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Brii Biosciences Limited (2137.HK)

HKD1.05 +0.05 (+5.00%)
CN HKSE Healthcare Biotechnology
Address Building 7 100192
Beijing, CN
CEO Zhi Hong
IPO 2021-07-13
ISIN KYG1645A1094

Explore sections of this company profile

Also trades on Hong Kong Stock Exchange · 2137.HK (HKD) Other OTC · BRIBF (USD)
Description

Founded in Beijing, China, in 2017, Brii Biosciences Limited is a biopharmaceutical firm dedicated to discovering and developing innovative therapies for infectious diseases and central nervous system disorders. Its diverse pipeline features: early-stage (Phase 1) compounds BRII-778 and BRII-732 for treating HIV; a multifaceted approach to Hepatitis B (HBV) including a Phase 2 combination study of BRII-179 and BRII-835, with BRII-179 (a recombinant protein-based immunotherapeutic) also in Phase 1b/2a, and BRII-835 having successfully completed Phase 2 for chronic HBV patients. The company also offers the Amubarvimab/romlusevimab combination as a treatment for COVID-19. Beyond these, Brii Biosciences is advancing BRII-296 for PPD and BRII-297 for various depressive conditions, alongside several agents targeting highly resistant infections: BRII-636, BRII-672, and BRII-693 are designed to combat multi-drug and extensively drug-resistant (MDR/XDR) gram-negative bacteria, while BRII-658 is under development for MDR/XDR tuberculosis and non-tuberculosis mycobacterial infections.

Market Cap & Enterprise Value
Merger & Acquisition History

No mergers or acquisitions recorded for this company.

Technical Outlook
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Signal Summary Loading…
Indicator 1D1W2W3W1M
Each column is computed on that timeframe's candles (1D = daily, 1W ≈ weekly, 1M ≈ monthly), not on the same last day. ▲ bullish · ▼ bearish · — neutral. The Net row counts signals per column; hover any cell (or the indicator name) to see the exact rule behind it.
Day Score & sub-scores
Statistical fingerprint & regime detail
Conditional historical analysis
Customize analysis (advanced)
Indicative levels generated algorithmically. Not financial advice.
Risk Profile
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Price Chart
Averages
Trend
Price
Levels
Draw
HKD1.05 +0.05 (+5.00%)
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Volume Profile
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Liquidity & share structure
Average Volume
1M
Beta
1.23
Float Shares
594.68M
Free Float %
82.5%
Price Performance
1D5D1M3M6M YTD1Y3Y5Y10YMax
+0.00% -4.96% -14.81% -26.28% -33.91% -18.44% -37.50% -69.41% -94.99% -94.99% -94.99%
Rolling Volatility
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Drawdown
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Relative Strength
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Monthly Returns Heatmap
From To
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Annual Monthly Returns
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Daily Returns Distribution
vs.
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Revenue flow

Revenue by geography

Revenue by segment

From To

Revenue composition

From To

By product

By geography

Financial Statements

Income Statement

Balance Sheet

Cash Flow Statement

Key Metrics

Financial Ratios

Employees

Financial Growth (CAGR)

Market Data

Price Targets & DCF
Current price
1.05
DCF (Unlevered) 0.84 -19.8%
DCF (Levered) 0.82 -21.9%

DCF figures are point estimates: small changes in growth or discount-rate assumptions move them materially. Read them as a reference, not a precise target.

Ratings Trend (MoM) 0% Bullish
Rating 2026-05 Change
Strong Buy 0 0
Buy 0 0
Hold 1 0
Sell 0 0
Strong Sell 0 0
Quality scores
Altman Z-Score
7.46
Safe zone
Piotroski F-Score
3 / 9
Average
MOAT Score
1 / 10
No MOAT
Composite Rating
B
Overall Score
3 / 5
Medium
DCF Score
4 / 5
High
ROE Score
1 / 5
Low
ROA Score
1 / 5
Low
D/E Score
4 / 5
High
P/E Score
1 / 5
Low
P/Book Score
5 / 5
High
Operational MOAT
✗ Below peers
  • Revenue growth Biotechnology: +1.6%
    -66.6% Q4'25: +12.8% (vs Q4'23)
  • EPS growth Biotechnology: +29.7%
    +57.1% Q4'25: -580.8% (vs Q4'23)
  • FCF margin FCF growth · Biotechnology: +16.2%
    -1,983.4% Q4'25: -577.7% (vs Q4'23)
  • EBIT margin Biotechnology: +0.0%
    -1,632.6% Q4'25: -664.8% (vs Q4'23)
  • ROIC Biotechnology: -16.1%
    -75.6% Q4'25: -124.3% (vs Q4'23)
  • Share dilution Biotechnology: -3.4%
    -1.2% Q4'25: -1.4% (vs Q4'23)
  • Debt / EBITDA Net debt/EBITDA · Biotechnology: 0.16×
    -0.03× Q4'25: -0.02× (vs Q4'23)
Valuation Multiples From To
Price Forecast (3Y) From To
Model
Adjust
P/E
Theoretical Return — If Invested Today

* These projections are based on analyst consensus estimates and user-defined valuation multiples. This table is for informational purposes only and does not constitute a recommendation to buy or sell any security. Past performance is not indicative of future results.

DCF Interactive Model (UFCF)
Projection years:
Market assumptions
WACC components (optional)
Ke (Cost of Equity) = Rf + β (1.26) × ERP
WACC = 99% × Ke + 1% × Kd (21.4%) × (1−t)

Modifying these values recalculates WACC automatically.

Business assumptions
Intrinsic value (base): 0.84 Current price: 1.05
Enterprise Value: Equity Value: Terminal Value: TV as % of EV:

Base values reflect the latest available data for this company and market conditions.

Consensus Estimates
Metric Dec 2022
actual
Dec 2023
actual
Dec 2024
actual
Dec 2025
actual
Dec 2026
1 Rev. Ana.
1 EPS Ana.
Dec 2027
1 Rev. Ana.
1 EPS Ana.
Dec 2028
1 Rev. Ana.
1 EPS Ana.
Dec 2029
1 Rev. Ana.
1 EPS Ana.
Revenue
51.63M
est: 161.02M (-67.9%)
56.32M
est: 35.70M (+57.8%)
54.29M
est: -77.47M (+170.1%)
18.12M
est: 28.29M (-35.9%)
310.76M
310.76M – 310.76M
+998.6% YoY
435.09M
435.09M – 435.09M
+40.0% YoY
2.17B
2.17B – 2.17B
+397.6% YoY
5.34M
5.34M – 5.34M
-99.8% YoY
EBITDA
-503.58M
est: -161.02M (-212.8%)
-168.20M
est: -35.70M (-371.1%)
-392.52M
est: 77.47M (-606.7%)
-290.29M
est: -28.29M (-926.2%)
-310.76M
-310.76M – -310.76M
-998.6% YoY
-435.09M
-435.09M – -435.09M
-40.0% YoY
-2.17B
-2.17B – -2.17B
-397.6% YoY
-5.34M
-5.34M – -5.34M
+99.8% YoY
EBIT
-513.85M
est: -161.02M (-219.1%)
-183.88M
est: -35.70M (-415.0%)
-399.50M
est: 77.47M (-615.7%)
-295.88M
est: -28.29M (-946.0%)
-310.76M
-310.76M – -310.76M
-998.6% YoY
-435.09M
-435.09M – -435.09M
-40.0% YoY
-2.17B
-2.17B – -2.17B
-397.6% YoY
-5.34M
-5.34M – -5.34M
+99.8% YoY
Net Income
-484.31M
est: -588.65M (+17.7%)
-174.83M
est: -244.43M (+28.5%)
-508.16M
est: -425.75M (-19.4%)
-216.86M
est: -187.61M (-15.6%)
-322.22M
-322.22M – -322.22M
-71.7% YoY
-314.72M
-314.72M – -314.72M
+2.3% YoY
-247.29M
-247.29M – -247.29M
+21.4% YoY
-239.79M
-239.79M – -239.79M
+3.0% YoY
SGA
80.33M
est: 250.86M (-68.0%)
57.10M
est: 91.35M (-37.5%)
203.94M
est: -198.23M (+202.9%)
101.67M
est: 72.38M (+40.5%)
795.16M
795.16M – 795.16M
+998.6% YoY
1.11B
1.11B – 1.11B
+40.0% YoY
5.54B
5.54B – 5.54B
+397.6% YoY
13.65M
13.65M – 13.65M
-99.8% YoY
EPS
-0.67
est: -0.81 (+16.9%)
-0.24
est: -0.34 (+29.1%)
-0.70
est: -0.59 (-18.7%)
-0.30
est: -0.26 (-15.4%)
-0.45
-0.45 – -0.45
-71.7% YoY
-0.44
-0.44 – -0.44
+2.3% YoY
-0.34
-0.34 – -0.34
+21.4% YoY
-0.33
-0.33 – -0.33
+3.0% YoY
Historical Ratings (3M)
Date Rating Overall DCF ROE ROA D/E P/E P/B
2026-05-29 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-28 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-27 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-26 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-22 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-21 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-20 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-19 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-18 B 3/5 4/5 1/5 1/5 4/5 1/5 5/5
2026-05-15 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-14 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-13 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-12 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-11 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-08 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-07 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-06 B- 3/5 3/5 1/5 1/5 4/5 1/5 5/5
2026-05-05 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-05-04 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-30 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-29 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-28 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-27 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-24 B- 2/5 3/5 1/5 1/5 3/5 1/5 5/5
2026-04-23 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-22 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-21 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-20 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-17 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5
2026-04-16 C+ 2/5 3/5 1/5 1/5 2/5 1/5 5/5

Owner Earnings

Owner's Earnings (history) From To
Owner alignment
Owner's Earnings TTM
-533.37M
OE per share TTM
-0.73
Owner's Yield
-64.55%
Maintenance CapEx ratio
Maint CapEx / Avg PPE
50.0%

Ownership Overview

Ownership breakdown

Ownership breakdown not available.

At a glance
Institutional holders
Total invested
Insider transactions (90d)
0
Beneficial owners (>5%)
0
Beneficial owners (>5%)

No beneficial ownership filings recorded.

Institutional Activity (13F)

Institutional ownership trend

Institutional history not available.

Top institutional holders

Top holders not available.

ETF Ownership

Top ETFs holding this stock Held by 4 ETFs in our universe
# ETF Weight Est. AUM exposure TER
1 State Street SPDR S&P Emerging Markets Small Cap ETF EWX 0.01% 67.1K 0.65%
2 Avantis Responsible Emerging Markets Equity ETF AVSE 0.00% 6.9K 0.33%
3 Avantis Emerging Markets Equity ETF AVEM 0.00% 95.0K 0.33%
4 Avantis Emerging Markets Small Cap Equity ETF AVEE 0.00% 410.74 0.42%

Insider Activity

Insider Activity — Latest Quarter

No insider activity available.

Insider buys vs sells (history)

Insider history not available.

Recent insider transactions

No recent insider transactions.

Executive team

Top executives
EBIT / Employee
-30.2K
Shares Outstanding
721.18M

Executive compensation

Executive compensation (annual)

Executive compensation not available.

CEO compensation breakdown

No CEO compensation history available.

Proxy statements

Proxy statements (DEF 14A)

No proxy statements available for this company yet.

Recent SEC filings

Recent SEC filings

No SEC filings available for this company yet.

Executive team

NameTitleCompensationGender
Zhi Hong Co-founder, Executive Chairman of the Board & Chief Executive Officer 12M
Ankang Li COO, Joint Secretary & Executive Director 6M
David Margolis Chief Medical Officer
Eleanor de Groot Chief Technology Officer
Haifeng Cao Head of China Development male
Karen Del Barrio Neuendorff Chief People Officer & Head of Human Resources female
Qing Zhu Head of Pre-clinical Sciences and Translational Research
Sarah Qiu Associate Director of Investor Relations
Susannah Cantrell Chief Business Officer
Wing Tsz FCIS Joint Company Secretary female
Brian Alvin Johns Chief Scientific Officer
ESG Score History

No data available for this company.

Senate Trading Activity

No Senate trading activity found for this company.

House Trading Activity

No House trading activity found for this company.

Market share among peers
Peer comparison — filtered group (TTM)
Your opinion

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Dividend history

Earnings history

Earnings reports

Stock splits