AnGes, Inc. (4563.T)
Ibaraki, JP
AnGes, Inc., a biopharmaceutical firm headquartered in Ibaraki, Japan, and established in 1999, focuses on pioneering the research and development of gene-based medical solutions. Its primary therapeutic asset is Hepatocyte Growth Factor (HGF) Plasmid, an innovative gene therapy designed to address critical limb ischemia, a severe circulatory condition impacting the legs. The company's diverse pipeline also includes NF-kB Decoy Oligonucleotide, a nucleic acid medicine formulated to suppress inflammation for various ailments, including low back pain. Furthermore, AnGes is actively developing treatments for atopic dermatitis and disc degeneration, as well as specialized medical devices aimed at preventing vascular restenosis. Their development endeavors also extend to therapeutic vaccines for cervical intraepithelial neoplasia, a precursor to cervical cancer, and, through a research partnership with Osaka University, DNA vaccines targeting hypertension. AnGes fosters strategic alliances to expand its global reach and product commercialization. These collaborations include BioMarin Pharmaceutical Inc. for the Japanese market distribution of Naglazyme, a drug for mucopolysaccharidosis VI; and Mitsubishi Tanabe Pharma Corporation, which handles the marketing of HGF Plasmid for peripheral arterial disease in both the United States and Japan. Other key partners are SHIONOGI & CO., LTD. for the commercialization of topical NF-kB decoy oligonucleotide drugs for dermatological conditions, and Vical, Inc. for the development and marketing of Allovectin, a cancer treatment. Additionally, AnGes has joined forces with Osaka University to develop a coronavirus vaccine, and with Brickell Biotech, Inc. for an investigational plasmid DNA vaccine intended to prevent coronavirus across the U.S., South America, and other territories. The company, previously known as AnGes MG, Inc., officially rebranded to AnGes, Inc. in July 2017.
No mergers or acquisitions recorded for this company.
| Indicator | 1D | 1W | 2W | 3W | 1M |
|---|
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
| 1D | 5D | 1M | 3M | 6M | YTD | 1Y | 3Y | 5Y | 10Y | Max |
|---|---|---|---|---|---|---|---|---|---|---|
| +0.00% | -1.89% | -10.34% | -13.33% | -33.33% | -18.75% | -18.75% | -47.47% | -94.40% | -92.82% | -96.50% |
Revenue flow
Revenue by geography
Revenue by segment
Revenue composition
By product
By geography
Income Statement
Balance Sheet
Cash Flow Statement
Key Metrics
Financial Ratios
Employees
Financial Growth (CAGR)
Market Data
| Rating | 2024-11 | Change |
|---|---|---|
| Strong Buy | 0 | 0 |
| Buy | 0 | 0 |
| Hold | 0 | 0 |
| Sell | 0 | 0 |
| Strong Sell | 0 | 0 |
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Revenue growth Biotechnology: +1.6%+35.9% ★ Q1'26: +20.4% (vs Q1'25)
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EPS growth Biotechnology: +29.7%+87.9% ★ Q1'26: +31.2% (vs Q1'25)
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FCF margin FCF growth · Biotechnology: +16.2%-644.9% Q1'26: +0.0% (vs Q1'25)
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EBIT margin Biotechnology: +0.0%-588.6% Q1'26: -734.4% (vs Q1'25)
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ROIC Biotechnology: -16.1%-412.1% Q1'26: -311.2% (vs Q1'25)
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Share dilution Biotechnology: -3.4%+50.8% Q1'26: +26.2% (vs Q1'25)
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Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×-0.01× Q1'26: -0.12× (vs Q1'25)
| Metric |
Dec 2015 actual |
Dec 2016 actual |
Dec 2017 actual |
Dec 2018 actual |
Dec 2019 actual |
Dec 2020 actual |
Dec 2021 actual |
Dec 2022 actual |
|---|---|---|---|---|---|---|---|---|
| Revenue |
430.15M
est: 450.00M (-4.4%)
|
514.27M
est: 470.00M (+9.4%)
|
365.18M
est: 350.00M (+4.3%)
|
610.05M
est: 870.00M (-29.9%)
|
326.76M
est: 330.00M (-1.0%)
|
40.00M
est: 60.00M (-33.3%)
|
64.15M
est: 80.00M (-19.8%)
|
67.06M
est: 1.39B (-95.2%)
|
| EBITDA |
-4.12B
est: -450.00M (-816.4%)
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-4.70B
est: -470.00M (-899.1%)
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-3.26B
est: -350.00M (-831.1%)
|
-3.06B
est: -870.00M (-251.5%)
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-3.26B
est: -330.00M (-888.8%)
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-4.19B
est: -60.00M (-6,875.0%)
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-13.21B
est: -80.00M (-16,408.8%)
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-13.42B
est: -1.39B (-865.1%)
|
| EBIT |
-4.17B
est: -450.00M (-827.1%)
|
-4.76B
est: -470.00M (-913.4%)
|
-3.29B
est: -350.00M (-839.6%)
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-3.07B
est: -870.00M (-252.3%)
|
-3.27B
est: -330.00M (-890.9%)
|
-4.19B
est: -60.00M (-6,887.7%)
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-15.63B
est: -80.00M (-19,440.1%)
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-16.32B
est: -1.39B (-1,073.9%)
|
| Net Income |
-4.14B
est: -18.38B (+77.5%)
|
-4.78B
est: -25.20B (+81.0%)
|
-3.76B
est: -13.08B (+71.2%)
|
-3.00B
est: -5.44B (+44.9%)
|
-3.75B
est: -6.28B (+40.3%)
|
-4.21B
est: -8.73B (+51.8%)
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-13.68B
est: 705.98M (-2,037.1%)
|
-14.71B
|
| SGA |
889.74M
est: 15.99B (-94.4%)
|
914.59M
est: 16.70B (-94.5%)
|
875.71M
est: 12.44B (-93.0%)
|
947.45M
est: 30.91B (-96.9%)
|
1.29B
est: 11.73B (-89.0%)
|
1.82B
est: 2.13B (-14.6%)
|
4.86B
est: 2.84B (+70.8%)
|
2.10B
est: 49.39B (-95.7%)
|
| EPS |
-74.53
est: -78.10 (+4.6%)
|
-75.29
est: -107.10 (+29.7%)
|
-49.38
est: -55.60 (+11.2%)
|
-34.46
est: -23.10 (-49.2%)
|
-35.81
est: -26.70 (-34.1%)
|
-35.33
est: -37.10 (+4.8%)
|
-92.86
est: 3.00 (-3,195.3%)
|
-94.29
|
| Date | Rating | Overall | DCF | ROE | ROA | D/E | P/E | P/B |
|---|---|---|---|---|---|---|---|---|
| 2026-05-08 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-07 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-05-01 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-04-30 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-04-28 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-04-27 | C- | 1/5 | 1/5 | 1/5 | 1/5 | 3/5 | 1/5 | 1/5 |
| 2026-04-24 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-23 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-22 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-21 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-20 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-17 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
| 2026-04-16 | D+ | 1/5 | 1/5 | 1/5 | 1/5 | 2/5 | 1/5 | 1/5 |
Owner Earnings
Ownership Overview
Ownership breakdown not available.
No beneficial ownership filings recorded.
Institutional Activity (13F)
Institutional history not available.
Top holders not available.
ETF Ownership
| # | ETF | Weight | Est. AUM exposure | TER |
|---|---|---|---|---|
| 1 | State Street SPDR S&P International Small Cap ETF GWX | 0.00% | 27.1K | 0.40% |
Insider Activity
No insider activity available.
Insider history not available.
No recent insider transactions.
Executive team
Executive compensation
Executive compensation not available.
No CEO compensation history available.
Proxy statements
No proxy statements available for this company yet.
Recent SEC filings
No SEC filings available for this company yet.
Executive team
| Name | Title | Compensation | Gender |
|---|---|---|---|
| Ei Yamada | Chief Executive Officer, President & Representative Director | — | — |
| Naoya Sato | Director of Administration & Director | — | male |
| Yuka Murakami | Accounting Department Manager | — | — |
No data available for this company.
No Senate trading activity found for this company.
No House trading activity found for this company.
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Community Opinion for 4563.T
Short-term intention
Target Price Distribution
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