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AnGes, Inc. (4563.T)

JPY50.00 +0.00 (+0.00%)
JP JPX Healthcare Biotechnology
Address Saito Bio-Incubator 567-0085
Ibaraki, JP
CEO Ei Yamada
IPO 2002-09-25
ISIN JP3127700007

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Also trades on Other OTC · AMGXF (USD) Tokyo Stock Exchange · 4563.T (JPY)
Description

AnGes, Inc., a biopharmaceutical firm headquartered in Ibaraki, Japan, and established in 1999, focuses on pioneering the research and development of gene-based medical solutions. Its primary therapeutic asset is Hepatocyte Growth Factor (HGF) Plasmid, an innovative gene therapy designed to address critical limb ischemia, a severe circulatory condition impacting the legs. The company's diverse pipeline also includes NF-kB Decoy Oligonucleotide, a nucleic acid medicine formulated to suppress inflammation for various ailments, including low back pain. Furthermore, AnGes is actively developing treatments for atopic dermatitis and disc degeneration, as well as specialized medical devices aimed at preventing vascular restenosis. Their development endeavors also extend to therapeutic vaccines for cervical intraepithelial neoplasia, a precursor to cervical cancer, and, through a research partnership with Osaka University, DNA vaccines targeting hypertension. AnGes fosters strategic alliances to expand its global reach and product commercialization. These collaborations include BioMarin Pharmaceutical Inc. for the Japanese market distribution of Naglazyme, a drug for mucopolysaccharidosis VI; and Mitsubishi Tanabe Pharma Corporation, which handles the marketing of HGF Plasmid for peripheral arterial disease in both the United States and Japan. Other key partners are SHIONOGI & CO., LTD. for the commercialization of topical NF-kB decoy oligonucleotide drugs for dermatological conditions, and Vical, Inc. for the development and marketing of Allovectin, a cancer treatment. Additionally, AnGes has joined forces with Osaka University to develop a coronavirus vaccine, and with Brickell Biotech, Inc. for an investigational plasmid DNA vaccine intended to prevent coronavirus across the U.S., South America, and other territories. The company, previously known as AnGes MG, Inc., officially rebranded to AnGes, Inc. in July 2017.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
JPY50.00 +0.00 (+0.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
0.63
Float Shares
385.99M
Free Float %
97.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% -1.89% -10.34% -13.33% -33.33% -18.75% -18.75% -47.47% -94.40% -92.82% -96.50%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
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Annual Monthly Returns
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Daily Returns Distribution
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
50.00
Ratings Trend (MoM)
Rating 2024-11 Change
Strong Buy 0 0
Buy 0 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-15.50
Distress
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
C-
Overall Score
1 / 5
Low
DCF Score
1 / 5
Low
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
3 / 5
Medium
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    +35.9% Q1'26: +20.4% (vs Q1'25)
  • EPS growth Biotechnology: +29.7%
    +87.9% Q1'26: +31.2% (vs Q1'25)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -644.9% Q1'26: +0.0% (vs Q1'25)
  • EBIT margin Biotechnology: +0.0%
    -588.6% Q1'26: -734.4% (vs Q1'25)
  • ROIC Biotechnology: -16.1%
    -412.1% Q1'26: -311.2% (vs Q1'25)
  • Share dilution Biotechnology: -3.4%
    +50.8% Q1'26: +26.2% (vs Q1'25)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.01× Q1'26: -0.12× (vs Q1'25)
Valuation Multiples From To
DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (0.75) × ERP
WACC = 100% × Ke + 0% × Kd (4.0%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Current price: 50.00
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2015
actual
Dec 2016
actual
Dec 2017
actual
Dec 2018
actual
Dec 2019
actual
Dec 2020
actual
Dec 2021
actual
Dec 2022
actual
Revenue
430.15M
est: 450.00M (-4.4%)
514.27M
est: 470.00M (+9.4%)
365.18M
est: 350.00M (+4.3%)
610.05M
est: 870.00M (-29.9%)
326.76M
est: 330.00M (-1.0%)
40.00M
est: 60.00M (-33.3%)
64.15M
est: 80.00M (-19.8%)
67.06M
est: 1.39B (-95.2%)
EBITDA
-4.12B
est: -450.00M (-816.4%)
-4.70B
est: -470.00M (-899.1%)
-3.26B
est: -350.00M (-831.1%)
-3.06B
est: -870.00M (-251.5%)
-3.26B
est: -330.00M (-888.8%)
-4.19B
est: -60.00M (-6,875.0%)
-13.21B
est: -80.00M (-16,408.8%)
-13.42B
est: -1.39B (-865.1%)
EBIT
-4.17B
est: -450.00M (-827.1%)
-4.76B
est: -470.00M (-913.4%)
-3.29B
est: -350.00M (-839.6%)
-3.07B
est: -870.00M (-252.3%)
-3.27B
est: -330.00M (-890.9%)
-4.19B
est: -60.00M (-6,887.7%)
-15.63B
est: -80.00M (-19,440.1%)
-16.32B
est: -1.39B (-1,073.9%)
Net Income
-4.14B
est: -18.38B (+77.5%)
-4.78B
est: -25.20B (+81.0%)
-3.76B
est: -13.08B (+71.2%)
-3.00B
est: -5.44B (+44.9%)
-3.75B
est: -6.28B (+40.3%)
-4.21B
est: -8.73B (+51.8%)
-13.68B
est: 705.98M (-2,037.1%)
-14.71B
SGA
889.74M
est: 15.99B (-94.4%)
914.59M
est: 16.70B (-94.5%)
875.71M
est: 12.44B (-93.0%)
947.45M
est: 30.91B (-96.9%)
1.29B
est: 11.73B (-89.0%)
1.82B
est: 2.13B (-14.6%)
4.86B
est: 2.84B (+70.8%)
2.10B
est: 49.39B (-95.7%)
EPS
-74.53
est: -78.10 (+4.6%)
-75.29
est: -107.10 (+29.7%)
-49.38
est: -55.60 (+11.2%)
-34.46
est: -23.10 (-49.2%)
-35.81
est: -26.70 (-34.1%)
-35.33
est: -37.10 (+4.8%)
-92.86
est: 3.00 (-3,195.3%)
-94.29
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-08 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-07 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-05-01 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-04-30 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-04-28 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-04-27 C- 1/5 1/5 1/5 1/5 3/5 1/5 1/5
2026-04-24 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-23 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-22 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-21 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-20 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-17 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5
2026-04-16 D+ 1/5 1/5 1/5 1/5 2/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
441.55M
OE per share TTM
1.91
Owner's Yield
2.11%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
133.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 1 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P International Small Cap ETF GWX 0.00% 27.1K 0.40%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-935.5K
Shares Outstanding
395.63M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Ei Yamada Chief Executive Officer, President & Representative Director
Naoya Sato Director of Administration & Director male
Yuka Murakami Accounting Department Manager
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits