Subscribe

Carna Biosciences, Inc. (4572.T)

JPY339.00 +1.00 (+0.30%)
JP JPX Healthcare Biotechnology
Address BMA, 1-5-5 Minatojima-Minamimachi 650-0047
Kobe, JP
CEO Kohichiro Yoshino
IPO 2008-03-25
ISIN JP3220550002

Explore sections of this company profile

Also trades on Other OTC · CBIXF (USD) Tokyo Stock Exchange · 4572.T (JPY)
Description

Carna Biosciences, Inc., established in Kobe, Japan in 2003, operates as a clinical-stage biopharmaceutical company. Its core focus is on discovering and developing novel drug treatments for significant unmet medical needs, particularly within the Japanese market. In addition to its drug discovery efforts, Carna Biosciences offers an array of specialized research tools. These comprise diverse kinase proteins, their corresponding substrates, comprehensive kinase protein assay kits, stable cell lines, and biotinylated kinases, which are instrumental in investigating kinase-molecule interactions. The company also delivers a wide spectrum of scientific services. These services span from in-depth profiling and various cell-based kinase assays, including NanoBRET TE and ClariCELL intracellular assays, to protein detection and interaction analysis, live-cell kinase assays, crystallization, and weak affinity chromatography. Furthermore, they provide tyrosine kinase cell-based assay services and custom synthesis of ultra-pure proteins specifically for crystallography. Its therapeutic pipeline highlights several key investigational compounds. AS-0141, an orally administered small molecule designed to inhibit CDC7 kinase, is currently undergoing preclinical studies for cancer treatment. Another small molecule, AS-0871, is advancing through Phase 1 clinical trials for inflammatory and immune disorders. Moreover, AS-1763, an orally bioavailable, non-covalent inhibitor, is in preclinical assessment for chronic lymphocytic leukemia and other B-cell malignancies. Strategic collaborations have been established with leading pharmaceutical organizations, including Johnson & Johnson, Sierra Oncology, Sumitomo Dainippon Pharma, Gilead Sciences, and BioNova Pharmaceuticals.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
Loading outlook…
Loading forecast...
Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
Loading risk profile…
Price Chart
Averages
Trend
Price
Levels
Draw
JPY339.00 +1.00 (+0.30%)
Loading historical data…
Volume Profile
Loading…
Liquidity & share structure
Average Volume
175.9K
Beta
0.29
Float Shares
16.61M
Free Float %
86.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+9.76% +16.71% +11.62% +48.71% +119.52% +14.68% +74.62% -44.32% -62.85% -84.66% -55.67%
Rolling Volatility
Loading…
Drawdown
Loading…
Relative Strength
Loading…
Monthly Returns Heatmap
From To
Loading…
Annual Monthly Returns
Loading…
Daily Returns Distribution
vs.
Loading histogram data…

Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
339.00
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-1.22
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
D+
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -9.0% Q1'26: +28.1% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +6.6% Q1'26: -2.5% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -385.2% Q1'26: +0.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -358.3% Q1'26: -249.6% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -409.3% Q1'26: -331.5% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +6.7% Q1'26: +0.3% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.34× Q1'26: -1.20× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.42) × ERP
WACC = 92% × Ke + 8% × Kd (7.3%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 339.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Revenue
1.57B
est: 1.52B (+3.2%)
811.60M
est: 800.00M (+1.4%)
657.52M
est: 683.50M (-3.8%)
754.69M
est: 750.00M (+0.6%)
3.21B
est: 3.16B (+1.4%)
1.13B
est: 1.10B (+3.0%)
2.02B
est: 1.46B (+38.0%)
1.39B
est: 1.22B (+13.7%)
1.63B
est: 3.60B (-54.8%)
636.24M
est: 3.70B (-82.8%)
579.06M
est: 3.60B (-83.9%)
EBITDA
507.60M
est: -1.16B (+143.9%)
-258.85M
est: -608.87M (+57.5%)
-714.36M
est: -520.20M (-37.3%)
-1.18B
est: -570.81M (-107.3%)
930.62M
est: -2.41B (+138.6%)
-1.08B
est: -837.19M (-29.3%)
-509.41M
est: -1.11B (+54.2%)
-1.28B
est: -928.52M (-38.3%)
-1.09B
est: -2.74B (+60.2%)
-2.14B
est: -2.85B (+24.9%)
-2.07B
est: -2.77B (+25.1%)
EBIT
488.38M
est: -1.18B (+141.5%)
-283.27M
est: -619.54M (+54.3%)
-726.48M
est: -529.32M (-37.2%)
-1.20B
est: -580.82M (-105.9%)
921.22M
est: -2.45B (+137.6%)
-1.10B
est: -851.87M (-28.6%)
-528.57M
est: -1.13B (+53.3%)
-1.32B
est: -944.80M (-39.5%)
-1.13B
est: -2.79B (+59.6%)
-2.17B
est: -2.89B (+24.9%)
-2.07B
est: -2.81B (+26.2%)
Net Income
456.39M
est: 832.82M (-45.2%)
-289.94M
est: -585.66M (+50.5%)
-737.26M
est: -1.34B (+45.1%)
-1.21B
est: -2.23B (+45.6%)
828.29M
est: 882.96M (-6.2%)
-1.11B
est: -1.83B (+39.4%)
-534.47M
est: -1.70B (+68.6%)
-1.35B
est: -2.29B (+41.0%)
-1.15B
est: 2.02B (-157.1%)
-2.18B
est: 2.30B (-194.8%)
-2.17B
SGA
409.58M
est: 795.75M (-48.5%)
467.72M
est: 418.82M (+11.7%)
463.21M
est: 357.83M (+29.5%)
507.67M
est: 392.64M (+29.3%)
740.08M
est: 1.66B (-55.3%)
523.81M
est: 575.87M (-9.0%)
571.42M
est: 765.13M (-25.3%)
602.77M
est: 638.70M (-5.6%)
663.72M
est: 1.88B (-64.8%)
654.89M
est: 4.74B (-86.2%)
2.46B
est: 4.61B (-46.6%)
EPS
52.61
est: 46.50 (+13.1%)
-31.64
est: -32.70 (+3.2%)
-78.53
est: -75.00 (-4.7%)
-125.02
est: -124.30 (-0.6%)
76.05
est: 49.30 (+54.3%)
-90.33
est: -102.30 (+11.7%)
-42.10
est: -95.15 (+55.8%)
-99.10
est: -127.70 (+22.4%)
-68.62
est: 112.70 (-160.9%)
-121.64
est: 120.20 (-201.2%)
-113.62
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-08 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-07 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-05-01 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-30 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-28 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-27 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-29.97M
OE per share TTM
-1.60
Owner's Yield
-0.39%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
3.3%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-329.4K
Shares Outstanding
19.19M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Akinori Arimura GM of Clinical Development, R&D, Chief Development Officer of CarnaBio USA & Director
Emi Yamamoto GM of Business Mgt., Accounting, HR, General Affairs, Chief Financial Officer, Director & President - CarnaBio USA female
Kohichiro Yoshino Chief Executive Officer, President & Representative Director
Kunihisa Masuoka Chief Legal Officer & Director male
Masaaki Sawa GM of Research & Development Division, Chief Scientific Officer and Director
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

Share your view on this stock and instantly see how the community has voted over the last 6 months.

These are community opinions and do not constitute buy or sell advice to act on. The results shown are based on aggregated opinions and are not an investment recommendation, nor do they intend to influence any investment decision.

Dividend history

Earnings history

Earnings reports

Stock splits