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Chiome Bioscience Inc. (4583.T)

JPY77.00 +3.00 (+4.05%)
JP JPX Healthcare Biotechnology
Address Sumitomo Fudosan Nishi-shinjuku Bldg.No.6 151-0071
Tokyo, JP
CEO Ei Yamada
IPO 2011-12-20
ISIN JP3205350006

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Description

Chiome Bioscience Inc. engages in the research and development of drug discovery technology platforms worldwide. It operates in two segments, Drug Discovery Business and Drug Discovery Support Business. The company offers ADLib System, a technology for generating monoclonal antibodies which is used to generate antibodies for drug discovery research; and Human ADLib System, which converts chicken antibody genes to humanized antibodies. It also provides protein expression and purification services; stable cell line development services for recombinant protein and antibody production; and antibody generation services using the ADLib system. In addition, the company's product pipeline under Phase 1 trial comprises ADCT-701, an anti-dlk1 antibody for treating liver cancer; CBA-1205, an afucosylated anti-dlk1 antibody for liver cancer, lung cancer, and neuroblastoma; and CBA-1535, an anti 5T4/WAIF1 antibody for malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and triple negative breast cancer (TNBC). Further, its product pipeline under preclinical study includes PCDC, an anti- CDCP1 antibody for lung, colorectal, pancreatic, breast, and ovarian tumors; PTRY, an antibody 5T4/CD3/PD-L1 for treating malignant mesothelioma, small cell lung cancer, non-small cell lung cancer, and TNBC; BMAA, an anti-semphorin3a antibody for treating renal and other diseases; LIV-2008/2008b, an anti-TROP-2 antibody for the treatment of TNBC, lung cancer, and colorectal cancer; PFKR, an anti-CX3CR1 antibody for secondary progressive multiple sclerosis; and PXLR, an anti-CXCL1/2/3/5 antibody for the treatment of gastric, breast, and ovarian tumors. Chiome Bioscience Inc. was incorporated in 2005 and is headquartered in Tokyo, Japan.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY77.00 +3.00 (+4.05%)
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Volume Profile
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Liquidity & share structure
Average Volume
685.0K
Beta
1.87
Float Shares
65.94M
Free Float %
93.0%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% -5.26% -12.62% -21.74% -26.83% -15.89% -39.19% -57.55% -58.33% -86.67% -69.36%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

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By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
77.00
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
8.15
Safe zone
Piotroski F-Score
1 / 9
Weak
MOAT Score
2 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -24.0% Q1'26: +6.1% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +17.5% Q1'26: +16.0% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -158.9% Q1'26: +0.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -165.1% Q1'26: -157.9% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -548.2% Q1'26: -361.4% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +16.7% Q1'26: +4.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.27× Q1'26: -0.09× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.87) × ERP
WACC = 96% × Ke + 4% × Kd (4.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 77.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Revenue
280.11M
est: 250.00M (+12.0%)
252.22M
est: 250.00M (+0.9%)
259.89M
est: 200.00M (+29.9%)
212.85M
est: 200.00M (+6.4%)
447.58M
est: 430.00M (+4.1%)
480.85M
est: 600.00M (-19.9%)
712.93M
est: 730.00M (-2.3%)
630.82M
est: 750.00M (-15.9%)
682.46M
est: 800.00M (-14.7%)
780.81M
est: 1.25B (-37.5%)
EBITDA
-1.17B
est: -250.00M (-367.0%)
-929.26M
est: -250.00M (-271.7%)
-877.28M
est: -200.00M (-338.6%)
-1.53B
est: -200.00M (-666.1%)
-1.40B
est: -430.00M (-224.9%)
-1.28B
est: -600.00M (-113.3%)
-1.33B
est: -730.00M (-82.4%)
-1.26B
est: -750.00M (-67.6%)
-1.20B
est: -800.00M (-50.5%)
-1.03B
est: -1.25B (+17.6%)
EBIT
-1.27B
est: -250.00M (-408.0%)
-1.04B
est: -250.00M (-316.9%)
-887.87M
est: -200.00M (-343.9%)
-1.54B
est: -200.00M (-669.6%)
-1.40B
est: -430.00M (-226.0%)
-1.28B
est: -600.00M (-113.9%)
-1.33B
est: -730.00M (-82.8%)
-1.26B
est: -750.00M (-67.8%)
-1.21B
est: -800.00M (-50.6%)
-1.03B
est: -1.25B (+17.5%)
Net Income
-1.28B
est: -3.17B (+59.5%)
-1.49B
est: -2.86B (+47.8%)
-882.57M
est: -2.01B (+56.1%)
-1.53B
est: -2.89B (+47.0%)
-1.40B
est: -2.70B (+47.9%)
-1.29B
est: -2.25B (+42.4%)
-1.48B
est: -1.61B (+7.9%)
-1.24B
est: -1.76B (+29.3%)
-1.22B
est: -1.71B (+28.7%)
-1.02B
est: -1.17B (+12.6%)
SGA
567.06M
est: 181.48M (+212.5%)
514.63M
est: 181.48M (+183.6%)
469.90M
est: 145.18M (+223.7%)
420.06M
est: 145.18M (+189.3%)
387.52M
est: 312.14M (+24.1%)
372.31M
est: 435.54M (-14.5%)
444.59M
est: 529.91M (-16.1%)
471.90M
est: 544.43M (-13.3%)
551.86M
est: 580.72M (-5.0%)
526.98M
est: 949.29M (-44.5%)
EPS
-58.29
est: -54.40 (-7.2%)
-65.91
est: -49.10 (-34.2%)
-33.48
est: -34.50 (+3.0%)
-57.26
est: -49.70 (-15.2%)
-44.61
est: -46.30 (+3.7%)
-36.06
est: -38.60 (+6.6%)
-36.74
est: -27.60 (-33.1%)
-28.26
est: -30.20 (+6.4%)
-24.62
est: -29.40 (+16.3%)
-17.54
est: -17.20 (-2.0%)
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-18 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-15 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-14 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-13 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-12 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-11 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-08 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
902.7K
OE per share TTM
0.01
Owner's Yield
0.01%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
1.1%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-20.00M
Shares Outstanding
70.88M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Arihiko Bijohira Executive VP, COO, Chief Strategy Officer & Director male
Masamichi Koike President, Chief Executive Officer & Executive Director
Teruyo Taoka Head of Development Division & Director female
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits