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Sirnaomics Ltd. (2257.HK)

HKD4.68 +0.12 (+2.63%)
HK HKSE Healthcare Biotechnology
Address 401 Professional Drive 20879
Gaithersburg, MD, HK
CEO Hung Fai Poon
IPO 2021-12-30
ISIN KYG2050P1028

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Description

Sirnaomics Ltd. is an RNA therapeutics biopharmaceutical company, founded in 2007 and headquartered in Gaithersburg, Maryland. The company is dedicated to identifying and developing innovative therapeutic compounds aimed at addressing significant medical needs across the United States and the People's Republic of China. Its leading pipeline assets include STP705, which is being investigated for conditions such as cutaneous squamous cell carcinoma in situ, basal cell carcinoma, various liver-related cancers (cholangiocarcinoma, hepatocellular carcinoma, liver metastases), as well as for keloid scar remodeling, hypertrophic scarring, and fat sculpting. Another prominent candidate, STP707, is designed to treat cholangiocarcinoma, hepatocellular carcinoma, liver metastases, metastatic cutaneous squamous cell carcinoma, non-small cell lung cancer, and both liver and lung fibrosis. Beyond these lead programs, Sirnaomics is advancing STP355 for a range of cancers; STP369 for head and neck/bladder cancers; STP779 for liver, lung, and pancreatic cancers; and STP902 for breast cancer. The company's portfolio also extends to infectious diseases with STP702 for influenza, STP908 for COVID-19, the RIM730 COVID-19 vaccine, and STP909 for HPV/cervical cancer. Furthermore, its developmental pipeline encompasses STP122G for thrombotic disorders, STP125G for hypertriglyceridemia, STP144G for complement-mediated ailments, STP133G for cardiometabolic conditions, and STP155G for hepatitis B virus.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
HKD4.68 +0.12 (+2.63%)
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Volume Profile
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Liquidity & share structure
Average Volume
143.3K
Beta
-0.04
Float Shares
81.26M
Free Float %
74.6%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
-0.50% +6.86% -7.50% -14.94% -27.54% -22.82% +54.17% -87.91% -92.40% -92.40% -92.40%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
4.68
DCF (Unlevered) 0.10 -97.9%
DCF (Levered) 0.35 -92.6%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 100% Bullish
Rating 2026-04 Change
Strong Buy 0 0
Buy 1 0
Hold 0 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
-44.78
Distress
Piotroski F-Score
2 / 9
Weak
MOAT Score
1 / 10
No MOAT
Composite Rating
C+
Overall Score
2 / 5
Medium
DCF Score
3 / 5
Medium
ROE Score
5 / 5
High
ROA Score
1 / 5
Low
D/E Score
1 / 5
Low
P/E Score
1 / 5
Low
P/Book Score
1 / 5
Low
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -100.0% Q4'25: -100.0% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    +77.3% Q4'25: +59.3% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
  • EBIT margin Biotechnology: +0.0%
  • ROIC Biotechnology: -16.1%
    Q4'25: +136.2% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    +21.9% Q4'25: +24.9% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.69× Q4'25: -0.26× (vs Q4'23)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (-0.03) × ERP
WACC = 88% × Ke + 12% × Kd (8.7%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.10 Current price: 4.68
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
Dec 2027
1 Rev. Ana.
Dec 2028
1 Rev. Ana.
Revenue
397.0K
est: 138.1K (+187.5%)
1.78M
est: 120.9K (+1,370.7%)
est: 8.99M (-100.0%)
20.68M
20.68M – 20.68M
+130.0% YoY
38.54M
38.54M – 38.54M
+86.3% YoY
66.16M
66.16M – 66.16M
+71.7% YoY
EBITDA
-72.36M
est: -27.6K (-261,957.7%)
-31.12M
est: -24.2K (-128,607.9%)
-13.53M
est: -1.80M (-652.4%)
-4.14M
-4.14M – -4.14M
-130.0% YoY
-7.71M
-7.71M – -7.71M
-86.3% YoY
-13.23M
-13.23M – -13.23M
-71.7% YoY
EBIT
-77.15M
est: -27.6K (-279,282.9%)
-35.79M
est: -24.2K (-147,931.3%)
-15.37M
est: -1.80M (-754.7%)
-4.14M
-4.14M – -4.14M
-130.0% YoY
-7.71M
-7.71M – -7.71M
-86.3% YoY
-13.23M
-13.23M – -13.23M
-71.7% YoY
Net Income
-78.69M
est: -13.03M (-503.8%)
-51.38M
est: -166.25M (+69.1%)
-14.42M
est: -208.76M (+93.1%)
— – —
+100.0% YoY
— – —
— – —
SGA
23.16M
est: 2.55M (+808.8%)
17.16M
est: 2.23M (+669.1%)
4.54M
est: 165.98M (-97.3%)
381.74M
381.74M – 381.74M
+130.0% YoY
711.32M
711.32M – 711.32M
+86.3% YoY
1.22B
1.22B – 1.22B
+71.7% YoY
EPS
-1.03
est: -0.14 (-646.5%)
-0.66
est: -1.76 (+62.5%)
-0.15
est: -2.21 (+93.2%)
— – —
+100.0% YoY
— – —
— – —
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-28 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-27 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-26 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-22 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-21 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-20 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-19 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-18 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-15 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-14 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-05-13 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-12 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-11 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-08 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-07 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-06 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-05 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-05-04 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-04-30 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-04-29 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-04-28 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-04-27 C 2/5 2/5 5/5 1/5 1/5 1/5 1/5
2026-04-24 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-23 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-22 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-21 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-20 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-17 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-16 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5
2026-04-15 C+ 2/5 3/5 5/5 1/5 1/5 1/5 1/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-30.82M
OE per share TTM
-0.38
Owner's Yield
-5.50%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
2,661.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock

This company is not held by any ETF in our universe.

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
Shares Outstanding
108.90M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Hung Fai Poon CEO & Executive Chairman 1M
Yang Lu Honorary Scientific Scientific Officer 618.9K
Yongxiang Wang Chief Production Officer 235.0K
Yun Ting Yuen Company Secretary male
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits