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Akeso, Inc. (9926.HK)

HKD95.85 +0.60 (+0.63%)
CN HKSE Healthcare Biotechnology
Address No. 6, Shennong Road 528437
Zhongshan, CN
CEO Baiyong Li
IPO 2020-04-24
ISIN KYG0146B1032

Explore sections of this company profile

Description

Akeso, Inc. is a biopharmaceutical enterprise dedicated to the discovery, development, manufacturing, and commercialization of therapeutic solutions. The company boasts a diverse pipeline, with a significant focus on oncology. Its cancer-focused treatments include AK104, a PD-1/CTLA-4 bi-specific antibody in development for various malignancies such as cervical cancer, gastric cancer (GC), gastroesophageal junction (GEJ) adenocarcinoma, hepatocellular carcinoma (HCC), non-small cell lung cancer (NSCLC), small cell lung cancer (SCLC), nasopharyngeal carcinoma (NPC), clear cell renal cell carcinoma, and other solid tumors. Another bi-specific antibody, AK112, targets PD-1/VEGF and is being developed for solid and gynecological tumors, NSCLC, SCLC, and triple-negative breast cancer (TNBC). Akeso also has several monoclonal antibodies in its oncology portfolio: AK105, a PD-1 monoclonal antibody, is aimed at NSCLC, NPC, relapsed/refractory classic Hodgkin's lymphoma (R/R cHL), HCC, head and neck cancer, thyroid cancer, mesothelioma, thymic cancer, esophageal squamous cell carcinoma (ESCC), urothelial carcinoma (UC), GC, GEJ, cholangiocarcinoma, neuroendocrine tumors, and mismatch repair deficient solid tumors. AK117, a CD47 monoclonal antibody, is being investigated for myelodysplastic syndrome, acute myeloid leukemia, GC, GEJ, ESCC, TNBC, head and neck squamous cell carcinoma (HNSCC), R/R cHL, NPC, NSCLC, as well as general solid tumors and lymphomas. AK119, a CD73 monoclonal antibody, is under development for solid tumors. AK109, a VEGFR-2 monoclonal antibody, targets solid tumors and gastric cancer. Beyond oncology, Akeso is developing treatments for immunological and metabolic conditions: AK120, an IL-4R monoclonal antibody, for moderate-to-severe atopic dermatitis, asthma, and eosinophilic esophagitis. AK101, an IL-12/IL-23 monoclonal antibody, for moderate-to-severe psoriasis and ulcerative colitis. AK111, an IL-17 monoclonal antibody, for moderate-to-severe psoriasis and ankylosing spondylitis. AK102, a PCSK9 monoclonal antibody, designed to treat hypercholesterolemia. Its preclinical pipeline features AK127, a TIGIT monoclonal antibody for solid tumors, and AK115, an NGF monoclonal antibody. Akeso, Inc. collaborates with key partners including Pfizer Pharmaceuticals, AstraZeneca Pharmaceuticals, and the MD Anderson Medical Institute. The company was established in 2012 and operates from its headquarters in Zhongshan, People's Republic of China.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
HKD95.85 +0.60 (+0.63%)
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Volume Profile
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Liquidity & share structure
Average Volume
15M
Beta
0.00
Float Shares
709.76M
Free Float %
77.2%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+6.97% +1.81% -13.03% +10.48% -3.91% +4.51% +40.93% +239.86% +82.68% +386.01% +386.01%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
95.85
Ratings Trend (MoM) 87% Bullish
Rating 2026-05 Change
Strong Buy 3 0
Buy 17 0
Hold 3 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
8.63
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
2 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +40.2% Q4'25: +90.4% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    -100.0% Q4'25: +1.7% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -53.7% Q4'25: -70.4% (vs Q4'23)
  • EBIT margin Biotechnology: +0.0%
    -29.6% Q4'25: -29.7% (vs Q4'23)
  • ROIC Biotechnology: -16.1%
    -20.3% Q4'25: -44.4% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    +6.1% Q4'25: +8.7% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -5.18× Q4'25: -2.37× (vs Q4'23)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.06) × ERP
WACC = 95% × Ke + 5% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 95.85
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
17 Rev. Ana.
13 EPS Ana.
Dec 2027
16 Rev. Ana.
15 EPS Ana.
Dec 2028
14 Rev. Ana.
12 EPS Ana.
Dec 2029
9 Rev. Ana.
10 EPS Ana.
Dec 2030
13 Rev. Ana.
5 EPS Ana.
Revenue
est: 25.68M (-100.0%)
225.63M
est: 510.79M (-55.8%)
837.66M
est: 869.36M (-3.6%)
4.53B
est: 1.74B (+159.6%)
2.12B
est: 2.45B (-13.5%)
2.98B
est: 3.35B (-11.1%)
5.17B
4.50B – 6.88B
+54.5% YoY
7.73B
6.01B – 10.87B
+49.5% YoY
10.90B
8.88B – 14.99B
+41.1% YoY
18.05B
14.72B – 24.83B
+65.6% YoY
24.47B
19.95B – 33.66B
+35.6% YoY
EBITDA
-1.01B
est: -4.13M (-24,280.9%)
-1.32B
est: -82.23M (-1,500.8%)
-1.27B
est: -139.95M (-809.7%)
2.17B
est: -732.40M (+396.6%)
-604.99M
est: -1.03B (+41.3%)
-880.31M
est: -1.41B (+37.4%)
-2.17B
-2.89B – -1.89B
-54.5% YoY
-3.25B
-4.57B – -2.52B
-49.5% YoY
-4.58B
-6.30B – -3.73B
-41.1% YoY
-7.59B
-10.43B – -6.18B
-65.6% YoY
-10.28B
-14.14B – -8.38B
-35.6% YoY
EBIT
-1.02B
est: -4.60M (-22,155.3%)
-1.36B
est: -91.48M (-1,391.1%)
-1.38B
est: -155.69M (-785.7%)
2.03B
est: -763.97M (+365.7%)
-730.31M
est: -1.08B (+32.1%)
-880.31M
est: -1.47B (+40.0%)
-2.27B
-3.01B – -1.97B
-54.5% YoY
-3.39B
-4.76B – -2.63B
-49.5% YoY
-4.78B
-6.57B – -3.89B
-41.1% YoY
-7.91B
-10.88B – -6.45B
-65.6% YoY
-10.73B
-14.75B – -8.74B
-35.6% YoY
Net Income
-1.04B
est: -1.06B (+1.8%)
-1.07B
est: -910.25M (-18.1%)
-1.17B
est: -1.17B (+0.5%)
2.03B
est: -684.01M (+396.5%)
-514.52M
est: -524.66M (+1.9%)
-1.08B
est: -999.72M (-8.5%)
111.45M
37.43M – 224.88M
+111.1% YoY
1.14B
694.98M – 2.06B
+923.1% YoY
2.31B
1.34B – 4.93B
+102.7% YoY
6.80B
5.17B – 10.12B
+194.5% YoY
10.03B
7.62B – 14.92B
+47.4% YoY
SGA
253.03M
est: 23.52M (+975.8%)
422.67M
est: 467.79M (-9.6%)
751.67M
est: 796.18M (-5.6%)
1.09B
est: 1.45B (-24.6%)
1.21B
est: 2.03B (-40.8%)
1.69B
est: 2.78B (-39.2%)
4.29B
3.73B – 5.70B
+54.5% YoY
6.41B
4.98B – 9.01B
+49.5% YoY
9.04B
7.37B – 12.43B
+41.1% YoY
14.97B
12.20B – 20.59B
+65.6% YoY
20.29B
16.54B – 27.91B
+35.6% YoY
EPS
-1.65
est: -1.24 (-33.0%)
-1.32
est: -1.07 (-23.4%)
-1.42
est: -1.26 (-12.3%)
2.42
est: -0.81 (+397.6%)
-0.60
est: -0.52 (-16.0%)
-1.20
est: -0.41 (-190.0%)
0.13
0.04 – 0.25
+130.2% YoY
1.34
0.77 – 2.28
+970.0% YoY
3.04
1.48 – 5.47
+127.3% YoY
7.54
5.72 – 11.21
+147.9% YoY
11.11
8.44 – 16.52
+47.4% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-28 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-27 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-26 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-22 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-21 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-20 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-19 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-18 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-15 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-06 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-05 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-04 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-29 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-15 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-2.15B
OE per share TTM
-2.32
Owner's Yield
-2.00%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
145.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-290.1K
Shares Outstanding
919.97M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Yu Xia Founder, Chief Executive Officer, President & Chairwoman 6M male
Xinfeng Zhang Senior Vice President 5M
Jing Min Senior Vice President 5M
Mingxiu Hu Senior Vice President 5M
Baiyong Li Co-Founder, Executive Vice President, CSO & Executive Director 5M
Zhongmin Wang Co-Founder, Senior Vice President & Executive Director 4M male
Peng Zhang Co-Founder, Senior Vice President & Executive Director 4M
Yong Guo Senior Vice President & Chief Commercial Officer male
Wai Yan Leung Company Secretary female
Bing C. Wang Chief Financial Officer
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits