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Alumis Inc. (ALMS)

USD28.10 -0.21 (-0.74%)
US NASDAQ Healthcare Biotechnology
Address 280 East Grand Avenue 94080
South San Francisco, CA, US
CEO Martin Babler
Website alumis.com
IPO 2024-06-28
CIK 1847367 ISIN US0223071020

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Description

Alumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disorders. The company offers envudeucitinib, a tyrosine kinase 2 (TYK2) inhibitor for the treatment of plaque psoriasis and systemic lupus erythematosus; and A-005, a central nervous system-penetrant allosteric TYK2 inhibitor that is in Phase 1 for the treatment of neuroinflammatory and neurodegenerative diseases. It also develops lonigutamab, a monoclonal antibody targeting IGF-1R for the treatment of thyroid eye diseases; and interferon regulatory factor 5 (IRF5) to address immune dysfunction. The company was formerly known as Esker Therapeutics, Inc. and changed its name to Alumis Inc. in January 2022. Alumis Inc. was incorporated in 2021 and is headquartered in South San Francisco, California.

Market Cap & Enterprise Value
Merger & Acquisition History
Target company Ticker Date Filing
Acelyrin, Inc. SLRN 2025-03-27 View
Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD28.10 -0.21 (-0.74%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
-0.54
Float Shares
82.71M
Free Float %
67.2%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.93% +2.84% +7.60% -7.20% +346.20% +152.36% +446.12% +85.19% +85.19% +85.19% +85.19%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (8 ratings, all time) Buy
Price Targets & DCF
Current price
28.10
Low 32.00 +13.9%
Consensus 38.44 +36.8%
Median 37.00 +31.7%
High 50.00 +77.9%
DCF (Unlevered) 1.13 -96.0%
DCF (Levered) 0.49 -98.3%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 10 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month
Last Quarter 1
46.00
+63.7%
Last Year 10
36.60
+30.2%
All Time 13
33.38
+18.8%
Quality scores
Altman Z-Score
14.13
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
2 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    Q1'26: -90.0% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +72.5% Q1'26: +59.3% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -1,619.5% Q1'26: -5,011.3% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -1,776.3% Q1'26: +0.0% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -1,437.9% Q1'26: +0.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +2,900.1% Q1'26: +130.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.09× Q1'26: -0.09× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.29) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 1.13 Current price: 28.10
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2024
actual
Dec 2025
actual
Dec 2026
8 Rev. Ana.
7 EPS Ana.
Dec 2027
8 Rev. Ana.
6 EPS Ana.
Dec 2028
8 Rev. Ana.
7 EPS Ana.
Dec 2029
7 Rev. Ana.
2 EPS Ana.
Dec 2030
7 Rev. Ana.
5 EPS Ana.
Revenue
est: 17.39M (-100.0%)
24.05M
est: 24.26M (-0.9%)
8.17M
6.23M – 10.38M
-66.3% YoY
30.06M
16.19M – 42.02M
+267.9% YoY
169.24M
167.33M – 171.14M
+462.9% YoY
426.59M
252.50M – 583.33M
+152.1% YoY
875.79M
518.37M – 1.20B
+105.3% YoY
EBITDA
-297.60M
est: 8.69M (-3,522.9%)
-423.71M
est: 12.13M (-3,592.4%)
4.09M
3.11M – 5.19M
-66.3% YoY
15.03M
8.09M – 21.01M
+267.9% YoY
84.62M
83.67M – 85.57M
+462.9% YoY
213.30M
126.25M – 291.67M
+152.1% YoY
437.89M
259.19M – 598.79M
+105.3% YoY
EBIT
-300.75M
est: 8.69M (-3,559.1%)
-427.20M
est: 12.13M (-3,621.2%)
4.09M
3.11M – 5.19M
-66.3% YoY
15.03M
8.09M – 21.01M
+267.9% YoY
84.62M
83.67M – 85.57M
+462.9% YoY
213.30M
126.25M – 291.67M
+152.1% YoY
437.89M
259.19M – 598.79M
+105.3% YoY
Net Income
-294.23M
est: -5.39B (+94.5%)
-243.33M
est: -2.43B (+90.0%)
-2.67B
-3.08B – -2.25B
-9.9% YoY
-2.59B
-3.05B – -2.14B
+2.8% YoY
-1.64B
-2.39B – -884.31M
+36.9% YoY
-751.66M
-1.11B – -352.88M
+54.1% YoY
1.10B
517.35M – 1.63B
+246.6% YoY
SGA
35.20M
est: 29.65M (+18.7%)
91.86M
est: 41.37M (+122.0%)
13.93M
10.62M – 17.70M
-66.3% YoY
51.25M
27.59M – 71.64M
+267.9% YoY
288.52M
285.28M – 291.77M
+462.9% YoY
727.27M
430.47M – 994.49M
+152.1% YoY
1.49B
883.75M – 2.04B
+105.3% YoY
EPS
-10.38
est: -6.66 (-56.0%)
-2.86
est: -2.86 (+0.1%)
-2.94
-3.63 – -2.65
-2.5% YoY
-2.88
-3.58 – -2.51
+1.9% YoY
-1.92
-2.81 – -1.04
+33.2% YoY
-0.88
-1.31 – -0.42
+54.0% YoY
1.30
0.61 – 1.92
+246.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-14 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-13 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-12 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-11 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-08 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 2/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-30 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-29 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-28 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-27 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C- 1/5 2/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-15 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-157.82M
OE per share TTM
-1.26
Owner's Yield
-5.12%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
451.0%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
47
Total invested
125.89M
Insider transactions (90d)
0
Beneficial owners (>5%)
21
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 B. Tananbaum (“Tananbaum”) 15.15M 29.20% 13.98M 1.18M 13.98M 1.18M IN OR PLACE OF ORGANIZATION       U.S. Citizen 2024-07-05
2 AyurMaya Capital Management Company, LP 10.65M 22.57% 10.65M 10.00 IA, PN State of Delaware 2024-07-03
3 David E. Goel 10.65M 22.57% 10.65M 10.00 HC, IN United States of America 2024-07-03
4 Capital Management V, LLC (“FCM V”) 5.78M 11.10% 5.78M 5.78M OO 2024-07-05
5 Capital Fund V, L.P. (“Fund V”) 5.58M 10.80% 5.58M 5.58M PN 2024-07-05
6 Capital Fund VI, L.P. (“Fund VI”) 4.20M 8.10% 4.20M 4.20M PN 2024-07-05
7 Capital Management VI, LLC (“FCM VI”) 4.20M 8.10% 4.20M 4.20M OO 2024-07-05
8 Samsara BioCapital GP, LLC 3.27M 6.90% 3.27M 10.00 OO Delaware 2024-08-27
9 Samsara BioCapital, L.P. 3.27M 6.90% 3.27M 10.00 PN Delaware 2024-08-27
10 Srinivas Akkaraju 3.27M 6.90% 3.27M 11.00 IN 2024-08-27
11 Corey Goodman 2.83M 6.30% 2.83M 2.83M HC, IN Delaware 2024-07-11
12 Robert Adelman 2.83M 6.30% 2.83M 2.83M HC, IN Delaware 2024-07-11
13 venBio Global Strategic Fund IV, L.P. 2.83M 6.30% 2.83M 2.83M PN Delaware 2024-07-11
14 venBio Global Strategic GP IV, LLC 2.83M 6.30% 2.83M 2.83M HC, OO Delaware 2024-07-11
15 Capital Opportunity Fund V, L.P. (“Opportunity Fund V”) 2.03M 3.90% 2.03M 2.03M PN 2024-07-05
16 Capital Opportunity Management V, LLC (“FCOM V”) 2.03M 3.90% 2.03M 2.03M OO 2024-07-05
17 Labs Fund I, L.P. (“Labs Fund I”) 1.96M 3.80% 1.96M 1.96M PN OR PLACE OF ORGANIZATION       Delaware 2024-07-05
18 Labs Management I, LLC (“FLM I”) 1.96M 3.80% 1.96M 1.96M OO 2024-07-05
19 Labs Affiliates 2021, LLC (“Labs Affiliates”) 1.18M 2.30% 1.18M 1.18M OO OR PLACE OF ORGANIZATION       Delaware 2024-07-05
20 Labs, LLC (“Labs”) 1.18M 2.30% 1.18M 1.18M OO OR PLACE OF ORGANIZATION       Delaware 2024-07-05
21 Co-Invest V, LLC (“Labs Co-Invest”) 194.5K 0.40% 194.5K 194.5K OO 2024-07-05

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
47
-94 vs prev Q
New positions
16
Closed positions
104
Increased
35
Reduced
6
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 43.8K +43.8K (+100.0%) 427.19M +427.2M (+100.0%) 0.04% +0.042 pp 0.37% +0.373 pp USD9.76 +0.0% 1 qtrs NEW
2 AYURMAYA CAPITAL MANAGEMENT COMPANY, LP 15.14M +— (+0.0%) 147.76M +87.4M (+144.6%) 14.54% +0.000 pp 100.00% +0.000 pp USD9.71 +0.5% 7 qtrs
3 FORESITE CAPITAL MANAGEMENT V, LLC 5.78M +— (+0.0%) 56.41M +33.3M (+144.6%) 5.55% +0.000 pp 34.31% +13.104 pp USD12.38 -21.2% 7 qtrs
4 SAMSARA BIOCAPITAL, LLC 5.76M +955.6K (+19.9%) 56.19M +37.0M (+193.3%) 5.53% +0.918 pp 5.80% +3.296 pp USD8.48 +15.1% 6 qtrs
5 VENBIO PARTNERS LLC 4.62M +— (+0.0%) 45.09M +26.7M (+144.6%) 4.44% +0.000 pp 20.85% +10.399 pp USD8.76 +11.4% 7 qtrs
6 BLACKROCK, INC. 4.57M +373.4K (+8.9%) 44.57M +27.8M (+166.4%) 4.39% +0.359 pp 0.00% +0.001 pp USD5.50 +77.5% 6 qtrs
7 FORESITE CAPITAL MANAGEMENT VI LLC 4.25M +— (+0.0%) 41.46M +24.5M (+144.6%) 4.08% +0.000 pp 12.53% +5.984 pp USD7.81 +25.0% 5 qtrs
8 VANGUARD GROUP INC 4.10M +73.7K (+1.8%) 40.05M +24.0M (+149.1%) 3.94% +0.071 pp 0.00% +0.000 pp USD4.96 +96.8% 7 qtrs
9 CORMORANT ASSET MANAGEMENT, LP 3.64M +1.5M (+69.3%) 35.48M +26.9M (+314.1%) 3.49% +1.430 pp 1.64% +1.050 pp USD11.40 -14.4% 7 qtrs
10 SATURN V CAPITAL MANAGEMENT LLC 3.14M +3.1M (+100.0%) 30.61M +30.6M (+100.0%) 3.01% +3.012 pp 5.62% +5.617 pp USD9.76 +0.0% 1 qtrs NEW
11 NEXTECH INVEST, LTD. 2.92M +— (+0.0%) 28.46M +16.8M (+144.6%) 2.80% +0.000 pp 2.75% +0.980 pp USD4.59 +112.6% 4 qtrs
12 OCTAGON CAPITAL ADVISORS LP 2.53M +2.5M (+100.0%) 24.70M +24.7M (+100.0%) 2.43% +2.431 pp 3.00% +2.999 pp USD9.76 +0.0% 1 qtrs NEW
13 BIOIMPACT CAPITAL LLC 2.40M +2.4M (+100.0%) 23.44M +23.4M (+100.0%) 2.31% +2.307 pp 2.68% +2.683 pp USD9.76 +0.0% 1 qtrs NEW
14 SR ONE CAPITAL MANAGEMENT, LP 1.96M +— (+0.0%) 19.13M +11.3M (+144.6%) 1.88% +0.000 pp 2.71% +1.577 pp USD12.54 -22.2% 7 qtrs
15 BAKER BROS. ADVISORS LP 1.56M +— (+0.0%) 15.25M +9.0M (+144.6%) 1.50% +0.000 pp 0.09% +0.044 pp USD12.54 -22.2% 7 qtrs
16 GEODE CAPITAL MANAGEMENT, LLC 1.49M +94.3K (+6.8%) 14.52M +9.0M (+161.2%) 1.43% +0.091 pp 0.00% +0.001 pp USD5.46 +78.8% 6 qtrs
17 STATE STREET CORP 1.26M +157.6K (+14.3%) 12.29M +7.9M (+179.6%) 1.21% +0.151 pp 0.00% +0.000 pp USD4.77 +104.6% 6 qtrs
18 MILLENNIUM MANAGEMENT LLC 1.15M +834.1K (+263.1%) 11.23M +10.0M (+788.2%) 1.11% +0.801 pp 0.00% +0.004 pp USD7.90 +23.5% 3 qtrs
19 ORBIMED ADVISORS LLC 1.10M -823.7K (-42.8%) 10.76M +3.1M (+40.0%) 1.06% -0.791 pp 0.22% +0.039 pp USD3.00 +225.3% 3 qtrs
20 TRIUM CAPITAL LLP 893.1K -2.2M (-71.4%) 8.72M -3.7M (-30.0%) 0.86% -2.141 pp 6.76% +1.893 pp USD3.15 +209.8% 3 qtrs
21 YU FAN 789.6K +— (+0.0%) 7.71M +4.6M (+144.6%) 0.76% +0.000 pp 8.35% +4.253 pp USD12.54 -22.2% 7 qtrs
22 OMEGA FUND MANAGEMENT, LLC 653.2K +— (+0.0%) 6.38M +3.8M (+144.6%) 0.63% +0.000 pp 2.23% +1.053 pp USD12.54 -22.2% 7 qtrs
23 OPALEYE MANAGEMENT INC. 535.0K -130.0K (-19.5%) 5.22M +2.6M (+96.8%) 0.51% -0.125 pp 0.69% +0.314 pp USD3.00 +225.3% 3 qtrs
24 MORGAN STANLEY 506.5K +174.1K (+52.4%) 4.94M +3.6M (+272.7%) 0.49% +0.167 pp 0.00% +0.000 pp USD7.22 +35.2% 7 qtrs
25 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 504.1K +13.1K (+2.7%) 4.92M +3.0M (+151.1%) 0.48% +0.013 pp 0.00% +0.001 pp USD5.19 +88.1% 6 qtrs
26 SIREN, L.L.C. 500.0K +500.0K (+100.0%) 4.88M +4.9M (+100.0%) 0.48% +0.480 pp 0.15% +0.146 pp USD9.76 +0.0% 1 qtrs NEW
27 TOWERVIEW LLC 495.0K +— (+0.0%) 4.83M +2.9M (+144.6%) 0.48% +0.000 pp 3.50% +2.064 pp USD10.50 -7.0% 7 qtrs
28 GOLDMAN SACHS GROUP INC 427.1K +10.0K (+2.4%) 4.17M +2.5M (+150.5%) 0.41% +0.010 pp 0.00% +0.000 pp USD4.68 +108.5% 6 qtrs
29 INVESCO LTD. 421.8K +292.3K (+225.6%) 4.12M +3.6M (+696.4%) 0.41% +0.281 pp 0.00% +0.001 pp USD7.94 +22.9% 4 qtrs
30 NORTHERN TRUST CORP 418.2K -20.7K (-4.7%) 4.08M +2.3M (+133.1%) 0.40% -0.020 pp 0.00% +0.000 pp USD5.37 +81.8% 6 qtrs
31 MARSHALL WACE, LLP 372.9K +372.9K (+100.0%) 3.64M +3.6M (+100.0%) 0.36% +0.358 pp 0.00% +0.003 pp USD9.76 +0.0% 1 qtrs NEW
32 JPMORGAN CHASE & CO 356.3K +87.7K (+32.6%) 3.48M +2.4M (+224.4%) 0.34% -0.009 pp 0.00% +0.000 pp USD4.92 +98.4% 6 qtrs
33 TWO SIGMA INVESTMENTS, LP 298.2K +212.1K (+246.4%) 2.91M +2.6M (+747.4%) 0.29% +0.204 pp 0.00% +0.004 pp USD8.09 +20.6% 4 qtrs
34 EXOME ASSET MANAGEMENT LLC 292.3K -520.0 (-0.2%) 2.85M +1.7M (+144.2%) 0.28% -0.001 pp 1.36% +0.657 pp USD3.99 +144.6% 2 qtrs
35 D. E. SHAW & CO., INC. 231.7K +231.7K (+100.0%) 2.26M +2.3M (+100.0%) 0.22% +0.223 pp 0.00% +0.001 pp USD9.76 +0.0% 1 qtrs NEW
36 IKARIAN CAPITAL, LLC 211.1K +211.1K (+100.0%) 2.06M +2.1M (+100.0%) 0.20% +0.203 pp 0.16% +0.161 pp USD9.76 +0.0% 1 qtrs NEW
37 STIFEL FINANCIAL CORP 209.7K +— (+0.0%) 2.05M +1.2M (+144.6%) 0.20% +0.000 pp 0.00% +0.001 pp USD6.71 +45.5% 6 qtrs
38 SUSQUEHANNA INTERNATIONAL GROUP, LLP 208.1K -154.5K (-42.6%) 2.03M +584.4K (+40.4%) 0.20% -0.148 pp 0.00% +0.000 pp USD3.14 +210.8% 4 qtrs
39 JANE STREET GROUP, LLC 173.8K +146.7K (+541.2%) 1.70M +1.6M (+1,468.5%) 0.17% +0.141 pp 0.00% +0.000 pp USD8.79 +11.0% 4 qtrs
40 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 172.8K +14.0K (+8.8%) 1.69M +1.1M (+166.2%) 0.17% +0.014 pp 0.03% +0.016 pp USD4.46 +118.8% 2 qtrs
41 NUVEEN, LLC 169.5K +68.8K (+68.3%) 1.65M +1.3M (+311.6%) 0.16% +0.066 pp 0.00% +0.000 pp USD6.00 +62.7% 4 qtrs
42 WELLINGTON MANAGEMENT GROUP LLP 169.1K +3.6K (+2.2%) 1.65M +990.0K (+149.9%) 0.16% +0.003 pp 0.00% +0.000 pp USD4.11 +137.5% 2 qtrs
43 BANK OF NEW YORK MELLON CORP 160.1K +23.4K (+17.1%) 1.56M +1.0M (+186.5%) 0.15% +0.023 pp 0.00% +0.000 pp USD5.78 +68.9% 6 qtrs
44 MARINER, LLC 145.0K +60.2K (+70.9%) 1.42M +1.1M (+318.1%) 0.14% +0.058 pp 0.00% +0.001 pp USD6.17 +58.2% 5 qtrs
45 BANK OF AMERICA CORP /DE/ 138.3K -125.6K (-47.6%) 1.35M +297.2K (+28.2%) 0.13% -0.212 pp 0.00% +0.000 pp USD4.30 +127.0% 6 qtrs
46 AQR CAPITAL MANAGEMENT LLC 137.8K -3.1K (-2.2%) 1.34M +782.6K (+139.2%) 0.13% -0.003 pp 0.00% +0.000 pp USD3.81 +156.2% 3 qtrs
47 QUANTINNO CAPITAL MANAGEMENT LP 135.4K +47.8K (+54.6%) 1.32M +972.4K (+278.2%) 0.13% +0.046 pp 0.00% +0.002 pp USD6.03 +61.9% 2 qtrs
48 WELLS FARGO & COMPANY/MN 129.4K +40.2K (+45.0%) 1.26M +907.2K (+254.7%) 0.12% +0.039 pp 0.00% +0.000 pp USD6.00 +62.7% 6 qtrs
49 BARCLAYS PLC 122.2K +103.9K (+565.6%) 1.19M +996.7K (+508.3%) 0.12% +0.093 pp 0.00% +0.000 pp USD9.04 +8.0% 6 qtrs
50 CITADEL ADVISORS LLC 119.3K -219.9K (-64.8%) 1.16M -189.1K (-14.0%) 0.11% -0.211 pp 0.00% +0.000 pp USD3.68 +165.2% 7 qtrs
51 UBS GROUP AG 114.0K -648.7K (-85.1%) 1.11M -1.9M (-63.4%) 0.11% -0.623 pp 0.00% 0.000 pp USD3.34 +192.2% 6 qtrs
52 RENAISSANCE TECHNOLOGIES LLC 108.2K -43.4K (-28.6%) 1.06M +451.3K (+74.6%) 0.10% -0.042 pp 0.00% +0.001 pp USD3.00 +225.3% 3 qtrs
53 PRELUDE CAPITAL MANAGEMENT, LLC 87.8K +— (+0.0%) 857.2K +506.8K (+144.6%) 0.08% +0.000 pp 0.06% +0.036 pp USD4.24 +130.2% 4 qtrs
54 VERITION FUND MANAGEMENT LLC 80.1K +80.1K (+100.0%) 781.4K +781.4K (+100.0%) 0.08% +0.077 pp 0.00% +0.003 pp USD9.76 +0.0% 1 qtrs NEW
55 LOS ANGELES CAPITAL MANAGEMENT LLC 163.1K +40.4K (+32.9%) 760.0K +270.4K (+55.2%) 0.16% +0.039 pp 0.00% +0.001 pp USD4.67 +109.0% 3 qtrs
56 ALLIANCEBERNSTEIN L.P. 76.6K -4.3K (-5.3%) 747.6K +424.8K (+131.6%) 0.07% -0.004 pp 0.00% +0.000 pp USD3.00 +225.3% 3 qtrs
57 RHUMBLINE ADVISERS 69.2K -4.8K (-6.5%) 675.7K +380.4K (+128.8%) 0.07% -0.005 pp 0.00% +0.000 pp USD4.58 +113.1% 6 qtrs
58 BOOTHBAY FUND MANAGEMENT, LLC 58.0K +58.0K (+100.0%) 566.1K +566.1K (+100.0%) 0.06% +0.056 pp 0.01% +0.008 pp USD9.76 +0.0% 1 qtrs NEW
59 BRIDGEWAY CAPITAL MANAGEMENT, LLC 56.7K -17.0K (-23.1%) 553.7K +259.5K (+88.2%) 0.05% -0.016 pp 0.01% +0.005 pp USD3.00 +225.3% 3 qtrs
60 PRICE T ROWE ASSOCIATES INC /MD/ 50.4K +22.1K (+78.3%) 493.0K +380.0K (+336.3%) 0.05% +0.021 pp 0.00% +0.000 pp USD5.97 +63.5% 3 qtrs
61 VIRTU FINANCIAL LLC 50.3K +50.3K (+100.0%) 491.0K +491.0K (+100.0%) 0.05% +0.048 pp 0.02% +0.019 pp USD9.76 +0.0% 1 qtrs NEW
62 BNP PARIBAS ARBITRAGE, SNC 46.9K +35.1K (+298.3%) 457.6K +410.6K (+874.4%) 0.05% +0.034 pp 0.00% +0.000 pp USD8.73 +11.8% 6 qtrs
63 DEUTSCHE BANK AG\ 41.1K +16.4K (+66.2%) 401.3K +302.6K (+306.6%) 0.04% +0.016 pp 0.00% +0.000 pp USD5.75 +69.7% 4 qtrs
64 LMR PARTNERS LLP 40.0K -218.4K (-84.5%) 390.4K -640.8K (-62.1%) 0.04% -0.210 pp 0.00% -0.004 pp USD3.10 +214.8% 3 qtrs
65 CREATIVE PLANNING 38.1K +38.1K (+100.0%) 372.0K +372.0K (+100.0%) 0.04% +0.037 pp 0.00% +0.000 pp USD9.76 +0.0% 1 qtrs NEW
66 TWO SIGMA ADVISERS, LP 38.1K +4.6K (+13.7%) 371.6K +238.0K (+178.2%) 0.04% +0.004 pp 0.00% +0.001 pp USD4.69 +108.1% 2 qtrs
67 FOX RUN MANAGEMENT, L.L.C. 37.7K +37.7K (+100.0%) 368.0K +368.0K (+100.0%) 0.04% +0.036 pp 0.06% +0.057 pp USD9.76 +0.0% 1 qtrs NEW
68 BREVAN HOWARD CAPITAL MANAGEMENT LP 34.9K +34.9K (+100.0%) 340.8K +340.8K (+100.0%) 0.03% +0.034 pp 0.00% +0.004 pp USD9.76 +0.0% 1 qtrs NEW
69 METLIFE INVESTMENT MANAGEMENT, LLC 32.5K -110.0 (-0.3%) 317.0K +187.0K (+143.8%) 0.03% 0.000 pp 0.00% +0.001 pp USD3.99 +144.6% 2 qtrs
70 GRANGE CAPITAL, LLC 32.0K +32.0K (+100.0%) 312.3K +312.3K (+100.0%) 0.03% +0.031 pp 0.30% +0.300 pp USD9.76 +0.0% 1 qtrs NEW
71 GSA CAPITAL PARTNERS LLP 30.9K +30.9K (+100.0%) 302.0K +302.0K (+100.0%) 0.03% +0.030 pp 0.03% +0.026 pp USD9.76 +0.0% 1 qtrs NEW
72 INTECH INVESTMENT MANAGEMENT LLC 29.3K +5.8K (+24.5%) 286.0K +192.0K (+204.4%) 0.03% +0.006 pp 0.00% +0.002 pp USD4.33 +125.4% 3 qtrs
73 INSCRIPTION CAPITAL, LLC 26.7K +6.2K (+30.5%) 260.3K +178.7K (+219.2%) 0.03% +0.006 pp 0.03% +0.018 pp USD5.34 +82.8% 2 qtrs
74 DYNAMIC TECHNOLOGY LAB PRIVATE LTD 26.6K +26.6K (+100.0%) 259.0K +259.0K (+100.0%) 0.03% +0.026 pp 0.06% +0.059 pp USD9.76 +0.0% 1 qtrs NEW
75 AXQ CAPITAL, LP 26.4K +7.0K (+35.8%) 257.8K +180.2K (+232.2%) 0.03% +0.007 pp 0.06% +0.028 pp USD5.51 +77.1% 2 qtrs
76 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 26.2K +269.0 (+1.0%) 256.1K +152.5K (+147.1%) 0.03% +0.000 pp 0.00% +0.000 pp USD5.80 +68.3% 6 qtrs
77 XTX TOPCO LTD 25.0K +343.0 (+1.4%) 243.6K +145.4K (+148.0%) 0.02% +0.000 pp 0.01% +0.001 pp USD4.07 +139.8% 5 qtrs
78 BALYASNY ASSET MANAGEMENT L.P. 24.8K +24.8K (+100.0%) 241.7K +241.7K (+100.0%) 0.02% +0.024 pp 0.00% +0.000 pp USD9.76 +0.0% 3 qtrs
79 FMR LLC 24.0K +17.1K (+246.1%) 234.1K +206.5K (+746.5%) 0.02% +0.016 pp 0.00% +0.000 pp USD8.17 +19.5% 6 qtrs
80 VIRTUS INVESTMENT ADVISERS, INC. 23.2K +23.2K (+100.0%) 226.0K +226.0K (+100.0%) 0.02% +0.022 pp 0.06% +0.061 pp USD9.76 +0.0% 1 qtrs NEW
81 SCHONFELD STRATEGIC ADVISORS LLC 23.0K +23.0K (+100.0%) 224.8K +224.8K (+100.0%) 0.02% +0.022 pp 0.00% +0.001 pp USD9.76 +0.0% 1 qtrs NEW
82 BANK OF NOVA SCOTIA 20.9K +20.9K (+100.0%) 204.0K +204.0K (+100.0%) 0.02% +0.020 pp 0.00% +0.000 pp USD9.76 +0.0% 1 qtrs NEW
83 DIMENSIONAL FUND ADVISORS LP 20.5K +— (+0.0%) 200.2K +118.4K (+144.6%) 0.02% +0.000 pp 0.00% +0.000 pp USD3.00 +225.3% 3 qtrs
84 MANUFACTURERS LIFE INSURANCE COMPANY, THE 17.7K +318.0 (+1.8%) 172.4K +103.2K (+149.1%) 0.02% +0.000 pp 0.00% +0.000 pp USD3.12 +212.8% 3 qtrs
85 IEQ CAPITAL, LLC 17.4K +690.0 (+4.1%) 170.0K +103.3K (+154.7%) 0.02% +0.001 pp 0.00% +0.000 pp USD4.22 +131.3% 2 qtrs
86 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 15.8K -1.1K (-6.7%) 154.6K +86.8K (+128.2%) 0.02% -0.001 pp 0.01% +0.006 pp USD5.40 +80.7% 5 qtrs
87 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 15.3K +— (+0.0%) 149.7K +88.5K (+144.6%) 0.01% +0.000 pp 0.00% +0.001 pp USD4.43 +120.3% 5 qtrs
88 RUSSELL INVESTMENTS GROUP, LTD. 15.0K +8.6K (+134.1%) 146.7K +121.1K (+472.7%) 0.01% +0.008 pp 0.00% +0.000 pp USD7.20 +35.6% 3 qtrs
89 MERCER GLOBAL ADVISORS INC /ADV 14.9K +14.9K (+100.0%) 145.5K +145.5K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD9.76 +0.0% 1 qtrs NEW
90 PROSHARE ADVISORS LLC 14.6K +1.6K (+12.4%) 142.8K +90.9K (+175.0%) 0.01% +0.002 pp 0.00% +0.000 pp USD3.75 +160.3% 3 qtrs
91 PDT PARTNERS, LLC 14.6K +14.6K (+100.0%) 142.1K +142.1K (+100.0%) 0.01% +0.014 pp 0.01% +0.009 pp USD9.76 +0.0% 1 qtrs NEW
92 BANCO BTG PACTUAL S.A. 14.3K +14.3K (+100.0%) 139.6K +139.6K (+100.0%) 0.01% +0.014 pp 0.02% +0.024 pp USD9.76 +0.0% 1 qtrs NEW
93 CITIGROUP INC 14.1K +10.4K (+283.9%) 137.3K +122.7K (+839.0%) 0.01% +0.010 pp 0.00% +0.000 pp USD9.43 +3.5% 6 qtrs
94 NEW YORK STATE COMMON RETIREMENT FUND 11.8K +— (+0.0%) 114.8K +67.9K (+144.6%) 0.01% +0.000 pp 0.00% +0.000 pp USD5.81 +68.0% 6 qtrs
95 EXODUSPOINT CAPITAL MANAGEMENT, LP 11.2K -155.6K (-93.3%) 109.3K -556.1K (-83.6%) 0.01% -0.149 pp 0.00% -0.006 pp USD3.73 +161.7% 3 qtrs
Ownership breakdown by holder

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
2.00
Bullish
Ratio by volume
1.61
Bullish
Buys
6
Sells
3
Shares acquired
5.41M
Shares disposed
3.37M
Cash buys
Cash sales
Net activity
+2,041,458
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-04-01 Tananbaum James B. Director / 10% Owner J-Other A Common Stock 1,123,337 0.00 1,123,337 I
2026-04-01 Foresite Labs, LLC 10% Owner J-Other A Common Stock 1,123,337 0.00 1,123,337 I
2026-04-01 Foresite Capital Management VI LLC 10% Owner J-Other A Common Stock 1,123,337 0.00 1,123,337 I
2026-01-26 Schroer John R. Officer A-Award A Stock Option (Right to Buy) 202,225 26.31 5.32M 202,225 D
2026-01-26 Pangali Sanam Officer A-Award A Stock Option (Right to Buy) 186,200 26.31 4.90M 186,200 D
2026-01-26 Hardiman Roy C. Officer A-Award A Stock Option (Right to Buy) 190,875 26.31 5.02M 190,875 D
2026-01-26 Goldstein David M Officer A-Award A Stock Option (Right to Buy) 216,675 26.31 5.70M 216,675 D
2026-01-26 Drappa Jorn Officer A-Award A Stock Option (Right to Buy) 221,450 26.31 5.83M 221,450 D
2026-01-26 Bradley Mark Christopher Officer A-Award A Stock Option (Right to Buy) 190,225 26.31 5.00M 190,225 D
2026-01-26 Babler Martin Director / Officer A-Award A Stock Option (Right to Buy) 745,875 26.31 19.62M 745,875 D
2026-01-09 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 588,235 17.00 10.00M 1,853,488 I
2026-01-08 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 117,647 17.00 2.00M 5,702,536 I
2026-01-08 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 294,117 17.00 5.00M 2,908,332 I
2026-01-08 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 117,647 17.00 2.00M 5,702,536 I
2025-12-31 Goldstein David M Officer Common Stock 0 0.00 8,994 I
2025-12-05 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 51,380 10.73 551.3K 1,265,253 I
2025-12-04 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 66,027 8.18 540.1K 1,078,876 I
2025-12-03 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 100,000 7.75 775.0K 1,012,849 I
2025-12-02 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 96,000 7.55 724.8K 912,849 I
2025-12-01 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 86,350 7.46 644.2K 816,849 I
2025-11-28 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 38,702 7.64 295.7K 730,499 I
2025-11-26 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 48,537 7.64 370.8K 691,797 I
2025-11-21 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 72,212 7.38 532.9K 2,614,215 I
2025-11-21 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 72,212 7.38 532.9K 2,614,215 I
2025-11-21 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 72,212 7.38 532.9K 2,614,215 I
2025-11-20 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 125,743 7.20 905.3K 643,260 I
2025-11-19 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 190,500 6.56 1.25M 2,542,003 I
2025-11-19 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 190,500 6.56 1.25M 2,542,003 I
2025-11-19 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 190,500 6.56 1.25M 2,542,003 I
2025-11-19 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 137,772 6.56 903.8K 517,517 I
2025-11-18 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 117,374 6.19 726.5K 2,351,503 I
2025-11-18 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 117,374 6.19 726.5K 2,351,503 I
2025-11-18 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 117,374 6.19 726.5K 2,351,503 I
2025-11-18 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 102,652 6.05 621.0K 379,745 I
2025-11-17 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 150,000 5.59 838.5K 2,234,129 I
2025-11-17 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 150,000 5.59 838.5K 2,234,129 I
2025-11-17 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 150,000 5.59 838.5K 2,234,129 I
2025-11-17 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 914 5.51 5.0K 277,093 I
2025-11-13 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 276,179 5.25 1.45M 276,179 I
2025-07-30 Yao Zhengbin Director A-Award A Stock Option (Right to Buy) 49,800 4.10 204.2K 49,800 D
2025-07-30 TETRAULT LYNN A. Director A-Award A Stock Option (Right to Buy) 49,800 4.10 204.2K 49,800 D
2025-07-30 Srivastava Sapna Director A-Award A Stock Option (Right to Buy) 49,800 4.10 204.2K 49,800 D
2025-07-30 Machado Patrick Director A-Award A Stock Option (Right to Buy) 49,800 4.10 204.2K 49,800 D
2025-07-30 AKKARAJU SRINIVAS Director A-Award A Stock Option (Right to Buy) 49,800 4.10 204.2K 49,800 D
2025-07-29 Schroer John R. Officer A-Award A Common Stock 28,000 0.00 28,000 D
2025-07-29 Richardson Derrick Officer A-Award A Common Stock 42,800 0.00 42,800 D
2025-07-29 Pangali Sanam Officer A-Award A Common Stock 10,000 0.00 11,111 D
2025-07-29 Hardiman Roy C. Officer A-Award A Stock Option (Right to Buy) 111,950 3.95 442.2K 111,950 D
2025-07-29 Goldstein David M Officer A-Award A Common Stock 27,000 0.00 29,115 D
2025-07-29 Drappa Jorn Officer A-Award A Common Stock 25,450 0.00 28,450 D
2025-07-29 Bradley Mark Christopher Officer A-Award A Common Stock 26,750 0.00 48,728 D
2025-07-29 Babler Martin Director / Officer A-Award A Stock Option (Right to Buy) 150,000 3.95 592.5K 150,000 D
2025-07-10 Pangali Sanam Officer A-Award A Stock Option (Right to Buy) 100,000 3.56 356.0K 100,000 D
2025-07-04 Pangali Sanam Officer Stock Option (Right to Buy) 152,400 10.29 1.57M 0 D
2025-05-21 TETRAULT LYNN A. Director Stock Option (Right to Buy) 21,027 9.26 194.7K 0 D
2025-05-21 Machado Patrick Director A-Award A Common Stock 7,064 0.00 0.07 7,064 I
2025-05-21 AyurMaya Capital Management Company, LP Director / 10% Owner A-Award A Common Stock, par value $0.0001 per share ("Common Stock") 4,493,741 0.00 15,139,707 I
2025-05-21 AKKARAJU SRINIVAS Director A-Award A Common Stock 1,214,582 0.00 4,801,370 I
2025-05-06 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 20,000 4.34 86.8K 4,247,670 I
2025-05-06 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 20,000 4.34 86.8K 4,247,670 I
2025-05-06 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 20,000 4.34 86.8K 4,247,670 I
2025-05-05 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 138,368 4.58 633.7K 3,564,786 I
2025-05-02 Tananbaum James B. Director / 10% Owner P-Purchase A Common Stock 25,000 4.62 115.5K 4,227,670 I
2025-05-02 Foresite Labs, LLC 10% Owner P-Purchase A Common Stock 25,000 4.62 115.5K 4,227,670 I
2025-05-02 Foresite Capital Management VI LLC 10% Owner P-Purchase A Common Stock 25,000 4.62 115.5K 4,227,670 I
2025-05-02 AKKARAJU SRINIVAS Director P-Purchase A Common Stock 159,920 4.55 727.6K 3,426,418 I
2025-04-02 Colowick Alan Director P-Purchase A Common Stock 2,300 7.49 17.2K 18,404 I
2025-04-01 Colowick Alan Director P-Purchase A Common Stock 16,104 6.97 112.3K 16,104 I
2025-04-01 Babler Martin Director / Officer P-Purchase A Common Stock 15,650 6.44 100.7K 106,454 I

Executive team

Top executives
EBIT / Employee
-19.2K
Shares Outstanding
123.14M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2024 Martin Babler President, Chief Executive Officer and Director 605.9K 9.75M 306.7K 10.66M 91.44%
2 2024 David Goldstein, Ph.D. Chief Scientific Officer 466.5K 2.59M 184.9K 3.24M 79.92%
3 2024 Roy Hardiman Chief Business and Strategy Officer 444.3K 2.60M 175.5K 3.22M 80.73%
4 2023 Martin Babler President, Chief Executive Officer and Director 516.0K 3.89M 185.8K 4.59M 84.72%
5 2023 David Goldstein, Ph.D. Chief Scientific Officer 380.0K 543.4K 119.7K 1.04M 52.09%
6 2023 Roy Hardiman Chief Business and Strategy Officer 380.0K 543.4K 119.7K 1.04M 52.09%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2025-06-16 DEFA14A
2025-06-16 DEF 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-14 8-K
2026-05-14 10-Q
2026-04-07 SC 13G
2026-04-03 SC 13D/A
2026-04-03 4
2026-04-03 4
2026-04-03 4
2026-03-30 8-K
2026-03-19 S-3ASR
2026-03-19 8-K

Executive team

NameTitleCompensationGender
Martin Babler President, Chief Executive Officer & Chairman 1M male
David Goldstein Chief Scientific Officer 821.2K
Jorn Drappa Chief Medical Officer & Head of Research and Development 817.1K
Roy C. Hardiman Chief Business & Strategy Officer 619.8K male
Kolbot By Senior Vice President & Head of Technical Operations male
Mark Bradley Chief Development Officer male
Philip Nunn Senior Vice President of Pharmacology & Project Team Leader male
Claire Langrish Senior Vice President & Head of Immunology and Translational Science female
Sanam Pangali Chief Legal Officer & Corporate Secretary female
Grace Halteh Senior Vice President & Head of Quality and Regulatory female
Jack Danilkowicz Chief Commercial Officer male
John R. Schroer Chief Financial Officer male
ESG Rating
B
BIOTECHNOLOGY
Rank: 244 out of 710
2026
E (Environmental)
60.1 / 56.3
Company / Sector avg.
S (Social)
63.6 / 62.4
Company / Sector avg.
G (Governance)
61.1 / 60.9
Company / Sector avg.
ESG Total
61.6 / 59.9
Company / Sector avg.
ESG Score History BIOTECHNOLOGY
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits