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Senhwa Biosciences, Inc. (6492.TWO)

TWD43.50 -0.20 (-0.46%)
TW TWO Healthcare Biotechnology
Address No. 225, Peihsin Road 23143
New Taipei City, TW
CEO Jason Huang
IPO 2014-12-04
ISIN TW0006492002

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Description

Senhwa Biosciences, Inc., a pharmaceutical company established in 2012 and headquartered in New Taipei City, Taiwan, specializes in advancing novel drugs and targeted therapeutic agents. The firm is actively progressing several clinical programs. Its compound CX-5461 is undergoing various investigations, including a Phase I, open-label study assessing dose escalation, safety, pharmacokinetics, and pharmacodynamics of its intravenous administration in individuals with advanced blood cancers. CX-5461 is also in a Phase I trial for solid cancerous growths, as well as a Phase Ib expansion study focusing on solid tumors characterized by BRCA2 and/or PALB2 genetic mutations. Furthermore, CX-5461 is being evaluated in a Phase I trial alongside pidnarulex and talazoparib for patients battling metastatic castration-resistant prostate cancer. Beyond CX-5461, Senhwa is also developing several variations of CX-4945. CX-4945-CCA is participating in a Phase I/II clinical investigation, combined with gemcitabine, for treating cholangiocarcinoma. CX-4945-BCC is the subject of a Phase I, multi-center, open-label study, examining its safety and pharmacodynamic profile when administered orally twice daily to patients with advanced basal cell carcinoma. The company's CX-4945-MB compound is being explored in a Phase I/II and surgical study, led by a pediatric brain tumor consortium, for the management of recurrent SHH medulloblastoma. Lastly, CX-4945-AV06 is currently in a Phase II, double-blind, randomized, controlled study, designed to evaluate its safety and effectiveness in hospitalized adults afflicted with COVID-19.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
TWD43.50 -0.20 (-0.46%)
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Volume Profile
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Liquidity & share structure
Average Volume
282.7K
Beta
0.89
Float Shares
58.22M
Free Float %
65.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-3.66% -9.43% -15.57% -11.52% +11.22% +4.77% +24.59% -6.68% -67.42% -64.71% -54.70%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
43.50
DCF (Unlevered) 8.08 -81.4%
DCF (Levered) 7.70 -82.3%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
43.49
Safe zone
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
2 / 5
Medium
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +7.0% Q1'26: -4.0% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +9.7% Q1'26: -8.7% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -24,104.4% Q1'26: -22,805.8% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -26,005.5% Q1'26: -28,722.1% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -2,463.3% Q1'26: -2,441.0% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    0.0% Q1'26: +0.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.08× Q1'26: -0.08× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.97) × ERP
WACC = 100% × Ke + 0% × Kd (4.1%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 8.08 Current price: 43.50
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2021
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Dec 2030
1 Rev. Ana.
1 EPS Ana.
Dec 2031
1 Rev. Ana.
1 EPS Ana.
Dec 2032
1 Rev. Ana.
1 EPS Ana.
Revenue
550.0K
est: 1.00M (-45.0%)
1.31M
1.31M – 1.31M
+30.8% YoY
1.95M
1.95M – 1.95M
+49.3% YoY
2.39M
2.39M – 2.39M
+22.2% YoY
1.00M
1.00M – 1.00M
-58.1% YoY
3.56M
3.56M – 3.56M
+256.4% YoY
4.36M
4.36M – 4.36M
+22.2% YoY
EBITDA
-321.59M
est: -1.00M (-32,058.7%)
-1.31M
-1.31M – -1.31M
-30.8% YoY
-1.95M
-1.95M – -1.95M
-49.3% YoY
-2.39M
-2.39M – -2.39M
-22.2% YoY
-1.00M
-1.00M – -1.00M
+58.1% YoY
-3.56M
-3.56M – -3.56M
-256.4% YoY
-4.36M
-4.36M – -4.36M
-22.2% YoY
EBIT
-327.82M
est: -1.00M (-32,682.1%)
-1.31M
-1.31M – -1.31M
-30.8% YoY
-1.95M
-1.95M – -1.95M
-49.3% YoY
-2.39M
-2.39M – -2.39M
-22.2% YoY
-1.00M
-1.00M – -1.00M
+58.1% YoY
-3.56M
-3.56M – -3.56M
-256.4% YoY
-4.36M
-4.36M – -4.36M
-22.2% YoY
Net Income
-329.26M
est: -336.18M (+2.1%)
-260.83M
-260.83M – -260.83M
+22.4% YoY
-473.68M
-473.68M – -473.68M
-81.6% YoY
-380.66M
-380.66M – -380.66M
+19.6% YoY
-336.03M
-336.03M – -336.03M
+11.7% YoY
-337.87M
-337.87M – -337.87M
-0.5% YoY
-327.17M
-327.17M – -327.17M
+3.2% YoY
SGA
64.94M
est: 79.17M (-18.0%)
83.21M
83.21M – 83.21M
+5.1% YoY
124.26M
124.26M – 124.26M
+49.3% YoY
151.86M
151.86M – 151.86M
+22.2% YoY
63.64M
63.64M – 63.64M
-58.1% YoY
226.78M
226.78M – 226.78M
+256.4% YoY
277.14M
277.14M – 277.14M
+22.2% YoY
EPS
-3.67
est: -3.77 (+2.6%)
-2.93
-2.93 – -2.93
+22.4% YoY
-5.31
-5.31 – -5.31
-81.6% YoY
-4.27
-4.27 – -4.27
+19.6% YoY
-3.77
-3.77 – -3.77
+11.7% YoY
-3.79
-3.79 – -3.79
-0.5% YoY
-3.67
-3.67 – -3.67
+3.2% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-11 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-08 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-07 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-06 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-05 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-05-04 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-30 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-29 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-28 C 2/5 3/5 1/5 1/5 3/5 1/5 2/5
2026-04-27 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-24 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-23 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-22 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-21 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-20 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-17 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5
2026-04-16 C 2/5 3/5 1/5 1/5 2/5 1/5 2/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-247.42M
OE per share TTM
-2.77
Owner's Yield
-5.56%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
1,876.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-185.5K
Shares Outstanding
89.39M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Sarah Chang Executive Vice President, Chief Financial Officer & Accounting Supervisor 9M female
Jason Huang Acting Chief Executive Officer & Chief Medical Officer male
Joanne Lo Acting Chief Operating Officer & Business Development Director female
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits