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Nxera Pharma Co., Ltd. (4565.T)

JPY943.00 +35.00 (+3.85%)
JP JPX Healthcare Biotechnology
Address PMO Hanzomon 102-0083
Tokyo, JP
CEO Christopher Cargill
IPO 2004-07-29
ISIN JP3431300007

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Also trades on Other OTC · SOLTF (USD) Tokyo Stock Exchange · 4565.T (JPY)
Description

Nxera Pharma Co., Ltd., established in Tokyo, Japan, in 1990, is a biopharmaceutical enterprise focused on the discovery, development, and commercialization of pharmaceutical solutions. The company's operations extend across multiple international markets, including Japan, Switzerland, the United States, Bermuda, and the United Kingdom. Its array of commercially available products encompasses respiratory treatments like Ultibro/Breezhaler and Seebri/Breezhaler for chronic obstructive pulmonary disease, as well as Enerzair and Breezhaler to manage asthma. Other marketed therapeutics include ORAVI, a unique formulation addressing oropharyngeal candidiasis, and PIVLAZ, prescribed for cerebral vasospasm. The firm boasts a robust pipeline of investigational medicines, featuring HTL0039732 for immuno-oncology, HTL0048149 for schizophrenia, Daridorexant targeting insomnia, and HTL0016878 for both schizophrenia and other neuropsychiatric conditions. Additional compounds under development include PF-07081532 for Type 2 diabetes mellitus and obesity, PF-07054894 for inflammatory bowel disease, PF-07258669 for anorexia, and PF-06954522 for metabolic disorders. The pipeline also contains NBI-1117569 for various neurological diseases and NBI-1117570 for central nervous system ailments. Furthermore, Nxera Pharma is advancing a GPR35 agonist in the preclinical stage for inflammatory bowel disease and other gastrointestinal conditions, alongside other early-stage drug candidates. The company maintains significant strategic collaborations with industry leaders such as AbbVie, Biohaven, Genentech Inc., GSK, Pfizer Inc., Neurocrine Biosciences Inc., Novartis International AG, and Verily.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY943.00 +35.00 (+3.85%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.21
Float Shares
73.37M
Free Float %
81.1%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-2.42% +10.18% +18.71% +38.36% +45.50% +43.60% +42.25% -57.13% -26.46% -79.85% -40.44%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
943.00
Ratings Trend (MoM) 75% Bullish
Rating 2026-05 Change
Strong Buy 1 0
Buy 5 0
Hold 2 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
1.24
Distress
Piotroski F-Score
4 / 9
Average
MOAT Score
2 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
4 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +2.7% Q1'26: +69.4% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    -157.4% Q1'26: +302.7% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -37.0% Q1'26: -17.4% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -27.9% Q1'26: +31.4% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -8.4% Q1'26: +7.9% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +0.6% Q1'26: +16.4% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -14.68× Q1'26: 3.01× (vs Q1'25)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.17) × ERP
WACC = 66% × Ke + 34% × Kd (13.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 943.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2014
actual
Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
7 Rev. Ana.
4 EPS Ana.
Dec 2027
7 Rev. Ana.
6 EPS Ana.
Dec 2028
6 Rev. Ana.
6 EPS Ana.
Dec 2029
5 Rev. Ana.
4 EPS Ana.
Dec 2030
3 Rev. Ana.
2 EPS Ana.
Revenue
2.07B
est: 3.65B (-43.3%)
3.67B
est: 8.21B (-55.3%)
8.15B
est: 19.46B (-58.1%)
18.90B
est: 7.88B (+139.9%)
6.96B
est: 4.19B (+66.0%)
3.83B
est: 4.19B (-8.6%)
9.73B
est: 11.10B (-12.4%)
8.84B
est: 9.11B (-3.0%)
17.71B
est: 16.39B (+8.1%)
15.57B
est: 14.46B (+7.7%)
12.77B
est: 23.34B (-45.3%)
28.84B
est: 32.92B (-12.4%)
29.62B
est: 32.77B (-9.6%)
39.04B
34.82B – 44.21B
+19.1% YoY
38.63B
32.43B – 44.36B
-1.0% YoY
47.09B
46.55B – 47.63B
+21.9% YoY
45.32B
39.25B – 51.68B
-3.8% YoY
47.26B
40.93B – 53.89B
+4.3% YoY
EBITDA
651.62M
est: 196.74M (+231.2%)
1.13B
est: 442.74M (+155.5%)
1.85B
est: 1.05B (+76.5%)
13.05B
est: 424.74M (+2,972.7%)
-1.44B
est: 225.85M (-735.4%)
-6.03B
est: 225.85M (-2,770.2%)
2.46B
est: 598.26M (+310.9%)
2.20B
est: 491.27M (+348.4%)
8.19B
est: 883.29M (+826.8%)
4.16B
est: 779.15M (+433.5%)
-6.58B
est: 157.64M (-4,275.3%)
-1.38B
est: 222.33M (-720.7%)
-3.91B
est: 221.34M (-1,865.6%)
263.69M
235.19M – 298.61M
+19.1% YoY
260.92M
219.07M – 299.60M
-1.0% YoY
318.05M
314.40M – 321.69M
+21.9% YoY
306.12M
265.12M – 349.05M
-3.8% YoY
319.23M
276.48M – 364.00M
+4.3% YoY
EBIT
631.27M
est: -273.02M (+331.2%)
1.03B
est: -614.40M (+268.1%)
926.00M
est: -1.46B (+163.6%)
12.13B
est: -589.42M (+2,157.6%)
-2.46B
est: -313.42M (-685.8%)
-7.40B
est: -313.42M (-2,261.5%)
969.00M
est: -830.21M (+216.7%)
853.00M
est: -681.75M (+225.1%)
6.91B
est: -1.23B (+663.6%)
2.81B
est: -1.08B (+360.1%)
-9.06B
est: -2.82B (-221.1%)
-5.36B
est: -3.98B (-34.8%)
-8.27B
est: -3.96B (-108.8%)
-4.72B
-5.34B – -4.21B
-19.1% YoY
-4.67B
-5.36B – -3.92B
+1.0% YoY
-5.69B
-5.76B – -5.63B
-21.9% YoY
-5.48B
-6.25B – -4.75B
+3.8% YoY
-5.71B
-6.52B – -4.95B
-4.3% YoY
Net Income
1.53B
est: 3.85B (-60.4%)
516.00M
est: -4.53B (+111.4%)
-1.43B
est: 12.70B (-111.3%)
9.80B
est: -2.19B (+546.5%)
-2.65B
est: -5.93B (+55.2%)
-7.95B
est: -5.93B (-34.1%)
1.43B
est: 1.52B (-5.9%)
1.48B
est: 633.33M (+133.5%)
1.02B
est: 6.44B (-84.2%)
382.00M
est: 1.37B (-72.2%)
-7.19B
est: -9.84B (+26.9%)
-4.84B
est: -2.14B (-126.1%)
-12.53B
est: -799.91M (-1,466.4%)
3.40B
2.02B – 4.78B
+524.7% YoY
680.98M
-12.93B – 13.66B
-80.0% YoY
7.67B
829.16M – 19.42B
+1,026.0% YoY
5.37B
4.43B – 6.34B
-30.0% YoY
7.49B
6.19B – 8.86B
+39.6% YoY
SGA
875.96M
est: 1.63B (-46.1%)
1.94B
est: 3.66B (-46.9%)
2.48B
est: 8.67B (-71.4%)
2.73B
est: 3.51B (-22.3%)
4.48B
est: 1.87B (+140.0%)
2.23B
est: 1.87B (+19.7%)
2.55B
est: 4.95B (-48.5%)
2.53B
est: 4.06B (-37.8%)
3.14B
est: 7.30B (-57.0%)
3.54B
est: 6.44B (-45.1%)
6.85B
est: 8.68B (-21.1%)
11.68B
est: 12.24B (-4.6%)
15.23B
est: 12.19B (+24.9%)
14.52B
12.95B – 16.45B
+19.1% YoY
14.37B
12.07B – 16.50B
-1.0% YoY
17.52B
17.32B – 17.72B
+21.9% YoY
16.86B
14.60B – 19.22B
-3.8% YoY
17.58B
15.23B – 20.05B
+4.3% YoY
EPS
31.66
est: 42.93 (-26.2%)
9.38
est: -50.43 (+118.6%)
-23.39
est: 141.56 (-116.5%)
144.98
est: -24.45 (+692.9%)
-37.55
est: -66.05 (+43.2%)
-104.22
est: -66.05 (-57.8%)
18.69
est: 16.96 (+10.2%)
18.78
est: 7.06 (+166.1%)
12.53
est: 71.80 (-82.5%)
4.67
est: 15.28 (-69.4%)
-87.17
est: -113.99 (+23.5%)
-53.92
est: -23.61 (-128.4%)
-138.80
est: -8.82 (-1,472.9%)
36.25
22.36 – 52.91
+510.8% YoY
17.41
-143.22 – 151.28
-52.0% YoY
89.97
9.18 – 215.07
+416.9% YoY
59.44
49.09 – 70.27
-33.9% YoY
83.00
68.55 – 98.13
+39.6% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-12 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-05-11 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-05-08 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-05-07 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-05-01 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-30 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-28 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-27 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-24 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-23 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-22 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-21 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-20 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-17 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5
2026-04-16 C- 1/5 1/5 1/5 1/5 1/5 1/5 4/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-4.53B
OE per share TTM
-49.30
Owner's Yield
-4.09%
Maintenance CapEx ratio
63.25%
Maint CapEx / Avg PPE
31.2%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 72 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 Dimensional - International Small Cap ETF DFIS 0.03% 1.87M 0.39%
2 iShares MSCI Japan Small-Cap ETF SCJ 0.03% 82.1K 0.50%
3 iShares MSCI Japan Small Cap UCITS ETF IDJP.L 0.03% 179.0K 0.58%
4 State Street SPDR S&P International Small Cap ETF GWX 0.03% 233.0K 0.40%
5 Schwab International Small-Cap Equity ETF SCHC 0.02% 840.4K 0.06%
6 Vanguard FTSE All-World ex-US Small-Cap ETF VSS 0.01% 1.87M 0.06%
7 iShares Currency Hedged MSCI EAFE Small-Cap ETF HSCZ 0.01% 28.4K 0.83%
8 iShares MSCI EAFE Small-Cap ETF SCZ 0.01% 1.71M 0.40%
9 Amundi MSCI Disruptive Technology UCITS ETF Acc UNIC.L 0.01% 21.5K 0.45%
10 iShares MSCI World Small-Cap ETF WSML 0.01% 71.7K 0.30%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-21.38M
Shares Outstanding
90.49M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Chris Cargill Representative Executive Officer, President, CEO & Chairman 252M male
Shinichi Tamura Founder 233M male
Hironoshin Nomura Executive Officer & Chief Financial Officer 92M male
Candelle Chong Executive Officer, Chief Executive Officer Office & Chief of Staff 87M female
Kieran Johnson Executive Officer & Chief Accounting Officer 83M male
Shinya Tsuzuki Head of Investor Relations male
Toshihiro Maeda President of Nxera Pharma Japan & Chief Operating Officer male
Kazuhiko Yoshizumi Executive Officer & Chief Compliance Officer male
Mariko Nakafuji Executive Vice President & Chief Legal Officer female
Patrik Foerch Chief Scientific Officer & President of Nxera Pharma UK male
Shinichiro Nishishita Vice President of Investor Relations & Head of Regulatory Disclosures male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits