.3K (+100.0%) | 0.09% +0.094 pp | 0.00% +0.002 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 29 | GILL CAPITAL PARTNERS, LLC | 18.6K +18.6K (+100.0%) | 64.3K +64.3K (+100.0%) | 0.09% +0.094 pp | 0.02% +0.020 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 30 | CWA ASSET MANAGEMENT GROUP, LLC | 17.0K +4.0K (+30.8%) | 58.8K +31.9K (+118.6%) | 0.09% +0.020 pp | 0.00% +0.001 pp | USD2.47 +40.1% | 3 qtrs — |
| 31 | KOSHINSKI ASSET MANAGEMENT, INC. | 15.0K +15.0K (+100.0%) | 51.9K +51.9K (+100.0%) | 0.08% +0.076 pp | 0.00% +0.003 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 32 | JPMORGAN CHASE & CO | 14.9K +— (+0.0%) | 51.6K +20.7K (+67.1%) | 0.08% -0.001 pp | 0.00% +0.000 pp | USD3.45 +0.3% | 6 qtrs — |
| 33 | WELLS FARGO & COMPANY/MN | 14.3K +4.6K (+46.8%) | 49.5K +29.3K (+145.4%) | 0.07% +0.023 pp | 0.00% +0.000 pp | USD22.76 -84.8% | 20 qtrs — |
| 34 | TOWER RESEARCH CAPITAL LLC (TRC) | 13.7K +12.6K (+1,238.1%) | 47.3K +45.2K (+2,137.2%) | 0.07% +0.064 pp | 0.00% +0.001 pp | USD3.36 +3.0% | 14 qtrs — |
| 35 | RFG ADVISORY, LLC | 12.5K +12.5K (+100.0%) | 43.1K +43.1K (+100.0%) | 0.06% +0.063 pp | 0.00% +0.001 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 36 | RKL WEALTH MANAGEMENT LLC | 10.0K +10.0K (+100.0%) | 34.6K +34.6K (+100.0%) | 0.05% +0.051 pp | 0.00% +0.003 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 37 | MORGAN STANLEY | 9.9K +2.5K (+34.0%) | 34.3K +19.0K (+124.0%) | 0.05% +0.012 pp | 0.00% +0.000 pp | USD3.22 +7.5% | 22 qtrs — |
| 38 | BRYN MAWR TRUST CO | 9.4K +— (+0.0%) | 32.5K +13.1K (+67.1%) | 0.05% -0.001 pp | 0.00% +0.000 pp | USD8.06 -57.1% | 6 qtrs — |
| 39 | COVESTOR LTD | 2.3K +— (+0.0%) | 8.0K +3.0K (+60.0%) | 0.01% 0.000 pp | 0.00% +0.001 pp | USD1.63 +112.3% | 4 qtrs — |
| 40 | FNY INVESTMENT ADVISERS, LLC | 2.0K +— (+0.0%) | 6.0K +2.0K (+50.0%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD2.07 +67.1% | 2 qtrs — |
| 41 | SBI SECURITIES CO., LTD. | 1.5K +96.0 (+6.7%) | 5.3K +2.3K (+78.4%) | 0.01% +0.000 pp | 0.00% +0.000 pp | USD2.54 +36.2% | 5 qtrs — |
| 42 | GALLACHER CAPITAL MANAGEMENT LLC | 10.0K +10.0K (+100.0%) | 5.0K +5.0K (+100.0%) | 0.05% +0.051 pp | 0.00% +0.002 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 43 | SRS CAPITAL ADVISORS, INC. | 1.0K +1.0K (+100.0%) | 3.5K +3.5K (+100.0%) | 0.01% +0.005 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 44 | ROCKEFELLER CAPITAL MANAGEMENT L.P. | 1.0K +— (+0.0%) | 3.5K +1.4K (+67.1%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD2.07 +67.1% | 2 qtrs — |
| 45 | DINUZZO PRIVATE WEALTH, INC. | 1.0K +— (+0.0%) | 3.5K +1.2K (+49.8%) | 0.01% 0.000 pp | 0.00% +0.000 pp | USD5.03 -31.2% | 5 qtrs — |
| 46 | PNC FINANCIAL SERVICES GROUP, INC. | 360.00 +— (+0.0%) | 1.2K +501.0 (+67.2%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.50 +130.7% | 4 qtrs — |
| 47 | RHUMBLINE ADVISERS | 350.00 +— (+0.0%) | 1.2K +487.0 (+67.3%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD8.06 -57.1% | 6 qtrs — |
| 48 | LARSON FINANCIAL GROUP LLC | 300.00 +— (+0.0%) | 1.0K +417.0 (+67.1%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD1.83 +89.1% | 4 qtrs — |
| 49 | ROYAL BANK OF CANADA | 314.00 +314.0 (+100.0%) | 1.0K +1.0K (+100.0%) | 0.00% +0.002 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 3 qtrs — |
| 50 | ADVISOR GROUP HOLDINGS, INC. | 210.00 +— (+0.0%) | 727.00 +298.0 (+69.5%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD16.15 -78.6% | 24 qtrs — |
| 51 | IFP ADVISORS, INC | 210.00 +— (+0.0%) | 727.00 +292.0 (+67.1%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD2.12 +63.2% | 3 qtrs — |
| 52 | BANK OF AMERICA CORP /DE/ | 207.00 +62.0 (+42.8%) | 716.00 +416.0 (+138.7%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD7.08 -51.1% | 18 qtrs — |
| 53 | GLOBAL RETIREMENT PARTNERS, LLC | 100.00 +100.0 (+100.0%) | 346.00 +346.0 (+100.0%) | 0.00% +0.001 pp | 0.00% +0.000 pp | USD3.46 +0.0% | 1 qtrs NEW |
| 54 | CITIGROUP INC | 1.00 +1.0 (+100.0%) | 3.00 +3.0 (+100.0%) | 0.00% +0.000 pp | 0.00% +0.000 pp | USD3.00 +15.3% | 1 qtrs NEW |
| 55 | STEWARD PARTNERS INVESTMENT ADVISORY, LLC | — -1.0K (-100.0%) | — -2.1K (-100.0%) | 0.00% -0.005 pp | 0.00% +0.000 pp | USD— | 4 qtrs SOLD |
| 56 | SIMPLEX TRADING, LLC | — -4.1K (-100.0%) | — -8.0K (-100.0%) | 0.00% -0.021 pp | 0.00% +0.000 pp | USD— | 6 qtrs SOLD |
| 57 | HRT FINANCIAL LP | — -37.6K (-100.0%) | — -77.0K (-100.0%) | 0.00% -0.193 pp | 0.00% 0.000 pp | USD— | 3 qtrs SOLD |
| 58 | XTX TOPCO LTD | — -28.9K (-100.0%) | — -59.7K (-100.0%) | 0.00% -0.148 pp | 0.00% -0.003 pp | USD— | 2 qtrs SOLD |
| 59 | TWO SIGMA SECURITIES, LLC | — -10.5K (-100.0%) | — -21.8K (-100.0%) | 0.00% -0.054 pp | 0.00% -0.003 pp | USD— | 2 qtrs SOLD |
| 60 | RISE ADVISORS, LLC | — -333.0 (-100.0%) | — -689.0 (-100.0%) | 0.00% -0.002 pp | 0.00% 0.000 pp | USD— | 3 qtrs SOLD |
| 61 | BOKF, NA | — -555.0 (-100.0%) | — -1.1K (-100.0%) | 0.00% -0.003 pp | 0.00% +0.000 pp | USD— | 6 qtrs SOLD |
Ownership breakdown by holder
ETF Ownership
Top ETFs holding this stock
Held by 12 ETFs in our universe
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | iShares Micro-Cap ETF IWC | 0.01% | 192.2K | 0.60% |
| 2 | Vanguard Extended Market ETF VXF | 0.00% | 475.6K | 0.05% |
| 3 | Vanguard U.S. Total Market Shares Index ETF VTS.AX | 0.00% | 5.0K | 0.03% |
| 4 | Vanguard U.S. Total Market Index ETF VUN.TO | 0.00% | 13.6K | 0.17% |
| 5 | Vanguard U.S. Total Market Index ETF (CAD-hedged) VUS.TO | 0.00% | 1.0K | 0.17% |
| 6 | Vanguard Total Stock Market ETF VTI | 0.00% | 2.33M | 0.03% |
| 7 | Vanguard All-Equity ETF Portfolio VEQT.TO | 0.00% | 5.1K | 0.22% |
| 8 | Vanguard Growth ETF Portfolio VGRO.TO | 0.00% | 2.8K | 0.22% |
| 9 | Vanguard Balanced ETF Portfolio VBAL.TO | 0.00% | 1.1K | 0.22% |
| 10 | Vanguard Conservative ETF Portfolio VCNS.TO | 0.00% | 123.70 | 0.22% |
Insider Activity
Insider Activity — Latest Quarter
Ratio by transactions
0.00
Bearish
Buys
1
Sells
0
Shares acquired
713.8K
Shares disposed
—
Cash buys
1.00
Cash sales
—
Net activity
+713,800
Insider buys vs sells (history)
From
To
Recent insider transactions
From
To
| Date | Person | Role | Transaction | A/D | Security | Shares | Price | Value | Owned after | D/I | Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-04-02 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 713,800 | 2.10 | 1.50M | 3,288,539 | D | ↗ |
| 2025-12-08 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 15,000 | 4.24 | 63.6K | 2,574,739 | D | ↗ |
| 2025-11-24 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 1,489 | 4.13 | 6.1K | 2,492,028 | D | ↗ |
| 2025-11-21 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 10,000 | 3.50 | 35.0K | 2,490,539 | D | ↗ |
| 2025-11-14 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 15,000 | 2.11 | 31.7K | 2,470,539 | D | ↗ |
| 2025-10-28 | Maccecchini Maria-Luisa | Director / Officer | P-Purchase | A | Common Stock | 97,561 | 2.05 | 200.0K | 1,212,020 | D | ↗ |
| 2025-10-28 | Hoffman Michael B | Director | P-Purchase | A | Common Stock | 975,610 | 2.05 | 2.00M | 2,455,539 | D | ↗ |
| 2025-09-10 | Bruck Claudine | Director | M-Exempt | D | Option | 7,142 | 0.14 | 999.88 | 0 | D | ↗ |
| 2025-08-29 | Hoffman Michael B | Director | A-Award | A | Common Stock | 5,000 | 2.29 | 11.5K | 1,474,929 | D | ↗ |
| 2025-08-19 | Hoffman Michael B | Director | A-Award | A | Common Stock | 1,100 | 2.57 | 2.8K | 1,464,929 | D | ↗ |
| 2025-06-16 | Walsh Andrew | Officer | A-Award | A | Common Stock | 500 | 2.90 | 1.5K | 500 | D | ↗ |
| 2025-06-13 | Hoffman Michael B | Director | A-Award | A | Common Stock | 1 | 2.83 | 2.83 | 1,446,284 | D | ↗ |
| 2025-06-10 | McCarthy Reid | Director | A-Award | A | Common Stock | 2,000 | 2.95 | 5.9K | 9,305 | D | ↗ |
| 2025-06-04 | Maccecchini Maria-Luisa | Director / Officer | A-Award | A | Common Stock | 46,000 | 3.37 | 155.0K | 1,114,459 | D | ↗ |
| 2025-05-29 | Hoffman Michael B | Director | A-Award | A | Common Stock | 5,000 | 2.43 | 12.2K | 1,421,283 | D | ↗ |
| 2025-05-09 | Walsh Andrew | Officer | — | — | Option (Right to Buy) | 10,000 | 6.07 | 60.7K | 0 | D | ↗ |
| 2024-07-01 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 5.27 | 105.4K | 20,000 | — | ↗ |
| 2024-03-31 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | G-Gift | D | Common Stock | 10,000 | 0.00 | — | 1,068,459 | — | ↗ |
| 2024-03-28 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | G-Gift | D | Common Stock | 10,000 | 0.00 | — | 1,088,459 | — | ↗ |
| 2023-11-27 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 2,146 | 7.39 | 15.9K | 2,146 | — | ↗ |
| 2023-11-20 | White Mark K. | Director | A-Award | A | Common Stock | 2,000 | 6.07 | 12.1K | 61,177 | — | ↗ |
| 2023-11-20 | McCarthy Reid | Director | A-Award | A | Common Stock | 824 | 6.07 | 5.0K | 8,129 | — | ↗ |
| 2023-11-20 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Common Stock | 41,186 | 6.07 | 250.0K | 1,098,675 | — | ↗ |
| 2023-11-20 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Common Stock | 163,880 | 6.10 | 999.7K | 223,357 | — | ↗ |
| 2023-11-20 | Hagopian Henry III | Officer | A-Award | A | Common Stock | 820 | 6.10 | 5.0K | 1,820 | — | ↗ |
| 2023-11-20 | Bruck Claudine | Director | J-Other | A | Common Stock | 0 | 0.00 | — | 6,567 | — | ↗ |
| 2023-11-17 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 26,200 | 6.07 | 159.0K | 26,200 | — | ↗ |
| 2023-11-17 | McCarthy Reid | Director | A-Award | A | Stock Option (right to buy) | 29,600 | 6.07 | 179.7K | 29,600 | — | ↗ |
| 2023-11-17 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Stock Option (right to buy) | 108,800 | 6.07 | 660.4K | 108,800 | — | ↗ |
| 2023-11-17 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 29,600 | 6.07 | 179.7K | 29,600 | — | ↗ |
| 2023-11-17 | Bruck Claudine | Director | A-Award | A | Stock Option (right to buy) | 26,200 | 6.07 | 159.0K | 26,200 | — | ↗ |
| 2023-04-24 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | G-Gift | D | Common Stock | 3,000 | 0.00 | — | 1,057,489 | — | ↗ |
| 2023-04-07 | White Mark K. | Director | A-Award | A | Common Stock | 3,000 | 12.61 | 37.8K | 59,177 | — | ↗ |
| 2023-04-07 | McCarthy Reid | Director | A-Award | A | Common Stock | 476 | 12.61 | 6.0K | 7,305 | — | ↗ |
| 2023-04-07 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Common Stock | 20,000 | 12.61 | 252.2K | 1,060,489 | — | ↗ |
| 2023-04-07 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Common Stock | 59,477 | 12.61 | 750.0K | 59,477 | — | ↗ |
| 2023-04-07 | Hagopian Henry III | Officer | A-Award | A | Common Stock | 1,000 | 12.61 | 12.6K | 1,000 | — | ↗ |
| 2023-04-07 | Bruck Claudine | Director | A-Award | A | Common Stock | 500 | 12.61 | 6.3K | 6,567 | — | ↗ |
| 2023-02-06 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | M-Exempt | A | Common Stock | 52,755 | 0.14 | 7.4K | 1,040,489 | — | ↗ |
| 2023-01-18 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 5,967 | 0.00 | — | 5,967 | — | ↗ |
| 2023-01-18 | McCarthy Reid | Director | A-Award | A | Stock Option (right to buy) | 5,967 | 0.00 | — | 5,967 | — | ↗ |
| 2023-01-18 | Maccecchini Maria-Luisa | Officer | A-Award | A | Stock Option (right to buy) | 21,312 | 0.00 | — | 21,312 | — | ↗ |
| 2023-01-18 | Hoffman Michael B | Director | A-Award | A | Stock Option (right to buy) | 6,820 | 0.00 | — | 6,820 | — | ↗ |
| 2023-01-18 | Hagopian Henry III | Officer | A-Award | A | Stock Option (right to buy) | 7,672 | 0.00 | — | 7,672 | — | ↗ |
| 2023-01-18 | Bruck Claudine | Director | A-Award | A | Stock Option (right to buy) | 5,967 | 0.00 | — | 5,967 | — | ↗ |
| 2022-08-29 | Hagopian Henry III | Officer | A-Award | A | Stock Option (right to buy) | 120,000 | 0.00 | — | 120,000 | — | ↗ |
| 2022-01-14 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | M-Exempt | A | Common Stock | 32,959 | 0.14 | 4.6K | 987,734 | — | ↗ |
| 2022-01-04 | Hoffman Michael B | Director / 10% Owner | F-InKind | D | Common Stock | 90 | 19.78 | 1.8K | 1,416,283 | — | ↗ |
| 2022-01-03 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 8,000 | 19.78 | 158.2K | 8,000 | — | ↗ |
| 2022-01-03 | McGroarty Jeffrey Brian | Officer | A-Award | A | Stock Option (right to buy) | 28,000 | 19.78 | 553.8K | 28,000 | — | ↗ |
| 2022-01-03 | McCarthy Reid | Director | A-Award | A | Stock Option (right to buy) | 8,000 | 19.78 | 158.2K | 8,000 | — | ↗ |
| 2022-01-03 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Stock Option (right to buy) | 19,894 | 19.78 | 393.5K | 19,894 | — | ↗ |
| 2022-01-03 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 9,000 | 19.78 | 178.0K | 9,000 | — | ↗ |
| 2022-01-03 | Bruck Claudine | Director | A-Award | A | Stock Option (right to buy) | 8,000 | 19.78 | 158.2K | 8,000 | — | ↗ |
| 2021-12-31 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2021-12-06 | McGroarty Jeffrey Brian | Officer | A-Award | A | Stock Option (right to buy) | 30,396 | 20.97 | 637.4K | 30,396 | — | ↗ |
| 2021-12-06 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Stock Option (right to buy) | 145,305 | 20.97 | 3.05M | 145,305 | — | ↗ |
| 2021-10-12 | White Mark K. | Director | P-Purchase | A | Common Stock | 5,000 | 27.40 | 137.0K | 56,177 | — | ↗ |
| 2021-10-11 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | P-Purchase | A | Common Stock | 18,000 | 27.61 | 497.0K | 976,775 | — | ↗ |
| 2021-10-11 | Bruck Claudine | Director | P-Purchase | A | Common Stock | 181 | 27.66 | 5.0K | 6,067 | — | ↗ |
| 2021-08-19 | McCarthy Reid | Director | P-Purchase | A | Common Stock, $0.0001 par value | 500 | 37.61 | 18.8K | 6,829 | — | ↗ |
| 2021-07-07 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 4,000 | 102.85 | 411.4K | 4,000 | — | ↗ |
| 2021-07-07 | McGroarty Jeffrey Brian | Officer | A-Award | A | Stock Option (right to buy) | 14,000 | 102.85 | 1.44M | 14,000 | — | ↗ |
| 2021-07-07 | McCarthy Reid | Director | A-Award | A | Stock Option (right to buy) | 4,000 | 102.85 | 411.4K | 4,000 | — | ↗ |
| 2021-07-07 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Stock Option (right to buy) | 41,700 | 102.85 | 4.29M | 41,700 | — | ↗ |
| 2021-07-07 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 4,500 | 102.85 | 462.8K | 4,500 | — | ↗ |
| 2021-07-07 | Bruck Claudine | Director | A-Award | A | Stock Option (right to buy) | 4,000 | 102.85 | 411.4K | 4,000 | — | ↗ |
| 2021-04-09 | McCarthy Reid | Director | — | D | Common Stock, $0.0001 par value | 0 | 0.00 | — | 6,329 | — | ↗ |
| 2020-07-01 | White Mark K. | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 4.39 | 87.8K | 20,000 | — | ↗ |
| 2020-07-01 | Whelan, Jr. Robert M. | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 4.39 | 87.8K | 20,000 | — | ↗ |
| 2020-07-01 | Hoffman Michael B | Director / 10% Owner | A-Award | A | Stock Option (right to buy) | 30,000 | 4.39 | 131.7K | 30,000 | — | ↗ |
| 2020-07-01 | Bruck Claudine | Director | A-Award | A | Stock Option (right to buy) | 20,000 | 4.39 | 87.8K | 20,000 | — | ↗ |
| 2020-04-09 | McGroarty Jeffrey Brian | Officer | A-Award | A | Stock Option (right to buy) | 300,000 | 3.13 | 939.0K | 300,000 | — | ↗ |
| 2020-04-09 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | A-Award | A | Stock Option (right to buy) | 300,000 | 3.13 | 939.0K | 300,000 | — | ↗ |
| 2020-02-03 | McGroarty Jeffrey Brian | Officer | P-Purchase | A | Common Stock | 19,336 | 7.15 | 138.3K | 52,669 | — | ↗ |
| 2020-01-31 | White Mark K. | Director | C-Conversion | D | Series A Preferred Stock | 48,500 | 0.00 | — | 0 | — | ↗ |
| 2020-01-31 | Whelan, Jr. Robert M. | Director | C-Conversion | A | Common Stock | 11,176 | 4.80 | 53.6K | 95,700 | — | ↗ |
| 2020-01-31 | McGroarty Jeffrey Brian | Officer | P-Purchase | A | Common Stock | 33,333 | 6.00 | 200.0K | 33,333 | — | ↗ |
| 2020-01-31 | Maccecchini Maria-Luisa | Director / Officer / 10% Owner | C-Conversion | A | Common Stock | 7,937 | 0.00 | — | 215,879 | — | ↗ |
| 2020-01-31 | Hoffman Michael B | Director / 10% Owner | C-Conversion | D | Convertible Note | 55,884 | 0.00 | — | 0 | — | ↗ |
| 2020-01-31 | Bruck Claudine | Director | C-Conversion | D | Convertible Note | 1,117 | 0.00 | — | 0 | — | ↗ |
| 2020-01-28 | White Mark K. | Director | — | D | Convertible Note | 0 | 0.00 | — | 0 | — | ↗ |
| 2020-01-28 | Whelan, Jr. Robert M. | Director | — | D | Series A-1 Preferred Stock | 59,524 | 0.00 | — | 0 | — | ↗ |
| 2020-01-28 | McGroarty Jeffrey Brian | Officer | — | — | — | 0 | 0.00 | — | 0 | — | ↗ |
| 2020-01-28 | Maccecchini Maria-Luisa | Director / Officer | — | D | Common Stock, $0.0001 par value | 0 | 0.00 | — | 206,342 | — | ↗ |
| 2020-01-28 | Hoffman Michael B | Director | — | D | Convertible Note | 0 | 0.00 | — | 0 | — | ↗ |
| 2020-01-28 | Bruck Claudine | Director | — | D | Series A-1 Preferred Stock | 5,556 | 0.00 | — | 0 | — | ↗ |
Executive team
Top executives
Shares Outstanding
19.67M
Executive compensation
Executive compensation (annual)
| # | Year | Executive | Salary | Bonus | Stock award | Option award | Incentive | Other | Total | % Stock- based |
Filing |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2025 | Maria Maccecchini President and Chief Executive Officer and Acting CFO | 808.0K | — | — | — | — | — | 808.0K | 0.00% | ↗ |
| 2 | 2025 | Mark Guerin | 112.5K | — | — | 122.0K | — | — | 234.5K | 52.03% | ↗ |
| 3 | 2024 | Maria Maccecchini President and Chief Executive Officer and Acting CFO | 734.8K | — | — | 1.58M | — | 13.8K | 2.33M | 67.84% | ↗ |
| 4 | 2024 | Maria Maccecchini President and Chief Executive Officer | 734.8K | — | — | 1.58M | — | 13.8K | 2.33M | 67.84% | ↗ |
| 5 | 2023 | Maria Maccecchini President and Chief Executive Officer | 668.0K | — | — | 2.11M | — | 13.2K | 2.79M | 75.57% | ↗ |
| 6 | 2023 | Henry Hagopian III Chief Financial Officer (post August 29, 2022) | 375.0K | — | — | 115.9K | — | — | 490.9K | 23.61% | ↗ |
| 7 | 2022 | Maria Maccecchini President and Chief Executive Officer | 636.0K | 318.0K | — | 1.69M | — | 11.6K | 2.65M | 63.62% | ↗ |
| 8 | 2022 | Henry Hagopian III Chief Financial Officer | 129.3K | — | — | 1.16M | 131.3K | — | 1.42M | 81.61% | ↗ |
| 9 | 2022 | Henry Hagopian III Chief Financial Officer (post August 29, 2022) | 129.3K | 131.3K | — | 1.16M | — | — | 1.42M | 81.61% | ↗ |
| 10 | 2022 | Jeffrey McGroarty Former Chief Financial Officer | 330.3K | — | — | 622.4K | — | 11.6K | 964.3K | 64.55% | ↗ |
| 11 | 2021 | Maria Maccecchini President and Chief Executive Officer | 510.0K | — | — | 7.79M | 270.0K | 11.6K | 8.59M | 90.78% | ↗ |
| 12 | 2021 | Jeffrey McGroarty Former Chief Financial Officer | 315.0K | — | — | 4.50M | 148.5K | 11.6K | 4.98M | 90.46% | ↗ |
| 13 | 2021 | Jeffrey McGroarty Chief Financial Officer | 315.0K | — | — | 4.50M | 148.5K | 11.6K | 4.98M | 90.46% | ↗ |
| 14 | 2020 | Maria Maccecchini President and Chief Executive Officer | 420.0K | — | — | 594.2K | 210.0K | — | 1.22M | 48.54% | ↗ |
| 15 | 2020 | Jeffrey McGroarty Chief Financial Officer | 300.0K | — | — | 594.2K | 150.0K | — | 1.04M | 56.91% | ↗ |
| 16 | 2019 | Maria Maccecchini President and Chief Executive Officer | 120.0K | — | — | — | — | — | 120.0K | 0.00% | ↗ |
| 17 | 2018 | Maria Maccecchini President and Chief Executive Officer | 120.0K | — | — | 35.2K | — | — | 155.2K | 22.66% | ↗ |
CEO compensation breakdown
Proxy statements
Proxy statements (DEF 14A)
Recent SEC filings
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Maria L. Maccecchini | Founder, Acting CFO, CEO, President & Executive Director | 748.6K | — |
| Mark Patrick Guerin | Chief Financial Officer | 375.0K | male |
| Eve Damiano | Senior Vice President of Regulatory Operations | — | female |
| Blake Jensen | Head of Quality | — | male |
| Melissa Gaines | Senior Vice President of Clinical Operations | — | female |
| Hilda Maibach | Senior Vice President of Statistics | — | female |
| Cheng Fang | Senior Vice President of Research & Development | — | — |
ESG Rating
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity
No Senate trading activity found for this company.
House Trading Activity
No House trading activity found for this company.
Market share among peers
Peer comparison — filtered group (TTM)
Your opinion
Share your view on this stock and instantly see how the community has voted over the last 6 months.
Community Opinion for ANVS
Short-term intention
Target Price Distribution
These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.
