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Aclaris Therapeutics, Inc. (ACRS)

USD5.54 +0.11 (+2.03%)
US NASDAQ Healthcare Biotechnology
Address 640 Lee Road 19087
Wayne, PA, US
CEO Neal S. Walker
IPO 2015-10-06
CIK 1557746 ISIN US00461U1051

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Also trades on London Stock Exchange · 0H8T.L (USD) NASDAQ Global Select · ACRS (USD)
Description

Aclaris Therapeutics, Inc., a biopharmaceutical firm operating in the United States, is currently in the clinical development phase, focused on creating novel therapeutic agents for various immune-inflammatory conditions. The company's operations are divided into two primary divisions: the Therapeutics segment, dedicated to discovering and progressing innovative treatments to address crucial unmet needs in immuno-inflammatory disorders; and the Contract Research segment, which delivers specialized laboratory services. The company's pipeline features several investigational compounds. Among these is Zunsemetinib, an MK2 inhibitor, being developed to treat moderate to severe cases of rheumatoid arthritis, psoriatic arthritis, and hidradenitis suppurativa. Another significant candidate is ATI-1777, a soft JAK 1/3 inhibitor, intended for the management of moderate to severe atopic dermatitis. Additionally, Aclaris is advancing ATI-2138, an ITK/TXK/JAK3 inhibitor, as a potential intervention for T cell-mediated autoimmune diseases; a Gut-Biased Program targeting inflammatory bowel disease; and ATI-2231, an MK2 inhibitor, for the treatment of pancreatic and metastatic breast cancer. Established in 2012, Aclaris Therapeutics, Inc. has its corporate headquarters situated in Wayne, Pennsylvania.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
USD5.54 +0.11 (+2.03%)
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Volume Profile
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Liquidity & share structure
Average Volume
2M
Beta
0.80
Float Shares
104.53M
Free Float %
86.7%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.41% +6.00% +22.52% +47.32% +105.39% +64.45% +296.00% -37.26% -77.26% -70.76% -55.00%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Analyst Consensus (16 ratings, all time) Buy
Price Targets & DCF
Current price
5.54
Low 10.00 +80.5%
Consensus 10.60 +91.3%
Median 10.00 +80.5%
High 12.00 +116.6%
Ratings Trend (MoM) 90% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 8 +1
Hold 1 0
Sell 0 0
Strong Sell 0 0
Price Target Summary
Period # Analysts Avg Target
Last Month 4
10.75
+94.0%
Last Quarter 4
10.75
+94.0%
Last Year 5
10.60
+91.3%
All Time 9
10.67
+92.6%
Quality scores
Altman Z-Score
-1.13
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -58.2% Q1'26: +37.2% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +69.0% Q1'26: -25.0% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -791.1% Q1'26: -909.3% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -829.6% Q1'26: -1,111.8% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -449.4% Q1'26: -220.7% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +58.7% Q1'26: +5.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.03× Q1'26: -0.02× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.78) × ERP
WACC = 100% × Ke + 0% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 5.54
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
8 Rev. Ana.
8 EPS Ana.
Dec 2027
8 Rev. Ana.
8 EPS Ana.
Dec 2028
7 Rev. Ana.
7 EPS Ana.
Dec 2029
3 Rev. Ana.
2 EPS Ana.
Dec 2030
6 Rev. Ana.
5 EPS Ana.
Revenue
1.68M
est: 1.21M (+38.6%)
10.09M
est: 10.14M (-0.5%)
4.23M
est: 22.59M (-81.3%)
6.48M
est: 6.29M (+3.0%)
6.76M
est: 7.05M (-4.1%)
29.75M
est: 23.99M (+24.0%)
31.25M
est: 32.02M (-2.4%)
18.72M
est: 11.61M (+61.3%)
7.83M
est: 8.76M (-10.7%)
5.81M
912.3K – 10.14M
-33.7% YoY
5.93M
904.8K – 12.06M
+2.1% YoY
6.90M
1.07M – 13.05M
+16.3% YoY
28.37M
4.39M – 53.66M
+311.3% YoY
114.38M
17.70M – 216.37M
+303.2% YoY
EBITDA
-53.45M
est: -1.21M (-4,303.0%)
-80.78M
est: -10.14M (-696.8%)
-90.23M
est: -112.87M (+20.1%)
-47.20M
est: -50.11M (+5.8%)
-64.46M
est: -76.78M (+16.0%)
-84.36M
est: -86.31M (+2.3%)
-115.45M
est: -32.02M (-260.6%)
-51.72M
est: -11.61M (-345.5%)
-64.47M
est: -8.76M (-635.8%)
-5.81M
-10.14M – -912.3K
+33.7% YoY
-5.93M
-12.06M – -904.8K
-2.1% YoY
-6.90M
-13.05M – -1.07M
-16.3% YoY
-28.37M
-53.66M – -4.39M
-311.3% YoY
-114.38M
-216.37M – -17.70M
-303.2% YoY
EBIT
-53.36M
est: -1.21M (-4,295.5%)
-84.78M
est: -10.14M (-736.2%)
-91.82M
est: -88.79M (-3.4%)
-48.52M
est: -51.26M (+5.3%)
-65.38M
est: -76.72M (+14.8%)
-85.15M
est: -87.26M (+2.4%)
-116.31M
est: -32.02M (-263.3%)
-52.53M
est: -11.61M (-352.5%)
-64.92M
est: -8.76M (-641.0%)
-5.81M
-10.14M – -912.3K
+33.7% YoY
-5.93M
-12.06M – -904.8K
-2.1% YoY
-6.90M
-13.05M – -1.07M
-16.3% YoY
-28.37M
-53.66M – -4.39M
-311.3% YoY
-114.38M
-216.37M – -17.70M
-303.2% YoY
Net Income
-68.52M
est: -187.28M (+63.4%)
-132.74M
est: -406.84M (+67.4%)
-161.35M
est: -117.45M (-37.4%)
-51.02M
est: -51.47M (+0.9%)
-90.87M
est: -77.55M (-17.2%)
-86.91M
est: -105.32M (+17.5%)
-88.48M
est: -58.68M (-50.8%)
-132.07M
est: -134.65M (+1.9%)
-64.92M
est: -65.12M (+0.3%)
-85.05M
-89.42M – -62.20M
-30.6% YoY
-102.02M
-103.92M – -55.02M
-19.9% YoY
-119.43M
-122.38M – -38.83M
-17.1% YoY
-102.69M
-221.72M – 10.15M
+14.0% YoY
-85.87M
-185.40M – 8.48M
+16.4% YoY
SGA
33.11M
est: 2.35M (+1,307.7%)
75.65M
est: 19.64M (+285.1%)
27.83M
est: 43.76M (-36.4%)
20.53M
est: 12.19M (+68.3%)
23.62M
est: 13.66M (+72.9%)
25.13M
est: 46.48M (-45.9%)
31.10M
est: 59.72M (-47.9%)
22.20M
est: 21.66M (+2.5%)
21.97M
est: 16.34M (+34.4%)
10.83M
1.70M – 18.91M
-33.7% YoY
11.06M
1.69M – 22.50M
+2.1% YoY
12.87M
1.99M – 24.34M
+16.3% YoY
52.92M
8.19M – 100.11M
+311.3% YoY
213.36M
33.02M – 403.61M
+303.2% YoY
EPS
-2.44
est: -2.42 (-0.7%)
-4.03
est: -5.26 (+23.4%)
-3.46
est: -3.46 (+0.0%)
-1.20
est: -1.84 (+34.8%)
-1.60
est: -1.61 (+0.4%)
-1.33
est: -1.44 (+7.5%)
-1.27
est: -0.83 (-53.7%)
-1.71
est: -0.82 (-108.5%)
-0.53
est: -0.53 (-0.8%)
-0.66
-0.73 – -0.51
-24.6% YoY
-0.67
-0.85 – -0.45
-2.0% YoY
-0.77
-1.00 – -0.32
-15.9% YoY
-0.84
-1.81 – 0.08
-8.1% YoY
-0.70
-1.51 – 0.07
+16.4% YoY
Recent Grade Changes (3M)
Date Firm Previous New Grade Action
2026-05-05 Piper Sandler Overweight Overweight Maintain
2026-04-29 Wedbush Outperform Outperform Maintain
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 2/5
2026-05-06 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-05-01 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C- 1/5 1/5 1/5 1/5 3/5 1/5 2/5
2026-04-24 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C- 1/5 1/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-53.04M
OE per share TTM
-0.43
Owner's Yield
-8.47%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
8.7%

Ownership Overview

Ownership breakdown
At a glance
Institutional holders
19
Total invested
1.87M
Insider transactions (90d)
2
Beneficial owners (>5%)
17
Beneficial owners (>5%)
# Reporting person Amount owned % of class Sole voting Shared voting Sole dispositive Shared dispositive Type Citizenship Filing date SEC filing
1 Biosion, Inc. 11.28M 9.50% 11.28M 11.28M CO The People’s Republic of China 2024-11-25
2 Vivo Opportunity Fund Holdings, L.P. 7.96M 7.40% 7.96M 7.96M PN Delaware 2024-11-21
3 Vivo Opportunity, LLC 7.96M 7.40% 7.96M 7.96M OO Delaware 2024-11-21
4 Rock Springs Capital Management LP 6.76M 6.32% 6.76M 6.76M IA Delaware 2024-11-22
5 The Vanguard Group - 23-1945930 4.72M 6.67% 123.0K 4.55M 170.7K IA Pennsylvania 2024-02-13
6 BML Investment Partners, L.P. 4.50M 6.40% 4.50M 4.50M PN Delaware 2024-01-16
7 BVF Inc. 3.36M 5.00% 3.36M CO Delaware 2023-03-16
8 Mark N. Lampert 3.36M 5.00% 3.36M IN Delaware 2023-03-16
9 BVF GP Holdings LLC 3.16M 4.70% 3.16M OO Delaware 2023-03-16
10 Israel A. Englander 3.01M 4.20% 3.01M 3.01M IN Delaware 2024-10-09
11 Millennium Group Management LLC 3.01M 4.20% 3.01M 3.01M OO Delaware 2024-10-09
12 Millennium Management LLC 3.01M 4.20% 3.01M 3.01M OO Delaware 2024-10-09
13 Vivo Asia Opportunity Fund Holdings, L.P. 933.7K 0.90% 933.7K 933.7K PN Delaware 2024-11-21
14 Vivo Opportunity Cayman, LLC 933.7K 0.90% 933.7K 933.7K OO Delaware 2024-11-21
15 BVF Partners OS Ltd. 156.1K 1.00% 156.1K CO Delaware 2023-03-16
16 Biotechnology Value Trading Fund OS LP 156.1K 1.00% 156.1K PN Delaware 2023-03-16
17 2. 10.00 5.10% 3.59M HC, IN Delaware 2023-09-05

Institutional Activity (13F)

Institutional ownership trend From To
13F snapshot — 2026 Q1
Investors holding
19
-104 vs prev Q
New positions
4
Closed positions
106
Increased
9
Reduced
5
Put/Call ratio
0.00
Calls held
Puts held
Top institutional holders
# Investor Shares / Δ Mkt value / Δ Own% / Δ Weight% / Δ Avg px / Perf. Hold / Status
1 BML CAPITAL MANAGEMENT, LLC 14.25M +— (+0.0%) 42.89M +15.8M (+58.4%) 11.62% -0.004 pp 37.08% +12.285 pp USD1.21 +148.8% 9 qtrs
2 VIVO CAPITAL, LLC 8.89M +— (+0.0%) 26.76M +9.9M (+58.4%) 7.25% -0.002 pp 1.73% +0.370 pp USD2.48 +21.4% 5 qtrs
3 BLACKROCK, INC. 6.80M +1.1M (+19.6%) 20.48M +9.7M (+89.4%) 5.55% +0.907 pp 0.00% +0.000 pp USD1.64 +83.5% 6 qtrs
4 VANGUARD GROUP INC 6.50M -13.4K (-0.2%) 19.57M +7.2M (+58.1%) 5.30% -0.013 pp 0.00% +0.000 pp USD7.68 -60.8% 41 qtrs
5 ROCK SPRINGS CAPITAL MANAGEMENT LP 4.45M -155.6K (-3.4%) 13.41M +4.6M (+53.1%) 3.63% -0.128 pp 0.69% +0.176 pp USD6.82 -55.9% 41 qtrs
6 DECHENG CAPITAL LLC 4.04M +— (+0.0%) 12.17M +4.5M (+58.4%) 3.30% -0.001 pp 1.64% +0.297 pp USD2.06 +46.1% 5 qtrs
7 MORGAN STANLEY 3.42M -661.9K (-16.2%) 10.28M +2.5M (+32.7%) 2.79% -0.541 pp 0.00% +0.000 pp USD2.04 +47.5% 41 qtrs
8 ADAGE CAPITAL PARTNERS GP, L.L.C. 3.37M -1.9M (-36.1%) 10.15M +118.2K (+1.2%) 2.75% -1.557 pp 0.02% -0.001 pp USD2.48 +21.4% 5 qtrs
9 GEODE CAPITAL MANAGEMENT, LLC 2.39M +3.2K (+0.1%) 7.20M +2.7M (+58.6%) 1.95% +0.002 pp 0.00% +0.000 pp USD4.75 -36.6% 41 qtrs
10 ACADIAN ASSET MANAGEMENT LLC 2.12M -204.6K (-8.8%) 6.39M +2.0M (+44.6%) 1.73% -0.168 pp 0.01% +0.003 pp USD1.18 +155.1% 9 qtrs
11 D. E. SHAW & CO., INC. 2.10M -276.6K (-11.7%) 6.31M +1.8M (+40.0%) 1.71% -0.226 pp 0.00% +0.001 pp USD1.28 +135.2% 11 qtrs
12 KOTLER KEVIN 1.71M +1.7M (+100.0%) 5.13M +5.1M (+100.0%) 1.39% +1.391 pp 1.20% +1.201 pp USD3.01 +0.0% 1 qtrs NEW
13 PALO ALTO INVESTORS LP 1.57M +— (+0.0%) 4.72M +1.7M (+58.4%) 1.28% 0.000 pp 0.66% +0.106 pp USD1.43 +110.5% 8 qtrs
14 STATE STREET CORP 1.51M +393.3K (+35.3%) 4.53M +2.4M (+114.4%) 1.23% +0.320 pp 0.00% +0.000 pp USD3.80 -20.8% 41 qtrs
15 CONNOR, CLARK & LUNN INVESTMENT MANAGEMENT LTD. 1.43M +366.5K (+34.3%) 4.32M +2.3M (+112.8%) 1.17% +0.299 pp 0.01% +0.005 pp USD2.24 +34.4% 14 qtrs
16 CITADEL ADVISORS LLC 1.21M -227.4K (-15.9%) 3.63M +905.8K (+33.3%) 0.98% -0.186 pp 0.00% +0.000 pp USD1.85 +62.7% 38 qtrs
17 RENAISSANCE TECHNOLOGIES LLC 1.13M -494.4K (-30.5%) 3.39M +309.8K (+10.1%) 0.92% -0.404 pp 0.01% +0.001 pp USD1.52 +98.0% 29 qtrs
18 MILLENNIUM MANAGEMENT LLC 1.05M -501.2K (-32.2%) 3.17M +216.8K (+7.3%) 0.86% -0.409 pp 0.00% +0.000 pp USD3.25 -7.4% 28 qtrs
19 DEUTSCHE BANK AG\ 987.4K +64.0K (+6.9%) 2.97M +1.2M (+69.4%) 0.81% +0.052 pp 0.00% +0.000 pp USD3.49 -13.8% 41 qtrs
20 ALDEBARAN CAPITAL, LLC 954.3K -33.4K (-3.4%) 2.87M +995.7K (+53.1%) 0.78% -0.028 pp 2.58% +0.852 pp USD1.15 +161.7% 7 qtrs
21 SUSQUEHANNA INTERNATIONAL GROUP, LLP 916.8K +880.6K (+2,430.1%) 2.76M +2.7M (+3,908.3%) 0.75% +0.718 pp 0.00% +0.000 pp USD2.96 +1.7% 21 qtrs
22 BOLLARD GROUP LLC 804.4K -421.0K (-34.4%) 2.42M +93.0K (+4.0%) 0.66% -0.344 pp 0.06% +0.006 pp USD1.53 +96.7% 4 qtrs
23 WOODLINE PARTNERS LP 742.0K +742.0K (+100.0%) 2.23M +2.2M (+100.0%) 0.61% +0.605 pp 0.01% +0.009 pp USD3.01 +0.0% 1 qtrs NEW
24 THREE BRIDGE WEALTH ADVISORS, LLC 714.8K +— (+0.0%) 2.15M +793.5K (+58.4%) 0.58% 0.000 pp 0.57% +0.217 pp USD1.90 +58.4% 2 qtrs
25 NORTHERN TRUST CORP 664.3K -36.6K (-5.2%) 2.00M +667.9K (+50.2%) 0.54% -0.030 pp 0.00% +0.000 pp USD4.03 -25.3% 41 qtrs
26 GOLDMAN SACHS GROUP INC 632.5K -323.5K (-33.8%) 1.90M +87.3K (+4.8%) 0.52% -0.264 pp 0.00% +0.000 pp USD1.95 +54.4% 36 qtrs
27 JPMORGAN CHASE & CO 626.0K -132.6K (-17.5%) 1.88M +442.9K (+30.7%) 0.51% -0.108 pp 0.00% +0.000 pp USD1.82 +65.4% 20 qtrs
28 ADAR1 CAPITAL MANAGEMENT, LLC 614.0K +240.3K (+64.3%) 1.85M +1.1M (+160.3%) 0.50% +0.196 pp 0.14% +0.069 pp USD2.33 +29.2% 2 qtrs
29 LOGOS GLOBAL MANAGEMENT LP 600.0K -900.0K (-60.0%) 1.81M -1.0M (-36.6%) 0.49% -0.734 pp 0.11% -0.146 pp USD2.48 +21.4% 5 qtrs
30 TWO SIGMA INVESTMENTS, LP 574.2K +206.1K (+56.0%) 1.73M +1.0M (+147.1%) 0.47% +0.168 pp 0.00% +0.001 pp USD1.82 +65.4% 13 qtrs
31 MARSHALL WACE, LLP 485.5K -1.2M (-71.7%) 1.46M -1.8M (-55.2%) 0.40% -1.006 pp 0.00% -0.002 pp USD2.48 +21.4% 5 qtrs
32 QUBE RESEARCH & TECHNOLOGIES LTD 447.2K -97.6K (-17.9%) 1.35M +311.0K (+30.0%) 0.36% -0.080 pp 0.00% +0.000 pp USD1.67 +80.2% 9 qtrs
33 AISLING CAPITAL MANAGEMENT LP 434.5K +— (+0.0%) 1.31M +482.2K (+58.4%) 0.35% 0.000 pp 0.27% +0.092 pp USD7.39 -59.3% 29 qtrs
34 UBS GROUP AG 362.5K +257.4K (+244.8%) 1.09M +891.5K (+446.3%) 0.30% +0.210 pp 0.00% +0.000 pp USD2.72 +10.7% 29 qtrs
35 BRIDGEWAY CAPITAL MANAGEMENT, LLC 330.0K -63.3K (-16.1%) 993.4K +246.1K (+32.9%) 0.27% -0.052 pp 0.02% +0.005 pp USD1.50 +100.7% 7 qtrs
36 AMERIPRISE FINANCIAL INC 318.4K -959.4K (-75.1%) 958.5K -1.5M (-60.5%) 0.26% -0.783 pp 0.00% 0.000 pp USD1.90 +58.4% 2 qtrs
37 HIGHTOWER ADVISORS, LLC 305.9K -3.4K (-1.1%) 920.9K +333.2K (+56.7%) 0.25% -0.003 pp 0.00% +0.000 pp USD11.64 -74.1% 39 qtrs
38 CHARLES SCHWAB INVESTMENT MANAGEMENT INC 284.6K +42.6K (+17.6%) 856.7K +396.9K (+86.3%) 0.23% +0.035 pp 0.00% +0.000 pp USD1.77 +70.1% 41 qtrs
39 DIMENSIONAL FUND ADVISORS LP 270.9K +106.6K (+64.9%) 814.6K +502.5K (+161.0%) 0.22% +0.087 pp 0.00% +0.000 pp USD3.27 -8.0% 14 qtrs
40 RAYMOND JAMES FINANCIAL INC 269.7K -13.8K (-4.9%) 811.7K +273.1K (+50.7%) 0.22% -0.011 pp 0.00% +0.000 pp USD2.05 +46.8% 5 qtrs
41 WELLINGTON MANAGEMENT GROUP LLP 264.4K +264.4K (+100.0%) 795.7K +795.7K (+100.0%) 0.22% +0.216 pp 0.00% +0.000 pp USD3.01 +0.0% 1 qtrs NEW
42 TWO SIGMA ADVISERS, LP 255.4K -94.7K (-27.0%) 768.8K +103.6K (+15.6%) 0.21% -0.077 pp 0.00% +0.000 pp USD1.66 +81.3% 12 qtrs
43 NUVEEN, LLC 237.8K +— (+0.0%) 715.9K +264.0K (+58.4%) 0.19% 0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
44 INVESCO LTD. 209.9K +47.4K (+29.2%) 631.8K +323.1K (+104.7%) 0.17% +0.039 pp 0.00% +0.000 pp USD1.92 +56.8% 5 qtrs
45 BANK OF NEW YORK MELLON CORP 203.5K -16.6K (-7.5%) 612.6K +194.4K (+46.5%) 0.17% -0.014 pp 0.00% +0.000 pp USD1.44 +109.0% 4 qtrs
46 ASSENAGON ASSET MANAGEMENT S.A. 154.6K +— (+0.0%) 465.2K +171.6K (+58.4%) 0.13% +0.000 pp 0.00% +0.000 pp USD1.72 +75.0% 6 qtrs
47 BARCLAYS PLC 143.4K +123.0K (+603.3%) 431.7K +408.2K (+1,740.7%) 0.12% +0.100 pp 0.00% +0.000 pp USD2.89 +4.2% 19 qtrs
48 PRICE T ROWE ASSOCIATES INC /MD/ 140.2K +— (+0.0%) 422.0K +155.0K (+58.1%) 0.11% +0.000 pp 0.00% +0.000 pp USD7.31 -58.8% 20 qtrs
49 XTX TOPCO LTD 112.9K +49.0K (+76.6%) 339.9K +218.4K (+179.8%) 0.09% +0.040 pp 0.01% +0.003 pp USD2.28 +32.0% 9 qtrs
50 107.4K +107.4K (+100.0%) 323.3K +323.3K (+100.0%) 0.09% +0.088 pp 0.25% +0.246 pp USD3.01 +0.0% 1 qtrs NEW
51 WELLS FARGO & COMPANY/MN 104.5K +36.4K (+53.5%) 314.4K +185.2K (+143.2%) 0.09% +0.030 pp 0.00% +0.000 pp USD2.30 +30.9% 41 qtrs
52 AQR CAPITAL MANAGEMENT LLC 103.8K +68.8K (+197.0%) 312.4K +246.0K (+370.4%) 0.08% +0.056 pp 0.00% +0.000 pp USD2.64 +14.0% 2 qtrs
53 ALPS ADVISORS INC 89.0K +89.0K (+100.0%) 267.8K +267.8K (+100.0%) 0.07% +0.073 pp 0.00% +0.002 pp USD3.01 +0.0% 1 qtrs NEW
54 POINT72 ASSET MANAGEMENT, L.P. 87.2K +87.2K (+100.0%) 262.4K +262.4K (+100.0%) 0.07% +0.071 pp 0.00% +0.000 pp USD3.01 +0.0% 1 qtrs NEW
55 AMERICAN CENTURY COMPANIES INC 77.6K +45.8K (+144.0%) 233.5K +173.1K (+286.6%) 0.06% +0.037 pp 0.00% +0.000 pp USD2.56 +17.6% 2 qtrs
56 RHUMBLINE ADVISERS 71.8K -19.4K (-21.3%) 216.1K +42.8K (+24.7%) 0.06% -0.016 pp 0.00% +0.000 pp USD1.45 +107.6% 3 qtrs
57 PANAGORA ASSET MANAGEMENT INC 68.2K +22.6K (+49.6%) 205.3K +118.6K (+137.0%) 0.06% +0.018 pp 0.00% +0.000 pp USD2.27 +32.6% 2 qtrs
58 BANK OF AMERICA CORP /DE/ 64.5K -10.7K (-14.2%) 194.2K +51.3K (+35.9%) 0.05% -0.009 pp 0.00% +0.000 pp USD2.56 +17.6% 19 qtrs
59 QUADRATURE CAPITAL LTD 57.7K +26.1K (+82.8%) 173.6K +114.0K (+191.1%) 0.05% +0.021 pp 0.00% +0.001 pp USD2.20 +36.8% 4 qtrs
60 CREATIVE PLANNING 51.2K +51.2K (+100.0%) 154.0K +154.0K (+100.0%) 0.04% +0.042 pp 0.00% +0.000 pp USD3.01 +0.0% 1 qtrs NEW
61 INTECH INVESTMENT MANAGEMENT LLC 46.6K +7.7K (+19.8%) 140.4K +66.4K (+89.8%) 0.04% +0.006 pp 0.00% +0.001 pp USD1.68 +79.2% 3 qtrs
62 FMR LLC 45.8K +5.5K (+13.5%) 137.9K +61.2K (+79.8%) 0.04% +0.004 pp 0.00% +0.000 pp USD20.30 -85.2% 41 qtrs
63 MIRAE ASSET GLOBAL ETFS HOLDINGS LTD. 42.6K -187.0 (-0.4%) 128.1K +46.9K (+57.7%) 0.03% 0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
64 MAN GROUP PLC 42.4K +42.4K (+100.0%) 127.7K +127.7K (+100.0%) 0.03% +0.035 pp 0.00% +0.000 pp USD3.01 +0.0% 1 qtrs NEW
65 CAMBRIDGE INVESTMENT RESEARCH ADVISORS, INC. 41.9K +— (+0.0%) 126.0K +46.0K (+57.5%) 0.03% +0.000 pp 0.00% +0.000 pp USD1.39 +116.5% 26 qtrs
66 CITIGROUP INC 41.6K +39.7K (+2,051.4%) 125.3K +121.6K (+3,308.8%) 0.03% +0.032 pp 0.00% +0.000 pp USD2.95 +2.0% 21 qtrs
67 SUSQUEHANNA PORTFOLIO STRATEGIES, LLC 39.7K +39.7K (+100.0%) 119.5K +119.5K (+100.0%) 0.03% +0.032 pp 0.00% +0.002 pp USD3.01 +0.0% 1 qtrs NEW
68 MANUFACTURERS LIFE INSURANCE COMPANY, THE 29.0K -4.5K (-13.4%) 87.3K +23.6K (+37.1%) 0.02% -0.004 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
69 VALEO FINANCIAL ADVISORS, LLC 27.5K +27.5K (+100.0%) 82.9K +82.9K (+100.0%) 0.02% +0.023 pp 0.00% +0.002 pp USD3.01 +0.0% 1 qtrs NEW
70 NEW YORK STATE COMMON RETIREMENT FUND 27.3K -21.1K (-43.6%) 82.2K -9.8K (-10.6%) 0.02% -0.017 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
71 JANE STREET GROUP, LLC 27.2K -45.9K (-62.8%) 81.9K -57.0K (-41.0%) 0.02% -0.037 pp 0.00% +0.000 pp USD1.90 +58.4% 12 qtrs
72 VONTOBEL HOLDING LTD. 26.0K +— (+0.0%) 78.3K +28.9K (+58.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD3.11 -3.2% 12 qtrs
73 METLIFE INVESTMENT MANAGEMENT, LLC 25.6K -9.7K (-27.5%) 77.0K +9.9K (+14.8%) 0.02% -0.008 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
74 AXQ CAPITAL, LP 24.2K +10.2K (+73.1%) 72.8K +46.3K (+174.3%) 0.02% +0.008 pp 0.02% +0.006 pp USD2.37 +27.0% 2 qtrs
75 PERSISTENT ASSET PARTNERS LTD 22.3K +22.3K (+100.0%) 67.0K +67.0K (+100.0%) 0.02% +0.018 pp 0.03% +0.030 pp USD3.01 +0.0% 1 qtrs NEW
76 PROSHARE ADVISORS LLC 21.6K +6.7K (+45.4%) 64.9K +36.7K (+130.4%) 0.02% +0.006 pp 0.00% +0.000 pp USD1.92 +56.8% 3 qtrs
77 BNP PARIBAS ARBITRAGE, SNC 21.5K -5.2K (-19.3%) 64.8K +14.1K (+27.8%) 0.02% -0.004 pp 0.00% +0.000 pp USD1.72 +75.0% 19 qtrs
78 POLICE & FIREMEN'S RETIREMENT SYSTEM OF NEW JERSEY 19.7K +— (+0.0%) 59.3K +21.9K (+58.4%) 0.02% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
79 NEUBERGER BERMAN GROUP LLC 19.0K +6.3K (+49.2%) 57.1K +32.9K (+136.4%) 0.02% +0.005 pp 0.00% +0.000 pp USD1.70 +77.1% 9 qtrs
80 CRA FINANCIAL SERVICES, LLC 17.8K +— (+0.0%) 53.5K +19.7K (+58.4%) 0.01% +0.000 pp 0.01% +0.002 pp USD1.42 +112.0% 3 qtrs
81 CHINA UNIVERSAL ASSET MANAGEMENT CO., LTD. 17.7K +17.7K (+100.0%) 53.1K +53.1K (+100.0%) 0.01% +0.014 pp 0.00% +0.004 pp USD3.01 +0.0% 1 qtrs NEW
82 CIBC ASSET MANAGEMENT INC 17.4K +17.4K (+100.0%) 52.5K +52.5K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD3.01 +0.0% 1 qtrs NEW
83 VOYA INVESTMENT MANAGEMENT LLC 17.2K +— (+0.0%) 51.9K +19.1K (+58.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
84 SIMPLEX TRADING, LLC 16.7K +16.7K (+100.0%) 50.2K +50.2K (+100.0%) 0.01% +0.014 pp 0.00% +0.000 pp USD3.01 +0.0% 22 qtrs
85 MARINER, LLC 16.7K +558.0 (+3.5%) 50.2K +19.5K (+63.8%) 0.01% +0.001 pp 0.00% +0.000 pp USD1.15 +161.7% 9 qtrs
86 SG AMERICAS SECURITIES, LLC 15.4K -6.6K (-29.9%) 46.0K +4.0K (+9.5%) 0.01% -0.005 pp 0.00% 0.000 pp USD1.53 +96.7% 4 qtrs
87 ALLIANCEBERNSTEIN L.P. 15.2K +— (+0.0%) 45.8K +16.9K (+58.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
88 GROUP ONE TRADING, L.P. 12.4K +10.7K (+611.3%) 37.4K +34.1K (+1,026.9%) 0.01% +0.009 pp 0.00% +0.000 pp USD2.79 +7.9% 3 qtrs
89 R SQUARED LTD 12.4K +12.4K (+100.0%) 37.3K +37.3K (+100.0%) 0.01% +0.010 pp 0.02% +0.018 pp USD3.01 +0.0% 1 qtrs NEW
90 TWO SIGMA SECURITIES, LLC 11.5K +959.0 (+9.1%) 34.8K +14.6K (+72.8%) 0.01% +0.001 pp 0.00% +0.002 pp USD1.99 +51.3% 2 qtrs
91 JEFFERIES FINANCIAL GROUP INC. 11.0K +2.0 (+0.0%) 33.1K +12.2K (+58.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD3.97 -24.2% 12 qtrs
92 VICTORY CAPITAL MANAGEMENT INC 10.7K +23.0 (+0.2%) 32.1K +11.9K (+58.8%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.53 +96.7% 4 qtrs
93 MERCER GLOBAL ADVISORS INC /ADV 10.2K -293.0 (-2.8%) 30.6K +10.7K (+54.0%) 0.01% 0.000 pp 0.00% +0.000 pp USD1.54 +95.5% 4 qtrs
94 RUSSELL INVESTMENTS GROUP, LTD. 9.8K +173.0 (+1.8%) 29.5K +11.2K (+61.3%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.87 +61.0% 10 qtrs
95 AMERITAS INVESTMENT PARTNERS, INC. 9.3K +— (+0.0%) 27.9K +10.3K (+58.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
96 LEGAL & GENERAL GROUP PLC 8.2K +— (+0.0%) 24.8K +9.1K (+58.4%) 0.01% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
97 CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM 5.6K -19.0 (-0.3%) 17.0K +6.2K (+57.9%) 0.00% +0.000 pp 0.00% +0.000 pp USD1.42 +112.0% 3 qtrs
98 STERLING CAPITAL MANAGEMENT LLC 5.3K -692.0 (-11.6%) 15.9K +4.6K (+40.1%) 0.00% -0.001 pp 0.00% +0.000 pp USD1.70 +77.1% 3 qtrs
Ownership breakdown by holder

ETF Ownership

Top ETFs holding this stock Held by 75 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Pharmaceuticals ETF XPH 0.92% 4.32M 0.35%
2 Invesco NASDAQ Future Gen 200 ETF QQQS 0.61% 134.5K 0.20%
3 ALPS Medical Breakthroughs ETF SBIO 0.40% 851.0K 0.50%
4 Direxion Daily Pharmaceutical & Medical Bull 3X ETF PILL 0.19% 44.4K 1.22%
5 iShares Micro-Cap ETF IWC 0.15% 2.21M 0.60%
6 Vanguard U.S. Momentum Factor ETF VFMO 0.07% 1.25M 0.13%
7 iShares Nasdaq US Biotechnology UCITS ETF BTEE.L 0.05% 39.9K 0.35%
8 iShares Nasdaq US Biotechnology UCITS ETF BTEC.L 0.05% 596.1K 0.35%
9 Invesco NASDAQ Biotech UCITS ETF SBIO.L 0.05% 247.9K 0.40%
10 Invesco Nasdaq Biotechnology ETF IBBQ 0.05% 40.0K 0.19%

Insider Activity

Insider Activity — Latest Quarter
Ratio by transactions
1.09
Neutral
Ratio by volume
3.00
Bullish
Buys
25
Sells
23
Shares acquired
3.67M
Shares disposed
313.9K
Cash buys
Cash sales
Net activity
+3,356,222
Insider buys vs sells (history) From To
Recent insider transactions From To
Date Person Role Transaction A/D Security Shares Price Value Owned after D/I Filing
2026-05-01 Hall Jesse Wayne Officer M-Exempt D Restricted Stock Units 36,375 0.00 109,125 D
2026-04-23 Leonard Braden Michael 10% Owner S-Sale D Common Stock 300,000 4.53 1.36M 13,950,000 I
2026-03-01 Balthaser Kevin Officer M-Exempt A Common Stock 2,375 0.00 188,130 D
2026-02-03 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 63,475 0.00 190,425 D
2026-02-03 Loerop James Officer F-InKind D Common Stock 5,937 3.47 20.6K 192,260 D
2026-02-03 Davis Hugh M. Director / Officer M-Exempt D Restricted Stock Units 18,675 0.00 56,025 D
2026-02-03 Balthaser Kevin Officer F-InKind D Common Stock 6,449 3.47 22.4K 185,755 D
2026-02-02 Walker Neal Director / Officer A-Award A Restricted Stock Units 274,800 0.00 274,800 D
2026-02-02 Loerop James Officer A-Award A Restricted Stock Units 97,700 0.00 97,700 D
2026-02-02 Kolbeck Roland Wilhelm Officer A-Award A Restricted Stock Units 95,700 0.00 95,700 D
2026-02-02 Hall Jesse Wayne Officer A-Award A Restricted Stock Units 98,100 0.00 98,100 D
2026-02-02 Davis Hugh M. Director / Officer A-Award A Restricted Stock Units 96,100 0.00 96,100 D
2026-02-02 Balthaser Kevin Officer A-Award A Restricted Stock Units 99,100 0.00 99,100 D
2026-02-01 Loerop James Officer M-Exempt D Resticted Stock Units 7,500 0.00 7,500 D
2026-02-01 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 14,750 0.00 29,500 D
2026-01-02 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 29,150 0.00 30,034 D
2026-01-02 Loerop James Officer M-Exempt A Common Stock 18,150 0.00 161,212 D
2026-01-02 Balthaser Kevin Officer M-Exempt A Common Stock 13,200 0.00 164,874 D
2026-01-01 Balthaser Kevin Officer M-Exempt A Common Stock 7,500 0.00 153,924 D
2025-12-31 Loerop James Officer M-Exempt D Restricted Stock Units 73,750 0.00 0 D
2025-12-31 Balthaser Kevin Officer F-InKind D Common Stock 19,934 3.01 60.0K 146,424 D
2025-12-02 Davis Hugh M. Director / Officer M-Exempt D Restricted Stock Units 26,750 0.00 80,250 D
2025-08-01 Kolbeck Roland Wilhelm Officer A-Award A Employee Stock Option (right to buy) 510,000 1.53 780.3K 510,000 D
2025-07-28 Kolbeck Roland Wilhelm 0 0.00 0
2025-06-06 SCHIFF ANDREW N Director M-Exempt D Restricted Stock Units 4,793 0.00 0 D
2025-06-06 Molineaux Christopher P. Director M-Exempt A Common Stock 4,793 0.00 57,956 D
2025-06-06 Mehra Anand Director M-Exempt D Restricted Stock Units 4,793 0.00 0 D
2025-06-06 MILANO VINCENT Director M-Exempt D Restricted Stock Units 4,793 0.00 0 D
2025-06-06 Humphries William D. Director M-Exempt A Common Stock 4,793 0.00 33,525 D
2025-06-06 GOWEN MAXINE Director M-Exempt A Common Stock 4,793 0.00 21,754 D
2025-06-05 SCHIFF ANDREW N Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-06-05 Molineaux Christopher P. Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-06-05 Mehra Anand Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-06-05 MILANO VINCENT Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-06-05 Humphries William D. Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-06-05 GOWEN MAXINE Director A-Award A Restricted Stock Units 11,580 0.00 11,580 D
2025-05-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,467 0.00 0 D
2025-05-01 Hall Jesse Wayne 0 0.00 0
2025-04-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,467 0.00 1,476,374 D
2025-03-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,466 0.00 18,934 D
2025-03-01 Monahan Joseph Officer M-Exempt D Restricted Stock Units 50,000 0.00 0 D
2025-03-01 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 1,100 0.00 0 D
2025-02-03 Walker Neal Director / Officer A-Award A Restricted Stock Units 253,900 0.00 253,900 D
2025-02-03 Monahan Joseph Officer A-Award A Restricted Stock Units 83,900 0.00 83,900 D
2025-02-03 Loerop James Officer A-Award A Restricted Stock Units 83,500 0.00 83,500 D
2025-02-03 Davis Hugh M. Director / Officer A-Award A Employee Stock Option (Right to Buy) 261,600 2.40 627.8K 261,600 D
2025-02-03 Balthaser Kevin Officer A-Award A Restricted Stock Units 88,100 0.00 88,100 D
2025-02-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,467 0.00 28,400 D
2025-02-01 Monahan Joseph Officer M-Exempt A Common Stock 7,500 0.00 228,562 D
2025-02-01 Loerop James Officer M-Exempt D Resticted Stock Units 7,500 0.00 15,000 D
2025-02-01 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 14,750 0.00 44,250 D
2025-01-02 Walker Neal Director / Officer M-Exempt A Common Stock 29,149 0.00 1,468,342 D
2025-01-02 Monahan Joseph Officer A-Award A Restricted Stock Units 52,667 0.00 52,667 D
2025-01-02 Loerop James Officer F-InKind D Common Stock 8,575 2.48 21.3K 85,253 D
2025-01-02 Balthaser Kevin Officer M-Exempt A Common Stock 13,200 0.00 85,985 D
2025-01-01 Walker Neal Director / Officer F-InKind D Common Stock 3,904 2.48 9.7K 1,439,193 D
2025-01-01 Balthaser Kevin Officer M-Exempt A Common Stock 7,500 0.00 75,215 D
2024-12-31 Monahan Joseph Officer M-Exempt D Restricted Stock Units 73,750 0.00 73,750 D
2024-12-31 Loerop James Officer M-Exempt D Restricted Stock Units 73,750 0.00 73,750 D
2024-12-31 Balthaser Kevin Officer M-Exempt A Common Stock 73,750 0.00 98,447 D
2024-12-10 Monahan Joseph Officer G-Gift D Common Stock 15,000 0.00 171,783 D
2024-12-04 Walker Neal Director / Officer M-Exempt A Common Stock 118,840 1.52 180.6K 1,501,973 D
2024-12-02 Davis Hugh M. Director / Officer A-Award A Restricted Stock Units 107,000 0.00 107,000 D
2024-12-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,466 0.00 1,385,854 D
2024-11-19 Mehra Anand Director P-Purchase A Common Stock 666,666 2.25 1.50M 710,030 D
2024-11-18 Davis Hugh M. 0 0.00 0
2024-11-18 Biosion, Inc. 10% Owner Warrants (right to buy) 11,281,985 0.00 1.1K 0 D
2024-11-01 Walker Neal Director / Officer F-InKind D Common Stock 2,721 2.09 5.7K 1,376,388 D
2024-10-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,467 0.00 1,372,364 D
2024-09-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,466 0.00 1,365,619
2024-09-01 Balthaser Kevin Officer M-Exempt A Common Stock 1,000 0.00 24,983
2024-08-09 Walker Neal Director / Officer M-Exempt D Employee Stock Option (right to buy) 43,548 0.72 31.4K 0
2024-08-05 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 206,025 1.24 256.4K 14,250,000
2024-08-02 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 167,544 1.29 216.4K 14,043,975
2024-08-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,467 0.00 85,200
2024-07-31 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 100,000 1.33 132.6K 13,876,421
2024-07-30 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 173,730 1.30 226.4K 13,776,421
2024-07-22 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 17,716 1.33 23.6K 13,602,691
2024-07-19 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 6,689 1.30 8.7K 13,584,975
2024-07-18 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 130,317 1.30 169.6K 13,578,286
2024-07-05 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 123,017 1.15 141.3K 13,447,969
2024-07-03 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 143,288 1.16 166.1K 13,324,952
2024-07-02 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 86,092 1.14 98.5K 13,181,664
2024-07-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,467 0.00 1,308,582
2024-07-01 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 107,434 1.14 122.2K 13,095,572
2024-06-28 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 801,000 1.12 896.6K 12,588,134
2024-06-27 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 235,000 1.15 271.3K 11,787,134
2024-06-18 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 50,000 1.13 56.5K 11,552,134
2024-06-17 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 150,000 1.13 169.5K 11,502,134
2024-06-14 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 345,000 1.17 402.2K 11,352,134
2024-06-13 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 500,000 1.15 575.0K 11,007,134
2024-06-12 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 82,579 1.14 94.1K 10,478,513
2024-06-11 Leonard Braden Michael 10% Owner P-Purchase A Common Stock 1,000,000 1.08 1.08M 10,395,934
2024-06-06 SCHIFF ANDREW N Director A-Award A Restricted Stock Units 4,793 0.00 4,793
2024-06-06 Molineaux Christopher P. Director A-Award A Stock Option (Right to Buy) 15,750 1.03 16.2K 15,750
2024-06-06 Mehra Anand Director A-Award A Stock Option (Right to Buy) 15,750 1.03 16.2K 15,750
2024-06-06 MILANO VINCENT Director A-Award A Stock Option (Right to Buy) 15,750 1.03 16.2K 15,750
2024-06-06 Humphries William D. Director A-Award A Restricted Stock Units 4,793 0.00 4,793
2024-06-06 GOWEN MAXINE Director A-Award A Stock Option (Right to Buy) 15,750 1.03 16.2K 15,750
2024-06-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,466 0.00 104,134
2024-06-01 SCHIFF ANDREW N Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 Reasons Bryan M. Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 Powell Andrew Kenneth William Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 Molineaux Christopher P. Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 Mehra Anand Director M-Exempt A Common Stock 4,660 0.00 43,364
2024-06-01 MILANO VINCENT Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 Humphries William D. Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-06-01 GOWEN MAXINE Director M-Exempt D Restricted Stock Units 4,660 0.00 0
2024-05-01 Walker Neal Director / Officer M-Exempt A Common Stock 9,467 0.00 1,295,155
2024-04-01 Walker Neal Director / Officer M-Exempt D Restricted Stock Units 9,467 0.00 123,067
2024-03-04 Powell Andrew Kenneth William Director P-Purchase A Common Stock 6,000 1.25 7.5K 28,863
2024-03-02 Monahan Joseph Officer M-Exempt A Common Stock 12,500 0.00 190,314
2024-03-02 Balthaser Kevin Officer F-InKind D Common Stock 427 1.24 529.48 23,983
2024-03-01 Walker Neal Director / Officer F-InKind D Common Stock 3,223 1.24 4.0K 1,279,445
2024-03-01 Powell Andrew Kenneth William Director P-Purchase A Common Stock 8,500 1.23 10.5K 22,863
2024-03-01 Monahan Joseph Officer M-Exempt D Restricted Stock Units 10,925 0.00 21,850
2024-03-01 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 1,100 0.00 1,100
2024-02-07 Leonard Braden Michael 10% Owner I Common Stock 0 0.00 9,395,934
2024-02-01 Walker Neal Director / Officer A-Award A Restricted Stock Units 142,000 0.00 142,000
2024-02-01 Monahan Joseph Officer A-Award A Restricted Stock Units 59,000 0.00 59,000
2024-02-01 Loerop James Officer A-Award A Restricted Stock Units 147,500 0.00 147,500
2024-02-01 Balthaser Kevin Officer A-Award A Restricted Stock Units 59,000 0.00 59,000
2024-01-01 Manion Douglas J. Director / Officer M-Exempt D Restricted Stock Units 27,000 0.00 81,000
2024-01-01 Balthaser Kevin Officer F-InKind D Common Stock 2,536 1.05 2.7K 20,425
2023-10-23 Monahan Joseph Officer S-Sale D Common Stock 6,000 5.08 30.5K 129,724
2023-09-06 Balthaser Kevin Officer P-Purchase A Common Stock 9,490 7.90 75.0K 15,461
2023-09-01 Balthaser Kevin Officer M-Exempt A Common Stock 1,000 0.00 6,256
2023-08-28 Loerop James Officer P-Purchase A Common Stock 14,705 6.80 100.0K 21,688
2023-08-21 Monahan Joseph Officer S-Sale D Common Stock 6,000 7.32 43.9K 135,724
2023-08-01 Manion Douglas J. Director / Officer M-Exempt A Common Stock 15,575 0.00 28,375
2023-07-01 Cawkwell Gail Officer M-Exempt A Common Stock 15,000 0.00 15,000
2023-06-20 Monahan Joseph Officer S-Sale D Common Stock 6,000 10.28 61.7K 141,724
2023-06-20 Molineaux Christopher P. Director M-Exempt A Common Stock 16,500 1.41 23.3K 48,503
2023-06-15 Molineaux Christopher P. Director M-Exempt D Stock Option (right to buy) 51 0.72 36.72 0
2023-06-02 SCHIFF ANDREW N Director M-Exempt D Restricted Stock Units 4,507 0.00 0
2023-06-02 Reasons Bryan M. Director M-Exempt A Common Stock 4,507 0.00 24,072
2023-06-02 Powell Andrew Kenneth William Director M-Exempt A Common Stock 4,507 0.00 14,363
2023-06-02 Molineaux Christopher P. Director M-Exempt D Restricted Stock Units 4,507 0.00 0
2023-06-02 Mehra Anand Director M-Exempt A Common Stock 4,507 0.00 38,704
2023-06-02 MILANO VINCENT Director M-Exempt A Common Stock 4,507 0.00 7,863
2023-06-02 Humphries William D. Director M-Exempt D Restricted Stock Units 4,507 0.00 0
2023-06-02 GOWEN MAXINE Director M-Exempt D Restricted Stock Units 4,507 0.00 0
2023-06-01 SCHIFF ANDREW N Director A-Award A Restricted Stock Units 4,660 0.00 4,660
2023-06-01 Reasons Bryan M. Director A-Award A Restricted Stock Units 4,660 0.00 4,660
2023-06-01 Powell Andrew Kenneth William Director A-Award A Stock Option (Right to Buy) 15,750 8.70 137.0K 15,750
2023-06-01 Molineaux Christopher P. Director A-Award A Stock Option (Right to Buy) 15,750 8.70 137.0K 15,750
2023-06-01 Mehra Anand Director A-Award A Restricted Stock Units 4,660 0.00 4,660
2023-06-01 MILANO VINCENT Director A-Award A Stock Option (Right to Buy) 15,750 8.70 137.0K 15,750
2023-06-01 Humphries William D. Director A-Award A Stock Option (Right to Buy) 15,750 8.70 137.0K 15,750
2023-06-01 GOWEN MAXINE Director A-Award A Restricted Stock Units 4,660 0.00 4,660
2023-03-17 Manion Douglas J. Director / Officer P-Purchase A Common Stock 6,300 7.86 49.5K 12,800
2023-03-09 Manion Douglas J. Director / Officer P-Purchase A Common Stock 6,500 7.74 50.3K 6,500
2023-03-03 Walker Neal Director S-Sale D Common Stock 30,240 12.63 382.1K 1,273,202
2023-03-03 Monahan Joseph Officer S-Sale D Common Stock 16,037 12.63 202.6K 147,724
2023-03-03 Balthaser Kevin Officer S-Sale D Common Stock 894 12.63 11.3K 5,256
2023-03-02 Walker Neal Director M-Exempt D Restricted Stock Units 18,254 0.00 18,254
2023-03-02 Monahan Joseph Officer M-Exempt D Restricted Stock Units 12,500 0.00 12,500
2023-03-02 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 1,500 0.00 1,500
2023-03-01 Walker Neal Director M-Exempt D Restricted Stock Units 96,150 0.00 0
2023-03-01 Monahan Joseph Officer M-Exempt A Common Stock 10,925 0.00 166,061
2023-03-01 Balthaser Kevin Officer M-Exempt D Restricted Stock Units 2,375 0.00 7,125
2023-02-15 Monahan Joseph Officer S-Sale D Common Stock 5,000 13.06 65.3K 91,386
2023-02-08 Loerop James Officer S-Sale D Common Stock 4,267 13.89 59.3K 6,983
2023-02-02 Walker Neal Director S-Sale D Common Stock 200 17.54 3.5K 1,175,763
2023-02-01 Walker Neal Director S-Sale D Common Stock 25,000 16.75 418.7K 1,180,763
2023-02-01 Monahan Joseph Officer A-Award A Restricted Stock Units 30,000 0.00 30,000
2023-02-01 Manion Douglas J. Director / Officer A-Award A Restricted Stock Units 108,000 0.00 108,000
2023-02-01 Loerop James Officer M-Exempt D Restricted Stock Units 11,250 0.00 33,750
2023-02-01 Cawkwell Gail Officer A-Award A Restricted Stock Units 30,000 0.00 30,000
2023-02-01 Balthaser Kevin Officer A-Award A Restricted Stock Units 30,000 0.00 30,000
2023-01-04 Walker Neal Director S-Sale D Common Stock 15,000 14.89 223.3K 1,205,763
2023-01-03 Walker Neal Director S-Sale D Common Stock 1,618 16.16 26.1K 1,220,763
2023-01-01 Balthaser Kevin Officer D Restricted Stock Units 9,500 0.00
2022-12-15 Monahan Joseph Officer S-Sale D Common Stock 5,000 15.88 79.4K 96,386
2022-11-14 SCHIFF ANDREW N Director S-Sale D Common Stock 1,371 17.08 23.4K 434,455
2022-11-11 SCHIFF ANDREW N Director S-Sale D Common Stock 41,160 17.06 702.2K 435,826
2022-11-10 SCHIFF ANDREW N Director S-Sale D Common Stock 11,395 17.02 194.0K 476,986
2022-11-08 Powell Andrew Kenneth William Director G-Gift D Common Stock 4,000 0.00 9,856
2022-10-26 SCHIFF ANDREW N Director S-Sale D Common Stock 14,540 17.01 247.3K 488,381
2022-10-25 SCHIFF ANDREW N Director S-Sale D Common Stock 12,018 17.02 204.5K 502,921
2022-10-24 SCHIFF ANDREW N Director S-Sale D Common Stock 14,616 17.01 248.6K 514,939
2022-10-18 SCHIFF ANDREW N Director S-Sale D Common Stock 32,093 16.89 542.0K 529,555
2022-10-17 SCHIFF ANDREW N Director S-Sale D Common Stock 19,944 16.05 320.1K 561,648
2022-10-17 Monahan Joseph Officer S-Sale D Common Stock 5,000 15.98 79.9K 101,386
2022-10-07 SCHIFF ANDREW N Director S-Sale D Common Stock 7,324 16.16 118.3K 581,592
2022-10-06 SCHIFF ANDREW N Director S-Sale D Common Stock 37,839 16.54 625.7K 588,916
2022-10-04 SCHIFF ANDREW N Director S-Sale D Common Stock 7,700 16.01 123.3K 626,755
2022-08-01 Manion Douglas J. Officer A-Award A Employee Stock Option (Right to Buy) 217,800 0.00 217,800
2022-07-01 Cawkwell Gail Officer A-Award A Employee Stock Option (Right to Buy) 210,000 13.83 2.90M 210,000
2022-06-27 Cawkwell Gail Officer 0 0.00 0
2022-06-17 SCHIFF ANDREW N Director S-Sale D Common Stock 19,565 15.14 296.3K 0
2022-06-03 SCHIFF ANDREW N Director M-Exempt A Common Stock 3,356 0.00 19,565
2022-06-03 Reasons Bryan M. Director M-Exempt A Common Stock 3,356 0.00 19,565
2022-06-03 Powell Andrew Kenneth William Director M-Exempt A Common Stock 3,356 0.00 13,856
2022-06-03 Molineaux Christopher P. Director M-Exempt D Restricted Stock Units 3,356 0.00 0
2022-06-03 Mehra Anand Director M-Exempt A Common Stock 3,356 0.00 34,197
2022-06-03 MILANO VINCENT Director M-Exempt D Restricted Stock Units 3,356 0.00 0
2022-06-03 GOWEN MAXINE Director M-Exempt A Common Stock 3,356 0.00 7,794
2022-06-02 SCHIFF ANDREW N Director M-Exempt D Restricted Stock Units 3,356 0.00 0
2022-06-02 Reasons Bryan M. Director A-Award A Stock Option (Right to Buy) 15,750 0.00 15,750

Executive team

Top executives
EBIT / Employee
-10.6K
Shares Outstanding
120.60M

Executive compensation

Executive compensation (annual)
# Year Executive Salary Bonus Stock award Option award Incentive Other Total % Stock-
based
Filing
1 2025 Neal Walker Chief Executive Officer 615.0K 828.4K 1.58M 350.6K 3.38M 71.40%
2 2025 Kevin Balthaser Chief Financial Officer 446.0K 310.6K 548.4K 171.7K 14.0K 1.49M 57.63%
3 2025 James Loerop 416.0K 336.8K 520.1K 160.2K 14.0K 1.45M 59.22%
4 2024 Hugh Davis President and Chief Operating Officer 62.5K 423.7K 1.08M 30.6K 1.7K 1.60M 94.06%
5 2024 Neal Walker Chief Executive Officer 477.4K 170.4K 421.6K 372.4K 3.3K 1.45M 40.96%
6 2024 Neal Walker Interim Chief Executive Officer 477.4K 170.4K 421.6K 372.4K 3.3K 1.45M 40.96%
7 2024 Kevin Balthaser Chief Financial Officer 444.0K 247.8K 179.0K 217.6K 13.8K 1.10M 38.72%
8 2024 Kevin Balthaser Chief Financial Officer 444.0K 247.8K 179.0K 217.6K 13.8K 1.10M 38.72%
9 2024 Douglas Manion Former Chief Executive Officer and President 27.1K 829.0K 856.1K 0.00%
10 2023 Douglas Manion Former President and Chief Executive Officer 600.0K 1.83M 4.51M 198.0K 13.2K 7.16M 88.67%
11 2023 Douglas Manion Former Chief Executive Officer and President 600.0K 1.83M 4.51M 198.0K 13.2K 7.16M 88.67%
12 2023 Gail Cawkwell Former Chief Medical Officer 490.0K 509.1K 1.25M 137.2K 13.2K 2.40M 73.35%
13 2023 Kevin Balthaser Chief Financial Officer 444.0K 509.1K 1.25M 124.3K 13.2K 2.34M 75.20%
14 2023 James Loerop Chief Business Officer 435.0K 509.1K 1.25M 121.8K 13.2K 2.33M 75.57%
15 2023 Joseph Monahan Chief Scientific Officer 374.4K 509.1K 1.25M 104.8K 13.2K 2.26M 78.17%
16 2022 Neal Walker Former Chief Executive Officer 589.7K 1.43M 3.45M 353.8K 12.2K 5.84M 83.63%
17 2022 Gail Cawkwell Former Chief Medical Officer 247.3K 25.0K 896.4K 2.03M 98.9K 800.00 3.30M 88.72%
18 2022 Gail Cawkwell Chief Medical Officer 247.3K 25.0K 896.4K 2.03M 98.9K 3.30M 88.75%
19 2022 Douglas Manion Former President and Chief Executive Officer 204.2K 848.5K 2.07M 82.2K 3.20M 91.06%
20 2022 Douglas Manion President and Chief Operating Officer 204.2K 848.5K 2.07M 82.2K 3.20M 91.06%
21 2022 Frank Ruffo Former Chief Financial Officer 417.8K 705.6K 1.87M 167.1K 12.2K 3.17M 81.19%
22 2022 Joseph Monahan Chief Scientific Officer 420.0K 652.9K 1.57M 168.0K 12.0K 2.82M 78.75%
23 2021 Neal Walker President and Chief Executive Officer 566.5K 1.76M 4.13M 387.5K 11.6K 6.85M 85.91%
24 2021 Neal Walker Former Chief Executive Officer 566.5K 1.76M 4.13M 387.5K 11.6K 6.85M 85.91%
25 2021 Joseph Monahan Chief Scientific Officer 350.0K 4.81M 154.7K 10.6K 5.33M 90.33%
26 2021 Kamil Ali-Jackson Former Chief Legal Officer 391.4K 683.3K 1.61M 2.01M 4.69M 48.86%
27 2021 Frank Ruffo Former Chief Financial Officer 401.7K 798.8K 1.87M 177.6K 11.6K 3.26M 81.89%
28 2021 Frank Ruffo Chief Financial Officer 401.7K 798.8K 1.87M 177.6K 11.6K 3.26M 81.89%
29 2021 David Gordon Former Chief Medical Officer 424.5K 683.3K 1.61M 206.7K 2.92M 78.39%
30 2020 Neal Walker Former Chief Executive Officer 423.8K 535.8K 231.8K 407.9K 11.4K 1.61M 47.66%
31 2020 Neal Walker President and Chief Executive Officer 423.8K 535.8K 231.8K 407.9K 11.4K 1.61M 47.66%
32 2020 Frank Ruffo Former Chief Financial Officer 390.0K 125.5K 105.4K 179.4K 11.4K 811.6K 28.44%
33 2020 Frank Ruffo Chief Financial Officer 390.0K 125.5K 105.4K 179.4K 11.4K 811.6K 28.44%
34 2020 Kamil Ali-Jackson Chief Legal Officer 380.0K 117.1K 84.3K 174.8K 11.9K 768.0K 26.22%
35 2020 Kamil Ali-Jackson Former Chief Legal Officer 380.0K 117.1K 84.3K 174.8K 11.4K 767.6K 26.24%
36 2020 David Gordon Former Chief Medical Officer 412.1K 41.8K 105.4K 189.6K 11.4K 760.2K 19.36%
37 2019 Neal Walker President and Chief Executive Officer 499.9K 2.43M 203.9K 11.2K 3.15M 77.30%
38 2019 David Gordon, MB ChB Chief Medical Officer 406.0K 843.6K 113.7K 9.4K 1.37M 61.46%
39 2019 David Gordon Former Chief Medical Officer 406.0K 843.6K 113.7K 8.9K 1.37M 61.48%
40 2019 Frank Ruffo Chief Financial Officer 390.0K 652.0K 109.2K 11.2K 1.16M 56.09%
41 2018 Neal Walker President and Chief Executive Officer 550.0K 954.3K 2.63M 221.1K 11.7K 4.36M 82.06%
42 2018 David Gordon, MB ChB Chief Medical Officer 244.4K 468.7K 1.33M 67.9K 358.00 2.12M 85.22%
43 2018 Stuart Shanler, M.D. Chief Scientific Officer 400.0K 342.4K 938.0K 116.4K 11.7K 1.81M 70.80%
44 2017 Neal Walker President and Chief Executive Officer 510.0K 288.2K 11.4K 809.6K 0.00%
45 2017 Christopher Powala Chief Regulatory and Development Officer 385.0K 139.8K 11.4K 536.2K 0.00%
46 2017 Stuart Shanler, M.D. Chief Scientific Officer 380.0K 142.6K 11.4K 534.1K 0.00%
47 2016 Neal Walker President and Chief Executive Officer 420.0K 701.8K 3.26M 273.0K 11.1K 4.67M 84.91%
48 2016 Kamil Ali-Jackson Chief Legal Officer 320.0K 401.0K 1.86M 128.8K 11.7K 2.73M 83.10%
49 2016 Christopher Powala Chief Regulatory and Development Officer 345.0K 300.8K 1.40M 120.8K 11.7K 2.18M 78.06%
50 2016 Christopher Powala Chief Operating Officer 345.0K 300.8K 1.40M 120.8K 11.7K 2.18M 78.06%
51 2015 Neal Walker President and Chief Executive Officer 344.9K 335.6K 4.71M 138.0K 11.1K 5.54M 91.08%
52 2015 Christopher Powala Chief Operating Officer 305.3K 186.4K 1.84M 91.6K 11.9K 2.43M 83.20%
53 2015 Stuart Shanler Chief Scientific Officer 287.5K 166.3K 1.71M 86.3K 45.3K 2.30M 81.75%
54 2014 Neal Walker President and Chief Executive Officer 339.9K 241.4K 102.0K 11.0K 694.3K 34.77%
55 2014 Stuart Shanler Chief Scientific Officer 283.3K 77.6K 85.0K 45.2K 491.0K 15.80%
56 2014 Christopher Powala Chief Operating Officer 300.8K 79.9K 90.2K 11.7K 482.6K 16.55%
CEO compensation breakdown

Proxy statements

Proxy statements (DEF 14A)
Filing date Form type Filing
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2025-04-24 DEFA14A
2025-04-24 DEF 14A
2025-04-14 PRE 14A

Recent SEC filings

Recent SEC filings
Filing date Form type Filing
2026-05-07 8-K
2026-05-07 10-Q
2026-05-05 4
2026-04-28 8-K
2026-04-27 SC 13G/A
2026-04-27 4
2026-04-23 DEFA14A
2026-04-23 DEF 14A
2026-04-23 ARS
2026-04-07 SC 13G

Executive team

NameTitleCompensationGender
Neal S. Walker Co-Founder, Chief Executive Officer & Chairman 965.6K
Kevin Balthaser Chief Financial Officer 631.7K male
James Loerop Chief Business Officer 590.2K male
Hugh Davis President, Chief Operating Officer & Director 555.5K
Roland Kolbeck Chief Scientific Officer 492.4K
Jesse W. Hall Chief Medical Officer 371.2K
Steve Tucker Executive Vice President of Project Leadership male
Ajay Aggarwal Senior Vice President of Clinical Development male
William C. Roberts Senior Vice President of Corporate Communications & Investor Relations male
Jon Jacobsen Senior Vice President of Chemistry
Matthew Rothman General Counsel & Corporate Secretary male
Meghan Dunsmore Senior Vice President of Finance female
ESG Rating
B
MEDICAL - DIAGNOSTICS & RESEARCH
2025
E (Environmental)
76.8 / 61.3
Company / Sector avg.
S (Social)
79.4 / 65.4
Company / Sector avg.
G (Governance)
75.7 / 64.9
Company / Sector avg.
ESG Total
77.3 / 63.8
Company / Sector avg.
ESG Score History MEDICAL - DIAGNOSTICS & RESEARCH
Benchmark vs Sector
Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits